Jean-Luc Imler

Affiliations

Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China. Electronic address: jl.imler@ibmc-cnrs.unistra.fr.

Publications (22)

Sensing and signalling viral infection in drosophila.

Developmental and comparative immunology

Avec: Juliette Schneider ,

Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila.

Cell reports

Avec: Isaque J S de Faria , Eric R G R Aguiar , Roenick P Olmo , Juliana Alves da Silva , Laurent Daeffler , Richard W Carthew , João T Marques

2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in

Science signaling

Avec: Hua Cai , Andreas Holleufer , Bine Simonsen , Juliette Schneider , Aurélie Lemoine , Hans Henrik Gad , Jingxian Huang , Jieqing Huang , Di Chen , Tao Peng , João T Marques , Rune Hartmann , Nelson E Martins ,

Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators.

Nature communications

Avec: Friederike L Pennemann , Assel Mussabekova , Christian Urban , Alexey Stukalov , Line Lykke Andersen , Vincent Grass , Teresa Maria Lavacca , Cathleen Holze , Lila Oubraham , Yasmine Benamrouche , Enrico Girardi , Rasha E Boulos , Rune Hartmann , Giulio Superti-Furga , Matthias Habjan , Carine Meignin , Andreas Pichlmair

Investigating the Evolution of Drosophila STING-dependent Antiviral Innate Immunity by Multispecies Comparison of 2'3'-cGAMP Responses.

Molecular biology and evolution

Avec: Léna Hédelin , Antonin Thiébaut , Jingxian Huang , Xiaoyan Li , Aurélie Lemoine , Gabrielle Haas , Carine Meignin , Hua Cai , Robert M Waterhouse , Nelson Martins ,

A Transgenic Flock House Virus Replicon Reveals an RNAi Independent Antiviral Mechanism Acting in

G3 (Bethesda, Md.)

Avec: Nelson Martins , Aurélie Lemoine , Estelle Santiago , Simona Paro , Carine Meignin

Two cGAS-like receptors induce antiviral immunity in Drosophila.

Nature

Avec: Andreas Holleufer , Kasper Grønbjerg Winther , Hans Henrik Gad , Xianlong Ai , Yuqiang Chen , Lihua Li , Ziming Wei , Huimin Deng , Jiyong Liu , Ninna Ahlmann Frederiksen , Bine Simonsen , Line Lykke Andersen , Karin Kleigrewe , Louise Dalskov , Andreas Pichlmair , Hua Cai , Rune Hartmann

Protocol for the analysis of double-stranded RNAs in virus-infected insect cells using anti-dsRNA antibodies.

STAR protocols

Avec: Isaque J S de Faria , João T Marques

A novel virus-induced cyclic dinucleotide, 2'3'-c-di-GMP, mediates STING-dependent antiviral immunity in

bioRxiv : the preprint server for biology

Avec: Hua Cai , Lihua Li , Kailey Slavik , Jingxian Huang , Ting Yin , Léna Hédelin , Zhangmin Xiang , Yunyun Yang , Xiaoyan Li , Yuqiang Chen , Ziming Wei , Huimin Deng , Di Chen , Renjie Jiao , Nelson Martins , Carine Meignin , Philip Kranzusch ,

SDHi fungicides: An example of mitotoxic pesticides targeting the succinate dehydrogenase complex.

Environment international

Avec: Carolina Duarte Hospital , Arnaud Tête , Kloé Debizet , Jules Imler , Céline Tomkiewicz-Raulet , Etienne B Blanc , Robert Barouki , Xavier Coumoul , Sylvie Bortoli

Genomic analysis of two phlebotomine sand fly vectors of Leishmania from the New and Old World.

PLoS neglected tropical diseases

Avec: Frédéric Labbé , Maha Abdeladhim , Jenica Abrudan , Alejandra Saori Araki , Ricardo N Araujo , Peter Arensburger , Joshua B Benoit , Reginaldo Pecanha Brazil , Rafaela V Bruno , Gustavo Bueno da Silva Rivas , Vinicius Carvalho de Abreu , Jason Charamis , Iliano V Coutinho-Abreu , Samara G da Costa-Latgé , Alistair Darby , Viv M Dillon , Scott J Emrich , Daniela Fernandez-Medina , Nelder Figueiredo Gontijo , Catherine M Flanley , Derek Gatherer , Fernando A Genta , Sandra Gesing , Gloria I Giraldo-Calderón , Bruno Gomes , Eric Roberto Guimaraes Rocha Aguiar , James G C Hamilton , Omar Hamarsheh , Mallory Hawksworth , Jacob M Hendershot , Paul V Hickner , Panagiotis Ioannidis , Emily C Jennings , Shaden Kamhawi , Charikleia Karageorgiou , Ryan C Kennedy , Andreas Krueger , José M Latorre-Estivalis , Petros Ligoxygakis , Antonio Carlos A Meireles-Filho , Patrick Minx , Jose Carlos Miranda , Michael J Montague , Ronald J Nowling , Fabiano Oliveira , João Ortigão-Farias , Marcio G Pavan , Marcos Horacio Pereira , Andre Nobrega Pitaluga , Roenick Proveti Olmo , Marcelo Ramalho-Ortigao , José M C Ribeiro , Andrew J Rosendale , Mauricio R V Sant'Anna , Steven E Scherer , Nágila F C Secundino , Douglas A Shoue , Caroline da Silva Moraes , João Silveira Moledo Gesto , Nataly Araujo Souza , Zainulabueddin Syed , Samuel Tadros , Rayane Teles-de-Freitas , Erich L Telleria , Chad Tomlinson , Yara M Traub-Csekö , João Trindade Marques , Zhijian Tu , Maria F Unger , Jesus Valenzuela , Flávia V Ferreira , Karla P V de Oliveira , Felipe M Vigoder , John Vontas , Lihui Wang , Gareth D Weedall , Elyes Zhioua , Stephen Richards , Wesley C Warren , Robert M Waterhouse , Rod J Dillon , Mary Ann McDowell

Sensing Viral Infections in Insects: A Dearth of Pathway Receptors.

Current issues in molecular biology

Avec: Loïc Talide , Carine Meignin

cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.

Nature

Avec: Kailey M Slavik , Benjamin R Morehouse , Adelyn E Ragucci , Wen Zhou , Xianlong Ai , Yuqiang Chen , Lihua Li , Ziming Wei , Heike Bähre , Martin König , Roland Seifert , Amy S Y Lee , Hua Cai , Philip J Kranzusch

cGAS-like receptor-mediated immunity: the insect perspective.

Current opinion in immunology

Avec: Hua Cai , Carine Meignin ,

Mosquito vector competence for dengue is modulated by insect-specific viruses.

Nature microbiology

Avec: Roenick P Olmo , Yaovi M H Todjro , Eric R G R Aguiar , João Paulo P de Almeida , Flávia V Ferreira , Juliana N Armache , Isaque J S de Faria , Alvaro G A Ferreira , Siad C G Amadou , Ana Teresa S Silva , Kátia P R de Souza , Ana Paula P Vilela , Antinea Babarit , Cheong H Tan , Mawlouth Diallo , Alioune Gaye , Christophe Paupy , Judicaël Obame-Nkoghe , Tessa M Visser , Constantianus J M Koenraadt , Merril A Wongsokarijo , Ana Luiza C Cruz , Mariliza T Prieto , Maisa C P Parra , Maurício L Nogueira , Vivian Avelino-Silva , Renato N Mota , Magno A Z Borges , Betânia P Drumond , Erna G Kroon , Mario Recker , Luigi Sedda , Eric Marois , João T Marques

An evolutionary perspective to innate antiviral immunity in animals.

Cell reports

Avec: Joao T Marques , Carine Meignin ,

A single unidirectional piRNA cluster similar to the

RNA (New York, N.Y.)

Avec: Eric Roberto Guimarães Rocha Aguiar , João Paulo Pereira de Almeida , Lucio Rezende Queiroz , Liliane Santana Oliveira , Roenick Proveti Olmo , Isaque João da Silva de Faria , Arthur Gruber , Benjamin J Matthews , João Trindade Marques

The insect reservoir of biodiversity for viruses and for antiviral mechanisms.

Anais da Academia Brasileira de Ciencias

Avec: Roenick P Olmo , Nelson Eduardo Martins , Eric Roberto G R Aguiar , João T Marques ,

cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette.

Faculty reviews

Avec: Hua Cai ,

Insect decline: immediate action is needed.

Comptes rendus biologies

Avec: Hervé Jactel , Louis Lambrechts , Anna-Bella Failloux , Jean Dominique Lebreton , Yvon Le Maho , Jean-Claude Duplessy , Pascale Cossart , Philippe Grandcolas

The virus-induced cyclic dinucleotide 2'3'-c-di-GMP mediates STING-dependent antiviral immunity in Drosophila.

Immunity

Avec: Hua Cai , Lihua Li , Kailey M Slavik , Jingxian Huang , Ting Yin , Xianlong Ai , Léna Hédelin , Gabrielle Haas , Zhangmin Xiang , Yunyun Yang , Xiaoyan Li , Yuqiang Chen , Ziming Wei , Huimin Deng , Di Chen , Renjie Jiao , Nelson Martins , Carine Meignin , Philip J Kranzusch ,

Evolutionary immunology to explore original antiviral strategies.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Avec: Hua Cai , Carine Meignin , Nelson Martins

Réseau de co-auteurs

Hua Cai 9 collaborations

Carine Meignin 9 collaborations

João T Marques 5 collaborations

Nelson Martins 5 collaborations

Jingxian Huang 4 collaborations

Yuqiang Chen 4 collaborations

Lihua Li 4 collaborations

Ziming Wei 4 collaborations

Isaque J S de Faria 3 collaborations

Roenick P Olmo 3 collaborations

Aurélie Lemoine 3 collaborations

Di Chen 3 collaborations

Rune Hartmann 3 collaborations

Léna Hédelin 3 collaborations

Xiaoyan Li 3 collaborations

Xianlong Ai 3 collaborations

Huimin Deng 3 collaborations

Juliette Schneider 2 collaborations

Eric R G R Aguiar 2 collaborations

Andreas Holleufer 2 collaborations

Bine Simonsen 2 collaborations

Hans Henrik Gad 2 collaborations

Line Lykke Andersen 2 collaborations

Andreas Pichlmair 2 collaborations

Gabrielle Haas 2 collaborations

Robert M Waterhouse 2 collaborations

Ting Yin 2 collaborations

Zhangmin Xiang 2 collaborations

Yunyun Yang 2 collaborations

Renjie Jiao 2 collaborations

Roenick Proveti Olmo 2 collaborations

João Trindade Marques 2 collaborations

Flávia V Ferreira 2 collaborations

Kailey M Slavik 2 collaborations

Philip J Kranzusch 2 collaborations

Juliana Alves da Silva 1 collaboration

Laurent Daeffler 1 collaboration

Richard W Carthew 1 collaboration

Jieqing Huang 1 collaboration

Tao Peng 1 collaboration

Nelson E Martins 1 collaboration

Friederike L Pennemann 1 collaboration

Assel Mussabekova 1 collaboration

Christian Urban 1 collaboration

Alexey Stukalov 1 collaboration

Vincent Grass 1 collaboration

Teresa Maria Lavacca 1 collaboration

Cathleen Holze 1 collaboration

Lila Oubraham 1 collaboration

Yasmine Benamrouche 1 collaboration

Enrico Girardi 1 collaboration

Rasha E Boulos 1 collaboration

Giulio Superti-Furga 1 collaboration

Matthias Habjan 1 collaboration

Antonin Thiébaut 1 collaboration

Estelle Santiago 1 collaboration

Simona Paro 1 collaboration

Kasper Grønbjerg Winther 1 collaboration

Jiyong Liu 1 collaboration

Ninna Ahlmann Frederiksen 1 collaboration

Karin Kleigrewe 1 collaboration

Louise Dalskov 1 collaboration

Kailey Slavik 1 collaboration

Philip Kranzusch 1 collaboration

Carolina Duarte Hospital 1 collaboration

Arnaud Tête 1 collaboration

Kloé Debizet 1 collaboration

Jules Imler 1 collaboration

Céline Tomkiewicz-Raulet 1 collaboration

Etienne B Blanc 1 collaboration

Robert Barouki 1 collaboration

Xavier Coumoul 1 collaboration

Sylvie Bortoli 1 collaboration

Frédéric Labbé 1 collaboration

Maha Abdeladhim 1 collaboration

Jenica Abrudan 1 collaboration

Alejandra Saori Araki 1 collaboration

Ricardo N Araujo 1 collaboration

Peter Arensburger 1 collaboration

Joshua B Benoit 1 collaboration

Reginaldo Pecanha Brazil 1 collaboration

Rafaela V Bruno 1 collaboration

Gustavo Bueno da Silva Rivas 1 collaboration

Vinicius Carvalho de Abreu 1 collaboration

Jason Charamis 1 collaboration

Iliano V Coutinho-Abreu 1 collaboration

Samara G da Costa-Latgé 1 collaboration

Alistair Darby 1 collaboration

Viv M Dillon 1 collaboration

Scott J Emrich 1 collaboration

Daniela Fernandez-Medina 1 collaboration

Nelder Figueiredo Gontijo 1 collaboration

Catherine M Flanley 1 collaboration

Derek Gatherer 1 collaboration

Fernando A Genta 1 collaboration

Sandra Gesing 1 collaboration

Gloria I Giraldo-Calderón 1 collaboration

Bruno Gomes 1 collaboration

Eric Roberto Guimaraes Rocha Aguiar 1 collaboration

James G C Hamilton 1 collaboration

Omar Hamarsheh 1 collaboration

Mallory Hawksworth 1 collaboration

Jacob M Hendershot 1 collaboration

Paul V Hickner 1 collaboration

Panagiotis Ioannidis 1 collaboration

Emily C Jennings 1 collaboration

Shaden Kamhawi 1 collaboration

Charikleia Karageorgiou 1 collaboration

Ryan C Kennedy 1 collaboration

Andreas Krueger 1 collaboration

José M Latorre-Estivalis 1 collaboration

Petros Ligoxygakis 1 collaboration

Antonio Carlos A Meireles-Filho 1 collaboration

Patrick Minx 1 collaboration

Jose Carlos Miranda 1 collaboration

Michael J Montague 1 collaboration

Ronald J Nowling 1 collaboration

Fabiano Oliveira 1 collaboration

João Ortigão-Farias 1 collaboration

Marcio G Pavan 1 collaboration

Marcos Horacio Pereira 1 collaboration

Andre Nobrega Pitaluga 1 collaboration

Marcelo Ramalho-Ortigao 1 collaboration

José M C Ribeiro 1 collaboration

Andrew J Rosendale 1 collaboration

Mauricio R V Sant'Anna 1 collaboration

Steven E Scherer 1 collaboration

Nágila F C Secundino 1 collaboration

Douglas A Shoue 1 collaboration

Caroline da Silva Moraes 1 collaboration

João Silveira Moledo Gesto 1 collaboration

Nataly Araujo Souza 1 collaboration

Zainulabueddin Syed 1 collaboration

Samuel Tadros 1 collaboration

Rayane Teles-de-Freitas 1 collaboration

Erich L Telleria 1 collaboration

Chad Tomlinson 1 collaboration

Yara M Traub-Csekö 1 collaboration

Zhijian Tu 1 collaboration

Maria F Unger 1 collaboration

Jesus Valenzuela 1 collaboration

Karla P V de Oliveira 1 collaboration

Felipe M Vigoder 1 collaboration

John Vontas 1 collaboration

Lihui Wang 1 collaboration

Gareth D Weedall 1 collaboration

Elyes Zhioua 1 collaboration

Stephen Richards 1 collaboration

Wesley C Warren 1 collaboration

Rod J Dillon 1 collaboration

Mary Ann McDowell 1 collaboration

Loïc Talide 1 collaboration

Benjamin R Morehouse 1 collaboration

Adelyn E Ragucci 1 collaboration

Wen Zhou 1 collaboration

Heike Bähre 1 collaboration

Martin König 1 collaboration

Roland Seifert 1 collaboration

Amy S Y Lee 1 collaboration

Yaovi M H Todjro 1 collaboration

João Paulo P de Almeida 1 collaboration

Juliana N Armache 1 collaboration

Alvaro G A Ferreira 1 collaboration

Siad C G Amadou 1 collaboration

Ana Teresa S Silva 1 collaboration

Kátia P R de Souza 1 collaboration

Ana Paula P Vilela 1 collaboration

Antinea Babarit 1 collaboration

Cheong H Tan 1 collaboration

Mawlouth Diallo 1 collaboration

Alioune Gaye 1 collaboration

Christophe Paupy 1 collaboration

Judicaël Obame-Nkoghe 1 collaboration

Tessa M Visser 1 collaboration

Constantianus J M Koenraadt 1 collaboration

Merril A Wongsokarijo 1 collaboration

Ana Luiza C Cruz 1 collaboration

Mariliza T Prieto 1 collaboration

Maisa C P Parra 1 collaboration

Maurício L Nogueira 1 collaboration

Vivian Avelino-Silva 1 collaboration

Renato N Mota 1 collaboration

Magno A Z Borges 1 collaboration

Betânia P Drumond 1 collaboration

Erna G Kroon 1 collaboration

Mario Recker 1 collaboration

Luigi Sedda 1 collaboration

Eric Marois 1 collaboration

Joao T Marques 1 collaboration

Eric Roberto Guimarães Rocha Aguiar 1 collaboration

João Paulo Pereira de Almeida 1 collaboration

Lucio Rezende Queiroz 1 collaboration

Liliane Santana Oliveira 1 collaboration

Isaque João da Silva de Faria 1 collaboration

Arthur Gruber 1 collaboration

Benjamin J Matthews 1 collaboration

Nelson Eduardo Martins 1 collaboration

Eric Roberto G R Aguiar 1 collaboration

Hervé Jactel 1 collaboration

Louis Lambrechts 1 collaboration

Anna-Bella Failloux 1 collaboration

Jean Dominique Lebreton 1 collaboration

Yvon Le Maho 1 collaboration

Jean-Claude Duplessy 1 collaboration

Pascale Cossart 1 collaboration

Philippe Grandcolas 1 collaboration