Inna A Belyantseva

Affiliations

Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.

Publications (17)

Combined AAV-mediated gene replacement therapy improves auditory function in a mouse model of human DFNB42 deafness.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Kevin Isgrig , Alexander X Cartagena-Rivera , Hong Jun Wang , Mhamed Grati , Katharine A Fernandez , Thomas B Friedman , Wade Chien

Live-cell single-molecule fluorescence microscopy for protruding organelles reveals regulatory mechanisms of MYO7A-driven cargo transport in stereocilia of inner ear hair cells.

bioRxiv : the preprint server for biology

Avec: Takushi Miyoshi , Harshad D Vishwasrao , Mrudhula Sajeevadathan , Yasuko Ishibashi , Samuel M Adadey , Narinobu Harada , Hari Shroff , Thomas B Friedman

Biallelic variants in

medRxiv : the preprint server for health sciences

Avec: Thomas B Smith , Robert Kopajtich , Leigh A M Demain , Alessandro Rea , Huw B Thomas , Manuel Schiff , Christian Beetz , Shelagh Joss , Gerard S Conway , Anju Shukla , Mayuri Yeole , Periyasamy Radhakrishnan , Hatem Azzouz , Amel Ben Chehida , Monique Elmaleh-Bergès , Ruth I C Glasgow , Kyle Thompson , Monika Oláhová , Langping He , Emma M Jenkinson , Amir Jahic , Melanie Barzik , Jill E Urquhart , James O' Sullivan , Simon G Williams , Sanjeev S Bhaskar , Samantha Carrera , Alexander J M Blakes , Siddharth Banka , Wyatt W Yue , Jamie M Ellingford , Henry Houlden , Auteur inconnu , Kevin J Munro , Thomas B Friedman , Robert W Taylor , Holger Prokisch , Raymond T O'Keefe , William G Newman

Mouse Models of Human Pathogenic Variants of

Genes

Avec: Risa Tona , Ivan A Lopez , Cristina Fenollar-Ferrer , Rabia Faridi , Claudio Anselmi , Asma A Khan , Mohsin Shahzad , Robert J Morell , Shoujun Gu , Michael Hoa , Lijin Dong , Akira Ishiyama , Sheikh Riazuddin , Thomas B Friedman

ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points.

The Journal of cell biology

Avec: Jocelyn F Krey , Chang Liu , Michael Bateschell , Rachel A Dumont , Jennifer Goldsmith , Paroma Chatterjee , Rachel S Morrill , Lev M Fedorov , Sarah Foster , Jinkyung Kim , Alfred L Nuttall , Sherri M Jones , Dongseok Choi , Thomas B Friedman , Anthony J Ricci , Bo Zhao , Peter G Barr-Gillespie

Actin at stereocilia tips is regulated by mechanotransduction and ADF/cofilin.

Current biology : CB

Avec: Jamis McGrath , Chun-Yu Tung , Xiayi Liao , Pallabi Roy , Oisorjo Chakraborty , Jinan Li , Nicolas F Berbari , Christian C Faaborg-Andersen , Melanie Barzik , Jonathan E Bird , Bo Zhao , Lata Balakrishnan , Thomas B Friedman , Benjamin J Perrin

Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations.

American journal of human genetics

Avec: Irit Hochberg , Leigh A M Demain , Julie Richer , Kyle Thompson , Jill E Urquhart , Alessandro Rea , Waheeda Pagarkar , Agustí Rodríguez-Palmero , Agatha Schlüter , Edgard Verdura , Aurora Pujol , Pilar Quijada-Fraile , Albert Amberger , Andrea J Deutschmann , Sandra Demetz , Meredith Gillespie , Hugh J McMillan , Melanie Barzik , Glenda M Beaman , Reeya Motha , Kah Ying Ng , James O'Sullivan , Simon G Williams , Sanjeev S Bhaskar , Isabella R Lawrence , Emma M Jenkinson , Jessica L Zambonin , Zeev Blumenfeld , Sergey Yalonetsky , Stephanie Oerum , Walter Rossmanith , Auteur inconnu , Wyatt W Yue , Johannes Zschocke , Kevin J Munro , Brendan J Battersby , Thomas B Friedman , Robert W Taylor , Raymond T O'Keefe , William G Newman

Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants.

The Journal of biological chemistry

Avec: Risa Tona , Sayaka Inagaki , Yasuko Ishibashi , Rabia Faridi , Rizwan Yousaf , Isabelle Roux , Elizabeth Wilson , Cristina Fenollar-Ferrer , Wade W Chien , Thomas B Friedman

TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing.

JCI insight

Avec: Tatsuya Katsuno , Alexander X Cartagena-Rivera , Keisuke Ohta , Shawn M Crump , Ronald S Petralia , Kazuya Ono , Risa Tona , Ayesha Imtiaz , Atteeq Rehman , Hiroshi Kiyonari , Mari Kaneko , Ya-Xian Wang , Takaya Abe , Makoto Ikeya , Cristina Fenollar-Ferrer , Gavin P Riordan , Elisabeth A Wilson , Tracy S Fitzgerald , Kohei Segawa , Koichi Omori , Juichi Ito , Gregory I Frolenkov , Thomas B Friedman , Shin-Ichiro Kitajiri

The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy.

Human molecular genetics

Avec: Risa Tona , Wenqian Chen , Yoko Nakano , Laura D Reyes , Ronald S Petralia , Ya-Xian Wang , Matthew F Starost , Talah T Wafa , Robert J Morell , Kevin D Cravedi , Johann du Hoffmann , Takushi Miyoshi , Jeeva P Munasinghe , Tracy S Fitzgerald , Yogita Chudasama , Koichi Omori , Carlo Pierpaoli , Botond Banfi , Lijin Dong , Thomas B Friedman

Variants of human CLDN9 cause mild to profound hearing loss.

Human mutation

Avec: Memoona Ramzan , Christophe Philippe , Yoko Nakano , Cristina Fenollar-Ferrer , Risa Tona , Rizwan Yousaf , Rasheeda Basheer , Ayesha Imtiaz , Rabia Faridi , Zunaira Munir , Hafiza Idrees , Midhat Salman , Sophie Nambot , Antonio Vitobello , Souad Kartti , Oumaima Zarrik , P Dane Witmer , Nara Sobreria , Azeddine Ibrahimi , Botond Banfi , Sebastien Moutton , Thomas B Friedman , Sadaf Naz

Human deafness-associated variants alter the dynamics of key molecules in hair cell stereocilia F-actin cores.

Human genetics

Avec: Takushi Miyoshi , Shin-Ichiro Kitajiri , Hiroki Miyajima , Shin-Ya Nishio , Shin-Ichi Usami , Bong Jik Kim , Byung Yoon Choi , Koichi Omori , Hari Shroff , Thomas B Friedman

Myosins and Hearing.

Advances in experimental medicine and biology

Avec: Thomas B Friedman , Gregory I Frolenkov

Semi-automated single-molecule microscopy screening of fast-dissociating specific antibodies directly from hybridoma cultures.

Cell reports

Avec: Takushi Miyoshi , Qianli Zhang , Takafumi Miyake , Shin Watanabe , Hiroe Ohnishi , Jiji Chen , Harshad D Vishwasrao , Oisorjo Chakraborty , Benjamin J Perrin , Hari Shroff , Thomas B Friedman , Koichi Omori , Naoki Watanabe

Pathophysiology of human hearing loss associated with variants in myosins.

Frontiers in physiology

Avec: Takushi Miyoshi , Mrudhula Sajeevadathan , Thomas B Friedman

Unbalanced bidirectional radial stiffness gradients within the organ of Corti promoted by TRIOBP.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Hesam Babahosseini , Rizwan Yousaf , Risa Tona , Shadan Hadi , Sayaka Inagaki , Elizabeth Wilson , Shin-Ichiro Kitajiri , Gregory I Frolenkov , Thomas B Friedman , Alexander X Cartagena-Rivera

Dual-AAV vector-mediated expression of

Molecular therapy. Methods & clinical development

Avec: Samantha C Lau , Mhamed Grati , Kevin Isgrig , Moaz Sinan , Kaitlyn R Calabro , Jianliang Zhu , Yasuko Ishibashi , Zeynep Ozgur , Talah Wafa , Tracy Fitzgerald , Thomas B Friedman , Sanford L Boye , Shannon E Boye , Wade W Chien

Réseau de co-auteurs

Thomas B Friedman 17 collaborations

Risa Tona 6 collaborations

Takushi Miyoshi 5 collaborations

Cristina Fenollar-Ferrer 4 collaborations

Koichi Omori 4 collaborations

Alexander X Cartagena-Rivera 3 collaborations

Yasuko Ishibashi 3 collaborations

Hari Shroff 3 collaborations

Melanie Barzik 3 collaborations

Rabia Faridi 3 collaborations

Rizwan Yousaf 3 collaborations

Gregory I Frolenkov 3 collaborations

Shin-Ichiro Kitajiri 3 collaborations

Kevin Isgrig 2 collaborations

Mhamed Grati 2 collaborations

Harshad D Vishwasrao 2 collaborations

Mrudhula Sajeevadathan 2 collaborations

Leigh A M Demain 2 collaborations

Alessandro Rea 2 collaborations

Kyle Thompson 2 collaborations

Emma M Jenkinson 2 collaborations

Jill E Urquhart 2 collaborations

Simon G Williams 2 collaborations

Sanjeev S Bhaskar 2 collaborations

Wyatt W Yue 2 collaborations

None None 2 collaborations

Kevin J Munro 2 collaborations

Robert W Taylor 2 collaborations

Raymond T O'Keefe 2 collaborations

William G Newman 2 collaborations

Robert J Morell 2 collaborations

Lijin Dong 2 collaborations

Bo Zhao 2 collaborations

Oisorjo Chakraborty 2 collaborations

Benjamin J Perrin 2 collaborations

Sayaka Inagaki 2 collaborations

Elizabeth Wilson 2 collaborations

Wade W Chien 2 collaborations

Ronald S Petralia 2 collaborations

Ayesha Imtiaz 2 collaborations

Ya-Xian Wang 2 collaborations

Tracy S Fitzgerald 2 collaborations

Yoko Nakano 2 collaborations

Botond Banfi 2 collaborations

Hong Jun Wang 1 collaboration

Katharine A Fernandez 1 collaboration

Wade Chien 1 collaboration

Samuel M Adadey 1 collaboration

Narinobu Harada 1 collaboration

Thomas B Smith 1 collaboration

Robert Kopajtich 1 collaboration

Huw B Thomas 1 collaboration

Manuel Schiff 1 collaboration

Christian Beetz 1 collaboration

Shelagh Joss 1 collaboration

Gerard S Conway 1 collaboration

Anju Shukla 1 collaboration

Mayuri Yeole 1 collaboration

Periyasamy Radhakrishnan 1 collaboration

Hatem Azzouz 1 collaboration

Amel Ben Chehida 1 collaboration

Monique Elmaleh-Bergès 1 collaboration

Ruth I C Glasgow 1 collaboration

Monika Oláhová 1 collaboration

Langping He 1 collaboration

Amir Jahic 1 collaboration

James O' Sullivan 1 collaboration

Samantha Carrera 1 collaboration

Alexander J M Blakes 1 collaboration

Siddharth Banka 1 collaboration

Jamie M Ellingford 1 collaboration

Henry Houlden 1 collaboration

Holger Prokisch 1 collaboration

Ivan A Lopez 1 collaboration

Claudio Anselmi 1 collaboration

Asma A Khan 1 collaboration

Mohsin Shahzad 1 collaboration

Shoujun Gu 1 collaboration

Michael Hoa 1 collaboration

Akira Ishiyama 1 collaboration

Sheikh Riazuddin 1 collaboration

Jocelyn F Krey 1 collaboration

Chang Liu 1 collaboration

Michael Bateschell 1 collaboration

Rachel A Dumont 1 collaboration

Jennifer Goldsmith 1 collaboration

Paroma Chatterjee 1 collaboration

Rachel S Morrill 1 collaboration

Lev M Fedorov 1 collaboration

Sarah Foster 1 collaboration

Jinkyung Kim 1 collaboration

Alfred L Nuttall 1 collaboration

Sherri M Jones 1 collaboration

Dongseok Choi 1 collaboration

Anthony J Ricci 1 collaboration

Peter G Barr-Gillespie 1 collaboration

Jamis McGrath 1 collaboration

Chun-Yu Tung 1 collaboration

Xiayi Liao 1 collaboration

Pallabi Roy 1 collaboration

Jinan Li 1 collaboration

Nicolas F Berbari 1 collaboration

Christian C Faaborg-Andersen 1 collaboration

Jonathan E Bird 1 collaboration

Lata Balakrishnan 1 collaboration

Irit Hochberg 1 collaboration

Julie Richer 1 collaboration

Waheeda Pagarkar 1 collaboration

Agustí Rodríguez-Palmero 1 collaboration

Agatha Schlüter 1 collaboration

Edgard Verdura 1 collaboration

Aurora Pujol 1 collaboration

Pilar Quijada-Fraile 1 collaboration

Albert Amberger 1 collaboration

Andrea J Deutschmann 1 collaboration

Sandra Demetz 1 collaboration

Meredith Gillespie 1 collaboration

Hugh J McMillan 1 collaboration

Glenda M Beaman 1 collaboration

Reeya Motha 1 collaboration

Kah Ying Ng 1 collaboration

James O'Sullivan 1 collaboration

Isabella R Lawrence 1 collaboration

Jessica L Zambonin 1 collaboration

Zeev Blumenfeld 1 collaboration

Sergey Yalonetsky 1 collaboration

Stephanie Oerum 1 collaboration

Walter Rossmanith 1 collaboration

Johannes Zschocke 1 collaboration

Brendan J Battersby 1 collaboration

Isabelle Roux 1 collaboration

Tatsuya Katsuno 1 collaboration

Keisuke Ohta 1 collaboration

Shawn M Crump 1 collaboration

Kazuya Ono 1 collaboration

Atteeq Rehman 1 collaboration

Hiroshi Kiyonari 1 collaboration

Mari Kaneko 1 collaboration

Takaya Abe 1 collaboration

Makoto Ikeya 1 collaboration

Gavin P Riordan 1 collaboration

Elisabeth A Wilson 1 collaboration

Kohei Segawa 1 collaboration

Juichi Ito 1 collaboration

Wenqian Chen 1 collaboration

Laura D Reyes 1 collaboration

Matthew F Starost 1 collaboration

Talah T Wafa 1 collaboration

Kevin D Cravedi 1 collaboration

Johann du Hoffmann 1 collaboration

Jeeva P Munasinghe 1 collaboration

Yogita Chudasama 1 collaboration

Carlo Pierpaoli 1 collaboration

Memoona Ramzan 1 collaboration

Christophe Philippe 1 collaboration

Rasheeda Basheer 1 collaboration

Zunaira Munir 1 collaboration

Hafiza Idrees 1 collaboration

Midhat Salman 1 collaboration

Sophie Nambot 1 collaboration

Antonio Vitobello 1 collaboration

Souad Kartti 1 collaboration

Oumaima Zarrik 1 collaboration

P Dane Witmer 1 collaboration

Nara Sobreria 1 collaboration

Azeddine Ibrahimi 1 collaboration

Sebastien Moutton 1 collaboration

Sadaf Naz 1 collaboration

Hiroki Miyajima 1 collaboration

Shin-Ya Nishio 1 collaboration

Shin-Ichi Usami 1 collaboration

Bong Jik Kim 1 collaboration

Byung Yoon Choi 1 collaboration

Qianli Zhang 1 collaboration

Takafumi Miyake 1 collaboration

Shin Watanabe 1 collaboration

Hiroe Ohnishi 1 collaboration

Jiji Chen 1 collaboration

Naoki Watanabe 1 collaboration

Hesam Babahosseini 1 collaboration

Shadan Hadi 1 collaboration

Samantha C Lau 1 collaboration

Moaz Sinan 1 collaboration

Kaitlyn R Calabro 1 collaboration

Jianliang Zhu 1 collaboration

Zeynep Ozgur 1 collaboration

Talah Wafa 1 collaboration

Tracy Fitzgerald 1 collaboration

Sanford L Boye 1 collaboration

Shannon E Boye 1 collaboration