Ikechukwu Achilonu

Affiliations

Protein Structure-Function Research Unit, School of Molecular and Cell Biology, University of Witwatersrand, Johannesburg 2050, South Africa.

Publications (30)

Double trouble? Gag in conjunction with double insert in HIV protease contributes to reduced DRV susceptibility.

The Biochemical journal

Avec: Alison Williams , Adriaan Basson , Heini W Dirr , Lynn Morris , Yasien Sayed

Caseinolytic Proteins (Clp) in the Genus

Molecules (Basel, Switzerland)

Avec: Tehrim Motiwala , Blessing Oluebube Akumadu , Sbahle Zuma , Mbalenhle Sizamile Mfeka , Wanping Chen , Khajamohiddin Syed , Thandeka Khoza

Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase.

The protein journal

Avec: Tasvi Daya , Olamide Jeje , Reabetswe Maake , Chinyere Aloke , Thandeka Khoza ,

The future of cassava in the era of biotechnology in Southern Africa.

Critical reviews in biotechnology

Avec: Sarah Otun , Ainoa Escrich , Molemi Rauwane , Jordy Alexis Lerma-Escalera , José Rubén Morones-Ramírez , Leonardo Rios-Solis

Comparative Characterization of

Biomolecules

Avec: Charity Mekgwa Lebepe , Pearl Rutendo Matambanadzo , Xolani Henry Makhoba , Tawanda Zininga , Addmore Shonhai

Comparative structural analysis of the human and Schistosoma glutathione transferase dimer interface using selective binding of bromosulfophthalein.

Proteins

Avec: Akeel Valli ,

Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies.

International journal of biological macromolecules

Avec: Olamide Jeje , Ramesh Pandian , Yasien Sayed ,

Combating Lassa Fever in West African Sub-Region: Progress, Challenges, and Future Perspectives.

Viruses

Avec: Chinyere Aloke , Nwogo Ajuka Obasi , Patrick Maduabuchi Aja , Chinedum Uche Emelike , Chinedu Ogbonnia Egwu , Olamide Jeje , Chuks Oswald Edeogu , Olalekan Olugbenga Onisuru , Obasi Uche Orji ,

Molecular dynamics-derived pharmacophores of Schistosoma glutathione transferase in complex with bromosulfophthalein: Screening and analysis of potential inhibitors.

Journal of molecular graphics & modelling

Avec: Akeel Valli ,

Engineering a Pseudo-26-kDa

Biomolecules

Avec: Neo Padi , Blessing Oluebube Akumadu , Olga Faerch , Chinyere Aloke , Vanessa Meyer ,

SARS-CoV-2 Spike Protein Unlikely to Bind to Integrins

Frontiers in molecular biosciences

Avec: Houcemeddine Othman , Haifa Ben Messaoud , Oussema Khamessi , Hazem Ben-Mabrouk , Kais Ghedira , Avani Bharuthram , Florette Treurnicht , Yasien Sayed , Najet Srairi-Abid

Describing the ligandin properties of

Journal of biomolecular structure & dynamics

Avec: Olalekan Onisuru ,

Nuclear localisation sequences of chloride intracellular channels 1 and 4 facilitate nuclear import via interactions with import mediator importin-α: An empirical and theoretical perspective.

Journal of molecular recognition : JMR

Avec: Olga Faerch , Roland Worth , Heini Dirr

Exploiting Copaifera salikounda compounds as treatment against diabetes: An insight into their potential targets from a computational perspective.

Computational biology and chemistry

Avec: Chinyere Aloke , Emmanuel Amarachi Iwuchukwu ,

Unveiling the potential of Muscadine grape Skin extract as an innovative therapeutic intervention in cancer treatment.

Journal of functional foods

Avec: Sarah Otun , Valerie Odero-Marah

Expression, Purification and Biophysical Characterisation of Klebsiella Pneumoniae Protein Adenylyltransferase: A Systematic Integration of Empirical and Computational Modelling Approaches.

The protein journal

Avec: Reabetswe Maake ,

Drug susceptibility and replication capacity of a rare HIV-1 subtype C protease hinge region variant.

Antiviral therapy

Avec: Jake Zondagh , Adriaan E Basson , Lynn Morris , Heini W Dirr , Yasien Sayed

Effect of Divalent Metal Ion on the Structure, Stability and Function of

International journal of molecular sciences

Avec: Olamide Jeje , Reabetswe Maake , Ruan van Deventer , Veruschka Esau , Emmanuel Amarachi Iwuchukwu , Vanessa Meyer , Thandeka Khoza ,

Exploring NAD

Biochimie

Avec: Olamide Jeje , Sarah Otun , Chinyere Aloke ,

Biophysical description of Bromosulfophthalein interaction with the 28-kDa glutathione transferase from Schistosoma japonicum.

Molecular and biochemical parasitology

Avec: Kagiso Pooe , Monare Thulo , Hattie Makumbe , Blessing Akumadu , Oluwatobin Otun , Chinyere Aloke ,

Combating Aminoglycoside Resistance: From Structural and Functional Characterisation to Therapeutic Challenges with RKAAT.

Current protein & peptide science

Avec: Sarah Otun , Richard Graca

Contrasting the effect of hinge region insertions and non-active site mutations on HIV protease-inhibitor interactions: Insights from altered flap dynamics.

Journal of molecular graphics & modelling

Avec: Tshele Mokhantso , Dean Sherry , Roland Worth , Ramesh Pandian , Yasien Sayed

Glutathione S-transferase: A versatile and dynamic enzyme.

Biochemical and biophysical research communications

Avec: Chinyere Aloke , Olalekan Olugbenga Onisuru ,

Comparative analyses and structural insights of new class glutathione transferases in Cryptosporidium species.

Scientific reports

Avec: Mbalenhle Sizamile Mfeka , José Martínez-Oyanedel , Wanping Chen , Khajamohiddin Syed , Thandeka Khoza

Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2-P3 α-ketoamide derivative and Pentagastrin: An in-silico drug discovery approach.

Journal of molecular graphics & modelling

Avec: Emmanuel Amarachi Iwuchukwu , Okechinyere Juliet Achilonu , Manuel Antonio Fernandes , Yasien Sayed

Molecular basis of inhibition of Schistosoma japonicum glutathione transferase by ellagic acid: Insights into biophysical and structural studies.

Molecular and biochemical parasitology

Avec: Blessing O Akumadu , Ramesh Pandian , Jessica Olfsen , Roland Worth , Monare Thulo , Tshireletso Mentor , Sylvia Fanucchi , Yasien Sayed , Heini W Dirr ,

Exploring the evolutionary trajectory and functional landscape of cannabinoid receptors: A comprehensive bioinformatic analysis.

Computational biology and chemistry

Avec: Marushka Soobben , Yasien Sayed ,

ESKAPE Pathogens: Looking at Clp ATPases as Potential Drug Targets.

Antibiotics (Basel, Switzerland)

Avec: Tehrim Motiwala , Qiniso Mthethwa , Thandeka Khoza

Current Advances in the Management of Diabetes Mellitus.

Biomedicines

Avec: Chinyere Aloke , Chinedu Ogbonnia Egwu , Patrick Maduabuchi Aja , Nwogo Ajuka Obasi , Jennifer Chukwu , Blessing Oluebube Akumadu , Patience Nkemjika Ogbu ,

Coping with the ESKAPE pathogens: Evolving strategies, challenges and future prospects.

Microbial pathogenesis

Avec: Chinyere Aloke ,

Réseau de co-auteurs

Chinyere Aloke 9 collaborations

Yasien Sayed 8 collaborations

Thandeka Khoza 5 collaborations

Olamide Jeje 5 collaborations

Sarah Otun 4 collaborations

Heini W Dirr 3 collaborations

Blessing Oluebube Akumadu 3 collaborations

Reabetswe Maake 3 collaborations

Ramesh Pandian 3 collaborations

Roland Worth 3 collaborations

Emmanuel Amarachi Iwuchukwu 3 collaborations

Lynn Morris 2 collaborations

Tehrim Motiwala 2 collaborations

Mbalenhle Sizamile Mfeka 2 collaborations

Wanping Chen 2 collaborations

Khajamohiddin Syed 2 collaborations

Akeel Valli 2 collaborations

Nwogo Ajuka Obasi 2 collaborations

Patrick Maduabuchi Aja 2 collaborations

Chinedu Ogbonnia Egwu 2 collaborations

Olalekan Olugbenga Onisuru 2 collaborations

Olga Faerch 2 collaborations

Vanessa Meyer 2 collaborations

Monare Thulo 2 collaborations

Alison Williams 1 collaboration

Adriaan Basson 1 collaboration

Sbahle Zuma 1 collaboration

Tasvi Daya 1 collaboration

Ainoa Escrich 1 collaboration

Molemi Rauwane 1 collaboration

Jordy Alexis Lerma-Escalera 1 collaboration

José Rubén Morones-Ramírez 1 collaboration

Leonardo Rios-Solis 1 collaboration

Charity Mekgwa Lebepe 1 collaboration

Pearl Rutendo Matambanadzo 1 collaboration

Xolani Henry Makhoba 1 collaboration

Tawanda Zininga 1 collaboration

Addmore Shonhai 1 collaboration

Chinedum Uche Emelike 1 collaboration

Chuks Oswald Edeogu 1 collaboration

Obasi Uche Orji 1 collaboration

Neo Padi 1 collaboration

Houcemeddine Othman 1 collaboration

Haifa Ben Messaoud 1 collaboration

Oussema Khamessi 1 collaboration

Hazem Ben-Mabrouk 1 collaboration

Kais Ghedira 1 collaboration

Avani Bharuthram 1 collaboration

Florette Treurnicht 1 collaboration

Najet Srairi-Abid 1 collaboration

Olalekan Onisuru 1 collaboration

Heini Dirr 1 collaboration

Valerie Odero-Marah 1 collaboration

Jake Zondagh 1 collaboration

Adriaan E Basson 1 collaboration

Ruan van Deventer 1 collaboration

Veruschka Esau 1 collaboration

Kagiso Pooe 1 collaboration

Hattie Makumbe 1 collaboration

Blessing Akumadu 1 collaboration

Oluwatobin Otun 1 collaboration

Richard Graca 1 collaboration

Tshele Mokhantso 1 collaboration

Dean Sherry 1 collaboration

José Martínez-Oyanedel 1 collaboration

Okechinyere Juliet Achilonu 1 collaboration

Manuel Antonio Fernandes 1 collaboration

Blessing O Akumadu 1 collaboration

Jessica Olfsen 1 collaboration

Tshireletso Mentor 1 collaboration

Sylvia Fanucchi 1 collaboration

Marushka Soobben 1 collaboration

Qiniso Mthethwa 1 collaboration

Jennifer Chukwu 1 collaboration

Patience Nkemjika Ogbu 1 collaboration