Helen Poska

Affiliations

Department of Biosciences and Nutrition, Karolinska Institutet 141 52 Huddinge Sweden gefei.chen@ki.se.
School of Natural Sciences and Health, Tallinn University Tallinn Estonia.

ORCID: https://orcid.org/0000-0002-1346-4862

Publications (5)

Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue.

RSC chemical biology

Avec: Gefei Chen , Yuniesky Andrade-Talavera , Xueying Zhong , Sameer Hassan , Henrik Biverstål , Axel Abelein , Axel Leppert , Nina Kronqvist , Anna Rising , Hans Hebert , Philip J B Koeck , André Fisahn , Jan Johansson

Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation.

Molecular psychiatry

Avec: Gorka Gerenu , Torbjörn Persson , Julen Goikolea , Javier Calvo-Garrido , Raúl Loera-Valencia , Philipp Pottmeier , Cesar Santiago , Jenny Presto , Angel Cedazo-Minguez

Recombinant Bri3 BRICHOS domain is a molecular chaperone with effect against amyloid formation and non-fibrillar protein aggregation.

Scientific reports

Avec: Axel Leppert , Helene Tigro , Xueying Zhong , Margit Kaldmäe , Harriet E Nilsson , Hans Hebert , Gefei Chen , Jan Johansson

A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain.

Protein science : a publication of the Protein Society

Avec: Axel Leppert , Michael Landreh , Axel Abelein , Gefei Chen , Jan Johansson

Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation.

Communications biology

Avec: Gefei Chen , Axel Leppert , Harriet E Nilsson , Carlos Piedrafita Alvira , Xueying Zhong , Philip Koeck , Caroline Jegerschöld , Axel Abelein , Hans Hebert , Jan Johansson

Réseau de co-auteurs

Gefei Chen 4 collaborations

Axel Leppert 4 collaborations

Jan Johansson 4 collaborations

Xueying Zhong 3 collaborations

Axel Abelein 3 collaborations

Hans Hebert 3 collaborations

Harriet E Nilsson 2 collaborations

Yuniesky Andrade-Talavera 1 collaboration

Sameer Hassan 1 collaboration

Henrik Biverstål 1 collaboration

Nina Kronqvist 1 collaboration

Anna Rising 1 collaboration

Philip J B Koeck 1 collaboration

André Fisahn 1 collaboration

Gorka Gerenu 1 collaboration

Torbjörn Persson 1 collaboration

Julen Goikolea 1 collaboration

Javier Calvo-Garrido 1 collaboration

Raúl Loera-Valencia 1 collaboration

Philipp Pottmeier 1 collaboration

Cesar Santiago 1 collaboration

Jenny Presto 1 collaboration

Angel Cedazo-Minguez 1 collaboration

Helene Tigro 1 collaboration

Margit Kaldmäe 1 collaboration

Michael Landreh 1 collaboration

Carlos Piedrafita Alvira 1 collaboration

Philip Koeck 1 collaboration

Caroline Jegerschöld 1 collaboration