Guendalina Froechlich

Affiliations

CEINGE-Biotecnologie Avanzate S.C. aR.L., via Gaetano Salvatore 486, 80145 Naples, Italy.
Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131 Napoli, Italy.

Publications (14)

Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment.

Molecular therapy oncolytics

Avec: Maria De Lucia , Gabriella Cotugno , Veronica Bignone , Irene Garzia , Linda Nocchi , Francesca Langone , Biljana Petrovic , Emanuele Sasso , Simona Pepe , Chiara Gentile , Nicola Zambrano , Gabriella Campadelli-Fiume , Alfredo Nicosia , Elisa Scarselli , Anna Morena D'Alise

Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments.

Cancers

Avec: Cinzia Vetrei , Margherita Passariello , Rosa Rapuano Lembo , Nicola Zambrano , Claudia De Lorenzo

Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis.

Scientific reports

Avec: Emanuele Sasso , Gabriella Cotugno , Anna Morena D'Alise , Chiara Gentile , Veronica Bignone , Maria De Lucia , Biljana Petrovic , Gabriella Campadelli-Fiume , Elisa Scarselli , Alfredo Nicosia , Nicola Zambrano

The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant possesses wild-type properties.

Scientific reports

Avec: Arianna Finizio , Alessandra Napolano , Sara Amiranda , Arianna De Chiara , Pasqualina Pagano , Massimo Mallardo , Guido Leoni , Nicola Zambrano , Emanuele Sasso

Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells.

Cancers

Avec: Margherita Passariello , Cinzia Vetrei , Emanuele Sasso , Chiara Gentile , Anna Morena D'Alise , Nicola Zambrano , Elisa Scarselli , Alfredo Nicosia , Claudia De Lorenzo

Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of

Cancers

Avec: Carmen Caiazza , Chiara Gentile , Anna Morena D'Alise , Maria De Lucia , Francesca Langone , Guido Leoni , Gabriella Cotugno , Vittorio Scisciola , Alfredo Nicosia , Elisa Scarselli , Massimo Mallardo , Emanuele Sasso , Nicola Zambrano

Generation of a Retargeted Oncolytic

International journal of molecular sciences

Avec: Chiara Gentile , Arianna Finizio , Anna Morena D'Alise , Gabriella Cotugno , Sara Amiranda , Alfredo Nicosia , Elisa Scarselli , Nicola Zambrano , Emanuele Sasso

Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling.

Scientific reports

Avec: Margherita Passariello , Anna Morena D'Alise , Annachiara Esposito , Cinzia Vetrei , Elisa Scarselli , Alfredo Nicosia , Claudia De Lorenzo

Novel Combinations of Human Immunomodulatory mAbs Lacking Cardiotoxic Effects for Therapy of TNBC.

Cancers

Avec: Cinzia Vetrei , Margherita Passariello , Rosa Rapuano Lembo , Emanuele Sasso , Nicola Zambrano , Claudia De Lorenzo

New Insights on the Role of Anti-PD-L1 and Anti-CTLA-4 mAbs on Different Lymphocytes Subpopulations in TNBC.

Cancers

Avec: Rosa Rapuano Lembo , Lorenzo Manna , Emanuele Sasso , Margherita Passariello , Claudia De Lorenzo

Generation of a Novel Mesothelin-Targeted Oncolytic

International journal of molecular sciences

Avec: Chiara Gentile , Luigia Infante , Carmen Caiazza , Pasqualina Pagano , Sarah Scatigna , Gabriella Cotugno , Anna Morena D'Alise , Armin Lahm , Elisa Scarselli , Alfredo Nicosia , Massimo Mallardo , Emanuele Sasso , Nicola Zambrano

High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand.

Cancers

Avec: Nicola Zambrano , Dejan Lazarevic , Margherita Passariello , Alfredo Nicosia , Claudia De Lorenzo , Marco J Morelli , Emanuele Sasso

Prime and pull of T cell responses against cancer-exogenous antigens is effective against CPI-resistant tumors.

Molecular therapy. Oncology

Avec: Fulvia Troise , Guido Leoni , Emanuele Sasso , Mariarosaria Del Sorbo , Marialuisa Esposito , Giuseppina Romano , Simona Allocca , Gabriella Cotugno , Stefania Capone , Antonella Folgori , Elisa Scarselli , Anna Morena D'Alise , Alfredo Nicosia

Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus.

Cancer gene therapy

Avec: A Finizio , P Pagano , A Napolano , G Froechlich , L Infante , A De Chiara , S Amiranda , E Vitiello , S Totaro , C Capasso , M Raia , A M D'Alise , P de Candia , N Zambrano , E Sasso

Réseau de co-auteurs

Emanuele Sasso 11 collaborations

Nicola Zambrano 10 collaborations

Alfredo Nicosia 9 collaborations

Elisa Scarselli 8 collaborations

Anna Morena D'Alise 8 collaborations

Gabriella Cotugno 6 collaborations

Chiara Gentile 6 collaborations

Margherita Passariello 6 collaborations

Claudia De Lorenzo 6 collaborations

Cinzia Vetrei 4 collaborations

Maria De Lucia 3 collaborations

Rosa Rapuano Lembo 3 collaborations

Massimo Mallardo 3 collaborations

Guido Leoni 3 collaborations

Veronica Bignone 2 collaborations

Francesca Langone 2 collaborations

Biljana Petrovic 2 collaborations

Gabriella Campadelli-Fiume 2 collaborations

Arianna Finizio 2 collaborations

Sara Amiranda 2 collaborations

Pasqualina Pagano 2 collaborations

Carmen Caiazza 2 collaborations

Irene Garzia 1 collaboration

Linda Nocchi 1 collaboration

Simona Pepe 1 collaboration

Alessandra Napolano 1 collaboration

Arianna De Chiara 1 collaboration

Vittorio Scisciola 1 collaboration

Annachiara Esposito 1 collaboration

Lorenzo Manna 1 collaboration

Luigia Infante 1 collaboration

Sarah Scatigna 1 collaboration

Armin Lahm 1 collaboration

Dejan Lazarevic 1 collaboration

Marco J Morelli 1 collaboration

Fulvia Troise 1 collaboration

Mariarosaria Del Sorbo 1 collaboration

Marialuisa Esposito 1 collaboration

Giuseppina Romano 1 collaboration

Simona Allocca 1 collaboration

Stefania Capone 1 collaboration

Antonella Folgori 1 collaboration

A Finizio 1 collaboration

P Pagano 1 collaboration

A Napolano 1 collaboration

G Froechlich 1 collaboration

L Infante 1 collaboration

A De Chiara 1 collaboration

S Amiranda 1 collaboration

E Vitiello 1 collaboration

S Totaro 1 collaboration

C Capasso 1 collaboration

M Raia 1 collaboration

A M D'Alise 1 collaboration

P de Candia 1 collaboration

N Zambrano 1 collaboration

E Sasso 1 collaboration