Ghaith Aljayyoussi

Affiliations

Research Centre for Drugs and Diagnostics, Department of Parasitology, Liverpool School of Tropical Medicine, L3 5QA Liverpool, United Kingdom.

Publications (22)

AWZ1066S, a highly specific anti-

Proceedings of the National Academy of Sciences of the United States of America

Avec: W David Hong , Farid Benayoud , Gemma L Nixon , Louise Ford , Kelly L Johnston , Rachel H Clare , Andrew Cassidy , Darren A N Cook , Amy Siu , Motohiro Shiotani , Peter J H Webborn , Stefan Kavanagh , Emma Murphy , Andrew Steven , John Archer , Dominique Struever , Stefan J Frohberger , Alexandra Ehrens , Marc P Hübner , Achim Hoerauf , Adam P Roberts , Alasdair T M Hubbard , Edward W Tate , Remigiusz A Serwa , Suet C Leung , Li Qie , Neil G Berry , Fabian Gusovsky , Janet Hemingway , Joseph D Turner , Mark J Taylor , Stephen A Ward , Paul M O'Neill

Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose-Response Relationship Using Intracellular Pharmacodynamic Modeling (PD

Methods in molecular biology (Clifton, N.J.)

Avec: Samantha Donnellan , Carmen Martínez-Rodríguez , Giancarlo A Biagini

Human Direct Skin Feeding Versus Membrane Feeding to Assess the Mosquitocidal Efficacy of High-Dose Ivermectin (IVERMAL Trial).

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Menno R Smit , Eric O Ochomo , Titus K Kwambai , Bernard O Abong'o , Teun Bousema , David Waterhouse , Nabie M Bayoh , John E Gimnig , Aaron M Samuels , Meghna R Desai , Penelope A Phillips-Howard , Simon K Kariuki , Duolao Wang , Stephen A Ward , Feiko O Ter Kuile

Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.

British journal of clinical pharmacology

Avec: Rajith K R Rajoli , Henry Pertinez , Usman Arshad , Helen Box , Lee Tatham , Paul Curley , Megan Neary , Joanne Sharp , Neill J Liptrott , Anthony Valentijn , Christopher David , Steven P Rannard , Shaun H Pennington , Andrew Hill , Marta Boffito , Steve A Ward , Saye H Khoo , Patrick G Bray , Paul M O'Neill , W David Hong , Giancarlo A Biagini , Andrew Owen

Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.

Frontiers in immunology

Avec: Matthias J Düchs , Ramona F Kratzer , Pablo Vieyra-Garcia , Benjamin Strobel , Tanja Schönberger , Peter Groß , Aradhana Gupta , Isabel Lang , Holger Klein , Sandra Martinez Morilla , Stefan Hopf , John Park , Sebastian Kreuz , Matthias Klugmann , Frederik H Igney

Intracellular PD Modelling (

Pharmaceutics

Avec: Samantha Donnellan , Stephen A Ward , Giancarlo A Biagini

Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?

ACS infectious diseases

Avec: Andrew V Stachulski , Joshua Taujanskas , Sophie L Pate , Rajith K R Rajoli , Shaun H Pennington , Stephen A Ward , Weiqian David Hong , Giancarlo A Biagini , Andrew Owen , Gemma L Nixon , Suet C Leung , Paul M O'Neill

SARS-CoV-2 viability on sports equipment is limited, and dependent on material composition.

Scientific reports

Avec: Thomas Edwards , Grant A Kay , Sophie I Owen , Andy R Harland , Nicholas S Pierce , James D F Calder , Tom E Fletcher , Emily R Adams

Combinations of the azaquinazoline anti-

Frontiers in microbiology

Avec: Shrilakshmi Hegde , Amy E Marriott , Nicolas Pionnier , Andrew Steven , Christina Bulman , Emma Gunderson , Ian Vogel , Marianne Koschel , Alexandra Ehrens , Sara Lustigman , Denis Voronin , Nancy Tricoche , Achim Hoerauf , Marc P Hübner , Judy Sakanari , Fabian Gusovsky , Jessica Dagley , David W Hong , Paul O'Neill , Steven A Ward , Mark J Taylor , Joseph D Turner

Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infection Model.

PLoS neglected tropical diseases

Avec: Celina Jin , Malick M Gibani , Shaun H Pennington , Xinxue Liu , Alison Ardrey , Maria Moore , Brian Angus , Christopher M Parry , Giancarlo A Biagini , Nicholas A Feasey , Andrew J Pollard

Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.

medRxiv : the preprint server for health sciences

Avec: Rajith Kr Rajoli , Henry Pertinez , Usman Arshad , Helen Box , Lee Tatham , Paul Curley , Megan Neary , Joanne Sharp , Neill J Liptrott , Anthony Valentijn , Christopher David , Steve P Rannard , Shaun H Pennington , Andrew Hill , Marta Boffito , Stephen A Ward , Saye H Khoo , Patrick G Bray , Paul M O'Neill , W Dave Hong , Giancarlo Biagini , Andrew Owen

Auto-fluorescent PAMAM-based dendritic molecules and their potential application in pharmaceutical sciences.

International journal of pharmaceutics

Avec: Alaa M M El-Betany , Elbadawy A Kamoun , Craig James , Abdulhakim Jangher , Peter Griffiths , Neil B McKeown , Mark Gumbleton

Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine.

Malaria journal

Avec: André Daher , Ghait Aljayyoussi , Dhelio Pereira , Marcus V G Lacerda , Márcia A A Alexandre , Cristiana T Nascimento , Júlio Castro Alves , Laís Bastos da Fonseca , Diego Medeiros Dias da Silva , Douglas Pereira Pinto , Danielle Fonseca Rodrigues , Ana Carolina Rios Silvino , Taís Nóbrega de Sousa , Cristiana Ferreira Alves de Brito , Feiko O Ter Kuile , David G Lalloo

Intracellular Pharmacodynamic Modeling Is Predictive of the Clinical Activity of Fluoroquinolones against Tuberculosis.

Antimicrobial agents and chemotherapy

Avec: Samantha Donnellan , Emmanuel Moyo , Alison Ardrey , Carmen Martinez-Rodriguez , Stephen A Ward , Giancarlo A Biagini

Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2.

International journal of antimicrobial agents

Avec: Laura N Jeffreys , Shaun H Pennington , Jack Duggan , Claire H Caygill , Rose C Lopeman , Alastair F Breen , Jessica B Jinks , Alison Ardrey , Samantha Donnellan , Edward I Patterson , Grant L Hughes , David W Hong , Paul M O'Neill , Andrew Owen , Stephen A Ward , Giancarlo A Biagini

Preclinical development of an oral anti-

Science translational medicine

Avec: Mark J Taylor , Thomas W von Geldern , Louise Ford , Marc P Hübner , Kennan Marsh , Kelly L Johnston , Hanna T Sjoberg , Sabine Specht , Nicolas Pionnier , Hayley E Tyrer , Rachel H Clare , Darren A N Cook , Emma Murphy , Andrew Steven , John Archer , Dominique Bloemker , Franziska Lenz , Marianne Koschel , Alexandra Ehrens , Haelly M Metuge , Valerinne C Chunda , Patrick W Ndongmo Chounna , Abdel J Njouendou , Fanny F Fombad , Robert Carr , Howard E Morton , Achim Hoerauf , Samuel Wanji , Dale J Kempf , Joseph D Turner , Stephen A Ward

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models.

PLoS neglected tropical diseases

Avec: Hanna T Sjoberg , Nicolas Pionnier , Haelly M Metuge , Abdel J Njouendou , Valerine C Chunda , Fanny F Fombad , Dizzle B Tayong , Narcisse V T Gandjui , Desmond N Akumtoh , Patrick W N Chounna , Bertrand L Ndzeshang , Sophie Lachaud , Fetene Tekle , Ludo Quirynen , Marc Engelen , Benny Baeten , Andrew Steven , Stephen A Ward , Mark J Taylor , Samuel Wanji , Joseph D Turner

Pharmacokinetics-Pharmacodynamics of High-Dose Ivermectin with Dihydroartemisinin-Piperaquine on Mosquitocidal Activity and QT-Prolongation (IVERMAL).

Clinical pharmacology and therapeutics

Avec: Menno R Smit , Eric O Ochomo , David Waterhouse , Titus K Kwambai , Bernard O Abong'o , Teun Bousema , Nabie M Bayoh , John E Gimnig , Aaron M Samuels , Meghna R Desai , Penelope A Phillips-Howard , Simon K Kariuki , Duolao Wang , Feiko O Ter Kuile , Stephen A Ward ,

Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study.

The Lancet. Infectious diseases

Avec: Hannah C Slater , Brian D Foy , Kevin Kobylinski , Carlos Chaccour , Oliver J Watson , Joel Hellewell , Teun Bousema , Jeremy Burrows , Umberto D'Alessandro , Haoues Alout , Feiko O Ter Kuile , Patrick G T Walker , Azra C Ghani , Menno R Smit

Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.

Clinical pharmacology and therapeutics

Avec: Usman Arshad , Henry Pertinez , Helen Box , Lee Tatham , Rajith K R Rajoli , Paul Curley , Megan Neary , Joanne Sharp , Neill J Liptrott , Anthony Valentijn , Christopher David , Steve P Rannard , Paul M O'Neill , Shaun H Pennington , Stephen A Ward , Andrew Hill , David J Back , Saye H Khoo , Patrick G Bray , Giancarlo A Biagini , Andrew Owen

Saliva Alternative to Upper Respiratory Swabs for SARS-CoV-2 Diagnosis.

Emerging infectious diseases

Avec: Rachel L Byrne , Grant A Kay , Konstantina Kontogianni , Lottie Brown , Andrea M Collins , Luis E Cuevas , Daniela M Ferreira , Alice J Fraser , Gala Garrod , Helen Hill , Grant L Hughes , Stefanie Menzies , Elena Mitsi , Sophie I Owen , Edward I Patterson , Christopher T Williams , Angela Hyder-Wright , Emily R Adams , Ana I Cubas-Atienzar

The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of

Pharmaceuticals (Basel, Switzerland)

Avec: Annabelle Walz , Maëlle Duffey , Sibylle Sax , Didier Leroy , Dominique Besson , Jeremy N Burrows , Mohammed H Cherkaoui-Rbati , Nathalie Gobeau , Marie-Anne Westwood , Christoph Siethoff , Francisco-Javier Gamo , Pascal Mäser , Sergio Wittlin

Réseau de co-auteurs

Stephen A Ward 11 collaborations

Giancarlo A Biagini 8 collaborations

Paul M O'Neill 6 collaborations

Shaun H Pennington 6 collaborations

Andrew Owen 5 collaborations

Andrew Steven 4 collaborations

Joseph D Turner 4 collaborations

Mark J Taylor 4 collaborations

Samantha Donnellan 4 collaborations

Feiko O Ter Kuile 4 collaborations

Alexandra Ehrens 3 collaborations

Marc P Hübner 3 collaborations

Achim Hoerauf 3 collaborations

Menno R Smit 3 collaborations

Teun Bousema 3 collaborations

Rajith K R Rajoli 3 collaborations

Henry Pertinez 3 collaborations

Usman Arshad 3 collaborations

Helen Box 3 collaborations

Lee Tatham 3 collaborations

Paul Curley 3 collaborations

Megan Neary 3 collaborations

Joanne Sharp 3 collaborations

Neill J Liptrott 3 collaborations

Anthony Valentijn 3 collaborations

Christopher David 3 collaborations

Andrew Hill 3 collaborations

Saye H Khoo 3 collaborations

Patrick G Bray 3 collaborations

Nicolas Pionnier 3 collaborations

Alison Ardrey 3 collaborations

W David Hong 2 collaborations

Gemma L Nixon 2 collaborations

Louise Ford 2 collaborations

Kelly L Johnston 2 collaborations

Rachel H Clare 2 collaborations

Darren A N Cook 2 collaborations

Emma Murphy 2 collaborations

John Archer 2 collaborations

Suet C Leung 2 collaborations

Fabian Gusovsky 2 collaborations

Eric O Ochomo 2 collaborations

Titus K Kwambai 2 collaborations

Bernard O Abong'o 2 collaborations

David Waterhouse 2 collaborations

Nabie M Bayoh 2 collaborations

John E Gimnig 2 collaborations

Aaron M Samuels 2 collaborations

Meghna R Desai 2 collaborations

Penelope A Phillips-Howard 2 collaborations

Simon K Kariuki 2 collaborations

Duolao Wang 2 collaborations

Marta Boffito 2 collaborations

Grant A Kay 2 collaborations

Sophie I Owen 2 collaborations

Emily R Adams 2 collaborations

Marianne Koschel 2 collaborations

David W Hong 2 collaborations

Steve P Rannard 2 collaborations

Edward I Patterson 2 collaborations

Grant L Hughes 2 collaborations

Hanna T Sjoberg 2 collaborations

Haelly M Metuge 2 collaborations

Abdel J Njouendou 2 collaborations

Fanny F Fombad 2 collaborations

Samuel Wanji 2 collaborations

Farid Benayoud 1 collaboration

Andrew Cassidy 1 collaboration

Amy Siu 1 collaboration

Motohiro Shiotani 1 collaboration

Peter J H Webborn 1 collaboration

Stefan Kavanagh 1 collaboration

Dominique Struever 1 collaboration

Stefan J Frohberger 1 collaboration

Adam P Roberts 1 collaboration

Alasdair T M Hubbard 1 collaboration

Edward W Tate 1 collaboration

Remigiusz A Serwa 1 collaboration

Li Qie 1 collaboration

Neil G Berry 1 collaboration

Janet Hemingway 1 collaboration

Carmen Martínez-Rodríguez 1 collaboration

Steven P Rannard 1 collaboration

Steve A Ward 1 collaboration

Matthias J Düchs 1 collaboration

Ramona F Kratzer 1 collaboration

Pablo Vieyra-Garcia 1 collaboration

Benjamin Strobel 1 collaboration

Tanja Schönberger 1 collaboration

Peter Groß 1 collaboration

Aradhana Gupta 1 collaboration

Isabel Lang 1 collaboration

Holger Klein 1 collaboration

Sandra Martinez Morilla 1 collaboration

Stefan Hopf 1 collaboration

John Park 1 collaboration

Sebastian Kreuz 1 collaboration

Matthias Klugmann 1 collaboration

Frederik H Igney 1 collaboration

Andrew V Stachulski 1 collaboration

Joshua Taujanskas 1 collaboration

Sophie L Pate 1 collaboration

Weiqian David Hong 1 collaboration

Thomas Edwards 1 collaboration

Andy R Harland 1 collaboration

Nicholas S Pierce 1 collaboration

James D F Calder 1 collaboration

Tom E Fletcher 1 collaboration

Shrilakshmi Hegde 1 collaboration

Amy E Marriott 1 collaboration

Christina Bulman 1 collaboration

Emma Gunderson 1 collaboration

Ian Vogel 1 collaboration

Sara Lustigman 1 collaboration

Denis Voronin 1 collaboration

Nancy Tricoche 1 collaboration

Judy Sakanari 1 collaboration

Jessica Dagley 1 collaboration

Paul O'Neill 1 collaboration

Steven A Ward 1 collaboration

Celina Jin 1 collaboration

Malick M Gibani 1 collaboration

Xinxue Liu 1 collaboration

Maria Moore 1 collaboration

Brian Angus 1 collaboration

Christopher M Parry 1 collaboration

Nicholas A Feasey 1 collaboration

Andrew J Pollard 1 collaboration

Rajith Kr Rajoli 1 collaboration

W Dave Hong 1 collaboration

Giancarlo Biagini 1 collaboration

Alaa M M El-Betany 1 collaboration

Elbadawy A Kamoun 1 collaboration

Craig James 1 collaboration

Abdulhakim Jangher 1 collaboration

Peter Griffiths 1 collaboration

Neil B McKeown 1 collaboration

Mark Gumbleton 1 collaboration

André Daher 1 collaboration

Ghait Aljayyoussi 1 collaboration

Dhelio Pereira 1 collaboration

Marcus V G Lacerda 1 collaboration

Márcia A A Alexandre 1 collaboration

Cristiana T Nascimento 1 collaboration

Júlio Castro Alves 1 collaboration

Laís Bastos da Fonseca 1 collaboration

Diego Medeiros Dias da Silva 1 collaboration

Douglas Pereira Pinto 1 collaboration

Danielle Fonseca Rodrigues 1 collaboration

Ana Carolina Rios Silvino 1 collaboration

Taís Nóbrega de Sousa 1 collaboration

Cristiana Ferreira Alves de Brito 1 collaboration

David G Lalloo 1 collaboration

Emmanuel Moyo 1 collaboration

Carmen Martinez-Rodriguez 1 collaboration

Laura N Jeffreys 1 collaboration

Jack Duggan 1 collaboration

Claire H Caygill 1 collaboration

Rose C Lopeman 1 collaboration

Alastair F Breen 1 collaboration

Jessica B Jinks 1 collaboration

Thomas W von Geldern 1 collaboration

Kennan Marsh 1 collaboration

Sabine Specht 1 collaboration

Hayley E Tyrer 1 collaboration

Dominique Bloemker 1 collaboration

Franziska Lenz 1 collaboration

Valerinne C Chunda 1 collaboration

Patrick W Ndongmo Chounna 1 collaboration

Robert Carr 1 collaboration

Howard E Morton 1 collaboration

Dale J Kempf 1 collaboration

Valerine C Chunda 1 collaboration

Dizzle B Tayong 1 collaboration

Narcisse V T Gandjui 1 collaboration

Desmond N Akumtoh 1 collaboration

Patrick W N Chounna 1 collaboration

Bertrand L Ndzeshang 1 collaboration

Sophie Lachaud 1 collaboration

Fetene Tekle 1 collaboration

Ludo Quirynen 1 collaboration

Marc Engelen 1 collaboration

Benny Baeten 1 collaboration

Hannah C Slater 1 collaboration

Brian D Foy 1 collaboration

Kevin Kobylinski 1 collaboration

Carlos Chaccour 1 collaboration

Oliver J Watson 1 collaboration

Joel Hellewell 1 collaboration

Jeremy Burrows 1 collaboration

Umberto D'Alessandro 1 collaboration

Haoues Alout 1 collaboration

Patrick G T Walker 1 collaboration

Azra C Ghani 1 collaboration

David J Back 1 collaboration

Rachel L Byrne 1 collaboration

Konstantina Kontogianni 1 collaboration

Lottie Brown 1 collaboration

Andrea M Collins 1 collaboration

Luis E Cuevas 1 collaboration

Daniela M Ferreira 1 collaboration

Alice J Fraser 1 collaboration

Gala Garrod 1 collaboration

Helen Hill 1 collaboration

Stefanie Menzies 1 collaboration

Elena Mitsi 1 collaboration

Christopher T Williams 1 collaboration

Angela Hyder-Wright 1 collaboration

Ana I Cubas-Atienzar 1 collaboration

Annabelle Walz 1 collaboration

Maëlle Duffey 1 collaboration

Sibylle Sax 1 collaboration

Didier Leroy 1 collaboration

Dominique Besson 1 collaboration

Jeremy N Burrows 1 collaboration

Mohammed H Cherkaoui-Rbati 1 collaboration

Nathalie Gobeau 1 collaboration

Marie-Anne Westwood 1 collaboration

Christoph Siethoff 1 collaboration

Francisco-Javier Gamo 1 collaboration

Pascal Mäser 1 collaboration

Sergio Wittlin 1 collaboration