Gerald W Zamponi

Affiliations

Department of Physiology and Pharmacology Hotchkiss Brain Institute, Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. zamponi@ucalgary.ca.

ORCID: 0000-0002-0644-9066

Publications (46)

Cav3.2 T-type calcium channels control acute itch in mice.

Molecular brain

Avec: Vinicius M Gadotti , Joanna M Kreitinger , Nicholas B Wageling , Dylan Budke , Philippe Diaz ,

Dopamine Inputs from the Ventral Tegmental Area into the Medial Prefrontal Cortex Modulate Neuropathic Pain-Associated Behaviors in Mice.

Cell reports

Avec: Shuo Huang , Zizhen Zhang , Eder Gambeta , Shi Chen Xu , Catherine Thomas , Nathan Godfrey , Lina Chen , Said M'Dahoma , Stephanie L Borgland ,

TNF-α mediated upregulation of Na

Molecular brain

Avec: Flávio Henrique Pequeno de Macedo , Rosária Dias Aires , Esdras Guedes Fonseca , Renata Cristina Mendes Ferreira , Daniel Portela Dias Machado , Lina Chen , Fang-Xiong Zhang , Ivana A Souza , Virgínia Soares Lemos , Thiago Roberto Lima Romero , Aubin Moutal , Rajesh Khanna , Jader S Cruz

A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Ca

Molecular brain

Avec: Robin N Stringer , Bohumila Jurkovicova-Tarabova , Sun Huang , Omid Haji-Ghassemi , Romane Idoux , Anna Liashenko , Ivana A Souza , Yuriy Rzhepetskyy , Lubica Lacinova , Filip Van Petegem , Roger Pamphlett , Norbert Weiss

Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels.

Bioorganic chemistry

Avec: Hande Aygün Cevher , David Schaller , Maria A Gandini , Ozan Kaplan , Eder Gambeta , Fang Xiong Zhang , Mustafa Çelebier , Muhammad Nawaz Tahir , Gerhard Wolber , Miyase Gözde Gündüz

SUMOylation regulates USP5-Cav3.2 calcium channel interactions.

Molecular brain

Avec: Agustin Garcia-Caballero , Fang-Xiong Zhang , Lina Chen , Said M'Dahoma , Junting Huang ,

Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC.

Molecular brain

Avec: Agustin Garcia-Caballero , Maria A Gandini , Shuo Huang , Lina Chen , Ivana A Souza , Yan L Dang , M Jackson Stutts ,

A neuronal circuit for activating descending modulation of neuropathic pain.

Nature neuroscience

Avec: Junting Huang , Vinicius M Gadotti , Lina Chen , Ivana A Souza , Shuo Huang , Decheng Wang , Charu Ramakrishnan , Karl Deisseroth , Zizhen Zhang ,

Dopaminergic modulation of pain signals in the medial prefrontal cortex: Challenges and perspectives.

Neuroscience letters

Avec: Shuo Huang , Stephanie L Borgland ,

Ethosuximide inhibits acute histamine- and chloroquine-induced scratching behavior in mice.

Molecular brain

Avec: Vinicius M Gadotti ,

The life cycle of voltage-gated Ca

Neuronal signaling

Avec: Laurent Ferron , Saloni Koshti ,

Protocol for detecting plastic changes in defined neuronal populations in neuropathic mice.

STAR protocols

Avec: Zizhen Zhang ,

A Synthetically Accessible Small-Molecule Inhibitor of USP5-Cav3.2 Calcium Channel Interactions with Analgesic Properties.

ACS chemical neuroscience

Avec: Agustin Garcia-Caballero , Vinicius M Gadotti , Md Yousof Ali , Chris Bladen , Eder Gambeta , Jeffrey F Van Humbeck , Justin L MacCallum ,

Electrophysiological and computational analysis of Ca

Molecular brain

Avec: Emilio R Mustafá , Eder Gambeta , Robin N Stringer , Ivana A Souza , Norbert Weiss

RAR-alpha: Creator, protector, and tormentor.

Neuron

Avec: Erika K Harding , Laurent Ferron ,

A next generation peripherally restricted Cavα2δ-1 ligand with inhibitory action on Cav2.2 channels and utility in neuropathic pain.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Franz Kricek , Christine Ruf , Premji Meghani , Ivana A Souza , Maria A Gandini , George Skouteris

Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry.

Nature communications

Avec: Charlie H T Kwok , Erika K Harding , Nicole E Burma , Tamara Markovic , Nicolas Massaly , Nynke J van den Hoogen , Sierra Stokes-Heck , Eder Gambeta , Kristina Komarek , Hye Jean Yoon , Kathleen E Navis , Brendan B McAllister , Julia Canet-Pons , Churmy Fan , Rebecca Dalgarno , Evgueni Gorobets , James W Papatzimas , Zizhen Zhang , Yuta Kohro , Connor L Anderson , Roger J Thompson , Darren J Derksen , Jose A Morón , Tuan Trang

Development of Tetrahydroquinoline-Based Inhibitors for Chronic Pain.

ACS chemical neuroscience

Avec: Ketul V Patel , Vinicius M Gadotti , Agustin Garcia-Caballero , Flavia T T Antunes , Md Yousof Ali , Darren J Derksen

FMRP(1-297)-tat restores ion channel and synaptic function in a model of Fragile X syndrome.

Nature communications

Avec: Xiaoqin Zhan , Hadhimulya Asmara , Ning Cheng , Giriraj Sahu , Eduardo Sanchez , Fang-Xiong Zhang , Jong M Rho , Ray W Turner

Acute orofacial pain leads to prolonged changes in behavioral and affective pain components.

Pain

Avec: Erika Ivanna Araya , Darciane Favero Baggio , Laura de Oliveira Koren , Roberto Andreatini , Rainer K W Schwarting , Juliana Geremias Chichorro

Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitis.

Molecular brain

Avec: Vinicius M Gadotti ,

T-type calcium channels: From molecule to therapeutic opportunities.

The international journal of biochemistry & cell biology

Avec: Norbert Weiss ,

Design, synthesis and pharmacological evaluation of some substituted dihydropyrimidines with L-/T-type calcium channel blocking activities.

Bioorganic chemistry

Avec: Mohamed Teleb , Ola H Rizk , Fang-Xiong Zhang , Frank R Fronczek , Hesham Fahmy

Peripheral nerve injury-induced alterations in VTA neuron firing properties.

Molecular brain

Avec: Shuo Huang , Stephanie L Borgland ,

The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels.

Molecular brain

Avec: Vinicius M Gadotti , Sun Huang ,

Analgesic effects of optogenetic inhibition of basolateral amygdala inputs into the prefrontal cortex in nerve injured female mice.

Molecular brain

Avec: Vinicius M Gadotti , Zizhen Zhang , Junting Huang ,

Interactions of Rabconnectin-3 with Cav2 calcium channels.

Molecular brain

Avec: Maria A Gandini , Ivana A Souza , Jing Fan , Katherine Li , Decheng Wang ,

Regulation of Ca

Pflugers Archiv : European journal of physiology

Avec: Maria A Gandini , Ivana A Souza , Abhishek Khullar , Eder Gambeta ,

The de novo CACNA1A pathogenic variant Y1384C associated with hemiplegic migraine, early onset cerebellar atrophy and developmental delay leads to a loss of Cav2.1 channel function.

Molecular brain

Avec: Maria A Gandini , Ivana A Souza , Laurent Ferron , A Micheil Innes ,

The IL33 receptor ST2 contributes to mechanical hypersensitivity in mice with neuropathic pain.

Molecular brain

Avec: Junting Huang , Vinicius M Gadotti , Zizhen Zhang ,

Rare functional missense variants in CACNA1H: What can we learn from Writer's cramp?

Molecular brain

Avec: Miaozhen Huang , Esther A R Nibbeling , Tjerk J Lagrand , Ivana A Souza , Justus L Groen , Maria A Gandini , Fang-Xiong Zhang , Johannes H T M Koelman , Noam Adir , Richard J Sinke , Marina A J Tijssen , Dineke S Verbeek

Central and peripheral contributions of T-type calcium channels in pain.

Molecular brain

Avec: Erika K Harding ,

SUMO wrestling in the cellular dohyō: crosstalk between phosphorylation and SUMOylation of PKCδ regulates oxidative cell damage.

The FEBS journal

Avec:

Subcellular localization of hippocampal ryanodine receptor 2 and its role in neuronal excitability and memory.

Communications biology

Avec: Florian Hiess , Jinjing Yao , Zhenpeng Song , Bo Sun , Zizhen Zhang , Junting Huang , Lina Chen , Adam Institoris , John Paul Estillore , Ruiwu Wang , Henk E D J Ter Keurs , Peter K Stys , Grant R Gordon , Anutosh Ganguly , S R Wayne Chen

Focusing on C-4 position of Hantzsch 1,4-dihydropyridines: Molecular modifications, enantioseparation, and binding mechanism to L- and T-type calcium channels.

European journal of medicinal chemistry

Avec: Dilara Akman , Katrin Denzinger , Sun Huang , J T Lee , Jordan W Nafie , Gerhard Wolber , Daniel W Armstrong , Miyase Gözde Gündüz

Voltage-gated calcium channels as potential therapeutic targets in migraine.

The journal of pain

Avec: Juliana G Chichorro , Eder Gambeta , Darciane F Baggio ,

Expression of GAD2 in excitatory neurons projecting from the ventrolateral periaqueductal gray to the locus coeruleus.

iScience

Avec: Erika K Harding , Zizhen Zhang , Julia Canet-Pons , Sierra Stokes-Heck , Tuan Trang ,

Functional identification of potential non-canonical N-glycosylation sites within Ca

Molecular brain

Avec: Vendula Ficelova , Ivana A Souza , Leos Cmarko , Maria A Gandini , Robin N Stringer , Norbert Weiss

A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav2.1 channels.

Molecular brain

Avec: Eder Gambeta , Maria A Gandini , Ivana A Souza , Laurent Ferron ,

Synthesis of some new C2 substituted dihydropyrimidines and their electrophysiological evaluation as L-/T-type calcium channel blockers.

Bioorganic chemistry

Avec: Mohamed Teleb , Ola H Rizk , Fang-Xiong Zhang , Frank R Fronczek , Hesham Fahmy

Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability.

Cell reports

Avec: Giriraj Sahu , Rima-Marie Wazen , Pina Colarusso , S R Wayne Chen , Ray W Turner

Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels.

Molecular brain

Avec: Catherine S W Choi , Ivana A Souza , Juan C Sanchez-Arias , Laura T Arbour , Leigh Anne Swayne

Opioid Receptor Regulation of Neuronal Voltage-Gated Calcium Channels.

Cellular and molecular neurobiology

Avec: Norbert Weiss ,

Mutation of copper binding sites on cellular prion protein abolishes its inhibitory action on NMDA receptors in mouse hippocampal neurons.

Molecular brain

Avec: Sun Huang , Stefanie A Black , Junting Huang , Peter K Stys ,

Modeling temperature- and Cav3 subtype-dependent alterations in T-type calcium channel mediated burst firing.

Molecular brain

Avec: Fernando R Fernandez , Mircea C Iftinca , Ray W Turner

Gut-innervating TRPV1+ Neurons Drive Chronic Visceral Pain via Microglial P2Y12 Receptor.

Cellular and molecular gastroenterology and hepatology

Avec: Manon Defaye , Nasser S Abdullah , Mircea Iftinca , Ahmed Hassan , Francina Agosti , Zizhen Zhang , Melissa Cumenal , Christophe Altier

Réseau de co-auteurs

Ivana A Souza 13 collaborations

Vinicius M Gadotti 9 collaborations

Zizhen Zhang 9 collaborations

Maria A Gandini 9 collaborations

Eder Gambeta 8 collaborations

Lina Chen 6 collaborations

Fang-Xiong Zhang 6 collaborations

Junting Huang 6 collaborations

Shuo Huang 5 collaborations

Norbert Weiss 5 collaborations

Sun Huang 4 collaborations

Agustin Garcia-Caballero 4 collaborations

Laurent Ferron 4 collaborations

Erika K Harding 4 collaborations

Stephanie L Borgland 3 collaborations

Robin N Stringer 3 collaborations

Ray W Turner 3 collaborations

Said M'Dahoma 2 collaborations

Gerhard Wolber 2 collaborations

Miyase Gözde Gündüz 2 collaborations

Decheng Wang 2 collaborations

Md Yousof Ali 2 collaborations

Sierra Stokes-Heck 2 collaborations

Julia Canet-Pons 2 collaborations

Darren J Derksen 2 collaborations

Tuan Trang 2 collaborations

Giriraj Sahu 2 collaborations

Mohamed Teleb 2 collaborations

Ola H Rizk 2 collaborations

Frank R Fronczek 2 collaborations

Hesham Fahmy 2 collaborations

Peter K Stys 2 collaborations

S R Wayne Chen 2 collaborations

Joanna M Kreitinger 1 collaboration

Nicholas B Wageling 1 collaboration

Dylan Budke 1 collaboration

Philippe Diaz 1 collaboration

Shi Chen Xu 1 collaboration

Catherine Thomas 1 collaboration

Nathan Godfrey 1 collaboration

Flávio Henrique Pequeno de Macedo 1 collaboration

Rosária Dias Aires 1 collaboration

Esdras Guedes Fonseca 1 collaboration

Renata Cristina Mendes Ferreira 1 collaboration

Daniel Portela Dias Machado 1 collaboration

Virgínia Soares Lemos 1 collaboration

Thiago Roberto Lima Romero 1 collaboration

Aubin Moutal 1 collaboration

Rajesh Khanna 1 collaboration

Jader S Cruz 1 collaboration

Bohumila Jurkovicova-Tarabova 1 collaboration

Omid Haji-Ghassemi 1 collaboration

Romane Idoux 1 collaboration

Anna Liashenko 1 collaboration

Yuriy Rzhepetskyy 1 collaboration

Lubica Lacinova 1 collaboration

Filip Van Petegem 1 collaboration

Roger Pamphlett 1 collaboration

Hande Aygün Cevher 1 collaboration

David Schaller 1 collaboration

Ozan Kaplan 1 collaboration

Fang Xiong Zhang 1 collaboration

Mustafa Çelebier 1 collaboration

Muhammad Nawaz Tahir 1 collaboration

Yan L Dang 1 collaboration

M Jackson Stutts 1 collaboration

Charu Ramakrishnan 1 collaboration

Karl Deisseroth 1 collaboration

Saloni Koshti 1 collaboration

Chris Bladen 1 collaboration

Jeffrey F Van Humbeck 1 collaboration

Justin L MacCallum 1 collaboration

Emilio R Mustafá 1 collaboration

Franz Kricek 1 collaboration

Christine Ruf 1 collaboration

Premji Meghani 1 collaboration

George Skouteris 1 collaboration

Charlie H T Kwok 1 collaboration

Nicole E Burma 1 collaboration

Tamara Markovic 1 collaboration

Nicolas Massaly 1 collaboration

Nynke J van den Hoogen 1 collaboration

Kristina Komarek 1 collaboration

Hye Jean Yoon 1 collaboration

Kathleen E Navis 1 collaboration

Brendan B McAllister 1 collaboration

Churmy Fan 1 collaboration

Rebecca Dalgarno 1 collaboration

Evgueni Gorobets 1 collaboration

James W Papatzimas 1 collaboration

Yuta Kohro 1 collaboration

Connor L Anderson 1 collaboration

Roger J Thompson 1 collaboration

Jose A Morón 1 collaboration

Ketul V Patel 1 collaboration

Flavia T T Antunes 1 collaboration

Xiaoqin Zhan 1 collaboration

Hadhimulya Asmara 1 collaboration

Ning Cheng 1 collaboration

Eduardo Sanchez 1 collaboration

Jong M Rho 1 collaboration

Erika Ivanna Araya 1 collaboration

Darciane Favero Baggio 1 collaboration

Laura de Oliveira Koren 1 collaboration

Roberto Andreatini 1 collaboration

Rainer K W Schwarting 1 collaboration

Juliana Geremias Chichorro 1 collaboration

Jing Fan 1 collaboration

Katherine Li 1 collaboration

Abhishek Khullar 1 collaboration

A Micheil Innes 1 collaboration

Miaozhen Huang 1 collaboration

Esther A R Nibbeling 1 collaboration

Tjerk J Lagrand 1 collaboration

Justus L Groen 1 collaboration

Johannes H T M Koelman 1 collaboration

Noam Adir 1 collaboration

Richard J Sinke 1 collaboration

Marina A J Tijssen 1 collaboration

Dineke S Verbeek 1 collaboration

Florian Hiess 1 collaboration

Jinjing Yao 1 collaboration

Zhenpeng Song 1 collaboration

Bo Sun 1 collaboration

Adam Institoris 1 collaboration

John Paul Estillore 1 collaboration

Ruiwu Wang 1 collaboration

Henk E D J Ter Keurs 1 collaboration

Grant R Gordon 1 collaboration

Anutosh Ganguly 1 collaboration

Dilara Akman 1 collaboration

Katrin Denzinger 1 collaboration

J T Lee 1 collaboration

Jordan W Nafie 1 collaboration

Daniel W Armstrong 1 collaboration

Juliana G Chichorro 1 collaboration

Darciane F Baggio 1 collaboration

Vendula Ficelova 1 collaboration

Leos Cmarko 1 collaboration

Rima-Marie Wazen 1 collaboration

Pina Colarusso 1 collaboration

Catherine S W Choi 1 collaboration

Juan C Sanchez-Arias 1 collaboration

Laura T Arbour 1 collaboration

Leigh Anne Swayne 1 collaboration

Stefanie A Black 1 collaboration

Fernando R Fernandez 1 collaboration

Mircea C Iftinca 1 collaboration

Manon Defaye 1 collaboration

Nasser S Abdullah 1 collaboration

Mircea Iftinca 1 collaboration

Ahmed Hassan 1 collaboration

Francina Agosti 1 collaboration

Melissa Cumenal 1 collaboration

Christophe Altier 1 collaboration