Geert Jan Groeneveld

Affiliations

Centre for Human Drug Research, Zernikedreef 8, 2333CL Leiden, the Netherlands.

Publications (22)

Pain-related changes in cutaneous innervation of patients suffering from bortezomib-induced, diabetic or chronic idiopathic axonal polyneuropathy.

Brain research

Avec: Malik Bechakra , Mariska D Nieuwenhoff , Joost van Rosmalen , Frank J P M Huygen , Chris I de Zeeuw , Pieter A van Doorn , Joost L M Jongen

Methylphenidate and galantamine in patients with vascular cognitive impairment-the proof-of-principle study STREAM-VCI.

Alzheimer's research & therapy

Avec: Jolien F Leijenaar , Erica S Klaassen , Anna E Leeuwis , Philip Scheltens , Henry C Weinstein , Joop M A van Gerven , Frederik Barkhof , Wiesje M van der Flier , Niels D Prins

DNL104, a Centrally Penetrant RIPK1 Inhibitor, Inhibits RIP1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers.

Clinical pharmacology and therapeutics

Avec: Hendrika W Grievink , Jules A A C Heuberger , Fen Huang , Rinkal Chaudhary , Willem A J Birkhoff , George R Tonn , Sofia Mosesova , Rebecca Erickson , Matthijs Moerland , Patrick C G Haddick , Kimberly Scearce-Levie , Carole Ho ,

Treatment of internuclear ophthalmoparesis in multiple sclerosis with fampridine: A randomized double-blind, placebo-controlled cross-over trial.

CNS neuroscience & therapeutics

Avec: Kawita M S Kanhai , Jenny A Nij Bijvank , Yorick L Wagenaar , Erica S Klaassen , KyoungSoo Lim , Sandrin C Bergheanu , Axel Petzold , Ajay Verma , Jacob Hesterman , Mike P Wattjes , Bernard M J Uitdehaag , Laurentius J van Rijn ,

Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop-seizure frequency.

British journal of clinical pharmacology

Avec: Kirsten Riber Bergmann , Karen Broekhuizen ,

The oral splicing modifier RG7800 increases full length survival of motor neuron 2 mRNA and survival of motor neuron protein: Results from trials in healthy adults and patients with spinal muscular atrophy.

Neuromuscular disorders : NMD

Avec: Heidemarie Kletzl , Anne Marquet , Andreas Günther , Wakana Tang , Jules Heuberger , Willem Birkhoff , Eugenio Mercuri , Hanns Lochmüller , Claire Wood , Dirk Fischer , Irene Gerlach , Katja Heinig , Teodorica Bugawan , Sebastian Dziadek , Russell Kinch , Christian Czech , Omar Khwaja

Kinetics of myelin breakdown products: A labeling study in patients with progressive multiple sclerosis.

Clinical and translational science

Avec: Kawita M S Kanhai , Sebastiaan C Goulooze , Jeroen van der Grond , Amy C Harms , Thomas Hankemeier , Ajay Verma , Gersham Dent , Juan Chavez , Henri Meijering ,

Acute response to cholinergic challenge predicts long-term response to galantamine treatment in patients with Alzheimer's disease.

British journal of clinical pharmacology

Avec: Anne Catrien Baakman , Carmen Gavan , Lotte van Doeselaar , Marieke de Kam , Karen Broekhuizen , Ovidiu Bajenaru , Laura Camps , Eleonora L Swart , Kees Kalisvaart , Niki Schoonenboom , Evelien Lemstra , Philip Scheltens , Adam Cohen , Joop van Gerven ,

A Randomized First-in-Human Study With UB-312, a UBITh® α-Synuclein Peptide Vaccine.

Movement disorders : official journal of the Movement Disorder Society

Avec: Hui Jing Yu , Eva Thijssen , Emilie van Brummelen , Johan L van der Plas , Igor Radanovic , Matthijs Moerland , Eric Hsieh , Jean-Cosme Dodart

Inflammatory plasma biomarkers in subjects with preclinical Alzheimer's disease.

Alzheimer's research & therapy

Avec: Samantha Prins , Marieke L de Kam , Charlotte E Teunissen ,

Neurocognitive Effect of Biased µ-Opioid Receptor Agonist Oliceridine, a Utility Function Analysis and Comparison with Morphine.

Anesthesiology

Avec: Laurence Moss , Hemme Hijma , Mark Demitrack , Jessica Kim , Monique van Velzen , Marieke Niesters , Erik Olofsen , Albert Dahan

Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery.

Journal of the neurological sciences

Avec: Samantha Prins , Laura Borghans , Marieke L de Kam , Joop van Gerven

The interactive walkway provides fit-for-purpose fall-risk biomarkers in the elderly: Comparison of zolpidem and suvorexant.

Clinical and translational science

Avec: Ingrid Koopmans , Daphne Geerse , Lara de Ridder , Melvyn Roerdink , Maria Joanna Juachon , Clemens Muehlan , Jasper Dingemanse , Joop van Gerven , Rob Zuiker

Safety, pharmacokinetics and pharmacodynamics of SBT-020 in patients with early stage Huntington's disease, a 2-part study.

British journal of clinical pharmacology

Avec: Marcus P J van Diemen , Ellen P Hart , Anthony Abbruscato , Liz Mead , Ilse van Beelen , Sandrin C Bergheanu , Pieter W Hameeteman , Emma Coppen , Jessica Y Winder , Matthijs Moerland , Hermien Kan , Jeroen van der Grond , Andrew Webb , Raymund A C Roos ,

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development.

Journal of visualized experiments : JoVE

Avec: Ellen P Hart , Ricardo Alvarez-Jimenez , Esther Davidse , Robert Jan Doll , Adam F Cohen , Joop M A Van Gerven ,

Lack of Detection of the Analgesic Properties of PF-05089771, a Selective Na

Clinical and translational science

Avec: Pieter Siebenga , Guido van Amerongen , Justin L Hay , Aoibhinn McDonnell , Donal Gorman , Richard Butt ,

Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABA

British journal of anaesthesia

Avec: Guido van Amerongen , Pieter S Siebenga , Rachel Gurrell , Pinky Dua , Mark Whitlock , Donal Gorman , Pieter Okkerse , Justin L Hay , Richard P Butt ,

Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals.

International journal of molecular sciences

Avec: Tian Qin , Samantha Prins , Gerard Van Westen , Helga E de Vries , Yin Cheong Wong , Luc J M Bischoff , Elizabeth C M de Lange

Safety and Pharmacokinetics of HTL0018318, a Novel M

Drugs in R&D

Avec: Charlotte Bakker , Jasper van der Aart , Geert Labots , Jan Liptrot , David M Cross , Erica S Klaassen , Steve Dickinson , Tim Tasker ,

First-in-human trial to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of STR-324, a dual enkephalinase inhibitor for pain management.

British journal of clinical pharmacology

Avec: Laurence M Moss , Cecile L Berends , Emilie M J van Brummelen , Ingrid M C Kamerling , Erica S Klaassen , Kirsten Bergmann , Vanessa Ville , Victor Juarez-Perez , Annie-Claude Benichou ,

Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double-blind, placebo-controlled, cross-over study.

British journal of clinical pharmacology

Avec: Titia Q Ruijs , Jules A A C Heuberger , Annika A de Goede , Dimitrios Ziagkos , Marije E Otto , Robert J Doll , Michel J A M van Putten ,

A phase I, randomized, double-blind, placebo-controlled, single- and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX-128, a highly selective Na

Clinical and translational science

Avec: Hemme J Hijma , Emilie M J van Brummelen , Pieter S Siebenga ,

Réseau de co-auteurs

Erica S Klaassen 4 collaborations

Matthijs Moerland 3 collaborations

Joop van Gerven 3 collaborations

Samantha Prins 3 collaborations

Philip Scheltens 2 collaborations

Jules A A C Heuberger 2 collaborations

Kawita M S Kanhai 2 collaborations

Sandrin C Bergheanu 2 collaborations

Ajay Verma 2 collaborations

Karen Broekhuizen 2 collaborations

Jeroen van der Grond 2 collaborations

Marieke L de Kam 2 collaborations

Ellen P Hart 2 collaborations

Guido van Amerongen 2 collaborations

Justin L Hay 2 collaborations

Donal Gorman 2 collaborations

Pieter S Siebenga 2 collaborations

Emilie M J van Brummelen 2 collaborations

Malik Bechakra 1 collaboration

Mariska D Nieuwenhoff 1 collaboration

Joost van Rosmalen 1 collaboration

Frank J P M Huygen 1 collaboration

Chris I de Zeeuw 1 collaboration

Pieter A van Doorn 1 collaboration

Joost L M Jongen 1 collaboration

Jolien F Leijenaar 1 collaboration

Anna E Leeuwis 1 collaboration

Henry C Weinstein 1 collaboration

Joop M A van Gerven 1 collaboration

Frederik Barkhof 1 collaboration

Wiesje M van der Flier 1 collaboration

Niels D Prins 1 collaboration

Hendrika W Grievink 1 collaboration

Fen Huang 1 collaboration

Rinkal Chaudhary 1 collaboration

Willem A J Birkhoff 1 collaboration

George R Tonn 1 collaboration

Sofia Mosesova 1 collaboration

Rebecca Erickson 1 collaboration

Patrick C G Haddick 1 collaboration

Kimberly Scearce-Levie 1 collaboration

Carole Ho 1 collaboration

Jenny A Nij Bijvank 1 collaboration

Yorick L Wagenaar 1 collaboration

KyoungSoo Lim 1 collaboration

Axel Petzold 1 collaboration

Jacob Hesterman 1 collaboration

Mike P Wattjes 1 collaboration

Bernard M J Uitdehaag 1 collaboration

Laurentius J van Rijn 1 collaboration

Kirsten Riber Bergmann 1 collaboration

Heidemarie Kletzl 1 collaboration

Anne Marquet 1 collaboration

Andreas Günther 1 collaboration

Wakana Tang 1 collaboration

Jules Heuberger 1 collaboration

Willem Birkhoff 1 collaboration

Eugenio Mercuri 1 collaboration

Hanns Lochmüller 1 collaboration

Claire Wood 1 collaboration

Dirk Fischer 1 collaboration

Irene Gerlach 1 collaboration

Katja Heinig 1 collaboration

Teodorica Bugawan 1 collaboration

Sebastian Dziadek 1 collaboration

Russell Kinch 1 collaboration

Christian Czech 1 collaboration

Omar Khwaja 1 collaboration

Sebastiaan C Goulooze 1 collaboration

Amy C Harms 1 collaboration

Thomas Hankemeier 1 collaboration

Gersham Dent 1 collaboration

Juan Chavez 1 collaboration

Henri Meijering 1 collaboration

Anne Catrien Baakman 1 collaboration

Carmen Gavan 1 collaboration

Lotte van Doeselaar 1 collaboration

Marieke de Kam 1 collaboration

Ovidiu Bajenaru 1 collaboration

Laura Camps 1 collaboration

Eleonora L Swart 1 collaboration

Kees Kalisvaart 1 collaboration

Niki Schoonenboom 1 collaboration

Evelien Lemstra 1 collaboration

Adam Cohen 1 collaboration

Hui Jing Yu 1 collaboration

Eva Thijssen 1 collaboration

Emilie van Brummelen 1 collaboration

Johan L van der Plas 1 collaboration

Igor Radanovic 1 collaboration

Eric Hsieh 1 collaboration

Jean-Cosme Dodart 1 collaboration

Charlotte E Teunissen 1 collaboration

Laurence Moss 1 collaboration

Hemme Hijma 1 collaboration

Mark Demitrack 1 collaboration

Jessica Kim 1 collaboration

Monique van Velzen 1 collaboration

Marieke Niesters 1 collaboration

Erik Olofsen 1 collaboration

Albert Dahan 1 collaboration

Laura Borghans 1 collaboration

Ingrid Koopmans 1 collaboration

Daphne Geerse 1 collaboration

Lara de Ridder 1 collaboration

Melvyn Roerdink 1 collaboration

Maria Joanna Juachon 1 collaboration

Clemens Muehlan 1 collaboration

Jasper Dingemanse 1 collaboration

Rob Zuiker 1 collaboration

Marcus P J van Diemen 1 collaboration

Anthony Abbruscato 1 collaboration

Liz Mead 1 collaboration

Ilse van Beelen 1 collaboration

Pieter W Hameeteman 1 collaboration

Emma Coppen 1 collaboration

Jessica Y Winder 1 collaboration

Hermien Kan 1 collaboration

Andrew Webb 1 collaboration

Raymund A C Roos 1 collaboration

Ricardo Alvarez-Jimenez 1 collaboration

Esther Davidse 1 collaboration

Robert Jan Doll 1 collaboration

Adam F Cohen 1 collaboration

Joop M A Van Gerven 1 collaboration

Pieter Siebenga 1 collaboration

Aoibhinn McDonnell 1 collaboration

Richard Butt 1 collaboration

Rachel Gurrell 1 collaboration

Pinky Dua 1 collaboration

Mark Whitlock 1 collaboration

Pieter Okkerse 1 collaboration

Richard P Butt 1 collaboration

Tian Qin 1 collaboration

Gerard Van Westen 1 collaboration

Helga E de Vries 1 collaboration

Yin Cheong Wong 1 collaboration

Luc J M Bischoff 1 collaboration

Elizabeth C M de Lange 1 collaboration

Charlotte Bakker 1 collaboration

Jasper van der Aart 1 collaboration

Geert Labots 1 collaboration

Jan Liptrot 1 collaboration

David M Cross 1 collaboration

Steve Dickinson 1 collaboration

Tim Tasker 1 collaboration

Laurence M Moss 1 collaboration

Cecile L Berends 1 collaboration

Ingrid M C Kamerling 1 collaboration

Kirsten Bergmann 1 collaboration

Vanessa Ville 1 collaboration

Victor Juarez-Perez 1 collaboration

Annie-Claude Benichou 1 collaboration

Titia Q Ruijs 1 collaboration

Annika A de Goede 1 collaboration

Dimitrios Ziagkos 1 collaboration

Marije E Otto 1 collaboration

Robert J Doll 1 collaboration

Michel J A M van Putten 1 collaboration

Hemme J Hijma 1 collaboration