Gary Gintant

Affiliations

Integrated Sciences and Technology, AbbVie Inc., North Chicago, Illinois, United States of America.

Publications (14)

T vector velocity: A new ECG biomarker for identifying drug effects on cardiac ventricular repolarization.

PloS one

Avec: Werner Bystricky , Christoph Maier , Dennis Bergau , Kent Kamradt , Patrick Welsh , David Carter

Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.

Regulatory toxicology and pharmacology : RTP

Avec: Emily Pfeiffer Kaushik , Tromondae Feaster , Sonja Stoelzle-Feix , Yasunari Kanda , Tomoharu Osada , Godfrey Smith , Katherine Czysz , Ralf Kettenhofen , Hua Rong Lu , Beibei Cai , Hong Shi , Todd Joseph Herron , Qianyu Dang , Francis Burton , Li Pang , Martin Traebert , Yama Abassi , Jennifer Beck Pierson , Ksenia Blinova

Considerations for an

Frontiers in pharmacology

Avec: Alexandre J S Ribeiro , Brian D Guth , Michael Engwall , Sandy Eldridge , C Michael Foley , Liang Guo , John Koerner , Stanley T Parish , Jennifer B Pierson , Mathew Brock , Khuram W Chaudhary , Yasunari Kanda , Brian Berridge

Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting.

Therapeutic innovation & regulatory science

Avec: David G Strauss , Zhihua Li , Wendy Wu , Ksenia Blinova , Jose Vicente , J Rick Turner , Philip T Sager

Assessing the fidelity of translation of non-clinical assays: a Pharma perspective.

British journal of pharmacology

Avec:

The Challenges of Predicting Drug-Induced QTc Prolongation in Humans.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Jean-Pierre Valentin , Peter Hoffmann , Catherine Ortemann-Renon , John Koerner , Jennifer Pierson , James Willard , Christine Garnett , Matthew Skinner , Hugo M Vargas , Todd Wisialowski , Michael K Pugsley

The roles of human induced pluripotent stem cell-derived cardiomyocytes in drug discovery: managing in vitro safety study expectations.

Expert opinion on drug discovery

Avec: Martin Traebert

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association.

Circulation research

Avec: Paul Burridge , Lior Gepstein , Sian Harding , Todd Herron , Charles Hong , José Jalife , Joseph C Wu

Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na

Bioorganic & medicinal chemistry

Avec: Meena V Patel , Hillary M Peltier , Mark A Matulenko , John R Koenig , Marc J C Scanio , Rebecca J Gum , Odile F El-Kouhen , Meagan M Fricano , Greta L Lundgaard , Torben Neelands , Xu-Feng Zhang , Cenchen Zhan , Madhavi Pai , Nayereh Ghoreishi-Haack , Thomas Hudzik , Ruth Martin , Steve McGaraughty , Jun Xu , Daniel Bow , John C Kalvass , Philip R Kym , David A DeGoey , Michael E Kort

Considerations for an

Frontiers in pharmacology

Avec: Brian D Guth , Michael Engwall , Sandy Eldridge , C Michael Foley , Liang Guo , John Koerner , Stanley T Parish , Jennifer B Pierson , Alexandre J S Ribeiro , Tanja Zabka , Khuram W Chaudhary , Yasunari Kanda , Brian Berridge

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Scientific reports

Avec: James Kramer , Herbert M Himmel , Anders Lindqvist , Sonja Stoelzle-Feix , Khuram W Chaudhary , Dingzhou Li , Georg Andrees Bohme , Matthew Bridgland-Taylor , Simon Hebeisen , Jingsong Fan , Muthukrishnan Renganathan , John Imredy , Edward S A Humphries , Nina Brinkwirth , Tim Strassmaier , Atsushi Ohtsuki , Timm Danker , Carlos Vanoye , Liudmila Polonchuk , Bernard Fermini , Jennifer Beck Pierson ,

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Scientific reports

Identification of Drug-Induced Multichannel Block and Proarrhythmic Risk in Humans Using Continuous T Vector Velocity Effect Profiles Derived From Surface Electrocardiograms.

Frontiers in physiology

Avec: Werner Bystricky , Christoph Maier , Dennis Bergau , David Carter

Cardiovascular microphysiological systems (CVMPS) for safety studies - a pharma perspective.

Lab on a chip

Avec: Amy Pointon , Jonathan Maher , Myrtle Davis , Thomas Baker , Joseph Cichocki , Diane Ramsden , Christopher Hale , Kyle L Kolaja , Paul Levesque , Radhakrishna Sura , David M Stresser ,

Réseau de co-auteurs

Khuram W Chaudhary 4 collaborations

Sonja Stoelzle-Feix 3 collaborations

Yasunari Kanda 3 collaborations

Jennifer Beck Pierson 3 collaborations

John Koerner 3 collaborations

Werner Bystricky 2 collaborations

Christoph Maier 2 collaborations

Dennis Bergau 2 collaborations

David Carter 2 collaborations

Martin Traebert 2 collaborations

Ksenia Blinova 2 collaborations

Alexandre J S Ribeiro 2 collaborations

Brian D Guth 2 collaborations

Michael Engwall 2 collaborations

Sandy Eldridge 2 collaborations

C Michael Foley 2 collaborations

Liang Guo 2 collaborations

Stanley T Parish 2 collaborations

Jennifer B Pierson 2 collaborations

Brian Berridge 2 collaborations

James Kramer 2 collaborations

Herbert M Himmel 2 collaborations

Anders Lindqvist 2 collaborations

Dingzhou Li 2 collaborations

Georg Andrees Bohme 2 collaborations

Matthew Bridgland-Taylor 2 collaborations

Simon Hebeisen 2 collaborations

Jingsong Fan 2 collaborations

Muthukrishnan Renganathan 2 collaborations

John Imredy 2 collaborations

Edward S A Humphries 2 collaborations

Nina Brinkwirth 2 collaborations

Tim Strassmaier 2 collaborations

Atsushi Ohtsuki 2 collaborations

Timm Danker 2 collaborations

Carlos Vanoye 2 collaborations

Liudmila Polonchuk 2 collaborations

Bernard Fermini 2 collaborations

Kent Kamradt 1 collaboration

Patrick Welsh 1 collaboration

Emily Pfeiffer Kaushik 1 collaboration

Tromondae Feaster 1 collaboration

Tomoharu Osada 1 collaboration

Godfrey Smith 1 collaboration

Katherine Czysz 1 collaboration

Ralf Kettenhofen 1 collaboration

Hua Rong Lu 1 collaboration

Beibei Cai 1 collaboration

Hong Shi 1 collaboration

Todd Joseph Herron 1 collaboration

Qianyu Dang 1 collaboration

Francis Burton 1 collaboration

Li Pang 1 collaboration

Yama Abassi 1 collaboration

Mathew Brock 1 collaboration

David G Strauss 1 collaboration

Zhihua Li 1 collaboration

Wendy Wu 1 collaboration

Jose Vicente 1 collaboration

J Rick Turner 1 collaboration

Philip T Sager 1 collaboration

Jean-Pierre Valentin 1 collaboration

Peter Hoffmann 1 collaboration

Catherine Ortemann-Renon 1 collaboration

Jennifer Pierson 1 collaboration

James Willard 1 collaboration

Christine Garnett 1 collaboration

Matthew Skinner 1 collaboration

Hugo M Vargas 1 collaboration

Todd Wisialowski 1 collaboration

Michael K Pugsley 1 collaboration

Paul Burridge 1 collaboration

Lior Gepstein 1 collaboration

Sian Harding 1 collaboration

Todd Herron 1 collaboration

Charles Hong 1 collaboration

José Jalife 1 collaboration

Joseph C Wu 1 collaboration

Meena V Patel 1 collaboration

Hillary M Peltier 1 collaboration

Mark A Matulenko 1 collaboration

John R Koenig 1 collaboration

Marc J C Scanio 1 collaboration

Rebecca J Gum 1 collaboration

Odile F El-Kouhen 1 collaboration

Meagan M Fricano 1 collaboration

Greta L Lundgaard 1 collaboration

Torben Neelands 1 collaboration

Xu-Feng Zhang 1 collaboration

Cenchen Zhan 1 collaboration

Madhavi Pai 1 collaboration

Nayereh Ghoreishi-Haack 1 collaboration

Thomas Hudzik 1 collaboration

Ruth Martin 1 collaboration

Steve McGaraughty 1 collaboration

Jun Xu 1 collaboration

Daniel Bow 1 collaboration

John C Kalvass 1 collaboration

Philip R Kym 1 collaboration

David A DeGoey 1 collaboration

Michael E Kort 1 collaboration

Tanja Zabka 1 collaboration

Amy Pointon 1 collaboration

Jonathan Maher 1 collaboration

Myrtle Davis 1 collaboration

Thomas Baker 1 collaboration

Joseph Cichocki 1 collaboration

Diane Ramsden 1 collaboration

Christopher Hale 1 collaboration

Kyle L Kolaja 1 collaboration

Paul Levesque 1 collaboration

Radhakrishna Sura 1 collaboration

David M Stresser 1 collaboration