Floris C Loeff

Affiliations

Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: F.C.Loeff@lumc.nl.

Publications (21)

Impact of alemtuzumab pharmacokinetics on T-cell dynamics, graft-versus-host disease and viral reactivation in patients receiving allogeneic stem cell transplantation with an alemtuzumab-based T-cell-depleted graft.

Transplant immunology

Avec: Esther H M van Egmond , Dirk J A R Moes , Charissa Wijnands , Peter A Von Dem Borne , Hendrik Veelken , J H Frederik Falkenburg , Inge Jedema , Constantijn J M Halkes

Development of a SARS-CoV-2 Total Antibody Assay and the Dynamics of Antibody Response over Time in Hospitalized and Nonhospitalized Patients with COVID-19.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Erik H Vogelzang , Ninotska I L Derksen , Simone Kruithof , Pleuni Ooijevaar-de Heer , Gerard van Mierlo , Federica Linty , Juk Yee Mok , Wim van Esch , Sanne de Bruin , Alexander P J Vlaar , Auteur inconnu , Bart Seppen , Maureen Leeuw , Anne J G van Oudheusden , Anton G M Buiting , Kin Ki Jim , Hans Vrielink , Francis Swaneveld , Gestur Vidarsson , C Ellen van der Schoot , Peter C Wever , Wentao Li , Frank van Kuppeveld , Jean-Luc Murk , Berend Jan Bosch , Gerrit-Jan Wolbink , Theo Rispens

Therapeutic Drug Monitoring of Vedolizumab in Inflammatory Bowel Disease Patients during Maintenance Treatment-TUMMY Study.

Pharmaceutics

Avec: Merve Sivridaş , Rob H Creemers , Dennis R Wong , Paul J Boekema , Tessa E H Römkens , Lennard P L Gilissen , Adriaan A van Bodegraven , Theo Rispens , Luc J J Derijks

The effect of certolizumab drug concentration and anti-drug antibodies on TNF neutralisation.

Clinical and experimental rheumatology

Avec: Lea C Berkhout , Erik H Vogelzang , Margreet M Hart , Lisanne Dijk , Ninotska I L Derksen , Roeland Wieringa , W Astrid van Leeuwen , Charlotte L M Krieckaert , Annick de Vries , Michael T Nurmohamed , Gerrit J Wolbink , Theo Rispens

Patient-perspective and feasibility of home finger-prick testing to complement and facilitate large-scale research in rheumatology.

RMD open

Avec: Yaëlle R Besten , Laura Boekel , Maurice Steenhuis , Femke Hooijberg , Sadaf Atiqi , Maureen Leeuw , Erik H Vogelzang , Jim Keijser , Sofie Keijzer , Martijn Gerritsen , Sander W Tas , Michael T Nurmohamed , Theo Rispens , Gertjan Wolbink

Ocrelizumab Concentration Is a Good Predictor of SARS-CoV-2 Vaccination Response in Patients with Multiple Sclerosis.

Annals of neurology

Avec: Zoé L E van Kempen , Laura Hogenboom , Alyssa A Toorop , Maurice Steenhuis , Eileen W Stalman , Laura Y L Kummer , Koos P J van Dam , Karien Bloem , Anja Ten Brinke , S Marieke van Ham , Taco W Kuijpers , Gerrit J Wolbink , Luuk Wieske , Filip Eftimov , Theo Rispens , Eva M M Strijbis , Joep Killestein , Auteur inconnu

Clinical Validation of a Capillary Blood Home-Based Self-Sampling Technique for Monitoring of Infliximab, Vedolizumab, and C-Reactive Protein Concentrations in Patients With Inflammatory Bowel Disease.

Inflammatory bowel diseases

Avec: Antonius T Otten , Hedwig H van der Meulen , Maurice Steenhuis , Daan J Touw , Jos G W Kosterink , Henderik W Frijlink , Theo Rispens , Gerard Dijkstra , Marijn C Visschedijk , Arno R Bourgonje

Association of Serum Ustekinumab Levels With Clinical Response in Psoriasis.

JAMA dermatology

Avec: Teresa Tsakok , Nina Wilson , Nick Dand , Karien Bloem , David Baudry , Michael Duckworth , Shan Pan , Angela Pushpa-Rajah , Joseph F Standing , Annick de Vries , Ali Alsharqi , Gabrielle Becher , Ruth Murphy , Shyamal Wahie , Andrew Wright , Christopher E M Griffiths , Nick J Reynolds , Jonathan Barker , Richard B Warren , A David Burden , Theo Rispens , Deborah Stocken , Catherine Smith , Auteur inconnu

Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study.

Clinical and translational science

Avec: Shan Pan , Teresa Tsakok , Nick Dand , Dagan O Lonsdale , Karien Bloem , Annick de Vries , David Baudry , Michael Duckworth , Satveer Mahil , Angela Pushpa-Rajah , Alice Russell , Ali Alsharqi , Gabrielle Becher , Ruth Murphy , Shyamal Wahie , Andrew Wright , Christopher E M Griffiths , Nick J Reynolds , Jonathan Barker , Richard B Warren , A David Burden , Theo Rispens , Joseph F Standing , Catherine H Smith , Auteur inconnu

Case report: Pharmacokinetics of pembrolizumab in a patient with stage IV non-small cell lung cancer after a single 200 mg administration.

Frontiers in oncology

Avec: Fenna de Vries , Adrianus A J Smit , Gertjan Wolbink , Annick de Vries , Eric J F Franssen

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.

Pharmaceutics

Avec: Erin H Smeijsters , Kim C M van der Elst , Amy Visch , Camiel Göbel , Theo Rispens , Alwin D R Huitema , Matthijs van Luin , Mohsin El Amrani

Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove.

JCI insight

Avec: Teresa Tsakok , Jake Saklatvala , Theo Rispens , Annick de Vries , Michael H Allen , Ines A Barbosa , David Baudry , Tejus Dasandi , Michael Duckworth , Freya Meynell , Alice Russell , Anna Chapman , Sandy McBride , Kevin McKenna , Gayathri Perera , Helen Ramsay , Raakhee Ramesh , Kathleen Sands , Alexa Shipman , Auteur inconnu , A David Burden , Christopher Em Griffiths , Nick J Reynolds , Richard B Warren , Satveer Mahil , Jonathan Barker , Nick Dand , Catherine Smith , Michael A Simpson

Belimumab concentration measurements using a homologous anti-idiotype immunoassay.

Journal of immunological methods

Avec: Ioannis Parodis , Tomas Walhelm , Andreas Jönsen , Dionysis Nikolopoulos , Christopher Sjöwall , Anders A Bengtsson , Dorien Kos , Astrid van Leeuwen , Bryan van den Broek , Lisanne Dijk , Jorn Jeremiasse , Birgit S Blomjous , Alexandre E Voskuyl , Gerrit Jan Wolbink , Irene E M Bultink , Theo Rispens

Clinical Impact of Antibodies against Ustekinumab in Psoriasis: An Observational, Cross-Sectional, Multicenter Study.

The Journal of investigative dermatology

Avec: Teresa Tsakok , Lisanne Dijk , Margreet H Hart , Michael Duckworth , David Baudry , Alice Russell , Nick Dand , Astrid van Leeuwen , Christopher E M Griffiths , Nick J Reynolds , Jonathan Barker , A David Burden , Richard B Warren , Annick de Vries , Karien Bloem , Gerrit Jan Wolbink , Catherine H Smith , Theo Rispens , Auteur inconnu , Auteur inconnu , Auteur inconnu

Biased anti-idiotype response in rabbits leads to high-affinity monoclonal antibodies to biologics.

mAbs

Avec: Christina Großerichter-Wagener , Dorien Kos , Astrid van Leeuwen , Lisanne Dijk , Jorn Jeremiasse , Theo Rispens

Immunogenicity of TNF-Inhibitors.

Frontiers in immunology

Avec: Sadaf Atiqi , Femke Hooijberg , Theo Rispens , Gerrit J Wolbink

Loss of the GPI-anchor in B-lymphoblastic leukemia by epigenetic downregulation of PIGH expression.

American journal of hematology

Avec: Kevin Rijs , Esther H M van Egmond , Willem H Zoutman , Xiaohang Qiao , Wilhelmina G M Kroes , Sabrina A J Veld , Marieke Griffioen , Maarten H Vermeer , Jacques Neefjes , J H Frederik Falkenburg , Constantijn J M Halkes , Inge Jedema

Antibody development and disease severity of COVID-19 in non-immunised patients with rheumatic immune-mediated inflammatory diseases: data from a prospective cohort study.

RMD open

Avec: Laura Boekel , Femke Hooijberg , Erik H Vogelzang , Yaëlle R Besten , Maureen Leeuw , Sadaf Atiqi , Ronald F van Vollenhoven , Carla A Wijbrandts , Martijn Gerritsen , C Krieckaert , Bas Dijkshoorn , Siham Bakhlakh , Juliette J Crooijmans , Alexandre Voskuyl , Irene E van der Horst-Bruinsma , Willem Lems , Taco W Kuijpers , S Marieke van Ham , Luuk Wieske , Filip Eftimov , Laura Y Kummer , Pj Koos van Dam , Eileen W Stalman , Maurice Steenhuis , Sofie Keijzer , Olvi Cristianawati , Jim Keijser , Sander W Tas , Michael T Nurmohamed , Maarten Boers , Theo Rispens , Gertjan Wolbink

The clinical relevance of dupilumab serum concentration in patients with atopic dermatitis: a two-center prospective cohort study.

The Journal of dermatological treatment

Avec: Angela L Bosma , Louise A A Gerbens , Hajar El Khattabi , Michael Duckworth , Richard T Woolf , Theo Rispens , Catherine H Smith , Phyllis I Spuls

Fingerprick blood samples to measure serum natalizumab concentrations.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Alyssa A Toorop , Maurice Steenhuis , Suzanne S Weijers , Joep Killestein , Theo Rispens , Zoé LE van Kempen

Subcutaneous administration of natalizumab can lead to lower drug concentrations compared to intravenous administration.

Multiple sclerosis and related disorders

Avec: Liza M Y Gelissen , Sam Loveless , Alyssa A Toorop , Jayne Howlett , Theo Rispens , Joep Killestein , Emma C Tallantyre , Zoé L E van Kempen

Réseau de co-auteurs

Theo Rispens 18 collaborations

None None 8 collaborations

Annick de Vries 6 collaborations

Maurice Steenhuis 5 collaborations

Michael Duckworth 5 collaborations

Erik H Vogelzang 4 collaborations

Lisanne Dijk 4 collaborations

Karien Bloem 4 collaborations

Teresa Tsakok 4 collaborations

Nick Dand 4 collaborations

David Baudry 4 collaborations

Nick J Reynolds 4 collaborations

Jonathan Barker 4 collaborations

Richard B Warren 4 collaborations

A David Burden 4 collaborations

Maureen Leeuw 3 collaborations

Michael T Nurmohamed 3 collaborations

Gerrit J Wolbink 3 collaborations

Femke Hooijberg 3 collaborations

Sadaf Atiqi 3 collaborations

Gertjan Wolbink 3 collaborations

Alyssa A Toorop 3 collaborations

Joep Killestein 3 collaborations

Christopher E M Griffiths 3 collaborations

Alice Russell 3 collaborations

Catherine H Smith 3 collaborations

Astrid van Leeuwen 3 collaborations

Esther H M van Egmond 2 collaborations

J H Frederik Falkenburg 2 collaborations

Inge Jedema 2 collaborations

Constantijn J M Halkes 2 collaborations

Ninotska I L Derksen 2 collaborations

Yaëlle R Besten 2 collaborations

Laura Boekel 2 collaborations

Jim Keijser 2 collaborations

Sofie Keijzer 2 collaborations

Martijn Gerritsen 2 collaborations

Sander W Tas 2 collaborations

Zoé L E van Kempen 2 collaborations

Eileen W Stalman 2 collaborations

S Marieke van Ham 2 collaborations

Taco W Kuijpers 2 collaborations

Luuk Wieske 2 collaborations

Filip Eftimov 2 collaborations

Shan Pan 2 collaborations

Angela Pushpa-Rajah 2 collaborations

Joseph F Standing 2 collaborations

Ali Alsharqi 2 collaborations

Gabrielle Becher 2 collaborations

Ruth Murphy 2 collaborations

Shyamal Wahie 2 collaborations

Andrew Wright 2 collaborations

Catherine Smith 2 collaborations

Satveer Mahil 2 collaborations

Dorien Kos 2 collaborations

Jorn Jeremiasse 2 collaborations

Gerrit Jan Wolbink 2 collaborations

Dirk J A R Moes 1 collaboration

Charissa Wijnands 1 collaboration

Peter A Von Dem Borne 1 collaboration

Hendrik Veelken 1 collaboration

Simone Kruithof 1 collaboration

Pleuni Ooijevaar-de Heer 1 collaboration

Gerard van Mierlo 1 collaboration

Federica Linty 1 collaboration

Juk Yee Mok 1 collaboration

Wim van Esch 1 collaboration

Sanne de Bruin 1 collaboration

Alexander P J Vlaar 1 collaboration

Bart Seppen 1 collaboration

Anne J G van Oudheusden 1 collaboration

Anton G M Buiting 1 collaboration

Kin Ki Jim 1 collaboration

Hans Vrielink 1 collaboration

Francis Swaneveld 1 collaboration

Gestur Vidarsson 1 collaboration

C Ellen van der Schoot 1 collaboration

Peter C Wever 1 collaboration

Wentao Li 1 collaboration

Frank van Kuppeveld 1 collaboration

Jean-Luc Murk 1 collaboration

Berend Jan Bosch 1 collaboration

Gerrit-Jan Wolbink 1 collaboration

Merve Sivridaş 1 collaboration

Rob H Creemers 1 collaboration

Dennis R Wong 1 collaboration

Paul J Boekema 1 collaboration

Tessa E H Römkens 1 collaboration

Lennard P L Gilissen 1 collaboration

Adriaan A van Bodegraven 1 collaboration

Luc J J Derijks 1 collaboration

Lea C Berkhout 1 collaboration

Margreet M Hart 1 collaboration

Roeland Wieringa 1 collaboration

W Astrid van Leeuwen 1 collaboration

Charlotte L M Krieckaert 1 collaboration

Laura Hogenboom 1 collaboration

Laura Y L Kummer 1 collaboration

Koos P J van Dam 1 collaboration

Anja Ten Brinke 1 collaboration

Eva M M Strijbis 1 collaboration

Antonius T Otten 1 collaboration

Hedwig H van der Meulen 1 collaboration

Daan J Touw 1 collaboration

Jos G W Kosterink 1 collaboration

Henderik W Frijlink 1 collaboration

Gerard Dijkstra 1 collaboration

Marijn C Visschedijk 1 collaboration

Arno R Bourgonje 1 collaboration

Nina Wilson 1 collaboration

Deborah Stocken 1 collaboration

Dagan O Lonsdale 1 collaboration

Fenna de Vries 1 collaboration

Adrianus A J Smit 1 collaboration

Eric J F Franssen 1 collaboration

Erin H Smeijsters 1 collaboration

Kim C M van der Elst 1 collaboration

Amy Visch 1 collaboration

Camiel Göbel 1 collaboration

Alwin D R Huitema 1 collaboration

Matthijs van Luin 1 collaboration

Mohsin El Amrani 1 collaboration

Jake Saklatvala 1 collaboration

Michael H Allen 1 collaboration

Ines A Barbosa 1 collaboration

Tejus Dasandi 1 collaboration

Freya Meynell 1 collaboration

Anna Chapman 1 collaboration

Sandy McBride 1 collaboration

Kevin McKenna 1 collaboration

Gayathri Perera 1 collaboration

Helen Ramsay 1 collaboration

Raakhee Ramesh 1 collaboration

Kathleen Sands 1 collaboration

Alexa Shipman 1 collaboration

Christopher Em Griffiths 1 collaboration

Michael A Simpson 1 collaboration

Ioannis Parodis 1 collaboration

Tomas Walhelm 1 collaboration

Andreas Jönsen 1 collaboration

Dionysis Nikolopoulos 1 collaboration

Christopher Sjöwall 1 collaboration

Anders A Bengtsson 1 collaboration

Bryan van den Broek 1 collaboration

Birgit S Blomjous 1 collaboration

Alexandre E Voskuyl 1 collaboration

Irene E M Bultink 1 collaboration

Margreet H Hart 1 collaboration

Christina Großerichter-Wagener 1 collaboration

Kevin Rijs 1 collaboration

Willem H Zoutman 1 collaboration

Xiaohang Qiao 1 collaboration

Wilhelmina G M Kroes 1 collaboration

Sabrina A J Veld 1 collaboration

Marieke Griffioen 1 collaboration

Maarten H Vermeer 1 collaboration

Jacques Neefjes 1 collaboration

Ronald F van Vollenhoven 1 collaboration

Carla A Wijbrandts 1 collaboration

C Krieckaert 1 collaboration

Bas Dijkshoorn 1 collaboration

Siham Bakhlakh 1 collaboration

Juliette J Crooijmans 1 collaboration

Alexandre Voskuyl 1 collaboration

Irene E van der Horst-Bruinsma 1 collaboration

Willem Lems 1 collaboration

Laura Y Kummer 1 collaboration

Pj Koos van Dam 1 collaboration

Olvi Cristianawati 1 collaboration

Maarten Boers 1 collaboration

Angela L Bosma 1 collaboration

Louise A A Gerbens 1 collaboration

Hajar El Khattabi 1 collaboration

Richard T Woolf 1 collaboration

Phyllis I Spuls 1 collaboration

Suzanne S Weijers 1 collaboration

Zoé LE van Kempen 1 collaboration

Liza M Y Gelissen 1 collaboration

Sam Loveless 1 collaboration

Jayne Howlett 1 collaboration

Emma C Tallantyre 1 collaboration