Emma Scaletti

Affiliations

Department of Biochemistry and Biophysics, Stockholm University, Sweden.
Department of Experimental Medical Science, Lund University, Sweden.

Publications (7)

Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs.

FEBS letters

Avec: Ann-Sofie Jemth , Thomas Helleday , Pål Stenmark

Discovery of AB680: A Potent and Selective Inhibitor of CD73.

Journal of medicinal chemistry

Avec: Kenneth V Lawson , Jaroslaw Kalisiak , Erick A Lindsey , Eric T Newcomb , Manmohan Reddy Leleti , Laurent Debien , Brandon R Rosen , Dillon H Miles , Ehesan U Sharif , Jenna L Jeffrey , Joanne B L Tan , Ada Chen , Sharon Zhao , Guifen Xu , Lijuan Fu , Lixia Jin , Tim W Park , Wade Berry , Susanne Moschütz , Norbert Sträter , Nigel P Walker , Stephen W Young , Matthew J Walters , Uli Schindler , Jay P Powers

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

Journal of medicinal chemistry

Avec: Sanjay Bhattarai , Jan Pippel , Riham Idris , Marianne Freundlieb , Georg Rolshoven , Christian Renn , Sang-Yong Lee , Aliaa Abdelrahman , Herbert Zimmermann , Ali El-Tayeb , Christa E Müller , Norbert Sträter

Crystal Structure and Substrate Specificity of the 8-oxo-dGTP Hydrolase NUDT1 from Arabidopsis thaliana.

Biochemistry

Avec: Ann-Sofie Jemth , Megan Carter , Thomas Helleday , Pål Stenmark

Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives.

Purinergic signalling

Avec: Franziska U Huschmann , Uwe Mueller , Manfred S Weiss , Norbert Sträter

The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.

Journal of molecular biology

Avec: Magnus Claesson , Thomas Helleday , Ann-Sofie Jemth , Pål Stenmark

Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.

The Journal of biological chemistry

Avec: Daniel Rehling , Si Min Zhang , Ann-Sofie Jemth , Tobias Koolmeister , Adam Throup , Olov Wallner , Takaya Moriyama , Rina Nishii , Jonathan Davies , Matthieu Desroses , Sean G Rudd , Martin Scobie , Evert Homan , Ulrika Warpman Berglund , Jun J Yang , Thomas Helleday , Pål Stenmark

Réseau de co-auteurs

Ann-Sofie Jemth 4 collaborations

Thomas Helleday 4 collaborations

Pål Stenmark 4 collaborations

Norbert Sträter 3 collaborations

Kenneth V Lawson 1 collaboration

Jaroslaw Kalisiak 1 collaboration

Erick A Lindsey 1 collaboration

Eric T Newcomb 1 collaboration

Manmohan Reddy Leleti 1 collaboration

Laurent Debien 1 collaboration

Brandon R Rosen 1 collaboration

Dillon H Miles 1 collaboration

Ehesan U Sharif 1 collaboration

Jenna L Jeffrey 1 collaboration

Joanne B L Tan 1 collaboration

Ada Chen 1 collaboration

Sharon Zhao 1 collaboration

Guifen Xu 1 collaboration

Lijuan Fu 1 collaboration

Lixia Jin 1 collaboration

Tim W Park 1 collaboration

Wade Berry 1 collaboration

Susanne Moschütz 1 collaboration

Nigel P Walker 1 collaboration

Stephen W Young 1 collaboration

Matthew J Walters 1 collaboration

Uli Schindler 1 collaboration

Jay P Powers 1 collaboration

Sanjay Bhattarai 1 collaboration

Jan Pippel 1 collaboration

Riham Idris 1 collaboration

Marianne Freundlieb 1 collaboration

Georg Rolshoven 1 collaboration

Christian Renn 1 collaboration

Sang-Yong Lee 1 collaboration

Aliaa Abdelrahman 1 collaboration

Herbert Zimmermann 1 collaboration

Ali El-Tayeb 1 collaboration

Christa E Müller 1 collaboration

Megan Carter 1 collaboration

Franziska U Huschmann 1 collaboration

Uwe Mueller 1 collaboration

Manfred S Weiss 1 collaboration

Magnus Claesson 1 collaboration

Daniel Rehling 1 collaboration

Si Min Zhang 1 collaboration

Tobias Koolmeister 1 collaboration

Adam Throup 1 collaboration

Olov Wallner 1 collaboration

Takaya Moriyama 1 collaboration

Rina Nishii 1 collaboration

Jonathan Davies 1 collaboration

Matthieu Desroses 1 collaboration

Sean G Rudd 1 collaboration

Martin Scobie 1 collaboration

Evert Homan 1 collaboration

Ulrika Warpman Berglund 1 collaboration

Jun J Yang 1 collaboration