Diana L Blithe

Affiliations

Contraceptive Development Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6710B Rockledge Dr, Bethesda, MD 20817.

Publications (35)

Comparison of self-reported female condom failure and biomarker-confirmed semen exposure.

Contraception

Avec: Terri L Walsh , Margaret C Snead , Breione J St Claire , Jill L Schwartz , Christine K Mauck , Ron G Frezieres , David F Archer , Kurt T Barnhart , Jeffrey T Jensen , Anita L Nelson , Michael A Thomas , Livia S Wan , Mark A Weaver

Comparison of metabolic effects of the progestational androgens dimethandrolone undecanoate and 11β-MNTDC in healthy men.

Andrology

Avec: Fiona Yuen , Arthi Thirumalai , Frances A Fernando , Ronald S Swerdloff , Peter Y Liu , Youngju Pak , Laura Hull , Rachelle Bross , Jill E Long , Stephanie T Page , Christina Wang

Menstrual Cup Use and Intrauterine Device Expulsion in a Copper Intrauterine Device Randomized Trial.

Contraception

Avec: Jill Brown , Mitchell D Creinin , Hongsheng Wu , David Hubacher , Courtney A Schreiber , Bliss Kaneshiro , Kavita Nanda ,

Acceptability of oral dimethandrolone undecanoate in a 28-day placebo-controlled trial of a hormonal male contraceptive prototype.

Contraception

Avec: Brian T Nguyen , Maritza T Farrant , Bradley D Anawalt , Fiona Yuen , Arthi Thirumalai , John K Amory , Ronald S Swerdloff , William J Bremner , Peter Y Liu , Stephanie T Page , Christina Wang

Bone turnover markers in women participating in a dose-finding trial of a contraceptive vaginal ring releasing Nestorone and estradiol.

Contraception

Avec: Molly Tiedeken , Carolyn L Westhoff , Adi Cohen , Serge Cremers , Regine Sitruk-Ware , Auteur inconnu

Male Contraceptive Development: Update on Novel Hormonal and Nonhormonal Methods.

Clinical chemistry

Avec: Jill E Long , Min S Lee ,

Pharmacodynamics and pharmacokinetics of a copper intrauterine contraceptive system releasing ulipristal acetate: A randomized proof-of-concept study.

Contraception

Avec: Vivian Brache , Carolina Sales Vieira , Marlena Plagianos , Maud Lansiaux , Ruth Merkatz , Heather Sussman , Leila Cochon , Ana S Tejada , Narender Kumar , Daniel Loeven , Abi Santhosh Aprem , Alistair Rw Williams , Athilakshmi Kannan , Indrani C Bagchi , Regine Sitruk-Ware

Dimethandrolone, a Potential Male Contraceptive Pill, is Primarily Metabolized by the Highly Polymorphic UDP-Glucuronosyltransferase 2B17 Enzyme in Human Intestine and Liver.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Sheena Sharma , Deepak Ahire , Abdul Basit , Maria Lajoie , Christina Wang , Min S Lee , John K Amory , Dilip K Singh , Scott Heyward , Bhagwat Prasad

Emergency contraception for individuals weighing 80kg or greater: a randomized trial of 30 mg ulipristal acetate and 1.5 mg or 3.0 mg levonorgestrel.

Contraception

Avec: Alison Edelman , Jeffrey T Jensen , Jill Brown , Michael Thomas , David F Archer , Courtney A Schreiber , Stephanie Teal , Carolyn Westhoff , Clint Dart ,

Combined nestorone-testosterone gel suppresses serum gonadotropins to concentrations associated with effective hormonal contraception in men.

Andrology

Avec: B D Anawalt , M Y Roth , J Ceponis , V Surampudi , J K Amory , R S Swerdloff , P Y Liu , C Dart , W J Bremner , R Sitruk-Ware , N Kumar , D L Blithe , S T Page , C Wang

Acceptability of the Woman's Condom in a phase III multicenter open-label study.

Contraception

Avec: Beatrice A Chen , Gitonga R Muraguri , Audrey A Lance , Bruce R Carr , Jeffrey T Jensen , Thomas D Kimble , Amitasrigowri S Murthy , Courtney A Schreiber , Michael A Thomas , Terri L Walsh , Carolyn Westhoff , Anne E Burke

Safety and Pharmacokinetics of Single-Dose Novel Oral Androgen 11β-Methyl-19-Nortestosterone-17β-Dodecylcarbonate in Men.

The Journal of clinical endocrinology and metabolism

Avec: Sherry Wu , Fiona Yuen , Ronald S Swerdloff , Youngju Pak , Arthi Thirumalai , Peter Y Liu , John K Amory , Feng Bai , Laura Hull , Bradley D Anawalt , Toufan Parman , Kyuri Kim , Min S Lee , William J Bremner , Stephanie T Page , Christina Wang

Continuation rates of two different-sized copper intrauterine devices among nulliparous women: Interim 12-month results of a single-blind, randomised, multicentre trial.

EClinicalMedicine

Avec: David Hubacher , Courtney A Schreiber , David K Turok , Jeffrey T Jensen , Mitchell D Creinin , Kavita Nanda , Katharine O'Connell White , Ila Dayananda , Stephanie B Teal , Pai-Lien Chen , Beatrice A Chen , Alisa B Goldberg , Jennifer L Kerns , Clint Dart , Anita L Nelson , Michael A Thomas , David F Archer , Jill E Brown , Paula M Castaño , Anne E Burke , Bliss Kaneshiro ,

Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a phase 1 clinical trial: learning from users to improve acceptability.

Frontiers in reproductive health

Avec: Mary Kate Shapley-Quinn , Mei Song , Beatrice A Chen , Brid Devlin , Ellen Luecke , Jill Brown , Sharon L Achilles , Ariane van der Straten

Contraceptive efficacy: Determining the threshold for effective suppression based on sperm concentration, motility, and morphology.

Andrology

Avec: Christina Wang , Christopher L R Barratt ,

Development of new hormonal male contraception for the couple.

Andrology

Avec: Jeffrey M Kroopnick , Min S Lee ,

Dose-finding study of a 90-day contraceptive vaginal ring releasing estradiol and segesterone acetate.

Contraception

Avec: Melissa J Chen , Mitchell D Creinin , David K Turok , David F Archer , Kurt T Barnhart , Carolyn L Westhoff , Michael A Thomas , Jeffrey T Jensen , Bruce Variano , Regine Sitruk-Ware , Anita Shanker , Jill Long ,

Effects of 28 Days of Oral Dimethandrolone Undecanoate in Healthy Men: A Prototype Male Pill.

The Journal of clinical endocrinology and metabolism

Avec: Arthi Thirumalai , Jonas Ceponis , John K Amory , Ronald Swerdloff , Vijaya Surampudi , Peter Y Liu , William J Bremner , Eric Harvey , Min S Lee , Laura Hull , Christina Wang , Stephanie T Page

Preventing secondary exposure to women from men applying a novel nestorone/testosterone contraceptive gel.

Andrology

Avec: F Yuen , S Wu , A Thirumalai , R S Swerdloff , S T Page , P Y Liu , C Dart , H Wu , D L Blithe , R Sitruk-Ware , J Long , F Bai , L Hull , W J Bremner , B D Anawalt , C Wang

Efficacy of the 1-year (13-cycle) segesterone acetate and ethinylestradiol contraceptive vaginal system: results of two multicentre, open-label, single-arm, phase 3 trials.

The Lancet. Global health

Avec: David F Archer , Ruth B Merkatz , Luis Bahamondes , Carolyn L Westhoff , Philip Darney , Dan Apter , Jeffrey T Jensen , Vivian Brache , Anita L Nelson , Erika Banks , György Bártfai , David J Portman , Marlena Plagianos , Clint Dart , Narender Kumar , George W Creasy , Regine Sitruk-Ware ,

Update on Novel Hormonal and Nonhormonal Male Contraceptive Development.

The Journal of clinical endocrinology and metabolism

Avec: Jill E Long , Min S Lee ,

Male contraception is coming: Who do men want to prescribe their birth control?

Contraception

Avec: Tamar Jacobsohn , Brian T Nguyen , Jill E Brown , Arthi Thirumalai , Michael Massone , Stephanie T Page , Christina Wang , Jeffrey Kroopnick ,

Evaluation of ovulation and safety outcomes in a multi-center randomized trial of three 84 day ulipristal acetate regimens.

Contraception

Avec: Carolyn L Westhoff , David F Archer , Kurt Barnhart , Philip Darney , Melissa Gilliam , Jeffrey Jensen , Anita Nelson , Stephanie Teal , Michael Thomas , Jack Hu , Jill Brown ,

Design of an international male contraceptive efficacy trial using a self-administered daily transdermal gel containing testosterone and segesterone acetate (Nestorone).

Contraception

Avec: John K Amory , Regine Sitruk-Ware , Ronald S Swerdloff , William J Bremner , Clint Dart , Peter Y Liu , Arthi Thirumalai , Brian T Nguyen , Bradley D Anawalt , Min S Lee , Stephanie T Page , Christina Wang

Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17.

Pharmaceutics

Avec: Namrata Bachhav , Dilip Kumar Singh , Min S Lee , Bhagwat Prasad

Dimethandrolone Undecanoate, a Novel, Nonaromatizable Androgen, Increases P1NP in Healthy Men Over 28 Days.

The Journal of clinical endocrinology and metabolism

Avec: Arthi Thirumalai , Fiona Yuen , John K Amory , Andrew N Hoofnagle , Ronald S Swerdloff , Peter Y Liu , Jill E Long , Christina Wang , Stephanie T Page

Bleeding profile associated with 1-year use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system: pooled analysis from Phase 3 trials.

Contraception

Avec: Carolina Sales Vieira , Ian S Fraser , Marlena G Plagianos , Anne E Burke , Carolyn L Westhoff , Jeffrey Jensen , Vivian Brache , Luis Bahamondes , Ruth Merkatz , Regine Sitruk-Ware ,

Daily Oral Administration of the Novel Androgen 11β-MNTDC Markedly Suppresses Serum Gonadotropins in Healthy Men.

The Journal of clinical endocrinology and metabolism

Avec: Fiona Yuen , Arthi Thirumalai , Cindy Pham , Ronald S Swerdloff , Bradley D Anawalt , Peter Y Liu , John K Amory , William J Bremner , Clint Dart , Hongsheng Wu , Laura Hull , Jill Long , Christina Wang , Stephanie T Page

Simultaneous assay of segesterone acetate (Nestorone®), estradiol, progesterone, and estrone in human serum by LC-MS/MS.

Contraception

Avec: David W Erikson , Steven W Blue , Kristopher M Fecteau , Alison B Edelman , Jeffrey T Jensen ,

Acceptability of the oral hormonal male contraceptive prototype, 11β-methyl-19-nortestosterone dodecylcarbonate (11β-MNTDC), in a 28-day placebo-controlled trial.

Contraception

Avec: Brian T Nguyen , Fiona Yuen , Maritza Farrant , Arthi Thirumalai , Frances Fernando , John K Amory , Ronald S Swerdloff , Bradley D Anawalt , Jill E Long , Peter Y Liu , Stephanie T Page , Christina Wang

Contraceptive and Infertility Target DataBase: a contraceptive drug development tool for targeting and analysis of human reproductive specific tissues†.

Biology of reproduction

Avec: Subarna Sinha , Merrill Knapp , John Pywtorak , Greg McCain , Kenneth Wingerden , Colin VanDervoort , J Mark Gondek , Peter Madrid , Toufan Parman , Stephen Gerrard , Jill E Long , Stuart Moss , Min S Lee

Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings.

PloS one

Avec: Sharon L Achilles , Clifton W Kelly , Craig J Hoesley , Jill Brown , Barbra A Richardson , Brid Devlin , Craig W Hendrix , Samuel M Poloyac , Mark A Marzinke , Holly Gundacker , Devika Singh , Jeanna M Piper , Sherri Johnson , John Steytler , Beatrice A Chen , Auteur inconnu

Use of serum evaluation of contraceptive and ovarian hormones to assess reduced risk of pregnancy among women presenting for emergency contraception in a multicenter clinical trial.

Contraception

Avec: Jeffrey T Jensen , Alison Edelman , Carolyn L Westhoff , Coutney A Schreiber , David F Archer , Stephanie Teal , Michael Thomas , Jill Brown ,

Male contraception development: monitoring effective spermatogenesis suppression utilizing a user-controlled sperm concentration test compared with standard semen analysis.

Fertility and sterility

Avec: Yanhe Lue , Ronald Swerdloff , Youngju Pak , Brian T Nguyen , Fiona Yuen , Peter Y Liu , Christina Wang

Novel Progestogenic androgens for male contraception: design, synthesis and activity of C7 α-substituted testosterone.

Biology of reproduction

Avec: Min S Lee , Deborah I Bunin , Anna M Furimsky , Donna Nguyen , Toufan Parman , Kyuri Kim , Linda Rausch , Ming-Teh Lin , Pranab Gupta , Jill E Brown , Jeffrey M Kroopnick ,

Réseau de co-auteurs

Christina Wang 12 collaborations

Min S Lee 10 collaborations

Arthi Thirumalai 9 collaborations

Peter Y Liu 9 collaborations

Stephanie T Page 9 collaborations

Jeffrey T Jensen 8 collaborations

John K Amory 8 collaborations

David F Archer 7 collaborations

Fiona Yuen 7 collaborations

Ronald S Swerdloff 7 collaborations

Jill E Long 6 collaborations

Jill Brown 6 collaborations

Carolyn L Westhoff 6 collaborations

Regine Sitruk-Ware 6 collaborations

Brian T Nguyen 5 collaborations

Bradley D Anawalt 5 collaborations

William J Bremner 5 collaborations

Clint Dart 5 collaborations

Michael A Thomas 4 collaborations

Laura Hull 4 collaborations

Courtney A Schreiber 4 collaborations

Beatrice A Chen 4 collaborations

Anita L Nelson 3 collaborations

Youngju Pak 3 collaborations

Mitchell D Creinin 3 collaborations

Vivian Brache 3 collaborations

Michael Thomas 3 collaborations

Stephanie Teal 3 collaborations

Anne E Burke 3 collaborations

Toufan Parman 3 collaborations

Jill E Brown 3 collaborations

Terri L Walsh 2 collaborations

Kurt T Barnhart 2 collaborations

Hongsheng Wu 2 collaborations

David Hubacher 2 collaborations

Bliss Kaneshiro 2 collaborations

Kavita Nanda 2 collaborations

None None 2 collaborations

Carolina Sales Vieira 2 collaborations

Marlena Plagianos 2 collaborations

Ruth Merkatz 2 collaborations

Narender Kumar 2 collaborations

Bhagwat Prasad 2 collaborations

Alison Edelman 2 collaborations

Carolyn Westhoff 2 collaborations

B D Anawalt 2 collaborations

R S Swerdloff 2 collaborations

P Y Liu 2 collaborations

C Dart 2 collaborations

W J Bremner 2 collaborations

R Sitruk-Ware 2 collaborations

D L Blithe 2 collaborations

S T Page 2 collaborations

C Wang 2 collaborations

Kyuri Kim 2 collaborations

David K Turok 2 collaborations

Brid Devlin 2 collaborations

Sharon L Achilles 2 collaborations

Jeffrey M Kroopnick 2 collaborations

Jill Long 2 collaborations

Ronald Swerdloff 2 collaborations

Luis Bahamondes 2 collaborations

Philip Darney 2 collaborations

Jeffrey Jensen 2 collaborations

Margaret C Snead 1 collaboration

Breione J St Claire 1 collaboration

Jill L Schwartz 1 collaboration

Christine K Mauck 1 collaboration

Ron G Frezieres 1 collaboration

Livia S Wan 1 collaboration

Mark A Weaver 1 collaboration

Frances A Fernando 1 collaboration

Rachelle Bross 1 collaboration

Maritza T Farrant 1 collaboration

Molly Tiedeken 1 collaboration

Adi Cohen 1 collaboration

Serge Cremers 1 collaboration

Maud Lansiaux 1 collaboration

Heather Sussman 1 collaboration

Leila Cochon 1 collaboration

Ana S Tejada 1 collaboration

Daniel Loeven 1 collaboration

Abi Santhosh Aprem 1 collaboration

Alistair Rw Williams 1 collaboration

Athilakshmi Kannan 1 collaboration

Indrani C Bagchi 1 collaboration

Sheena Sharma 1 collaboration

Deepak Ahire 1 collaboration

Abdul Basit 1 collaboration

Maria Lajoie 1 collaboration

Dilip K Singh 1 collaboration

Scott Heyward 1 collaboration

M Y Roth 1 collaboration

J Ceponis 1 collaboration

V Surampudi 1 collaboration

J K Amory 1 collaboration

N Kumar 1 collaboration

Gitonga R Muraguri 1 collaboration

Audrey A Lance 1 collaboration

Bruce R Carr 1 collaboration

Thomas D Kimble 1 collaboration

Amitasrigowri S Murthy 1 collaboration

Sherry Wu 1 collaboration

Feng Bai 1 collaboration

Katharine O'Connell White 1 collaboration

Ila Dayananda 1 collaboration

Stephanie B Teal 1 collaboration

Pai-Lien Chen 1 collaboration

Alisa B Goldberg 1 collaboration

Jennifer L Kerns 1 collaboration

Paula M Castaño 1 collaboration

Mary Kate Shapley-Quinn 1 collaboration

Mei Song 1 collaboration

Ellen Luecke 1 collaboration

Ariane van der Straten 1 collaboration

Christopher L R Barratt 1 collaboration

Melissa J Chen 1 collaboration

Bruce Variano 1 collaboration

Anita Shanker 1 collaboration

Jonas Ceponis 1 collaboration

Vijaya Surampudi 1 collaboration

Eric Harvey 1 collaboration

F Yuen 1 collaboration

S Wu 1 collaboration

A Thirumalai 1 collaboration

H Wu 1 collaboration

J Long 1 collaboration

F Bai 1 collaboration

L Hull 1 collaboration

Ruth B Merkatz 1 collaboration

Dan Apter 1 collaboration

Erika Banks 1 collaboration

György Bártfai 1 collaboration

David J Portman 1 collaboration

George W Creasy 1 collaboration

Tamar Jacobsohn 1 collaboration

Michael Massone 1 collaboration

Jeffrey Kroopnick 1 collaboration

Kurt Barnhart 1 collaboration

Melissa Gilliam 1 collaboration

Anita Nelson 1 collaboration

Jack Hu 1 collaboration

Namrata Bachhav 1 collaboration

Dilip Kumar Singh 1 collaboration

Andrew N Hoofnagle 1 collaboration

Ian S Fraser 1 collaboration

Marlena G Plagianos 1 collaboration

Cindy Pham 1 collaboration

David W Erikson 1 collaboration

Steven W Blue 1 collaboration

Kristopher M Fecteau 1 collaboration

Alison B Edelman 1 collaboration

Maritza Farrant 1 collaboration

Frances Fernando 1 collaboration

Subarna Sinha 1 collaboration

Merrill Knapp 1 collaboration

John Pywtorak 1 collaboration

Greg McCain 1 collaboration

Kenneth Wingerden 1 collaboration

Colin VanDervoort 1 collaboration

J Mark Gondek 1 collaboration

Peter Madrid 1 collaboration

Stephen Gerrard 1 collaboration

Stuart Moss 1 collaboration

Clifton W Kelly 1 collaboration

Craig J Hoesley 1 collaboration

Barbra A Richardson 1 collaboration

Craig W Hendrix 1 collaboration

Samuel M Poloyac 1 collaboration

Mark A Marzinke 1 collaboration

Holly Gundacker 1 collaboration

Devika Singh 1 collaboration

Jeanna M Piper 1 collaboration

Sherri Johnson 1 collaboration

John Steytler 1 collaboration

Coutney A Schreiber 1 collaboration

Yanhe Lue 1 collaboration

Deborah I Bunin 1 collaboration

Anna M Furimsky 1 collaboration

Donna Nguyen 1 collaboration

Linda Rausch 1 collaboration

Ming-Teh Lin 1 collaboration

Pranab Gupta 1 collaboration