David A Candito

Affiliations

Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Pharmacokinetics and Drug Metabolism, Oncology Early Discovery, Merck & Co., Inc., Boston, Massachusetts 02115, United States.

Publications (3)

Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds.

ACS medicinal chemistry letters

Avec: Brandon A Vara , Samuel M Levi , Abdelghani Achab , Xavier Fradera , Charles A Lesburg , Shuhei Kawamura , Brian M Lacey , Jongwon Lim , Joey L Methot , Zangwei Xu , Haiyan Xu , Dustin M Smith , Jennifer A Piesvaux , J Richard Miller , Mark Bittinger , Sheila H Ranganath , David J Bennett , Erin F DiMauro , Alexander Pasternak

Development of a Flexible and Robust Synthesis of Tetrahydrofuro[3,4-

The Journal of organic chemistry

Avec: Yingchun Ye , Ryan V Quiroz , Michael H Reutershan , David Witter , Surendra B Gadamsetty , Hongming Li , Josep Saurí , Sebastian E Schneider , Yu-Hong Lam , Rachel L Palte

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1

Journal of medicinal chemistry

Avec: Vladimir Simov , Anmol Gulati , Solomon Kattar , Ryan W Chau , Blair T Lapointe , Joey L Methot , Duane E DeMong , Thomas H Graham , Ravi Kurukulasuriya , Mitchell H Keylor , Ling Tong , Gregori J Morriello , John J Acton , Barbara Pio , Weiguo Liu , Jack D Scott , Michael J Ardolino , Theodore A Martinot , Matthew L Maddess , Xin Yan , Hakan Gunaydin , Rachel L Palte , Spencer E McMinn , Lisa Nogle , Hongshi Yu , Ellen C Minnihan , Charles A Lesburg , Ping Liu , Jing Su , Laxminarayan G Hegde , Lily Y Moy , Janice D Woodhouse , Robert Faltus , Tina Xiong , Paul Ciaccio , Jennifer A Piesvaux , Karin M Otte , Matthew E Kennedy , David Jonathan Bennett , Erin F DiMauro , Matthew J Fell , Santhosh Neelamkavil , Harold B Wood , Peter H Fuller , J Michael Ellis

Réseau de co-auteurs

Charles A Lesburg 2 collaborations

Joey L Methot 2 collaborations

Jennifer A Piesvaux 2 collaborations

Erin F DiMauro 2 collaborations

Rachel L Palte 2 collaborations

Brandon A Vara 1 collaboration

Samuel M Levi 1 collaboration

Abdelghani Achab 1 collaboration

Xavier Fradera 1 collaboration

Shuhei Kawamura 1 collaboration

Brian M Lacey 1 collaboration

Jongwon Lim 1 collaboration

Zangwei Xu 1 collaboration

Haiyan Xu 1 collaboration

Dustin M Smith 1 collaboration

J Richard Miller 1 collaboration

Mark Bittinger 1 collaboration

Sheila H Ranganath 1 collaboration

David J Bennett 1 collaboration

Alexander Pasternak 1 collaboration

Yingchun Ye 1 collaboration

Ryan V Quiroz 1 collaboration

Michael H Reutershan 1 collaboration

David Witter 1 collaboration

Surendra B Gadamsetty 1 collaboration

Hongming Li 1 collaboration

Josep Saurí 1 collaboration

Sebastian E Schneider 1 collaboration

Yu-Hong Lam 1 collaboration

Vladimir Simov 1 collaboration

Anmol Gulati 1 collaboration

Solomon Kattar 1 collaboration

Ryan W Chau 1 collaboration

Blair T Lapointe 1 collaboration

Duane E DeMong 1 collaboration

Thomas H Graham 1 collaboration

Ravi Kurukulasuriya 1 collaboration

Mitchell H Keylor 1 collaboration

Ling Tong 1 collaboration

Gregori J Morriello 1 collaboration

John J Acton 1 collaboration

Barbara Pio 1 collaboration

Weiguo Liu 1 collaboration

Jack D Scott 1 collaboration

Michael J Ardolino 1 collaboration

Theodore A Martinot 1 collaboration

Matthew L Maddess 1 collaboration

Xin Yan 1 collaboration

Hakan Gunaydin 1 collaboration

Spencer E McMinn 1 collaboration

Lisa Nogle 1 collaboration

Hongshi Yu 1 collaboration

Ellen C Minnihan 1 collaboration

Ping Liu 1 collaboration

Jing Su 1 collaboration

Laxminarayan G Hegde 1 collaboration

Lily Y Moy 1 collaboration

Janice D Woodhouse 1 collaboration

Robert Faltus 1 collaboration

Tina Xiong 1 collaboration

Paul Ciaccio 1 collaboration

Karin M Otte 1 collaboration

Matthew E Kennedy 1 collaboration

David Jonathan Bennett 1 collaboration

Matthew J Fell 1 collaboration

Santhosh Neelamkavil 1 collaboration

Harold B Wood 1 collaboration

Peter H Fuller 1 collaboration

J Michael Ellis 1 collaboration