Craig J Schofield

Publications (12)

HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Pascale Sulser , Christina Pickel , Julia Günter , Thomas M Leissing , Daniel Crean , Christopher J Schofield , Roland H Wenger , Carsten C Scholz

Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells.

Communications biology

Avec: John Walsby-Tickle , Joan Gannon , Ingvild Hvinden , Chiara Bardella , Martine I Abboud , Areesha Nazeer , David Hauton , Elisabete Pires , Tom Cadoux-Hudson , Christopher J Schofield , James S O McCullagh

Reducing Agent-Mediated Nonenzymatic Conversion of 2-Oxoglutarate to Succinate: Implications for Oxygenase Assays.

Chembiochem : a European journal of chemical biology

Avec: Amjad Khan , Christopher J Schofield , Timothy D W Claridge

In vitro efficacy of imipenem-relebactam and cefepime-AAI101 against a global collection of ESBL-positive and carbapenemase-producing Enterobacteriaceae.

International journal of antimicrobial agents

Avec: Lucas Tselepis , Gareth W Langley , Ali F Aboklaish , Emma Widlake , Dana E Jackson , Timothy R Walsh , Chris J Schofield , Jürgen Brem , Jonathan M Tyrrell

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates.

eLife

Avec: Matthew E Cockman , Kerstin Lippl , Ya-Min Tian , Hamish B Pegg , William D Figg , Martine I Abboud , Raphael Heilig , Roman Fischer , Johanna Myllyharju , Christopher J Schofield , Peter J Ratcliffe

Molecular Basis of Class A β-Lactamase Inhibition by Relebactam.

Antimicrobial agents and chemotherapy

Avec: Catherine L Tooke , Philip Hinchliffe , Pauline A Lang , Adrian J Mulholland , Jürgen Brem , Christopher J Schofield , James Spencer

A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy.

Metabolites

Avec: Xin Shen , Natalie L Voets , Sarah J Larkin , Nick de Pennington , Puneet Plaha , Richard Stacey , James S O McCullagh , Christopher J Schofield , Stuart Clare , Peter Jezzard , Tom Cadoux-Hudson , Olaf Ansorge , Uzay E Emir

Conformational flexibility influences structure-function relationships in nucleic acid N-methyl demethylases.

Organic & biomolecular chemistry

Avec: Sodiq O Waheed , Rajeev Ramanan , Shobhit S Chaturvedi , Jon Ainsley , Martin Evison , Jennifer M Ames , Christopher J Schofield , Christo Z Christov , Tatyana G Karabencheva-Christova

Will morphing boron-based inhibitors beat the β-lactamases?

Current opinion in chemical biology

Avec: Alen Krajnc , Pauline A Lang , Tharindi D Panduwawala , Jürgen Brem , Christopher J Schofield

Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.

The Journal of biological chemistry

Avec: Md Saiful Islam , Michael A McDonough , Rasheduzzaman Chowdhury , Joseph Gault , Amjad Khan , Elisabete Pires , Christopher J Schofield

A Fluorescent Benzo[g]isoquinoline-Based HIF Prolyl Hydroxylase Inhibitor for Cellular Imaging.

ChemMedChem

Avec: Marleen Mayer , Kerstin Fey , Eva Heinze , Christian R Wick , Martine I Abboud , Tzu-Lan Yeh , Anthony Tumber , Nicole Orth , Gunnar Schley , Björn Buchholz , Timothy Clark , Christopher J Schofield , Carsten Willam , Nicolai Burzlaff

Structures of

Molecular pharmacology

Avec: Zuokun Lu , Han Wang , Aili Zhang , Xiang Liu , Weihong Zhou , Cheng Yang , Luke Guddat , Haitao Yang , Christopher J Schofield , Zihe Rao

Réseau de co-auteurs

Christopher J Schofield 11 collaborations

Martine I Abboud 3 collaborations

Jürgen Brem 3 collaborations

Elisabete Pires 2 collaborations

Tom Cadoux-Hudson 2 collaborations

James S O McCullagh 2 collaborations

Amjad Khan 2 collaborations

Pauline A Lang 2 collaborations

Pascale Sulser 1 collaboration

Christina Pickel 1 collaboration

Julia Günter 1 collaboration

Thomas M Leissing 1 collaboration

Daniel Crean 1 collaboration

Roland H Wenger 1 collaboration

Carsten C Scholz 1 collaboration

John Walsby-Tickle 1 collaboration

Joan Gannon 1 collaboration

Ingvild Hvinden 1 collaboration

Chiara Bardella 1 collaboration

Areesha Nazeer 1 collaboration

David Hauton 1 collaboration

Timothy D W Claridge 1 collaboration

Lucas Tselepis 1 collaboration

Gareth W Langley 1 collaboration

Ali F Aboklaish 1 collaboration

Emma Widlake 1 collaboration

Dana E Jackson 1 collaboration

Timothy R Walsh 1 collaboration

Chris J Schofield 1 collaboration

Jonathan M Tyrrell 1 collaboration

Matthew E Cockman 1 collaboration

Kerstin Lippl 1 collaboration

Ya-Min Tian 1 collaboration

Hamish B Pegg 1 collaboration

William D Figg 1 collaboration

Raphael Heilig 1 collaboration

Roman Fischer 1 collaboration

Johanna Myllyharju 1 collaboration

Peter J Ratcliffe 1 collaboration

Catherine L Tooke 1 collaboration

Philip Hinchliffe 1 collaboration

Adrian J Mulholland 1 collaboration

James Spencer 1 collaboration

Xin Shen 1 collaboration

Natalie L Voets 1 collaboration

Sarah J Larkin 1 collaboration

Nick de Pennington 1 collaboration

Puneet Plaha 1 collaboration

Richard Stacey 1 collaboration

Stuart Clare 1 collaboration

Peter Jezzard 1 collaboration

Olaf Ansorge 1 collaboration

Uzay E Emir 1 collaboration

Sodiq O Waheed 1 collaboration

Rajeev Ramanan 1 collaboration

Shobhit S Chaturvedi 1 collaboration

Jon Ainsley 1 collaboration

Martin Evison 1 collaboration

Jennifer M Ames 1 collaboration

Christo Z Christov 1 collaboration

Tatyana G Karabencheva-Christova 1 collaboration

Alen Krajnc 1 collaboration

Tharindi D Panduwawala 1 collaboration

Md Saiful Islam 1 collaboration

Michael A McDonough 1 collaboration

Rasheduzzaman Chowdhury 1 collaboration

Joseph Gault 1 collaboration

Marleen Mayer 1 collaboration

Kerstin Fey 1 collaboration

Eva Heinze 1 collaboration

Christian R Wick 1 collaboration

Tzu-Lan Yeh 1 collaboration

Anthony Tumber 1 collaboration

Nicole Orth 1 collaboration

Gunnar Schley 1 collaboration

Björn Buchholz 1 collaboration

Timothy Clark 1 collaboration

Carsten Willam 1 collaboration

Nicolai Burzlaff 1 collaboration

Zuokun Lu 1 collaboration

Han Wang 1 collaboration

Aili Zhang 1 collaboration

Xiang Liu 1 collaboration

Weihong Zhou 1 collaboration

Cheng Yang 1 collaboration

Luke Guddat 1 collaboration

Haitao Yang 1 collaboration

Zihe Rao 1 collaboration