Claudia Spits

Affiliations

Research Group Reproduction and Genetics, Vrije Universiteit Brussel, Brussel, Belgium.

Publications (22)

Detection of Heteroplasmic Variants in the Mitochondrial Genome through Massive Parallel Sequencing.

Bio-protocol

Avec: Joke Mertens , Filippo Zambelli , Dorien Daneels , Ben Caljon , Karen Sermon ,

Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally.

Human molecular genetics

Avec: Joke Mertens , Marius Regin , Neelke De Munck , Edouard Couvreu de Deckersberg , Florence Belva , Karen Sermon , Herman Tournaye , Christophe Blockeel , Hilde Van de Velde ,

ESHRE survey results and good practice recommendations on managing chromosomal mosaicism.

Human reproduction open

Avec: Auteur inconnu , Martine De Rycke , Antonio Capalbo , Edith Coonen , Giovanni Coticchio , Francesco Fiorentino , Veerle Goossens , Saria Mcheik , Carmen Rubio , Karen Sermon , Ioannis Sfontouris , Joris Robert Vermeesch , Nathalie Vermeulen , Dagan Wells , Filippo Zambelli , Georgia Kakourou

ISSCR standards for the use of human stem cells in basic research.

Stem cell reports

Avec: Tenneille E Ludwig , Peter W Andrews , Ivana Barbaric , Nissim Benvenisty , Anita Bhattacharyya , Jeremy M Crook , Laurence M Daheron , Jonathan S Draper , Lyn E Healy , Meritxell Huch , Maneesha S Inamdar , Kim B Jensen , Andreas Kurtz , Madeline A Lancaster , Prisca Liberali , Matthias P Lutolf , Christine L Mummery , Martin F Pera , Yoji Sato , Noriko Shimasaki , Austin G Smith , Jihwan Song , Glyn Stacey , Christine A Wells , Tongbiao Zhao , Jack T Mosher

Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.

Stem cell reports

Avec: C Markouli , E Couvreu De Deckersberg , M Regin , H T Nguyen , F Zambelli , A Keller , D Dziedzicka , J De Kock , L Tilleman , F Van Nieuwerburgh , L Franceschini , K Sermon , M Geens , C Spits

Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing.

Biology open

Avec: Silvie Franck , Edouard Couvreu De Deckersberg , Jodi L Bubenik , Christina Markouli , Lise Barbé , Joke Allemeersch , Pierre Hilven , Geoffrey Duqué , Maurice S Swanson , Alexander Gheldof , Karen D Sermon

Gains of 20q11.21 in human pluripotent stem cells: Insights from cancer research.

Stem cell reports

Avec: Nuša Krivec , Manjusha S Ghosh ,

On the origins and fate of chromosomal abnormalities in human preimplantation embryos: an unsolved riddle.

Molecular human reproduction

Avec: Marius Regin , Karen Sermon

Association between sequence variants in the FSHR gene and reproductive outcomes following IVF in predicted normoresponders.

Reproductive biomedicine online

Avec: Ana Raquel Neves , Sandra Garcia , Lan Tn Vuong , Christophe Blockeel , Gemma Arroyo , Toan D Pham , Tuong M Ho , Herman Tournaye , Nikolaos P Polyzos

Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight.

Nature communications

Avec: Joke Mertens , Florence Belva , Aafke P A van Montfoort , Marius Regin , Filippo Zambelli , Sara Seneca , Edouard Couvreu de Deckersberg , Maryse Bonduelle , Herman Tournaye , Katrien Stouffs , Kurt Barbé , Hubert J M Smeets , Hilde Van de Velde , Karen Sermon , Christophe Blockeel ,

The effect of polymorphisms in FSHR gene on late follicular phase progesterone and estradiol serum levels in predicted normoresponders.

Human reproduction (Oxford, England)

Avec: A R Neves , N L Vuong , C Blockeel , S Garcia , C Alviggi , C Spits , P Q M Ma , M T Ho , H Tournaye , N P Polyzos

The Additive Effect of Combinations of FSH Receptor Gene Variants in Ovarian Response to Stimulation.

Reproductive sciences (Thousand Oaks, Calif.)

Avec: Ana Raquel Neves , Sandra Garcia , Lan N Vuong , Christophe Blockeel , Nikolaos P Polyzos

Uncovering low-level mosaicism in human embryonic stem cells using high throughput single cell shallow sequencing.

Scientific reports

Avec: Alexander Keller , Laurentijn Tilleman , Dominika Dziedzicka , Filippo Zambelli , Karen Sermon , Filip Van Nieuwerburgh , Mieke Geens

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm.

Scientific reports

Avec: Dominika Dziedzicka , Mukul Tewary , Alexander Keller , Laurentijn Tilleman , Laura Prochazka , Joel Östblom , Edouard Couvreu De Deckersberg , Christina Markouli , Silvie Franck , Filip Van Nieuwerburgh , Peter W Zandstra , Karen Sermon , Mieke Geens

Sustained intrinsic WNT and BMP4 activation impairs hESC differentiation to definitive endoderm and drives the cells towards extra-embryonic mesoderm.

Scientific reports

Avec: C Markouli , E Couvreu De Deckersberg , D Dziedzicka , M Regin , S Franck , A Keller , A Gheldof , M Geens , K Sermon , C Spits

De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture.

Cells

Avec: Diana Al Delbany , Manjusha S Ghosh , Nuša Krivec , Anfien Huyghebaert , Marius Regin , Mai Chi Duong , Yingnan Lei , Karen Sermon , Catharina Olsen ,

The Impact of Acquired Genetic Abnormalities on the Clinical Translation of Human Pluripotent Stem Cells.

Cells

Avec: Alexander Keller ,

MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells.

Human molecular genetics

Avec: Silvie Franck , Lise Barbé , Simon Ardui , Yannick De Vlaeminck , Joke Allemeersch , Dominika Dziedzicka , Fien Vanroye , Pierre Hilven , Geoffrey Duqué , Joris R Vermeesch , Alexander Gheldof , Karen Sermon

The effect of polymorphisms in FSHR and FSHB genes on ovarian response: a prospective multicenter multinational study in Europe and Asia.

Human reproduction (Oxford, England)

Avec: Nikolaos P Polyzos , A R Neves , P Drakopoulos , C Spits , B Alvaro Mercadal , S Garcia , P Q M Ma , L H Le , M T Ho , J Mertens , D Stoop , H Tournaye , N L Vuong

Measuring Early Germ-Layer Specification Bias in Human Pluripotent Stem Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Alexander Keller , Nuša Krivec , Christina Markouli ,

The consequences of recurrent genetic and epigenetic variants in human pluripotent stem cells.

Cell stem cell

Avec: Peter W Andrews , Ivana Barbaric , Nissim Benvenisty , Jonathan S Draper , Tenneille Ludwig , Florian T Merkle , Yoji Sato , Glyn N Stacey , Haoyi Wang , Martin F Pera

SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss.

Stem cell reports

Avec: Yingnan Lei , Diana Al Delbany , Nuša Krivec , Marius Regin , Edouard Couvreu de Deckersberg , Charlotte Janssens , Manjusha Ghosh , Karen Sermon ,

Réseau de co-auteurs

Karen Sermon 10 collaborations

Marius Regin 5 collaborations

Filippo Zambelli 4 collaborations

Christophe Blockeel 4 collaborations

C Spits 4 collaborations

Nuša Krivec 4 collaborations

Alexander Keller 4 collaborations

Joke Mertens 3 collaborations

Edouard Couvreu de Deckersberg 3 collaborations

Herman Tournaye 3 collaborations

Silvie Franck 3 collaborations

Christina Markouli 3 collaborations

Nikolaos P Polyzos 3 collaborations

Dominika Dziedzicka 3 collaborations

Florence Belva 2 collaborations

Hilde Van de Velde 2 collaborations

Peter W Andrews 2 collaborations

Ivana Barbaric 2 collaborations

Nissim Benvenisty 2 collaborations

Jonathan S Draper 2 collaborations

Martin F Pera 2 collaborations

Yoji Sato 2 collaborations

C Markouli 2 collaborations

E Couvreu De Deckersberg 2 collaborations

M Regin 2 collaborations

A Keller 2 collaborations

D Dziedzicka 2 collaborations

K Sermon 2 collaborations

M Geens 2 collaborations

Edouard Couvreu De Deckersberg 2 collaborations

Lise Barbé 2 collaborations

Joke Allemeersch 2 collaborations

Pierre Hilven 2 collaborations

Geoffrey Duqué 2 collaborations

Alexander Gheldof 2 collaborations

Manjusha S Ghosh 2 collaborations

Ana Raquel Neves 2 collaborations

Sandra Garcia 2 collaborations

A R Neves 2 collaborations

N L Vuong 2 collaborations

S Garcia 2 collaborations

P Q M Ma 2 collaborations

M T Ho 2 collaborations

H Tournaye 2 collaborations

Laurentijn Tilleman 2 collaborations

Filip Van Nieuwerburgh 2 collaborations

Mieke Geens 2 collaborations

Diana Al Delbany 2 collaborations

Yingnan Lei 2 collaborations

Dorien Daneels 1 collaboration

Ben Caljon 1 collaboration

Neelke De Munck 1 collaboration

None None 1 collaboration

Martine De Rycke 1 collaboration

Antonio Capalbo 1 collaboration

Edith Coonen 1 collaboration

Giovanni Coticchio 1 collaboration

Francesco Fiorentino 1 collaboration

Veerle Goossens 1 collaboration

Saria Mcheik 1 collaboration

Carmen Rubio 1 collaboration

Ioannis Sfontouris 1 collaboration

Joris Robert Vermeesch 1 collaboration

Nathalie Vermeulen 1 collaboration

Dagan Wells 1 collaboration

Georgia Kakourou 1 collaboration

Tenneille E Ludwig 1 collaboration

Anita Bhattacharyya 1 collaboration

Jeremy M Crook 1 collaboration

Laurence M Daheron 1 collaboration

Lyn E Healy 1 collaboration

Meritxell Huch 1 collaboration

Maneesha S Inamdar 1 collaboration

Kim B Jensen 1 collaboration

Andreas Kurtz 1 collaboration

Madeline A Lancaster 1 collaboration

Prisca Liberali 1 collaboration

Matthias P Lutolf 1 collaboration

Christine L Mummery 1 collaboration

Noriko Shimasaki 1 collaboration

Austin G Smith 1 collaboration

Jihwan Song 1 collaboration

Glyn Stacey 1 collaboration

Christine A Wells 1 collaboration

Tongbiao Zhao 1 collaboration

Jack T Mosher 1 collaboration

H T Nguyen 1 collaboration

F Zambelli 1 collaboration

J De Kock 1 collaboration

L Tilleman 1 collaboration

F Van Nieuwerburgh 1 collaboration

L Franceschini 1 collaboration

Jodi L Bubenik 1 collaboration

Maurice S Swanson 1 collaboration

Karen D Sermon 1 collaboration

Lan Tn Vuong 1 collaboration

Gemma Arroyo 1 collaboration

Toan D Pham 1 collaboration

Tuong M Ho 1 collaboration

Aafke P A van Montfoort 1 collaboration

Sara Seneca 1 collaboration

Maryse Bonduelle 1 collaboration

Katrien Stouffs 1 collaboration

Kurt Barbé 1 collaboration

Hubert J M Smeets 1 collaboration

C Blockeel 1 collaboration

C Alviggi 1 collaboration

N P Polyzos 1 collaboration

Lan N Vuong 1 collaboration

Mukul Tewary 1 collaboration

Laura Prochazka 1 collaboration

Joel Östblom 1 collaboration

Peter W Zandstra 1 collaboration

S Franck 1 collaboration

A Gheldof 1 collaboration

Anfien Huyghebaert 1 collaboration

Mai Chi Duong 1 collaboration

Catharina Olsen 1 collaboration

Simon Ardui 1 collaboration

Yannick De Vlaeminck 1 collaboration

Fien Vanroye 1 collaboration

Joris R Vermeesch 1 collaboration

P Drakopoulos 1 collaboration

B Alvaro Mercadal 1 collaboration

L H Le 1 collaboration

J Mertens 1 collaboration

D Stoop 1 collaboration

Tenneille Ludwig 1 collaboration

Florian T Merkle 1 collaboration

Glyn N Stacey 1 collaboration

Haoyi Wang 1 collaboration

Charlotte Janssens 1 collaboration

Manjusha Ghosh 1 collaboration