Christopher J Bohlen

Affiliations

Department of Neuroscience, Genentech, South San Francisco, CA.

Publications (6)

Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9.

The Journal of experimental medicine

Avec: Emily C Freund , Jaclyn Y Lock , Jaehak Oh , Timurs Maculins , Lelia Delamarre , Benjamin Haley , Aditya Murthy

TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.

Cell reports

Avec: Seung-Hye Lee , Mitchell G Rezzonico , Brad A Friedman , Melanie H Huntley , William J Meilandt , Shristi Pandey , Ying-Jiun J Chen , Amy Easton , Zora Modrusan , David V Hansen , Morgan Sheng ,

Disease-associated oligodendrocyte responses across neurodegenerative diseases.

Cell reports

Avec: Shristi Pandey , Kimberle Shen , Seung-Hye Lee , Yun-An A Shen , Yuanyuan Wang , Marcos Otero-García , Natalya Kotova , Stephen T Vito , Benjamin I Laufer , Dwight F Newton , Mitchell G Rezzonico , Jesse E Hanson , Joshua S Kaminker , Tracy J Yuen , Brad A Friedman

Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease.

Nature neuroscience

Avec: Hu Zeng , Jiahao Huang , Haowen Zhou , William J Meilandt , Borislav Dejanovic , Yiming Zhou , Seung-Hye Lee , Jingyi Ren , Albert Liu , Zefang Tang , Hao Sheng , Jia Liu , Morgan Sheng , Xiao Wang

Systematic perturbation screens identify regulators of inflammatory macrophage states and a role for TNF mRNA m6A modification.

Nature genetics

Avec: Simone M Haag , Shiqi Xie , Celine Eidenschenk , Jean-Philippe Fortin , Marinella Callow , Mike Costa , Aaron Lun , Chris Cox , Sunny Z Wu , Rachana N Pradhan , Jaclyn Lock , Julia A Kuhn , Loryn Holokai , Minh Thai , Emily Freund , Ariane Nissenbaum , Mary Keir , Scott Martin , Kathryn Geiger-Schuller , Hussein A Hejase , Brian L Yaspan , Sandra Melo Carlos , Shannon J Turley , Aditya Murthy

Isolation and Culture of Microglia.

Current protocols in immunology

Avec: F Chris Bennett , Mariko L Bennett

Réseau de co-auteurs

Seung-Hye Lee 3 collaborations

Aditya Murthy 2 collaborations

Mitchell G Rezzonico 2 collaborations

Brad A Friedman 2 collaborations

William J Meilandt 2 collaborations

Shristi Pandey 2 collaborations

Morgan Sheng 2 collaborations

Emily C Freund 1 collaboration

Jaclyn Y Lock 1 collaboration

Jaehak Oh 1 collaboration

Timurs Maculins 1 collaboration

Lelia Delamarre 1 collaboration

Benjamin Haley 1 collaboration

Melanie H Huntley 1 collaboration

Ying-Jiun J Chen 1 collaboration

Amy Easton 1 collaboration

Zora Modrusan 1 collaboration

David V Hansen 1 collaboration

Kimberle Shen 1 collaboration

Yun-An A Shen 1 collaboration

Yuanyuan Wang 1 collaboration

Marcos Otero-García 1 collaboration

Natalya Kotova 1 collaboration

Stephen T Vito 1 collaboration

Benjamin I Laufer 1 collaboration

Dwight F Newton 1 collaboration

Jesse E Hanson 1 collaboration

Joshua S Kaminker 1 collaboration

Tracy J Yuen 1 collaboration

Hu Zeng 1 collaboration

Jiahao Huang 1 collaboration

Haowen Zhou 1 collaboration

Borislav Dejanovic 1 collaboration

Yiming Zhou 1 collaboration

Jingyi Ren 1 collaboration

Albert Liu 1 collaboration

Zefang Tang 1 collaboration

Hao Sheng 1 collaboration

Jia Liu 1 collaboration

Xiao Wang 1 collaboration

Simone M Haag 1 collaboration

Shiqi Xie 1 collaboration

Celine Eidenschenk 1 collaboration

Jean-Philippe Fortin 1 collaboration

Marinella Callow 1 collaboration

Mike Costa 1 collaboration

Aaron Lun 1 collaboration

Chris Cox 1 collaboration

Sunny Z Wu 1 collaboration

Rachana N Pradhan 1 collaboration

Jaclyn Lock 1 collaboration

Julia A Kuhn 1 collaboration

Loryn Holokai 1 collaboration

Minh Thai 1 collaboration

Emily Freund 1 collaboration

Ariane Nissenbaum 1 collaboration

Mary Keir 1 collaboration

Scott Martin 1 collaboration

Kathryn Geiger-Schuller 1 collaboration

Hussein A Hejase 1 collaboration

Brian L Yaspan 1 collaboration

Sandra Melo Carlos 1 collaboration

Shannon J Turley 1 collaboration

F Chris Bennett 1 collaboration

Mariko L Bennett 1 collaboration