Bruno Linclau

Affiliations

School of Chemistry, University of Southampton, Southampton SO17 1BJ, UK. bruno.linclau@soton.ac.uk.

ORCID: http://orcid.org/0000-0001-8762-0170

Publications (34)

Chemoenzymatic synthesis of 3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates.

Chemical communications (Cambridge, England)

Avec: Pablo Valverde , Jean-Baptiste Vendeville , Kristian Hollingsworth , Ashley P Mattey , Tessa Keenan , Harriet Chidwick , Helene Ledru , Kler Huonnic , Kun Huang , Mark E Light , Nicholas Turner , Jesús Jiménez-Barbero , M Carmen Galan , Martin A Fascione , Sabine Flitsch , W Bruce Turnbull ,

Synthesis of vicinal dideoxy-difluorinated galactoses.

Organic & biomolecular chemistry

Avec: Julien Malassis , Jean-Baptiste Vendeville , Qui-Hien Nguyen , Marie Boujon , Quentin Gaignard-Gaillard , Mark Light ,

Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs.

Journal of medicinal chemistry

Avec: Benjamin Jeffries , Zhong Wang , Hannah R Felstead , Jean-Yves Le Questel , James S Scott , Elisabetta Chiarparin , Jérôme Graton ,

Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library.

Chemical science

Avec: Tessa Keenan , Natasha E Hatton , Jack Porter , Jean-Baptiste Vendeville , David E Wheatley , Mattia Ghirardello , Alice J C Wahart , Sanaz Ahmadipour , Julia Walton , M Carmen Galan , Gavin J Miller , Martin A Fascione

Quantitative Analysis of 2D EXSY NMR Spectra of Strongly Coupled Spin Systems in Transmembrane Exchange.

Chembiochem : a European journal of chemical biology

Avec: Dmitry Shishmarev , Clement Q Fontenelle , Ilya Kuprov , Philip W Kuchel

Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.

The Journal of organic chemistry

Avec: Robert I Troup , Benjamin Jeffries , Raphael El-Bekri Saudain , Eleni Georgiou , Johanna Fish , James S Scott , Elisabetta Chiarparin , Charlene Fallan ,

Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands.

Chemical science

Avec: Sarah-Jane Richards , Tessa Keenan , Jean-Baptiste Vendeville , David E Wheatley , Harriet Chidwick , Darshita Budhadev , Claire E Council , Claire S Webster , Helene Ledru , Alexander N Baker , Marc Walker , M Carmen Galan , Martin A Fascione , Matthew I Gibson

Synthesis and Structural Characteristics of all Mono- and Difluorinated 4,6-Dideoxy-d-

The Journal of organic chemistry

Avec: David E Wheatley , Clement Q Fontenelle , Ramakrishna Kuppala , Robert Szpera , Edward L Briggs , Jean-Baptiste Vendeville , Neil J Wells , Mark E Light ,

Rapid Screening of Diverse Biotransformations for Enzyme Evolution.

JACS Au

Avec: Emily E Kempa , James L Galman , Fabio Parmeggiani , James R Marshall , Julien Malassis , Clement Q Fontenelle , Jean-Baptiste Vendeville , Simon J Charnock , Sabine L Flitsch , Nicholas J Turner , Perdita E Barran

Glycosylation of vicinal di- and trifluorinated glucose and galactose donors.

Chemical communications (Cambridge, England)

Avec: Kler Huonnic ,

Lipophilicity Modulations by Fluorination Correlate with Membrane Partitioning.

Angewandte Chemie (International ed. in English)

Avec: Zhong Wang , Hannah R Felstead , Robert I Troup , Philip T F Williamson

Synthesis and screening of a library of Lewis

Nature communications

Avec: Kristian Hollingsworth , Antonio Di Maio , Sarah-Jane Richards , Jean-Baptiste Vendeville , David E Wheatley , Claire E Council , Tessa Keenan , Hélène Ledru , Harriet Chidwick , Kun Huang , Fabio Parmeggiani , Andrea Marchesi , Wengang Chai , Ryan McBerney , Tomasz P Kamiński , Matthew R Balmforth , Alexandra Tamasanu , James D Finnigan , Carl Young , Stuart L Warriner , Michael E Webb , Martin A Fascione , Sabine Flitsch , M Carmen Galan , Ten Feizi , Matthew I Gibson , Yan Liu , W Bruce Turnbull ,

Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives.

Chemical Society reviews

Avec: Ana Ardá , Niels-Christian Reichardt , Matthieu Sollogoub , Luca Unione , Stéphane P Vincent , Jesús Jiménez-Barbero

Unraveling Sugar Binding Modes to DC-SIGN by Employing Fluorinated Carbohydrates.

Molecules (Basel, Switzerland)

Avec: J Daniel Martínez , Pablo Valverde , Sandra Delgado , Cecilia Romanò , Niels C Reichardt , Stefan Oscarson , Ana Ardá , Jesús Jiménez-Barbero , F Javier Cañada

Molecular Insights into DC-SIGN Binding to Self-Antigens: The Interaction with the Blood Group A/B Antigens.

ACS chemical biology

Avec: Pablo Valverde , Sandra Delgado , J Daniel Martínez , Jean-Baptiste Vendeville , Julien Malassis , Niels-Christian Reichardt , Francisco Javier Cañada , Jesús Jiménez-Barbero , Ana Ardá

Synthesis of 2,3,4-Trideoxy-2,3,4-trifluoroglucose.

The Journal of organic chemistry

Avec: Lucas Quiquempoix , Zhong Wang , Jérôme Graton , Peter G Latchem , Mark Light , Jean-Yves Le Questel ,

3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-α-GalCer analogues: Synthesis and biological evaluation on human iNKT cells stimulation.

European journal of medicinal chemistry

Avec: Samuel Golten , Allan Patinec , Katy Akoumany , Jézabel Rocher , Jérôme Graton , Denis Jacquemin , Jean-Yves Le Questel , Arnaud Tessier , Jacques Lebreton , Virginie Blot , Muriel Pipelier , Jean-Yves Douillard , Jacques Le Pendu , Didier Dubreuil

Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups.

Beilstein journal of organic chemistry

Avec: Benjamin Jeffries , Zhong Wang , Robert I Troup , Anaïs Goupille , Jean-Yves Le Questel , Charlene Fallan , James S Scott , Elisabetta Chiarparin , Jérôme Graton ,

Fluorine NMR study of proline-rich sequences using fluoroprolines.

Magnetic resonance (Gottingen, Germany)

Avec: Davy Sinnaeve , Abir Ben Bouzayene , Emile Ottoy , Gert-Jan Hofman , Eva Erdmann , Ilya Kuprov , José C Martins , Vladimir Torbeev , Bruno Kieffer

Obtaining Pure

The Journal of organic chemistry

Avec: Gabija Poškaitė , David E Wheatley , Neil Wells , Davy Sinnaeve

Molecular dynamics and NMR reveal the coexistence of H-bond-assisted and through-space

Organic & biomolecular chemistry

Avec: Cassia Chiari , Patrick R Batista , Renan V Viesser , Leonardo A Schenberg , Lucas C Ducati , Cláudio F Tormena

Conformational Analysis of 1,3-Difluorinated Alkanes.

The Journal of organic chemistry

Avec: William G Poole , Florent Peron , Stephen J Fox , Neil Wells , Chris-Kriton Skylaris , Jonathan W Essex , Ilya Kuprov ,

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.

Cell chemical biology

Avec: Tessa Keenan , Fabio Parmeggiani , Julien Malassis , Clement Q Fontenelle , Jean-Baptiste Vendeville , Wendy Offen , Peter Both , Kun Huang , Andrea Marchesi , Alex Heyam , Carl Young , Simon J Charnock , Gideon J Davies , Sabine L Flitsch , Martin A Fascione

Enzymatic glycosylation involving fluorinated carbohydrates.

Organic & biomolecular chemistry

Avec: Claire E Council , Kelly J Kilpin , Jessica S Gusthart , Sarah A Allman , Seung Seo Lee

Cubane Electrochemistry: Direct Conversion of Cubane Carboxylic Acids to Alkoxy Cubanes Using the Hofer-Moest Reaction under Flow Conditions.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Diego E Collin , Ana A Folgueiras-Amador , Derek Pletcher , Mark E Light , Richard C D Brown

A New Straightforward Method for Lipophilicity (logP) Measurement using 19F NMR Spectroscopy.

Journal of visualized experiments : JoVE

Avec: Zhong Wang , Benjamin F Jeffries , Hannah R Felstead , Neil J Wells , Elisabetta Chiarparin ,

Synthesis and Conformational Properties of 3,4-Difluoro-l-prolines.

The Journal of organic chemistry

Avec: Gert-Jan Hofman , Emile Ottoy , Mark E Light , Bruno Kieffer , Jose C Martins , Ilya Kuprov , Davy Sinnaeve ,

Synthesis of

Organic letters

Avec: Diego E Collin , Kristina Kovacic , Mark E Light ,

Relating Conformational Equilibria to Conformer-Specific Lipophilicities: New Opportunities in Drug Discovery.

Angewandte Chemie (International ed. in English)

Avec: Zhong Wang , Benjamin Jeffries , Jérôme Graton , Rodrigo J Carbajo , Davy Sinnaeve , Jean-Yves Le Questel , James S Scott , Elisabetta Chiarparin

The Synthesis and Glycoside Formation of Polyfluorinated Carbohydrates.

Chemical reviews

Avec: Kler Huonnic ,

Novel chemotype NLRP3 inhibitors that target the CRID3-binding pocket with high potency.

Life science alliance

Avec: Lieselotte Vande Walle , Madhukar Said , Oonagh Paerewijck , Arinna Bertoni , Marco Gattorno , Mohamed Lamkanfi

Photoinduced Formation of Cubyl Aryl Thioethers and Synthesis of Monocubyl Analogue of Dapsone.

Organic letters

Avec: Laly Donnier-Valentin , Seydou Kassamba , Julien Legros , Catherine Fressigné , Daniela Vuluga , Richard C D Brown , Michaël De Paolis

Harnessing glycofluoroforms for impedimetric biosensing.

Chemical science

Avec: Alice R Hewson , Henry O Lloyd-Laney , Tessa Keenan , Sarah-Jane Richards , Matthew I Gibson , Nathalie Signoret , Martin A Fascione , Alison Parkin

The Journal of organic chemistry

Avec: Sébastien Depienne , Clément Q Fontenelle , Mark E Light , Kristof Van Hecke ,

Réseau de co-auteurs

Jean-Baptiste Vendeville 9 collaborations

Tessa Keenan 6 collaborations

Mark E Light 6 collaborations

Martin A Fascione 6 collaborations

Zhong Wang 6 collaborations

Jean-Yves Le Questel 5 collaborations

Elisabetta Chiarparin 5 collaborations

Jérôme Graton 5 collaborations

David E Wheatley 5 collaborations

Jesús Jiménez-Barbero 4 collaborations

M Carmen Galan 4 collaborations

Julien Malassis 4 collaborations

Benjamin Jeffries 4 collaborations

James S Scott 4 collaborations

Clement Q Fontenelle 4 collaborations

Ilya Kuprov 4 collaborations

Davy Sinnaeve 4 collaborations

Pablo Valverde 3 collaborations

Harriet Chidwick 3 collaborations

Kler Huonnic 3 collaborations

Kun Huang 3 collaborations

Hannah R Felstead 3 collaborations

Robert I Troup 3 collaborations

Sarah-Jane Richards 3 collaborations

Claire E Council 3 collaborations

Matthew I Gibson 3 collaborations

Fabio Parmeggiani 3 collaborations

Ana Ardá 3 collaborations

Kristian Hollingsworth 2 collaborations

Helene Ledru 2 collaborations

Sabine Flitsch 2 collaborations

W Bruce Turnbull 2 collaborations

Mark Light 2 collaborations

Charlene Fallan 2 collaborations

Neil J Wells 2 collaborations

Simon J Charnock 2 collaborations

Sabine L Flitsch 2 collaborations

Andrea Marchesi 2 collaborations

Carl Young 2 collaborations

Niels-Christian Reichardt 2 collaborations

J Daniel Martínez 2 collaborations

Sandra Delgado 2 collaborations

Emile Ottoy 2 collaborations

Gert-Jan Hofman 2 collaborations

Bruno Kieffer 2 collaborations

Neil Wells 2 collaborations

Diego E Collin 2 collaborations

Richard C D Brown 2 collaborations

Ashley P Mattey 1 collaboration

Nicholas Turner 1 collaboration

Qui-Hien Nguyen 1 collaboration

Marie Boujon 1 collaboration

Quentin Gaignard-Gaillard 1 collaboration

Natasha E Hatton 1 collaboration

Jack Porter 1 collaboration

Mattia Ghirardello 1 collaboration

Alice J C Wahart 1 collaboration

Sanaz Ahmadipour 1 collaboration

Julia Walton 1 collaboration

Gavin J Miller 1 collaboration

Dmitry Shishmarev 1 collaboration

Philip W Kuchel 1 collaboration

Raphael El-Bekri Saudain 1 collaboration

Eleni Georgiou 1 collaboration

Johanna Fish 1 collaboration

Darshita Budhadev 1 collaboration

Claire S Webster 1 collaboration

Alexander N Baker 1 collaboration

Marc Walker 1 collaboration

Ramakrishna Kuppala 1 collaboration

Robert Szpera 1 collaboration

Edward L Briggs 1 collaboration

Emily E Kempa 1 collaboration

James L Galman 1 collaboration

James R Marshall 1 collaboration

Nicholas J Turner 1 collaboration

Perdita E Barran 1 collaboration

Philip T F Williamson 1 collaboration

Antonio Di Maio 1 collaboration

Hélène Ledru 1 collaboration

Wengang Chai 1 collaboration

Ryan McBerney 1 collaboration

Tomasz P Kamiński 1 collaboration

Matthew R Balmforth 1 collaboration

Alexandra Tamasanu 1 collaboration

James D Finnigan 1 collaboration

Stuart L Warriner 1 collaboration

Michael E Webb 1 collaboration

Ten Feizi 1 collaboration

Yan Liu 1 collaboration

Matthieu Sollogoub 1 collaboration

Luca Unione 1 collaboration

Stéphane P Vincent 1 collaboration

Cecilia Romanò 1 collaboration

Niels C Reichardt 1 collaboration

Stefan Oscarson 1 collaboration

F Javier Cañada 1 collaboration

Francisco Javier Cañada 1 collaboration

Lucas Quiquempoix 1 collaboration

Peter G Latchem 1 collaboration

Samuel Golten 1 collaboration

Allan Patinec 1 collaboration

Katy Akoumany 1 collaboration

Jézabel Rocher 1 collaboration

Denis Jacquemin 1 collaboration

Arnaud Tessier 1 collaboration

Jacques Lebreton 1 collaboration

Virginie Blot 1 collaboration

Muriel Pipelier 1 collaboration

Jean-Yves Douillard 1 collaboration

Jacques Le Pendu 1 collaboration

Didier Dubreuil 1 collaboration

Anaïs Goupille 1 collaboration

Abir Ben Bouzayene 1 collaboration

Eva Erdmann 1 collaboration

José C Martins 1 collaboration

Vladimir Torbeev 1 collaboration

Gabija Poškaitė 1 collaboration

Cassia Chiari 1 collaboration

Patrick R Batista 1 collaboration

Renan V Viesser 1 collaboration

Leonardo A Schenberg 1 collaboration

Lucas C Ducati 1 collaboration

Cláudio F Tormena 1 collaboration

William G Poole 1 collaboration

Florent Peron 1 collaboration

Stephen J Fox 1 collaboration

Chris-Kriton Skylaris 1 collaboration

Jonathan W Essex 1 collaboration

Wendy Offen 1 collaboration

Peter Both 1 collaboration

Alex Heyam 1 collaboration

Gideon J Davies 1 collaboration

Kelly J Kilpin 1 collaboration

Jessica S Gusthart 1 collaboration

Sarah A Allman 1 collaboration

Seung Seo Lee 1 collaboration

Ana A Folgueiras-Amador 1 collaboration

Derek Pletcher 1 collaboration

Benjamin F Jeffries 1 collaboration

Jose C Martins 1 collaboration

Kristina Kovacic 1 collaboration

Rodrigo J Carbajo 1 collaboration

Lieselotte Vande Walle 1 collaboration

Madhukar Said 1 collaboration

Oonagh Paerewijck 1 collaboration

Arinna Bertoni 1 collaboration

Marco Gattorno 1 collaboration

Mohamed Lamkanfi 1 collaboration

Laly Donnier-Valentin 1 collaboration

Seydou Kassamba 1 collaboration

Julien Legros 1 collaboration

Catherine Fressigné 1 collaboration

Daniela Vuluga 1 collaboration

Michaël De Paolis 1 collaboration

Alice R Hewson 1 collaboration

Henry O Lloyd-Laney 1 collaboration

Nathalie Signoret 1 collaboration

Alison Parkin 1 collaboration

Sébastien Depienne 1 collaboration

Clément Q Fontenelle 1 collaboration

Kristof Van Hecke 1 collaboration