Ayman E El-Sahar

Affiliations

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, Egypt.

Publications (20)

New insights into the effects of vinpocetine against neurobehavioral comorbidities in a rat model of temporal lobe epilepsy via the downregulation of the hippocampal PI3K/mTOR signalling pathway.

The Journal of pharmacy and pharmacology

Avec: Sarah S El-Sayed , Mohammed F El-Yamany , Hesham A Salem ,

Modulation of histone deacetylase, the ubiquitin proteasome system, and autophagy underlies the neuroprotective effects of venlafaxine in a rotenone-induced Parkinson's disease model in rats.

Chemico-biological interactions

Avec: Khalid A El-Saiy , Rabab H Sayed , Esraa A Kandil

Neuroprotective effects of vildagliptin on drug induced Alzheimer's disease in rats with metabolic syndrome: Role of hippocampal klotho and AKT signaling pathways.

European journal of pharmacology

Avec: Rasha R Yossef , Mohamed F Al-Yamany , Muhammed A Saad ,

Vildagliptin attenuates acetic acid-induced colitis in rats via targeting PI3K/Akt/NFκB, Nrf2 and CREB signaling pathways and the expression of lncRNA IFNG-AS1 and miR-146a.

International immunopharmacology

Avec: Marina R Fouad , Rania M Salama , Hala F Zaki ,

Lercanidipine boosts the efficacy of mesenchymal stem cell therapy in 3-NP-induced Huntington's disease model rats via modulation of the calcium/calcineurin/NFATc4 and Wnt/β-catenin signalling pathways.

Neurochemistry international

Avec: Eman M Elbaz , Hebatullah S Helmy , Muhammed A Saad , Rabab H Sayed

Addressing Peroxisome Proliferator-Activated Receptor-gamma in 3-Nitropropionic Acid-Induced Striatal Neurotoxicity in Rats.

Molecular neurobiology

Avec: Riham M Mansour , Nesrine S El Sayed , Maha A E Ahmed ,

Unleashing lactoferrin's antidepressant potential through the PI3K/Akt/mTOR pathway in chronic restraint stress rats.

Food & function

Avec: Hanan H Ahmed , Reham M Essam , Muhammed F El-Yamany , Kawkab A Ahmed ,

Mechanistic perspective of morin protection against ketoprofen-induced gastric mucosal injury: Targeting HMGB1/RAGE/NF-κB, DJ-1/Nrf2/HO-1 and PI3K/mTOR pathways.

Archives of biochemistry and biophysics

Avec: Hany H Arab , Muhammed A Saad , Muhammad Y Al-Shorbagy

Aberrations of miR-126-3p, miR-181a and sirtuin1 network mediate Di-(2-ethylhexyl) phthalate-induced testicular damage in rats: The protective role of hesperidin.

Toxicology

Avec: Hebatullah S Helmy , Mahmoud A Senousy , Rabab H Sayed , Muhammed A Saad , Eman M Elbaz

Dapagliflozin diminishes memory and cognition impairment in Streptozotocin induced diabetes through its effect on Wnt/β-Catenin and CREB pathway.

Brain research bulletin

Avec: Hala El-Safty , Ashraf Ismail , Rania M Abdelsalam , Muhammed A Saad

Vitamin D ameliorates diethylnitrosamine-induced liver preneoplasia: A pivotal role of CYP3A4/CYP2E1 via DPP-4 enzyme inhibition.

Toxicology and applied pharmacology

Avec: Hebatollah E Eitah , Hanan Naeim Attia , Ahmed A F Soliman , Amina A Gamal El Din , Khaled Mahmoud , Rabab H Sayed , Yousreya A Maklad ,

Repurposing ezetimibe as a neuroprotective agent in a rotenone-induced Parkinson's disease model in rats: Role of AMPK/SIRT-1/PGC-1α signaling and autophagy.

International immunopharmacology

Avec: Wessam H Elesawy , Rabab H Sayed , Ahmed M Ashour , Shuruq E Alsufyani , Hany H Arab , Esraa A Kandil

Empagliflozin Dampens Doxorubicin-Induced Chemobrain in Rats: The Possible Involvement of Oxidative Stress and PI3K/Akt/mTOR/NF-κB/TNF-α Signaling Pathways.

Molecular neurobiology

Avec: Rania M Abdelsalam , Hatem W Hamam , Noha M Eissa , Reham M Essam

Dapagliflozin improves behavioral dysfunction of Huntington's disease in rats via inhibiting apoptosis-related glycolysis.

Life sciences

Avec: Alyasaa A Rastanawi , Muhammed F El-Yamany , Muhammed A Saad

Venlafaxine Mitigates Depressive-Like Behavior in Ovariectomized Rats by Activating the EPO/EPOR/JAK2 Signaling Pathway and Increasing the Serum Estradiol Level.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Muhammed A Saad , Rabab H Sayed , Eman M Elbaz , Hebatullah S Helmy , Mahmoud A Senousy

Alogliptin Attenuates Lipopolysaccharide-Induced Neuroinflammation in Mice Through Modulation of TLR4/MYD88/NF-κB and miRNA-155/SOCS-1 Signaling Pathways.

The international journal of neuropsychopharmacology

Avec: Nesma A Shiha , Nesrine S El Sayed , Lamiaa A Ahmed

Inosine attenuates 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats via the activation of the A2AR/BDNF/TrKB/ERK/CREB signaling pathway.

Life sciences

Avec: Marwa El-Sayed El-Shamarka , Muhammed A Saad , Naglaa Assaf , Rabab H Sayed

Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats.

European journal of pharmacology

Avec: Reham A Mohammed , Rabab H Sayed , Mohamed A Khattab , Muhammed A Saad

Targeting HMGB1/PI3K/Akt and NF-κB/Nrf-2 signaling pathways by vildagliptin mitigates testosterone-induced benign prostate hyperplasia in rats.

Life sciences

Avec: Nadine Bekhit , Noha M Eissa , Rania M Abdelsalam , Reham M Essam

Lactoferrin averts neurological and behavioral impairments of thioacetamide-induced hepatic encephalopathy in rats via modulating HGMB1/TLR-4/MyD88/Nrf2 pathway.

Neuropharmacology

Avec: Reham M Essam , Mariam A Saadawy , Mahitab Gamal , Rania M Abdelsalam ,

Réseau de co-auteurs

Muhammed A Saad 9 collaborations

Rabab H Sayed 8 collaborations

Reham M Essam 4 collaborations

Rania M Abdelsalam 4 collaborations

Eman M Elbaz 3 collaborations

Hebatullah S Helmy 3 collaborations

Esraa A Kandil 2 collaborations

Nesrine S El Sayed 2 collaborations

Muhammed F El-Yamany 2 collaborations

Hany H Arab 2 collaborations

Mahmoud A Senousy 2 collaborations

Noha M Eissa 2 collaborations

Sarah S El-Sayed 1 collaboration

Mohammed F El-Yamany 1 collaboration

Hesham A Salem 1 collaboration

Khalid A El-Saiy 1 collaboration

Rasha R Yossef 1 collaboration

Mohamed F Al-Yamany 1 collaboration

Marina R Fouad 1 collaboration

Rania M Salama 1 collaboration

Hala F Zaki 1 collaboration

Riham M Mansour 1 collaboration

Maha A E Ahmed 1 collaboration

Hanan H Ahmed 1 collaboration

Kawkab A Ahmed 1 collaboration

Muhammad Y Al-Shorbagy 1 collaboration

Hala El-Safty 1 collaboration

Ashraf Ismail 1 collaboration

Hebatollah E Eitah 1 collaboration

Hanan Naeim Attia 1 collaboration

Ahmed A F Soliman 1 collaboration

Amina A Gamal El Din 1 collaboration

Khaled Mahmoud 1 collaboration

Yousreya A Maklad 1 collaboration

Wessam H Elesawy 1 collaboration

Ahmed M Ashour 1 collaboration

Shuruq E Alsufyani 1 collaboration

Hatem W Hamam 1 collaboration

Alyasaa A Rastanawi 1 collaboration

Nesma A Shiha 1 collaboration

Lamiaa A Ahmed 1 collaboration

Marwa El-Sayed El-Shamarka 1 collaboration

Naglaa Assaf 1 collaboration

Reham A Mohammed 1 collaboration

Mohamed A Khattab 1 collaboration

Nadine Bekhit 1 collaboration

Mariam A Saadawy 1 collaboration

Mahitab Gamal 1 collaboration