Arnaud Chevrollier

Affiliations

MitoLab Team (M.C., A.C., C.B., D.G., V.D.-D., S.L., V.P., P.R., D.B., P.A.-B., G.L.), UMR CNRS 6015-INSERM U1083, Institut MitoVasc, Angers University and Hospital; Genetics and immuno-cell therapy Team (M.C.), Mohammed First University, Oujda, Morocco; Departments of Biochemistry and Genetics (C.B., D.G., V.D.-D., E.C., V.P., P.R., D.B., P.A.-B.), University Hospital Angers; Department of Ophthalmology (A.M.), Centre Hospitalier Universitaire Saint-Pierre, Brussels, Belgium; Neuroophthalmology Department (C.V.), Rothschild Ophthalmologic Foundation, Paris; Exploration of Visual Function and Neuro-Ophthalmology Department (V.S., S.D.-D., I.D.B.), Lille University Hospital, Rue Emilie Laine, Lille Cedex; CHU Bordeaux (C.G.), Service de Génétique Médicale, Centre de Référence « Neurogénétique » and Université de Bordeaux, INSERM U 1211, Laboratoire Maladies Rares, Génétique et Métabolisme (MRGM) Bordeaux; School of Optometry and Vision Sciences (M.V.), Cardiff University and Cardiff Eye Unit, University Hospital of Wales; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology (N.J., P.Y.-W.-M.), London; Department of Clinical Neurosciences (P.Y.-W.-M.), Cambridge Centre for Brain Repair and MRC Mitochondrial Biology Unit, University of Cambridge; Cambridge Eye Unit (P.Y.-W.-M.), Addenbrooke's Hospital, Cambridge University Hospitals, UK; IRCCS Istituto Delle Scienze Neurologiche di Bologna (F.T., L.C., C.L.M., V.C.), Bellaria Hospital; Unit of Neurology (C.L.M., V.C.), Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Italy; Centre de Compétence Maladies Rares (X.Z.), Clinique Pluridisciplinaire Jules Verne, Nantes; and National Centre in Rare Diseases (I.M.), Genetics of Sensory Diseases, University Hospital, Montpellier, France.

Publications (21)

Mutations in the m-AAA proteases AFG3L2 and SPG7 are causing isolated dominant optic atrophy.

Neurology. Genetics

Avec: Majida Charif , Naïg Gueguen , Céline Bris , David Goudenège , Valérie Desquiret-Dumas , Stéphanie Leruez , Estelle Colin , Audrey Meunier , Catherine Vignal , Vasily Smirnov , Sabine Defoort-Dhellemmes , Isabelle Drumare Bouvet , Cyril Goizet , Marcela Votruba , Neringa Jurkute , Patrick Yu-Wai-Man , Francesca Tagliavini , Leonardo Caporali , Chiara La Morgia , Valerio Carelli , Vincent Procaccio , Xavier Zanlonghi , Isabelle Meunier , Pascal Reynier , Dominique Bonneau , Patrizia Amati-Bonneau , Guy Lenaers

Dominant

Brain communications

Avec: Majida Charif , Naïg Gueguen , Marc Ferré , Zouhair Elkarhat , Salim Khiati , Morgane LeMao , Valerie Desquiret-Dumas , David Goudenège , Céline Bris , Selma Kane , Jennifer Alban , Stéphanie Chupin , Céline Wetterwald , Leonardo Caporali , Francesca Tagliavini , Chiara LaMorgia , Michele Carbonelli , Neringa Jurkute , Abdelhamid Barakat , Philippe Gohier , Christophe Verny , Magalie Barth , Vincent Procaccio , Dominique Bonneau , Xavier Zanlonghi , Isabelle Meunier , Nicole Weisschuh , Simone Schimpf-Linzenbold , Felix Tonagel , Ulrich Kellner , Patrick Yu-Wai-Man , Valerio Carelli , Bernd Wissinger , Patrizia Amati-Bonneau , Pascal Reynier , Auteur inconnu , Guy Lenaers

Homozygous MFN2 variants causing severe antenatal encephalopathy with clumped mitochondria.

Brain : a journal of neurology

Avec: Adeline Alice Bonnard , Lyse Ruaud , Naïg Gueguen , Laurence Perrin , Valérie Desquiret-Dumas , Fabien Guimiot , Pierre-Hadrien Becker , Jonathan Levy , Pascal Reynier , Pauline Gaignard

Protective role of the mitochondrial fusion protein OPA1 in hypertension.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Pauline Robert , Phuc Minh Chau Nguyen , Alexis Richard , Céline Grenier , Mathilde Munier , Linda Grimaud , Coralyne Proux , Tristan Champin , Eric Lelièvre , Emmanuelle Sarzi , Emilie Vessières , Samir Henni , Delphine Prunier , Pascal Reynier , Guys Lenaers , Céline Fassot , Daniel Henrion , Laurent Loufrani

Next-Generation Sequencing Identifies Novel

Genes

Avec: Majida Charif , Naïg Gueguen , Selma Kane , Céline Bris , David Goudenège , Valerie Desquiret-Dumas , Isabelle Meunier , Fanny Mochel , Luc Jeanjean , Fanny Varenne , Vincent Procaccio , Pascal Reynier , Dominique Bonneau , Patrizia Amati-Bonneau , Guy Lenaers

Ketogenic diet enhances the anti-cancer effects of PD-L1 blockade in renal cell carcinoma.

Frontiers in endocrinology

Avec: Jeremy Richard , Céline Beauvillain , Maxime Benoit , Magalie Barth , Cécile Aubert , Cyrielle Rolley , Sarah Bellal , Jennifer Bourreau , Matthieu Ferragu , Souhil Lebdai , Daniel Henrion , Vincent Procaccio , Pierre Bigot

Transactive response DNA-binding protein 43 is enriched at the centrosome in human cells.

Brain : a journal of neurology

Avec: Alexia Bodin , Logan Greibill , Julien Gouju , Franck Letournel , Silvia Pozzi , Jean-Pierre Julien , Laurence Renaud , Delphine Bohl , Stéphanie Millecamps , Christophe Verny , Julien Cassereau , Guy Lenaers , Anne-Marie Tassin , Philippe Codron

STochastic Optical Reconstruction Microscopy (STORM) reveals the nanoscale organization of pathological aggregates in human brain.

Neuropathology and applied neurobiology

Avec: P Codron , F Letournel , S Marty , L Renaud , A Bodin , M Duchesne , C Verny , G Lenaers , C Duyckaerts , J-P Julien , J Cassereau , A Chevrollier

The Long Non-Coding RNA SAMMSON Is a Regulator of Chemosensitivity and Metabolic Orientation in MCF-7 Doxorubicin-Resistant Breast Cancer Cells.

Biology

Avec: Charlotte Orre , Xavier Dieu , Jordan Guillon , Naïg Gueguen , Seyedeh Tayebeh Ahmadpour , Jean-François Dumas , Salim Khiati , Pascal Reynier , Guy Lenaers , Olivier Coqueret , Delphine Mirebeau-Prunier , Valérie Desquiret-Dumas

Warburg-like effect is a hallmark of complex I assembly defects.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Valerie Desquiret-Dumas , Geraldine Leman , Celine Wetterwald , Stephanie Chupin , Anaïs Lebert , Salim Khiati , Morgane Le Mao , Guillaume Geffroy , Mariame Selma Kane , David Goudenege , Cedric Gadras , Lydie Tessier , Magalie Barth , Stephanie Leruez , Patrizia Amati-Bonneau , Daniel Henrion , Dominique Bonneau , Vincent Procaccio , Pascal Reynier , Guy Lenaers , Naig Gueguen

Lipidomics Reveals Triacylglycerol Accumulation Due to Impaired Fatty Acid Flux in Opa1-Disrupted Fibroblasts.

Journal of proteome research

Avec: Cinzia Bocca , Mariame Selma Kane , Charlotte Veyrat-Durebex , Judith Kouassi Nzoughet , Juan Manuel Chao de la Barca , Stephanie Chupin , Jennifer Alban , Vincent Procaccio , Dominique Bonneau , Gilles Simard , Guy Lenaers , Pascal Reynier ,

Stochastic Optical Reconstruction Microscopy Imaging of Multiple System Atrophy Inclusions Suggests Stepwise α-Synuclein Aggregation.

Movement disorders : official journal of the Movement Disorder Society

Avec: Benoît Vovard , Alexia Bodin , Julien Gouju , Adrien de Guilhem de Lataillade , Pascal Derkinderen , Frédérique Etcharry-Bouyx , Valérie Chauviré , Virginie Guillet-Pichon , Christophe Verny , Franck Letournel , Guy Lenaers , Philippe Codron

MICU2 up-regulation enhances tumor aggressiveness and metabolic reprogramming during colorectal cancer development.

PLoS biology

Avec: Alison Robert , David Crottès , Jérôme Bourgeais , Naig Gueguen , Jean-François Dumas , Stéphane Servais , Isabelle Domingo , Stéphanie Chadet , Julien Sobilo , Olivier Hérault , Thierry Lecomte , Christophe Vandier , William Raoul , Maxime Guéguinou

Oxidative stress contributes differentially to the pathophysiology of Charcot-Marie-Tooth disease type 2K.

Experimental neurology

Avec: Julien Cassereau , Philippe Codron , Cyril Goizet , Naïg Gueguen , Christophe Verny , Pascal Reynier , Dominique Bonneau , Guy Lenaers , Vincent Procaccio

LPS-enriched small extracellular vesicles from metabolic syndrome patients trigger endothelial dysfunction by activation of TLR4.

Metabolism: clinical and experimental

Avec: Sakina Ali , Marine Malloci , Zainab Safiedeen , Raffaella Soleti , Luisa Vergori , Xavier Vidal-Gómez , Charlène Besnard , Séverine Dubois , Soazig Le Lay , Jérôme Boursier , Frédéric Gagnadoux , Gilles Simard , Ramaroson Andriantsitohaina , M Carmen Martinez , Auteur inconnu

Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance.

Mitochondrion

Avec: Jade Aurrière , David Goudenege , Simone A Baechler , Shar-Yin N Huang , Naig Gueguen , Valerie Desquiret-Dumas , Floris Chabrun , Rodolphe Perrot , Majida Charif , Olivier R Baris , Yves Pommier , Guy Lenaers , Salim Khiati

Case report: Thirty-year progression of an EMPF1 encephalopathy due to defective mitochondrial and peroxisomal fission caused by a novel

Frontiers in neurology

Avec: Charlène Lhuissier , Bart E Wagner , Amy Vincent , Gaëtan Garraux , Olivier Hougrand , Rudy Van Coster , Valerie Benoit , Deniz Karadurmus , Guy Lenaers , Naïg Gueguen , Isabelle Maystadt

Glutamate-Induced Deregulation of Krebs Cycle in Mitochondrial Encephalopathy Lactic Acidosis Syndrome Stroke-Like Episodes (MELAS) Syndrome Is Alleviated by Ketone Body Exposure.

Biomedicines

Avec: Sophie Belal , David Goudenège , Cinzia Bocca , Florent Dumont , Juan Manuel Chao De La Barca , Valérie Desquiret-Dumas , Naïg Gueguen , Guillaume Geffroy , Rayane Benyahia , Selma Kane , Salim Khiati , Céline Bris , Tamas Aranyi , Daniel Stockholm , Aurore Inisan , Aurélie Renaud , Magalie Barth , Gilles Simard , Pascal Reynier , Franck Letournel , Guy Lenaers , Dominique Bonneau , Vincent Procaccio

Super-resolution microscopies, technological breakthrough to decipher mitochondrial structure and dynamic.

Seminars in cell & developmental biology

Avec: Pauline Teixeira , Rémi Galland ,

Food perception induces fast fragmentation of hepatic mitochondria.

Trends in endocrinology and metabolism: TEM

Avec: Jérome Boursier , Valérie Desquiret-Dumas

Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission.

iScience

Avec: Charlène Lhuissier , Valérie Desquiret-Dumas , Anaïs Girona , Jennifer Alban , Justine Faure , Julien Cassereau , Philippe Codron , Guy Lenaers , Olivier R Baris , Naïg Gueguen ,

Réseau de co-auteurs

Guy Lenaers 13 collaborations

Pascal Reynier 10 collaborations

Naïg Gueguen 9 collaborations

Vincent Procaccio 8 collaborations

Dominique Bonneau 7 collaborations

Valérie Desquiret-Dumas 6 collaborations

Salim Khiati 5 collaborations

Majida Charif 4 collaborations

Céline Bris 4 collaborations

David Goudenège 4 collaborations

Patrizia Amati-Bonneau 4 collaborations

Valerie Desquiret-Dumas 4 collaborations

Christophe Verny 4 collaborations

Magalie Barth 4 collaborations

Philippe Codron 4 collaborations

Isabelle Meunier 3 collaborations

Selma Kane 3 collaborations

Jennifer Alban 3 collaborations

Daniel Henrion 3 collaborations

Franck Letournel 3 collaborations

Julien Cassereau 3 collaborations

Naig Gueguen 3 collaborations

Gilles Simard 3 collaborations

Cyril Goizet 2 collaborations

Neringa Jurkute 2 collaborations

Patrick Yu-Wai-Man 2 collaborations

Francesca Tagliavini 2 collaborations

Leonardo Caporali 2 collaborations

Valerio Carelli 2 collaborations

Xavier Zanlonghi 2 collaborations

None None 2 collaborations

Alexia Bodin 2 collaborations

Julien Gouju 2 collaborations

Jean-François Dumas 2 collaborations

Stephanie Chupin 2 collaborations

Guillaume Geffroy 2 collaborations

Mariame Selma Kane 2 collaborations

David Goudenege 2 collaborations

Cinzia Bocca 2 collaborations

Olivier R Baris 2 collaborations

Charlène Lhuissier 2 collaborations

Stéphanie Leruez 1 collaboration

Estelle Colin 1 collaboration

Audrey Meunier 1 collaboration

Catherine Vignal 1 collaboration

Vasily Smirnov 1 collaboration

Sabine Defoort-Dhellemmes 1 collaboration

Isabelle Drumare Bouvet 1 collaboration

Marcela Votruba 1 collaboration

Chiara La Morgia 1 collaboration

Marc Ferré 1 collaboration

Zouhair Elkarhat 1 collaboration

Morgane LeMao 1 collaboration

Stéphanie Chupin 1 collaboration

Céline Wetterwald 1 collaboration

Chiara LaMorgia 1 collaboration

Michele Carbonelli 1 collaboration

Abdelhamid Barakat 1 collaboration

Philippe Gohier 1 collaboration

Nicole Weisschuh 1 collaboration

Simone Schimpf-Linzenbold 1 collaboration

Felix Tonagel 1 collaboration

Ulrich Kellner 1 collaboration

Bernd Wissinger 1 collaboration

Adeline Alice Bonnard 1 collaboration

Lyse Ruaud 1 collaboration

Laurence Perrin 1 collaboration

Fabien Guimiot 1 collaboration

Pierre-Hadrien Becker 1 collaboration

Jonathan Levy 1 collaboration

Pauline Gaignard 1 collaboration

Pauline Robert 1 collaboration

Phuc Minh Chau Nguyen 1 collaboration

Alexis Richard 1 collaboration

Céline Grenier 1 collaboration

Mathilde Munier 1 collaboration

Linda Grimaud 1 collaboration

Coralyne Proux 1 collaboration

Tristan Champin 1 collaboration

Eric Lelièvre 1 collaboration

Emmanuelle Sarzi 1 collaboration

Emilie Vessières 1 collaboration

Samir Henni 1 collaboration

Delphine Prunier 1 collaboration

Guys Lenaers 1 collaboration

Céline Fassot 1 collaboration

Laurent Loufrani 1 collaboration

Fanny Mochel 1 collaboration

Luc Jeanjean 1 collaboration

Fanny Varenne 1 collaboration

Jeremy Richard 1 collaboration

Céline Beauvillain 1 collaboration

Maxime Benoit 1 collaboration

Cécile Aubert 1 collaboration

Cyrielle Rolley 1 collaboration

Sarah Bellal 1 collaboration

Jennifer Bourreau 1 collaboration

Matthieu Ferragu 1 collaboration

Souhil Lebdai 1 collaboration

Pierre Bigot 1 collaboration

Logan Greibill 1 collaboration

Silvia Pozzi 1 collaboration

Jean-Pierre Julien 1 collaboration

Laurence Renaud 1 collaboration

Delphine Bohl 1 collaboration

Stéphanie Millecamps 1 collaboration

Anne-Marie Tassin 1 collaboration

P Codron 1 collaboration

F Letournel 1 collaboration

S Marty 1 collaboration

L Renaud 1 collaboration

A Bodin 1 collaboration

M Duchesne 1 collaboration

C Verny 1 collaboration

G Lenaers 1 collaboration

C Duyckaerts 1 collaboration

J-P Julien 1 collaboration

J Cassereau 1 collaboration

A Chevrollier 1 collaboration

Charlotte Orre 1 collaboration

Xavier Dieu 1 collaboration

Jordan Guillon 1 collaboration

Seyedeh Tayebeh Ahmadpour 1 collaboration

Olivier Coqueret 1 collaboration

Delphine Mirebeau-Prunier 1 collaboration

Geraldine Leman 1 collaboration

Celine Wetterwald 1 collaboration

Anaïs Lebert 1 collaboration

Morgane Le Mao 1 collaboration

Cedric Gadras 1 collaboration

Lydie Tessier 1 collaboration

Stephanie Leruez 1 collaboration

Charlotte Veyrat-Durebex 1 collaboration

Judith Kouassi Nzoughet 1 collaboration

Juan Manuel Chao de la Barca 1 collaboration

Benoît Vovard 1 collaboration

Adrien de Guilhem de Lataillade 1 collaboration

Pascal Derkinderen 1 collaboration

Frédérique Etcharry-Bouyx 1 collaboration

Valérie Chauviré 1 collaboration

Virginie Guillet-Pichon 1 collaboration

Alison Robert 1 collaboration

David Crottès 1 collaboration

Jérôme Bourgeais 1 collaboration

Stéphane Servais 1 collaboration

Isabelle Domingo 1 collaboration

Stéphanie Chadet 1 collaboration

Julien Sobilo 1 collaboration

Olivier Hérault 1 collaboration

Thierry Lecomte 1 collaboration

Christophe Vandier 1 collaboration

William Raoul 1 collaboration

Maxime Guéguinou 1 collaboration

Sakina Ali 1 collaboration

Marine Malloci 1 collaboration

Zainab Safiedeen 1 collaboration

Raffaella Soleti 1 collaboration

Luisa Vergori 1 collaboration

Xavier Vidal-Gómez 1 collaboration

Charlène Besnard 1 collaboration

Séverine Dubois 1 collaboration

Soazig Le Lay 1 collaboration

Jérôme Boursier 1 collaboration

Frédéric Gagnadoux 1 collaboration

Ramaroson Andriantsitohaina 1 collaboration

M Carmen Martinez 1 collaboration

Jade Aurrière 1 collaboration

Simone A Baechler 1 collaboration

Shar-Yin N Huang 1 collaboration

Floris Chabrun 1 collaboration

Rodolphe Perrot 1 collaboration

Yves Pommier 1 collaboration

Bart E Wagner 1 collaboration

Amy Vincent 1 collaboration

Gaëtan Garraux 1 collaboration

Olivier Hougrand 1 collaboration

Rudy Van Coster 1 collaboration

Valerie Benoit 1 collaboration

Deniz Karadurmus 1 collaboration

Isabelle Maystadt 1 collaboration

Sophie Belal 1 collaboration

Florent Dumont 1 collaboration

Juan Manuel Chao De La Barca 1 collaboration

Rayane Benyahia 1 collaboration

Tamas Aranyi 1 collaboration

Daniel Stockholm 1 collaboration

Aurore Inisan 1 collaboration

Aurélie Renaud 1 collaboration

Pauline Teixeira 1 collaboration

Rémi Galland 1 collaboration

Jérome Boursier 1 collaboration

Anaïs Girona 1 collaboration

Justine Faure 1 collaboration