Arash Grakoui

Affiliations

Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes Research Primate Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Publications (31)

Neutralization and receptor use of infectious culture-derived rat hepacivirus as a model for HCV.

Hepatology (Baltimore, Md.)

Avec: Raphael Wolfisberg , Caroline E Thorselius , Eduardo Salinas , Elizabeth Elrod , Sheetal Trivedi , Louise Nielsen , Ulrik Fahnøe , Amit Kapoor , Charles M Rice , Jens Bukh , Kenn Holmbeck , Troels K H Scheel

CD4

Science advances

Avec: Meenakshi Kar , Katherine E E Johnson , Abigail Vanderheiden , Elizabeth J Elrod , Katharine Floyd , Elizabeth Geerling , E Taylor Stone , Eduardo Salinas , Stephanie Banakis , Wei Wang , Shruti Sathish , Swathi Shrihari , Meredith E Davis-Gardner , Jacob Kohlmeier , Amelia Pinto , Robyn Klein , Elodie Ghedin , Mehul S Suthar

Activation-Induced Marker Assay to Identify and Isolate HCV-Specific T Cells for Single-Cell RNA-Seq Analysis.

Viruses

Avec: Mohamed Eisa , Nicol Flores , Omar Khedr , Elsa Gomez-Escobar , Nathalie Bédard , Nourtan F Abdeltawab , Julie Bruneau , Naglaa H Shoukry

Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures.

Journal of virology

Avec: Abigail Vanderheiden , Philipp Ralfs , Tatiana Chirkova , Amit A Upadhyay , Matthew G Zimmerman , Shamika Bedoya , Hadj Aoued , Gregory M Tharp , Kathryn L Pellegrini , Candela Manfredi , Eric Sorscher , Bernardo Mainou , Jenna L Lobby , Jacob E Kohlmeier , Anice C Lowen , Pei-Yong Shi , Vineet D Menachery , Larry J Anderson , Steven E Bosinger , Mehul S Suthar

Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability.

Hepatology communications

Avec: Daniel M Chopyk , Johnasha D Stuart , Matthew G Zimmerman , Jing Wen , Sanjeev Gumber , Mehul S Suthar , Manoj Thapa , Mark J Czaja ,

Immune system control of hepatitis C virus infection.

Current opinion in virology

Avec: Johnasha D Stuart , Eduardo Salinas ,

Plasmacytoid dendritic cells produce type I interferon and reduce viral replication in airway epithelial cells after SARS-CoV-2 infection.

bioRxiv : the preprint server for biology

Avec: Luisa Cervantes-Barragan , Abigail Vanderheiden , Charlotte J Royer , Meredith E Davis-Gardner , Philipp Ralfs , Tatiana Chirkova , Larry J Anderson , Mehul S Suthar

CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection.

bioRxiv : the preprint server for biology

Avec: Abigail Vanderheiden , Jeronay Thomas , Allison L Soung , Meredith E Davis-Gardner , Katharine Floyd , Fengzhi Jin , David A Cowan , Kathryn Pellegrini , Adrian Creanga , Amarendra Pegu , Alexandrine Derrien-Colemyn , Pei-Yong Shi , Robyn S Klein , Steven E Bosinger , Jacob E Kohlmeier , Vineet D Menachery , Mehul S Suthar

Regions of hepatitis C virus E2 required for membrane association.

Nature communications

Avec: Ashish Kumar , Tiana C Rohe , Elizabeth J Elrod , Abdul G Khan , Altaira D Dearborn , Ryan Kissinger , Joseph Marcotrigiano

CD4+ T cell restoration and control of hepatitis C virus replication after childbirth.

The Journal of clinical investigation

Avec: Samantha L Coss , Almudena Torres-Cornejo , Mona R Prasad , Melissa Moore-Clingenpeel , Georg M Lauer , Christopher M Walker , Jonathan R Honegger

Contribution of the Intestinal Microbiome and Gut Barrier to Hepatic Disorders.

Gastroenterology

Avec: Daniel M Chopyk ,

mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant.

Cell reports. Medicine

Avec: Venkata-Viswanadh Edara , Kelly E Manning , Madison Ellis , Lilin Lai , Kathryn M Moore , Stephanie L Foster , Katharine Floyd , Meredith E Davis-Gardner , Grace Mantus , Lindsay E Nyhoff , Sarah Bechnak , Ghina Alaaeddine , Amal Naji , Hady Samaha , Matthew Lee , Laurel Bristow , Matthew Gagne , Jesmine Roberts-Torres , Amy R Henry , Sucheta Godbole , Marybeth Saxton , Anne Piantadosi , Jesse J Waggoner , Daniel C Douek , Nadine Rouphael , Jens Wrammert , Mehul S Suthar

Translocation of gut commensal bacteria to the brain.

bioRxiv : the preprint server for biology

Avec: Manoj Thapa , Anuradha Kumari , Chui-Yoke Chin , Jacob E Choby , Fengzhi Jin , Bikash Bogati , Daniel M Chopyk , Nitya Koduri , Andrew Pahnke , Elizabeth J Elrod , Eileen M Burd , David S Weiss ,

BiliQML: A supervised machine-learning model to quantify biliary forms from digitized whole-slide liver histopathological images.

American journal of physiology. Gastrointestinal and liver physiology

Avec: Dominick J Hellen , Meredith E Fay , David H Lee , Caroline Klindt-Morgan , Ashley Bennett , Kimberly J Pachura , Stacey S Huppert , Paul A Dawson , Wilbur A Lam , Saul J Karpen

Hyperfunctional T cell responses unchecked by regulatory T cells are unable to resolve hepaciviral infection without humoral contribution.

Journal of hepatology

Avec: Fengzhi Jin , John Gridley , Anuradha Kumari , Alireza Saeidi , Brantley Holland , Elizabeth Elrod , Piyush Dravid , Sheetal Trivedi , Amit Kapoor , Manoj Thapa ,

Mechanotransduction in T Cell Development, Differentiation and Function.

Cells

Avec: Muaz Rushdi , Kaitao Li , Zhou Yuan , Stefano Travaglino , Cheng Zhu

Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion.

The Journal of clinical investigation

Avec: Eduardo Salinas , Maude Boisvert , Amit A Upadhyay , Nathalie Bédard , Sydney A Nelson , Julie Bruneau , Cynthia A Derdeyn , Joseph Marcotrigiano , Matthew J Evans , Steven E Bosinger , Naglaa H Shoukry ,

Soluble ORF2 protein enhances HEV replication and induces long-lasting antibody response and protective immunity in vivo.

Hepatology (Baltimore, Md.)

Avec: Philipp Ralfs , Brantley Holland , Eduardo Salinas , Bill Bremer , Minghang Wang , Jingting Zhu , Charuta Ambardekar , Heather Blasczyk , Christopher M Walker , Zongdi Feng ,

Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.

PLoS pathogens

Avec: Piyush Dravid , Satyapramod Murthy , Zayed Attia , Cole Cassady , Rahul Chandra , Sheetal Trivedi , Ashish Vyas , John Gridley , Brantley Holland , Anuradha Kumari , John M Cullen , Christopher M Walker , Himanshu Sharma , Amit Kapoor

Western diet dampens T regulatory cell function to fuel hepatic inflammation in nonalcoholic fatty liver disease.

bioRxiv : the preprint server for biology

Avec: Sudrishti Chaudhary , Ravi Rai , Pabitra B Pal , Dana Tedesco , Aatur D Singhi , Satdarshan P Monga , Smita S Iyer , Reben Raeman

Concerted synergy between viral-specific IgG and CD8+ T cells is critical for clearance of an HCV-related rodent hepacivirus.

Hepatology (Baltimore, Md.)

Avec: John Gridley , Brantley Holland , Eduardo Salinas , Sheetal Trivedi , Piyush Dravid , Elizabeth Elrod , Fengzhi Jin , Anuradha Kumari , Mariana N Batista , Manoj Thapa , Charles M Rice , Joseph Marcotrigiano , Amit Kapoor ,

Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Manoj Thapa , Dana Tedesco , Sanjeev Gumber , Elizabeth J Elrod , Jin-Hwan Han , William H Kitchens , Joseph F Magliocca , Andrew B Adams ,

Structural insights into hepatitis C virus receptor binding and entry.

Nature

Avec: Ashish Kumar , Reafa A Hossain , Samantha A Yost , Wei Bu , Yuanyuan Wang , Altaira D Dearborn , Jeffrey I Cohen , Joseph Marcotrigiano

CCR2 Signaling Restricts SARS-CoV-2 Infection.

mBio

Avec: Abigail Vanderheiden , Jeronay Thomas , Allison L Soung , Meredith E Davis-Gardner , Katharine Floyd , Fengzhi Jin , David A Cowan , Kathryn Pellegrini , Pei-Yong Shi , Robyn S Klein , Steven E Bosinger , Jacob E Kohlmeier , Vineet D Menachery , Mehul S Suthar

Resolution of hepatitis E virus infection in CD8+ T cell-depleted rhesus macaques.

Journal of hepatology

Avec: William Bremer , Heather Blasczyk , Xin Yin , Eduardo Salinas , Zongdi Feng , Christopher Walker

mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 Omicron variant.

bioRxiv : the preprint server for biology

Avec: Venkata-Viswanadh Edara , Kelly E Manning , Madison Ellis , Lilin Lai , Kathryn M Moore , Stephanie L Foster , Katharine Floyd , Meredith E Davis-Gardner , Grace Mantus , Lindsay E Nyhoff , Sarah Bechnak , Ghina Alaaeddine , Amal Naji , Hady Samaha , Matthew Lee , Laurel Bristow , Laila Hussaini , Caroline Rose Ciric , Phuong-Vi Nguyen , Matthew Gagne , Jesmine Roberts-Torres , Amy R Henry , Sucheta Godbole , Marybeth Sexton , Anne Piantadosi , Jesse J Waggoner , Daniel C Douek , Evan J Anderson , Nadine Rouphael , Jens Wrammert , Mehul S Suthar

Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects.

PLoS pathogens

Avec: Sabrina Mazouz , Eduardo Salinas , Nathalie Bédard , Ali Filali , Omar Khedr , Leo Swadling , Mohamed S Abdel-Hakeem , Asiyah Siddique , Eleanor Barnes , Julie Bruneau , Naglaa H Shoukry

Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C.

Nature communications

Avec: Akira Nishio , Sharika Hasan , Heiyoung Park , Nana Park , Jordan H Salas , Eduardo Salinas , Lela Kardava , Paul Juneau , Nicole Frumento , Guido Massaccesi , Susan Moir , Justin R Bailey , Marc G Ghany , Barbara Rehermann

CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment.

bioRxiv : the preprint server for biology

Eosinophils protect against SARS-CoV-2 following a vaccine breakthrough infection.

bioRxiv : the preprint server for biology

Avec: Kathryn M Moore , Stephanie L Foster , Meenakshi Kar , Katharine A Floyd , Elizabeth J Elrod , M Elliott Williams , Jacob Vander Velden , Madison Ellis , Ansa Malik , Bushra Wali , Stacey Lapp , Amanda Metz , Steven E Bosinger , Vineet D Menachery , Robert A Seder , Rama Rao Amara , Jacob E Kohlmeier , Mehul S Suthar

Coordinated expansion of memory T follicular helper and B cells mediates spontaneous clearance of HCV reinfection.

Frontiers in immunology

Avec: Mohamed Eisa , Elsa Gomez-Escobar , Nathalie Bédard , Nourtan F Abdeltawab , Nicol Flores , Sabrina Mazouz , Alizée Fieffé-Bédard , Patrick Sakayan , John Gridley , Mohamed S Abdel-Hakeem , Julie Bruneau , Naglaa H Shoukry

Réseau de co-auteurs

Eduardo Salinas 10 collaborations

Mehul S Suthar 10 collaborations

Meredith E Davis-Gardner 7 collaborations

Abigail Vanderheiden 6 collaborations

Elizabeth J Elrod 6 collaborations

Katharine Floyd 6 collaborations

Steven E Bosinger 5 collaborations

Manoj Thapa 5 collaborations

Fengzhi Jin 5 collaborations

Sheetal Trivedi 4 collaborations

Amit Kapoor 4 collaborations

Nathalie Bédard 4 collaborations

Julie Bruneau 4 collaborations

Naglaa H Shoukry 4 collaborations

Jacob E Kohlmeier 4 collaborations

Vineet D Menachery 4 collaborations

Joseph Marcotrigiano 4 collaborations

Anuradha Kumari 4 collaborations

John Gridley 4 collaborations

Brantley Holland 4 collaborations

Elizabeth Elrod 3 collaborations

Meenakshi Kar 3 collaborations

Philipp Ralfs 3 collaborations

Pei-Yong Shi 3 collaborations

Daniel M Chopyk 3 collaborations

Christopher M Walker 3 collaborations

Madison Ellis 3 collaborations

Kathryn M Moore 3 collaborations

Stephanie L Foster 3 collaborations

Piyush Dravid 3 collaborations

Charles M Rice 2 collaborations

Katherine E E Johnson 2 collaborations

Elizabeth Geerling 2 collaborations

E Taylor Stone 2 collaborations

Stephanie Banakis 2 collaborations

Wei Wang 2 collaborations

Shruti Sathish 2 collaborations

Swathi Shrihari 2 collaborations

Jacob Kohlmeier 2 collaborations

Amelia Pinto 2 collaborations

Robyn Klein 2 collaborations

Elodie Ghedin 2 collaborations

Mohamed Eisa 2 collaborations

Nicol Flores 2 collaborations

Omar Khedr 2 collaborations

Elsa Gomez-Escobar 2 collaborations

Nourtan F Abdeltawab 2 collaborations

Tatiana Chirkova 2 collaborations

Amit A Upadhyay 2 collaborations

Matthew G Zimmerman 2 collaborations

Larry J Anderson 2 collaborations

Johnasha D Stuart 2 collaborations

Sanjeev Gumber 2 collaborations

Jeronay Thomas 2 collaborations

Allison L Soung 2 collaborations

David A Cowan 2 collaborations

Kathryn Pellegrini 2 collaborations

Robyn S Klein 2 collaborations

Ashish Kumar 2 collaborations

Altaira D Dearborn 2 collaborations

Venkata-Viswanadh Edara 2 collaborations

Kelly E Manning 2 collaborations

Lilin Lai 2 collaborations

Grace Mantus 2 collaborations

Lindsay E Nyhoff 2 collaborations

Sarah Bechnak 2 collaborations

Ghina Alaaeddine 2 collaborations

Amal Naji 2 collaborations

Hady Samaha 2 collaborations

Matthew Lee 2 collaborations

Laurel Bristow 2 collaborations

Matthew Gagne 2 collaborations

Jesmine Roberts-Torres 2 collaborations

Amy R Henry 2 collaborations

Sucheta Godbole 2 collaborations

Anne Piantadosi 2 collaborations

Jesse J Waggoner 2 collaborations

Daniel C Douek 2 collaborations

Nadine Rouphael 2 collaborations

Jens Wrammert 2 collaborations

Heather Blasczyk 2 collaborations

Zongdi Feng 2 collaborations

Dana Tedesco 2 collaborations

Sabrina Mazouz 2 collaborations

Mohamed S Abdel-Hakeem 2 collaborations

Raphael Wolfisberg 1 collaboration

Caroline E Thorselius 1 collaboration

Louise Nielsen 1 collaboration

Ulrik Fahnøe 1 collaboration

Jens Bukh 1 collaboration

Kenn Holmbeck 1 collaboration

Troels K H Scheel 1 collaboration

Shamika Bedoya 1 collaboration

Hadj Aoued 1 collaboration

Gregory M Tharp 1 collaboration

Kathryn L Pellegrini 1 collaboration

Candela Manfredi 1 collaboration

Eric Sorscher 1 collaboration

Bernardo Mainou 1 collaboration

Jenna L Lobby 1 collaboration

Anice C Lowen 1 collaboration

Jing Wen 1 collaboration

Mark J Czaja 1 collaboration

Luisa Cervantes-Barragan 1 collaboration

Charlotte J Royer 1 collaboration

Adrian Creanga 1 collaboration

Amarendra Pegu 1 collaboration

Alexandrine Derrien-Colemyn 1 collaboration

Tiana C Rohe 1 collaboration

Abdul G Khan 1 collaboration

Ryan Kissinger 1 collaboration

Samantha L Coss 1 collaboration

Almudena Torres-Cornejo 1 collaboration

Mona R Prasad 1 collaboration

Melissa Moore-Clingenpeel 1 collaboration

Georg M Lauer 1 collaboration

Jonathan R Honegger 1 collaboration

Marybeth Saxton 1 collaboration

Chui-Yoke Chin 1 collaboration

Jacob E Choby 1 collaboration

Bikash Bogati 1 collaboration

Nitya Koduri 1 collaboration

Andrew Pahnke 1 collaboration

Eileen M Burd 1 collaboration

David S Weiss 1 collaboration

Dominick J Hellen 1 collaboration

Meredith E Fay 1 collaboration

David H Lee 1 collaboration

Caroline Klindt-Morgan 1 collaboration

Ashley Bennett 1 collaboration

Kimberly J Pachura 1 collaboration

Stacey S Huppert 1 collaboration

Paul A Dawson 1 collaboration

Wilbur A Lam 1 collaboration

Saul J Karpen 1 collaboration

Alireza Saeidi 1 collaboration

Muaz Rushdi 1 collaboration

Kaitao Li 1 collaboration

Zhou Yuan 1 collaboration

Stefano Travaglino 1 collaboration

Cheng Zhu 1 collaboration

Maude Boisvert 1 collaboration

Sydney A Nelson 1 collaboration

Cynthia A Derdeyn 1 collaboration

Matthew J Evans 1 collaboration

Bill Bremer 1 collaboration

Minghang Wang 1 collaboration

Jingting Zhu 1 collaboration

Charuta Ambardekar 1 collaboration

Satyapramod Murthy 1 collaboration

Zayed Attia 1 collaboration

Cole Cassady 1 collaboration

Rahul Chandra 1 collaboration

Ashish Vyas 1 collaboration

John M Cullen 1 collaboration

Himanshu Sharma 1 collaboration

Sudrishti Chaudhary 1 collaboration

Ravi Rai 1 collaboration

Pabitra B Pal 1 collaboration

Aatur D Singhi 1 collaboration

Satdarshan P Monga 1 collaboration

Smita S Iyer 1 collaboration

Reben Raeman 1 collaboration

Mariana N Batista 1 collaboration

Jin-Hwan Han 1 collaboration

William H Kitchens 1 collaboration

Joseph F Magliocca 1 collaboration

Andrew B Adams 1 collaboration

Reafa A Hossain 1 collaboration

Samantha A Yost 1 collaboration

Wei Bu 1 collaboration

Yuanyuan Wang 1 collaboration

Jeffrey I Cohen 1 collaboration

William Bremer 1 collaboration

Xin Yin 1 collaboration

Christopher Walker 1 collaboration

Laila Hussaini 1 collaboration

Caroline Rose Ciric 1 collaboration

Phuong-Vi Nguyen 1 collaboration

Marybeth Sexton 1 collaboration

Evan J Anderson 1 collaboration

Ali Filali 1 collaboration

Leo Swadling 1 collaboration

Asiyah Siddique 1 collaboration

Eleanor Barnes 1 collaboration

Akira Nishio 1 collaboration

Sharika Hasan 1 collaboration

Heiyoung Park 1 collaboration

Nana Park 1 collaboration

Jordan H Salas 1 collaboration

Lela Kardava 1 collaboration

Paul Juneau 1 collaboration

Nicole Frumento 1 collaboration

Guido Massaccesi 1 collaboration

Susan Moir 1 collaboration

Justin R Bailey 1 collaboration

Marc G Ghany 1 collaboration

Barbara Rehermann 1 collaboration

Katharine A Floyd 1 collaboration

M Elliott Williams 1 collaboration

Jacob Vander Velden 1 collaboration

Ansa Malik 1 collaboration

Bushra Wali 1 collaboration

Stacey Lapp 1 collaboration

Amanda Metz 1 collaboration

Robert A Seder 1 collaboration

Rama Rao Amara 1 collaboration

Alizée Fieffé-Bédard 1 collaboration

Patrick Sakayan 1 collaboration