Anna-Liisa Levonen

Affiliations

A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.

Publications (23)

NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli.

Cardiovascular research

Avec: Suvi Linna-Kuosmanen , Vanesa Tomas Bosch , Pierre R Moreau , Maria Bouvy-Liivrand , Henri Niskanen , Emilia Kansanen , Annukka Kivelä , Juha Hartikainen , Mikko Hippeläinen , Hannu Kokki , Pasi Tavi , Minna U Kaikkonen

Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma.

Oncogene

Avec: Petri Pölönen , Ashik Jawahar Deen , Hanna M Leinonen , Henna-Kaisa Jyrkkänen , Suvi Kuosmanen , Mimmi Mononen , Ashish Jain , Tomi Tuomainen , Sanna Pasonen-Seppänen , Jaana M Hartikainen , Arto Mannermaa , Matti Nykter , Pasi Tavi , Terje Johansen , Merja Heinäniemi ,

Electrophilic metabolites targeting the KEAP1/NRF2 partnership.

Current opinion in chemical biology

Avec: Albena T Dinkova-Kostova , Henriikka Hakomäki ,

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function.

Frontiers in physiology

Avec: Suvi Jauhiainen , Johanna P Laakkonen , Kirsi Ketola , Pyry I Toivanen , Tiina Nieminen , Takeshi Ninchoji , Minna U Kaikkonen , Seppo Ylä-Herttuala

NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes.

Glia

Avec: Minna Oksanen , Ida Hyötyläinen , Kalevi Trontti , Taisia Rolova , Sara Wojciechowski , Marja Koskuvi , Matti Viitanen , Iiris Hovatta , Laurent Roybon , Šárka Lehtonen , Katja M Kanninen , Riikka H Hämäläinen , Jari Koistinaho

LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models.

Circulation research

Avec: Lídia Cedó , Jari Metso , David Santos , Annabel García-León , Núria Plana , Sonia Sabate-Soler , Noemí Rotllan , Andrea Rivas-Urbina , Karen A Méndez-Lara , Mireia Tondo , Josefa Girona , Josep Julve , Victor Pallarès , Aleyda Benitez-Amaro , Vicenta Llorente-Cortes , Antonio Pérez , Diego Gómez-Coronado , Anna-Kaisa Ruotsalainen , José Luis Sanchez-Quesada , Luís Masana , Petri T Kovanen , Matti Jauhiainen , Miriam Lee-Rueckert , Francisco Blanco-Vaca , Joan Carles Escolà-Gil

Global MicroRNA Profiling of Vascular Endothelial Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Eloi Schmauch , Suvi Linna-Kuosmanen

Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.

Redox biology

Avec: Ashik Jawahar Deen , Simone Adinolfi , Jouni Härkönen , Tommi Patinen , Xiaonan Liu , Tuomo Laitinen , Piia Takabe , Kirsi Kainulainen , Sanna Pasonen-Seppänen , Lisa M Gawriyski , Uma Thanigai Arasu , Ilakya Selvarajan , Petri Mäkinen , Hanna Laitinen , Emilia Kansanen , Minna U Kaikkonen , Antti Poso , Markku Varjosalo ,

The EDCMET Project: Metabolic Effects of Endocrine Disruptors.

International journal of molecular sciences

Avec: Jenni Küblbeck , Taina Vuorio , Jonna Niskanen , Vittorio Fortino , Albert Braeuning , Khaled Abass , Arja Rautio , Jukka Hakkola , Paavo Honkakoski ,

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.

International journal of molecular sciences

Avec: Anssi Lipponen , Teemu Natunen , Mika Hujo , Robert Ciszek , Elina Hämäläinen , Jussi Tohka , Mikko Hiltunen , Jussi Paananen , David Poulsen , Emilia Kansanen , Xavier Ekolle Ndode-Ekane , Asla Pitkänen

Regulation of stress signaling pathways by protein lipoxidation.

Redox biology

Avec: Tommi Patinen , Simone Adinolfi , Carlos Cruz Cortés , Jouni Härkönen , Ashik Jawahar Deen ,

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice.

Cardiovascular research

Avec: Anna-Kaisa Ruotsalainen , Jari P Lappalainen , Emmi Heiskanen , Mari Merentie , Virve Sihvola , Juha Näpänkangas , Line Lottonen-Raikaslehto , Emilia Kansanen , Simone Adinolfi , Kai Kaarniranta , Seppo Ylä-Herttuala , Matti Jauhiainen , Eija Pirinen ,

A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase.

Oncogenesis

Avec: Miika Mehine , Terhi Ahvenainen , Sara Khamaiseh , Jouni Härkönen , Siiri Reinikka , Tuomas Heikkinen , Anna Äyräväinen , Päivi Pakarinen , Päivi Härkki , Annukka Pasanen , Ralf Bützow , Pia Vahteristo

Metabolic effects of nuclear receptor activation in vivo after 28-day oral exposure to three endocrine-disrupting chemicals.

Archives of toxicology

Avec: Brecht Attema , Outi Kummu , Sini Pitkänen , Jonna Weisell , Taina Vuorio , Erika Pennanen , Maria Vorimo , Jaana Rysä , Sander Kersten , Jukka Hakkola

Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice.

Nucleic acids research

Avec: Juho Mononen , Mari Taipale , Marjo Malinen , Bharadwaja Velidendla , Einari Niskanen , Anna-Kaisa Ruotsalainen , Sami Heikkinen

HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.

Cellular and molecular life sciences : CMLS

Avec: Uma Thanigai Arasu , Ashik Jawahar Deen , Sanna Pasonen-Seppänen , Sami Heikkinen , Maciej Lalowski , Riikka Kärnä , Kai Härkönen , Petri Mäkinen , Elisa Lázaro-Ibáñez , Pia R-M Siljander , Sanna Oikari , Kirsi Rilla

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.

Nature reviews. Drug discovery

Avec: Antonio Cuadrado , Ana I Rojo , Geoffrey Wells , John D Hayes , Sharon P Cousin , William L Rumsey , Otis C Attucks , Stephen Franklin , Thomas W Kensler , Albena T Dinkova-Kostova

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.

Redox biology

Avec: Szabolcs Felszeghy , Johanna Viiri , Jussi J Paterno , Juha M T Hyttinen , Ali Koskela , Mei Chen , Henri Leinonen , Heikki Tanila , Niko Kivinen , Arto Koistinen , Elisa Toropainen , Marialaura Amadio , Adrian Smedowski , Mika Reinisalo , Mateusz Winiarczyk , Jerzy Mackiewicz , Maija Mutikainen , Anna-Kaisa Ruotsalainen , Mikko Kettunen , Kimmo Jokivarsi , Debasish Sinha , Kati Kinnunen , Goran Petrovski , Janusz Blasiak , Geir Bjørkøy , Ari Koskelainen , Heli Skottman , Arto Urtti , Antero Salminen , Ram Kannan , Deborah A Ferrington , Heping Xu , Pasi Tavi , Anu Kauppinen , Kai Kaarniranta

Characterizing valve dynamics in mice by high-resolution cine-MRI.

NMR in biomedicine

Avec: Jonna Weisell , Anna-Kaisa Ruotsalainen , Hanne Laakso , Elias Ylä-Herttuala , Juha Näpänkangas , Timo Liimatainen , Jaana Rysä

Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.

American journal of human genetics

Avec: Ilakya Selvarajan , Anu Toropainen , Kristina M Garske , Maykel López Rodríguez , Arthur Ko , Zong Miao , Dorota Kaminska , Kadri Õunap , Tiit Örd , Aarthi Ravindran , Oscar H Liu , Pierre R Moreau , Ashik Jawahar Deen , Ville Männistö , Calvin Pan , Aldons J Lusis , Sami Heikkinen , Casey E Romanoski , Jussi Pihlajamäki , Päivi Pajukanta , Minna U Kaikkonen

PI3Kβ inhibition enhances ALK-inhibitor sensitivity in ALK-rearranged lung cancer.

Molecular oncology

Avec: Sarang S Talwelkar , Mikko I Mäyränpää , Julia Schüler , Nora Linnavirta , Annabrita Hemmes , Simone Adinolfi , Matti Kankainen , Wolfgang Sommergruber , Jari Räsänen , Aija Knuuttila , Emmy W Verschuren , Krister Wennerberg

A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies.

Redox biology

Avec: Jouni Härkönen , Petri Pölönen , Ashik Jawahar Deen , Ilakya Selvarajan , Hanna-Riikka Teppo , Elitsa Y Dimova , Thomas Kietzmann , Maarit Ahtiainen , Juha P Väyrynen , Sara A Väyrynen , Hanna Elomaa , Niko Tynkkynen , Tiia Eklund , Teijo Kuopio , Eva-Maria Talvitie , Pekka Taimen , Markku Kallajoki , Minna U Kaikkonen , Merja Heinäniemi ,

The KEAP1-NRF2 pathway: Targets for therapy and role in cancer.

Redox biology

Avec: Simone Adinolfi , Tommi Patinen , Ashik Jawahar Deen , Sini Pitkänen , Jouni Härkönen , Emilia Kansanen , Jenni Küblbeck ,

Réseau de co-auteurs

Ashik Jawahar Deen 7 collaborations

Emilia Kansanen 5 collaborations

Minna U Kaikkonen 5 collaborations

Anna-Kaisa Ruotsalainen 5 collaborations

Simone Adinolfi 5 collaborations

Jouni Härkönen 5 collaborations

Pasi Tavi 3 collaborations

Sanna Pasonen-Seppänen 3 collaborations

Tommi Patinen 3 collaborations

Ilakya Selvarajan 3 collaborations

Sami Heikkinen 3 collaborations

Suvi Linna-Kuosmanen 2 collaborations

Pierre R Moreau 2 collaborations

Petri Pölönen 2 collaborations

Merja Heinäniemi 2 collaborations

Albena T Dinkova-Kostova 2 collaborations

Seppo Ylä-Herttuala 2 collaborations

Matti Jauhiainen 2 collaborations

Uma Thanigai Arasu 2 collaborations

Petri Mäkinen 2 collaborations

Jenni Küblbeck 2 collaborations

Taina Vuorio 2 collaborations

Jukka Hakkola 2 collaborations

Juha Näpänkangas 2 collaborations

Kai Kaarniranta 2 collaborations

Sini Pitkänen 2 collaborations

Jonna Weisell 2 collaborations

Jaana Rysä 2 collaborations

Vanesa Tomas Bosch 1 collaboration

Maria Bouvy-Liivrand 1 collaboration

Henri Niskanen 1 collaboration

Annukka Kivelä 1 collaboration

Juha Hartikainen 1 collaboration

Mikko Hippeläinen 1 collaboration

Hannu Kokki 1 collaboration

Hanna M Leinonen 1 collaboration

Henna-Kaisa Jyrkkänen 1 collaboration

Suvi Kuosmanen 1 collaboration

Mimmi Mononen 1 collaboration

Ashish Jain 1 collaboration

Tomi Tuomainen 1 collaboration

Jaana M Hartikainen 1 collaboration

Arto Mannermaa 1 collaboration

Matti Nykter 1 collaboration

Terje Johansen 1 collaboration

Henriikka Hakomäki 1 collaboration

Suvi Jauhiainen 1 collaboration

Johanna P Laakkonen 1 collaboration

Kirsi Ketola 1 collaboration

Pyry I Toivanen 1 collaboration

Tiina Nieminen 1 collaboration

Takeshi Ninchoji 1 collaboration

Minna Oksanen 1 collaboration

Ida Hyötyläinen 1 collaboration

Kalevi Trontti 1 collaboration

Taisia Rolova 1 collaboration

Sara Wojciechowski 1 collaboration

Marja Koskuvi 1 collaboration

Matti Viitanen 1 collaboration

Iiris Hovatta 1 collaboration

Laurent Roybon 1 collaboration

Šárka Lehtonen 1 collaboration

Katja M Kanninen 1 collaboration

Riikka H Hämäläinen 1 collaboration

Jari Koistinaho 1 collaboration

Lídia Cedó 1 collaboration

Jari Metso 1 collaboration

David Santos 1 collaboration

Annabel García-León 1 collaboration

Núria Plana 1 collaboration

Sonia Sabate-Soler 1 collaboration

Noemí Rotllan 1 collaboration

Andrea Rivas-Urbina 1 collaboration

Karen A Méndez-Lara 1 collaboration

Mireia Tondo 1 collaboration

Josefa Girona 1 collaboration

Josep Julve 1 collaboration

Victor Pallarès 1 collaboration

Aleyda Benitez-Amaro 1 collaboration

Vicenta Llorente-Cortes 1 collaboration

Antonio Pérez 1 collaboration

Diego Gómez-Coronado 1 collaboration

José Luis Sanchez-Quesada 1 collaboration

Luís Masana 1 collaboration

Petri T Kovanen 1 collaboration

Miriam Lee-Rueckert 1 collaboration

Francisco Blanco-Vaca 1 collaboration

Joan Carles Escolà-Gil 1 collaboration

Eloi Schmauch 1 collaboration

Xiaonan Liu 1 collaboration

Tuomo Laitinen 1 collaboration

Piia Takabe 1 collaboration

Kirsi Kainulainen 1 collaboration

Lisa M Gawriyski 1 collaboration

Hanna Laitinen 1 collaboration

Antti Poso 1 collaboration

Markku Varjosalo 1 collaboration

Jonna Niskanen 1 collaboration

Vittorio Fortino 1 collaboration

Albert Braeuning 1 collaboration

Khaled Abass 1 collaboration

Arja Rautio 1 collaboration

Paavo Honkakoski 1 collaboration

Anssi Lipponen 1 collaboration

Teemu Natunen 1 collaboration

Mika Hujo 1 collaboration

Robert Ciszek 1 collaboration

Elina Hämäläinen 1 collaboration

Jussi Tohka 1 collaboration

Mikko Hiltunen 1 collaboration

Jussi Paananen 1 collaboration

David Poulsen 1 collaboration

Xavier Ekolle Ndode-Ekane 1 collaboration

Asla Pitkänen 1 collaboration

Carlos Cruz Cortés 1 collaboration

Jari P Lappalainen 1 collaboration

Emmi Heiskanen 1 collaboration

Mari Merentie 1 collaboration

Virve Sihvola 1 collaboration

Line Lottonen-Raikaslehto 1 collaboration

Eija Pirinen 1 collaboration

Miika Mehine 1 collaboration

Terhi Ahvenainen 1 collaboration

Sara Khamaiseh 1 collaboration

Siiri Reinikka 1 collaboration

Tuomas Heikkinen 1 collaboration

Anna Äyräväinen 1 collaboration

Päivi Pakarinen 1 collaboration

Päivi Härkki 1 collaboration

Annukka Pasanen 1 collaboration

Ralf Bützow 1 collaboration

Pia Vahteristo 1 collaboration

Brecht Attema 1 collaboration

Outi Kummu 1 collaboration

Erika Pennanen 1 collaboration

Maria Vorimo 1 collaboration

Sander Kersten 1 collaboration

Juho Mononen 1 collaboration

Mari Taipale 1 collaboration

Marjo Malinen 1 collaboration

Bharadwaja Velidendla 1 collaboration

Einari Niskanen 1 collaboration

Maciej Lalowski 1 collaboration

Riikka Kärnä 1 collaboration

Kai Härkönen 1 collaboration

Elisa Lázaro-Ibáñez 1 collaboration

Pia R-M Siljander 1 collaboration

Sanna Oikari 1 collaboration

Kirsi Rilla 1 collaboration

Antonio Cuadrado 1 collaboration

Ana I Rojo 1 collaboration

Geoffrey Wells 1 collaboration

John D Hayes 1 collaboration

Sharon P Cousin 1 collaboration

William L Rumsey 1 collaboration

Otis C Attucks 1 collaboration

Stephen Franklin 1 collaboration

Thomas W Kensler 1 collaboration

Szabolcs Felszeghy 1 collaboration

Johanna Viiri 1 collaboration

Jussi J Paterno 1 collaboration

Juha M T Hyttinen 1 collaboration

Ali Koskela 1 collaboration

Mei Chen 1 collaboration

Henri Leinonen 1 collaboration

Heikki Tanila 1 collaboration

Niko Kivinen 1 collaboration

Arto Koistinen 1 collaboration

Elisa Toropainen 1 collaboration

Marialaura Amadio 1 collaboration

Adrian Smedowski 1 collaboration

Mika Reinisalo 1 collaboration

Mateusz Winiarczyk 1 collaboration

Jerzy Mackiewicz 1 collaboration

Maija Mutikainen 1 collaboration

Mikko Kettunen 1 collaboration

Kimmo Jokivarsi 1 collaboration

Debasish Sinha 1 collaboration

Kati Kinnunen 1 collaboration

Goran Petrovski 1 collaboration

Janusz Blasiak 1 collaboration

Geir Bjørkøy 1 collaboration

Ari Koskelainen 1 collaboration

Heli Skottman 1 collaboration

Arto Urtti 1 collaboration

Antero Salminen 1 collaboration

Ram Kannan 1 collaboration

Deborah A Ferrington 1 collaboration

Heping Xu 1 collaboration

Anu Kauppinen 1 collaboration

Hanne Laakso 1 collaboration

Elias Ylä-Herttuala 1 collaboration

Timo Liimatainen 1 collaboration

Anu Toropainen 1 collaboration

Kristina M Garske 1 collaboration

Maykel López Rodríguez 1 collaboration

Arthur Ko 1 collaboration

Zong Miao 1 collaboration

Dorota Kaminska 1 collaboration

Kadri Õunap 1 collaboration

Tiit Örd 1 collaboration

Aarthi Ravindran 1 collaboration

Oscar H Liu 1 collaboration

Ville Männistö 1 collaboration

Calvin Pan 1 collaboration

Aldons J Lusis 1 collaboration

Casey E Romanoski 1 collaboration

Jussi Pihlajamäki 1 collaboration

Päivi Pajukanta 1 collaboration

Sarang S Talwelkar 1 collaboration

Mikko I Mäyränpää 1 collaboration

Julia Schüler 1 collaboration

Nora Linnavirta 1 collaboration

Annabrita Hemmes 1 collaboration

Matti Kankainen 1 collaboration

Wolfgang Sommergruber 1 collaboration

Jari Räsänen 1 collaboration

Aija Knuuttila 1 collaboration

Emmy W Verschuren 1 collaboration

Krister Wennerberg 1 collaboration

Hanna-Riikka Teppo 1 collaboration

Elitsa Y Dimova 1 collaboration

Thomas Kietzmann 1 collaboration

Maarit Ahtiainen 1 collaboration

Juha P Väyrynen 1 collaboration

Sara A Väyrynen 1 collaboration

Hanna Elomaa 1 collaboration

Niko Tynkkynen 1 collaboration

Tiia Eklund 1 collaboration

Teijo Kuopio 1 collaboration

Eva-Maria Talvitie 1 collaboration

Pekka Taimen 1 collaboration

Markku Kallajoki 1 collaboration