Anil G Cashikar

Affiliations

Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA.

Publications (11)

Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation.

Acta neuropathologica

Avec: Fabia Filipello , Shih-Feng You , Farzaneh S Mirfakhar , Sidhartha Mahali , Bryan Bollman , Mariana Acquarone , Olena Korvatska , Jacob A Marsh , Anirudh Sivaraman , Rita Martinez , Claudia Cantoni , Luca De Feo , Laura Ghezzi , Miguel A Minaya , Arun Renganathan , Jun-Ichi Satoh , Wandy Beatty , Abhirami K Iyer , Marina Cella , Wendy H Raskind , Laura Piccio , Celeste M Karch

Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.

The Journal of experimental medicine

Avec: Danira Toral-Rios , Justin M Long , Jason D Ulrich , Jinsheng Yu , Michael R Strickland , Xianlin Han , David M Holtzman , Steven M Paul

Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol.

Journal of lipid research

Avec: Danira Toral-Rios , David Timm , Johnathan Romero , Michael Strickland , Justin M Long , Xianlin Han , David M Holtzman , Steven M Paul

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.

Journal of neuroinflammation

Avec: Man Ying Wong , Michael Lewis , James J Doherty , Yang Shi , Anna Amelianchik , Svitlana Tymchuk , Patrick M Sullivan , Mingxing Qian , Douglas F Covey , Gregory A Petsko , David M Holtzman , Steven M Paul , Wenjie Luo

A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Yukitoshi Izumi , Kathiresan Krishnan , Steven M Paul , Douglas F Covey , Steven J Mennerick , Charles F Zorumski

Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins.

Neuron

Avec: Michael R Strickland , Michael J Rau , Brock Summers , Katherine Basore , John Wulf , Hong Jiang , Yun Chen , Jason D Ulrich , Gwendalyn J Randolph , Rui Zhang , James A J Fitzpatrick , David M Holtzman

A cell-based assay for CD63-containing extracellular vesicles.

PloS one

Avec: Phyllis I Hanson

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.

Neuron

Avec: Alexandra Litvinchuk , Jung H Suh , Jing L Guo , Karin Lin , Sonnet S Davis , Nga Bien-Ly , Eric Tycksen , G Travis Tabor , Javier Remolina Serrano , Melissa Manis , Xin Bao , Choonghee Lee , Megan Bosch , Enmanuel J Perez , Carla M Yuede , Jason D Ulrich , Gilbert Di Paolo , David M Holtzman

MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state.

medRxiv : the preprint server for health sciences

Avec: Shih-Feng You , Logan Brase , Fabia Filipello , Abhirami K Iyer , Jorge Del-Aguila , June He , Ricardo D'Oliveira Albanus , John Budde , Joanne Norton , Jen Gentsch , Nina M Dräger , Sydney M Sattler , Martin Kampmann , Laura Piccio , John C Morris , Richard J Perrin , Eric McDade , Auteur inconnu , Steven M Paul , Bruno A Benitez , Oscar Harari , Celeste M Karch

Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning.

PloS one

Avec: Yukitoshi Izumi , Kazuko A O'Dell , Steven M Paul , Douglas F Covey , Steven J Mennerick , Charles F Zorumski

25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation.

Journal of neuroinflammation

Avec: Johnathan Romero , Danira Toral-Rios , Jinsheng Yu , Steven M Paul ,

Réseau de co-auteurs

Steven M Paul 7 collaborations

David M Holtzman 5 collaborations

Danira Toral-Rios 3 collaborations

Jason D Ulrich 3 collaborations

Douglas F Covey 3 collaborations

Fabia Filipello 2 collaborations

Shih-Feng You 2 collaborations

Abhirami K Iyer 2 collaborations

Laura Piccio 2 collaborations

Celeste M Karch 2 collaborations

Justin M Long 2 collaborations

Jinsheng Yu 2 collaborations

Michael R Strickland 2 collaborations

Xianlin Han 2 collaborations

Johnathan Romero 2 collaborations

Yukitoshi Izumi 2 collaborations

Steven J Mennerick 2 collaborations

Charles F Zorumski 2 collaborations

Farzaneh S Mirfakhar 1 collaboration

Sidhartha Mahali 1 collaboration

Bryan Bollman 1 collaboration

Mariana Acquarone 1 collaboration

Olena Korvatska 1 collaboration

Jacob A Marsh 1 collaboration

Anirudh Sivaraman 1 collaboration

Rita Martinez 1 collaboration

Claudia Cantoni 1 collaboration

Luca De Feo 1 collaboration

Laura Ghezzi 1 collaboration

Miguel A Minaya 1 collaboration

Arun Renganathan 1 collaboration

Jun-Ichi Satoh 1 collaboration

Wandy Beatty 1 collaboration

Marina Cella 1 collaboration

Wendy H Raskind 1 collaboration

David Timm 1 collaboration

Michael Strickland 1 collaboration

Man Ying Wong 1 collaboration

Michael Lewis 1 collaboration

James J Doherty 1 collaboration

Yang Shi 1 collaboration

Anna Amelianchik 1 collaboration

Svitlana Tymchuk 1 collaboration

Patrick M Sullivan 1 collaboration

Mingxing Qian 1 collaboration

Gregory A Petsko 1 collaboration

Wenjie Luo 1 collaboration

Kathiresan Krishnan 1 collaboration

Michael J Rau 1 collaboration

Brock Summers 1 collaboration

Katherine Basore 1 collaboration

John Wulf 1 collaboration

Hong Jiang 1 collaboration

Yun Chen 1 collaboration

Gwendalyn J Randolph 1 collaboration

Rui Zhang 1 collaboration

James A J Fitzpatrick 1 collaboration

Phyllis I Hanson 1 collaboration

Alexandra Litvinchuk 1 collaboration

Jung H Suh 1 collaboration

Jing L Guo 1 collaboration

Karin Lin 1 collaboration

Sonnet S Davis 1 collaboration

Nga Bien-Ly 1 collaboration

Eric Tycksen 1 collaboration

G Travis Tabor 1 collaboration

Javier Remolina Serrano 1 collaboration

Melissa Manis 1 collaboration

Xin Bao 1 collaboration

Choonghee Lee 1 collaboration

Megan Bosch 1 collaboration

Enmanuel J Perez 1 collaboration

Carla M Yuede 1 collaboration

Gilbert Di Paolo 1 collaboration

Logan Brase 1 collaboration

Jorge Del-Aguila 1 collaboration

June He 1 collaboration

Ricardo D'Oliveira Albanus 1 collaboration

John Budde 1 collaboration

Joanne Norton 1 collaboration

Jen Gentsch 1 collaboration

Nina M Dräger 1 collaboration

Sydney M Sattler 1 collaboration

Martin Kampmann 1 collaboration

John C Morris 1 collaboration

Richard J Perrin 1 collaboration

Eric McDade 1 collaboration

None None 1 collaboration

Bruno A Benitez 1 collaboration

Oscar Harari 1 collaboration

Kazuko A O'Dell 1 collaboration