Angela Maria Casaril

Affiliations

Technologic Development Center, Biotechnology Unit, Neurobiotechnology Research Group, Federal University of Pelotas, Pelotas, RS, Brazil.

Publications (27)

Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice.

Behavioural brain research

Avec: Micaela Domingues , Paloma Taborda Birmann , Suely Ribeiro Bampi , Darling de Andrade Lourenço , Beatriz M Vieira , Luiz H Dapper , Eder J Lenardão , Mariana Sonego , Tiago Collares , Fabiana K Seixas , César Augusto Brüning , Lucielli Savegnago

The selenocompound 1-methyl-3-(phenylselanyl)-1H-indole attenuates depression-like behavior, oxidative stress, and neuroinflammation in streptozotocin-treated mice.

Brain research bulletin

Avec: Suely Ribeiro Bampi , Mariana G Fronza , Micaela Domingues , Beatriz Vieira , Karine Rech Begnini , Fabiana K Seixas , Tiago Veiras Collares , Eder João Lenardão , Lucielli Savegnago

The antioxidant and immunomodulatory compound 3-[(4-chlorophenyl)selanyl]-1-methyl-1H-indole attenuates depression-like behavior and cognitive impairment developed in a mouse model of breast tumor.

Brain, behavior, and immunity

Avec: Micaela Domingues , Suely Ribeiro Bampi , Darling de Andrade Lourenço , Thiago Ângelo Smaniotto , Natália Segatto , Beatriz Vieira , Fabiana K Seixas , Tiago Collares , Eder João Lenardão , Lucielli Savegnago

Selanylimidazopyridine abolishes inflammation- and stress-induced depressive-like behaviors by modulating the oxido-nitrosative system.

European journal of pharmacology

Avec: Micaela Domingues , Thiago Ângelo Smaniotto , Paloma Taborda Birmann , Darling de Andrade Lourenço , Suely Ribeiro Bampi , Beatriz Vieira , Eder João Lenardão , Lucielli Savegnago

Neuroprotective Effect of 3-[(4-Chlorophenyl)selanyl]-1-methyl-1H-indole on Hydrogen Peroxide-Induced Oxidative Stress in SH-SY5Y Cells.

Neurochemical research

Avec: Natália Segatto , Lucas Simões , Júlia Paschoal , Micaela Domingues , Beatriz Vieira , Fernanda S S Sousa , Eder João Lenardão , Fabiana K Seixas , Tiago Collares , Lucielli Savegnago

Toxicological evaluation of 3-(4-Chlorophenylselanyl)-1-methyl-1H-indole through the bovine oocyte in vitro maturation model.

Toxicology in vitro : an international journal published in association with BIBRA

Avec: Júlia Damé Fonseca Paschoal , Isadora André Lopes , Morgana Alves Borges , Ana Laura Feijó , Lucas Damé Simões , Natália Vieira Segatto , Vinicius Farias Campos , Fabiana Seixas , Lucielli Savegnago , Eder João Lenardão , Tiago Collares

Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system.

Journal of psychiatric research

Avec: Micaela Domingues , Darling de Andrade Lourenço , Paloma Taborda Birmann , Nathalia Padilha , Beatriz Vieira , Karine Begnini , Fabiana Kommling Seixas , Tiago Collares , Eder João Lenardão , Lucielli Savegnago

Lipopolysaccharide does not alter behavioral response to successive negative contrast in mice.

Psychopharmacology

Avec: Angela M Casaril , Elisabeth G Vichaya , M Raafay Rishi , Bianca G Ford , Robert Dantzer

Komagataella pastoris KM71H modulates neuroimmune and oxidative stress parameters in animal models of depression: A proposal for a new probiotic with antidepressant-like effect.

Pharmacological research

Avec: Paloma T Birmann , Angela M Casaril , Ana Paula Pesarico , Pamela S Caballero , Thiago Â Smaniotto , Rafael R Rodrigues , Ângela N Moreira , Fabricio R Conceição , Fernanda S S Sousa , Tiago Collares , Fabiana K Seixas , Raqueli T França , Carine D Corcini , Lucielli Savegnago

In vitro and in silico trichomonacidal activity of 2,8-bis(trifluoromethyl) quinoline analogs against Trichomonas vaginalis.

Parasitology research

Avec: Mirna Samara Dié Alves , Ângela Sena-Lopes , Raquel Nascimento das Neves , Micaela Domingues , Paloma Taborda Birmann , Emerson Teixeira da Silva , Marcus Vinicius Nora de Souza , Lucielli Savegnago , Sibele Borsuk

Intranasal administration of interleukin-4 ameliorates depression-like behavior and biochemical alterations in mouse submitted to the chronic unpredictable mild stress: modulation of neuroinflammation and oxidative stress.

Psychopharmacology

Avec: Thiago Ângelo Smaniotto , Darling de Andrade Lourenço , Fernanda S Sousa , Fabiana K Seixas , Tiago Collares , Rafael Woloski , Luciano da Silva Pinto , Diego Alves , Lucielli Savegnago

A pyrazole-containing selenium compound modulates neuroendocrine, oxidative stress, and behavioral responses to acute restraint stress in mice.

Behavioural brain research

Avec: Paloma T Birmann , Micaela Domingues , Angela M Casaril , Thiago Â Smaniotto , Daniela Hartwig , Raquel G Jacob , Lucielli Savegnago

A novel pyrazole-containing selenium compound modulates the oxidative and nitrergic pathways to reverse the depression-pain syndrome in mice.

Brain research

Avec: Paloma T Birmann , Angela M Casaril , Daniela Hartwig , Raquel G Jacob , Fabiana K Seixas , Tiago Collares , Lucielli Savegnago

Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses.

Parasites & vectors

Avec: Mirna Samara Dié Alves , Raquel Nascimento das Neves , Ângela Sena-Lopes , Micaela Domingues , Natália Vieira Segatto , Thaís Cristina Mendonça Nogueira , Marcus Vinicius Nora de Souza , Lucielli Savegnago , Fabiana Kömmling Seixas , Tiago Collares , Sibele Borsuk

2'-Hydroxychalcones as an alternative treatment for trichomoniasis in association with metronidazole.

Parasitology research

Avec: Raquel Nascimento das Neves , Ângela Sena-Lopes , Mirna Samara Dié Alves , Bárbara da Rocha Fonseca , Caroline Carapina da Silva , Lucielli Savegnago , Claudio Martin Pereira de Pereira , Daniela Fernandes Ramos , Sibele Borsuk

Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice.

Pharmacology, biochemistry, and behavior

Avec: Suely Ribeiro Bampi , Fernanda S Sabedra Sousa , Ana Paula Pesarico , Beatriz Vieira , Eder João Lenardão , Lucielli Savegnago

Depression-like behavior, hyperglycemia, oxidative stress, and neuroinflammation presented in diabetic mice are reversed by the administration of 1-methyl-3-(phenylselanyl)-1H-indole.

Journal of psychiatric research

Avec: Suely Ribeiro Bampi , Micaela Domingues , Darling de Andrade Lourenço , Ana Paula Pesarico , Beatriz Vieira , Karine Rech Begnini , Fabiana K Seixas , Tiago Veiras Collares , Eder João Lenardão , Lucielli Savegnago

Neuropharmacology of Organoselenium Compounds in Mental Disorders and Degenerative Diseases.

Current medicinal chemistry

Avec: Paloma T Birmann , Angela M Casaril , Laura Abenante , Filipe Penteado , César A Brüning , Lucielli Savegnago , Eder J Lenardão

Synthesis, characterization, antioxidant potential, and cytotoxicity screening of new Cu(II) complexes with 4-(arylchalcogenyl)-1H-pyrazoles ligands.

Journal of inorganic biochemistry

Avec: Adriana C Pinheiro , Franciele F Busatto , Bruna T Schaefer , Paula P Tomasini , Ianka J Nunes , Tamara Dos S Machado , Roberta Cargnelutti , Thalita F B de Aquino , Kethlin De Q Ferreira , Angela M Casaril , Raquel G Jacob , Lucielli Savegnago , Daniela Hartwig , Jenifer Saffi

Live Imaging of the Mitochondrial Glutathione Redox State in Primary Neurons using a Ratiometric Indicator.

Journal of visualized experiments : JoVE

Avec: Athanasios Katsalifis , Constanze Depp , Carlos Bas-Orth

Activated glia cells cause bioenergetic impairment of neurons that can be rescued by knock-down of the mitochondrial calcium uniporter.

Biochemical and biophysical research communications

Avec: Athanasios Katsalifis , Rolf M Schmidt , Carlos Bas-Orth

Neuronal Mitochondrial Dysfunction and Bioenergetic Failure in Inflammation-Associated Depression.

Frontiers in neuroscience

Avec: Robert Dantzer , Carlos Bas-Orth

The selenium-containing compound 3-((4-chlorophenyl)selanyl)-1-methyl-1H-indole reverses depressive-like behavior induced by acute restraint stress in mice: modulation of oxido-nitrosative stress and inflammatory pathway.

Psychopharmacology

Avec: Micaela Domingues , Suely Ribeiro Bampi , Darling de Andrade Lourenço , Nathalia Batista Padilha , Eder João Lenardão , Mariana Sonego , Fabiana Kommling Seixas , Tiago Collares , Cristina Wayne Nogueira , Robert Dantzer , Lucielli Savegnago

3-[(4-chlorophenyl)selanyl]-1-methyl-1H-indole ameliorates long-lasting depression- and anxiogenic-like behaviors and cognitive impairment in post-septic mice: Involvement of neuroimmune and oxidative hallmarks.

Chemico-biological interactions

Avec: Micaela Domingues , Darling de Andrade Lourenço , Beatriz Vieira , Karine Begnini , Carine Dahl Corcini , Raqueli Teresinha França , Antônio Sergio Varela Junior , Fabiana Kӧmmling Seixas , Tiago Collares , Eder João Lenardão , Lucielli Savegnago

Flower essential oil of Tagetes minuta mitigates oxidative stress and restores BDNF-Akt/ERK2 signaling attenuating inflammation- and stress-induced depressive-like behavior in mice.

Brain research

Avec: Paloma T Birmann , Angela M Casaril , Giuliana P Zugno , Gabriela G Acosta , Fernanda Severo Sabedra Sousa , Tiago Collares , Fabiana K Seixas , Raquel G Jacob , César A Brüning , Lucielli Savegnago , Daniela Hartwig

Anhedonic- and anxiogenic-like behaviors and neurochemical alterations are abolished by a single administration of a selenium-containing compound in chronically stressed mice.

Comprehensive psychoneuroendocrinology

Avec: Darling de Andrade Lourenço , Micaela Domingues , Thiago Ângelo Smaniotto , Paloma Taborda Birmann , Beatriz Vieira , Mariana Souza Sonego , Fabiana Kömmling Seixas , Tiago Collares , Eder João Lenardão , Lucielli Savegnago

Komagataella pastoris KM71H Mitigates Depressive-Like Phenotype, Preserving Intestinal Barrier Integrity and Modulating the Gut Microbiota in Mice.

Molecular neurobiology

Avec: Paloma T Birmann , Angela M Casaril , Ana Paula Pesarico , Rafael R Rodrigues , Fabricio R Conceição , Fernanda Severo Sabedra Sousa , Tiago Collares , Fabiana K Seixas , Lucielli Savegnago

Réseau de co-auteurs

Lucielli Savegnago 23 collaborations

Tiago Collares 14 collaborations

Micaela Domingues 13 collaborations

Eder João Lenardão 11 collaborations

Fabiana K Seixas 10 collaborations

Darling de Andrade Lourenço 9 collaborations

Beatriz Vieira 9 collaborations

Angela M Casaril 8 collaborations

Suely Ribeiro Bampi 7 collaborations

Paloma T Birmann 6 collaborations

Paloma Taborda Birmann 5 collaborations

Thiago Ângelo Smaniotto 4 collaborations

Ana Paula Pesarico 4 collaborations

Daniela Hartwig 4 collaborations

Raquel G Jacob 4 collaborations

Robert Dantzer 3 collaborations

Mirna Samara Dié Alves 3 collaborations

Ângela Sena-Lopes 3 collaborations

Raquel Nascimento das Neves 3 collaborations

Sibele Borsuk 3 collaborations

Carlos Bas-Orth 3 collaborations

Eder J Lenardão 2 collaborations

Mariana Sonego 2 collaborations

Karine Rech Begnini 2 collaborations

Tiago Veiras Collares 2 collaborations

Natália Segatto 2 collaborations

Fernanda S S Sousa 2 collaborations

Natália Vieira Segatto 2 collaborations

Karine Begnini 2 collaborations

Fabiana Kommling Seixas 2 collaborations

Thiago Â Smaniotto 2 collaborations

Rafael R Rodrigues 2 collaborations

Fabricio R Conceição 2 collaborations

Marcus Vinicius Nora de Souza 2 collaborations

Fabiana Kömmling Seixas 2 collaborations

César A Brüning 2 collaborations

Athanasios Katsalifis 2 collaborations

Fernanda Severo Sabedra Sousa 2 collaborations

Beatriz M Vieira 1 collaboration

Luiz H Dapper 1 collaboration

César Augusto Brüning 1 collaboration

Mariana G Fronza 1 collaboration

Lucas Simões 1 collaboration

Júlia Paschoal 1 collaboration

Júlia Damé Fonseca Paschoal 1 collaboration

Isadora André Lopes 1 collaboration

Morgana Alves Borges 1 collaboration

Ana Laura Feijó 1 collaboration

Lucas Damé Simões 1 collaboration

Vinicius Farias Campos 1 collaboration

Fabiana Seixas 1 collaboration

Nathalia Padilha 1 collaboration

Elisabeth G Vichaya 1 collaboration

M Raafay Rishi 1 collaboration

Bianca G Ford 1 collaboration

Pamela S Caballero 1 collaboration

Ângela N Moreira 1 collaboration

Raqueli T França 1 collaboration

Carine D Corcini 1 collaboration

Emerson Teixeira da Silva 1 collaboration

Fernanda S Sousa 1 collaboration

Rafael Woloski 1 collaboration

Luciano da Silva Pinto 1 collaboration

Diego Alves 1 collaboration

Thaís Cristina Mendonça Nogueira 1 collaboration

Bárbara da Rocha Fonseca 1 collaboration

Caroline Carapina da Silva 1 collaboration

Claudio Martin Pereira de Pereira 1 collaboration

Daniela Fernandes Ramos 1 collaboration

Fernanda S Sabedra Sousa 1 collaboration

Laura Abenante 1 collaboration

Filipe Penteado 1 collaboration

Adriana C Pinheiro 1 collaboration

Franciele F Busatto 1 collaboration

Bruna T Schaefer 1 collaboration

Paula P Tomasini 1 collaboration

Ianka J Nunes 1 collaboration

Tamara Dos S Machado 1 collaboration

Roberta Cargnelutti 1 collaboration

Thalita F B de Aquino 1 collaboration

Kethlin De Q Ferreira 1 collaboration

Jenifer Saffi 1 collaboration

Constanze Depp 1 collaboration

Rolf M Schmidt 1 collaboration

Nathalia Batista Padilha 1 collaboration

Cristina Wayne Nogueira 1 collaboration

Carine Dahl Corcini 1 collaboration

Raqueli Teresinha França 1 collaboration

Antônio Sergio Varela Junior 1 collaboration

Fabiana Kӧmmling Seixas 1 collaboration

Giuliana P Zugno 1 collaboration

Gabriela G Acosta 1 collaboration

Mariana Souza Sonego 1 collaboration