Ali Zeaiter

Affiliations

Clinical Development, PharmaMar, Madrid, 28770, Spain.

Publications (20)

Lurbinectedin in the treatment of relapsed small cell lung cancer.

Future oncology (London, England)

Avec: Javier Baena , Andrea Modrego , Carmen Kahatt , Vicente Alfaro , Elizabeth Jimenez-Aguilar , Jose María Mazarico , Luis Paz-Ares

Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases.

Lung cancer (Amsterdam, Netherlands)

Avec: Solange Peters , José Trigo , Benjamin Besse , Victor Moreno , Alejandro Navarro , Maria Eugenia Olmedo , Luis Paz-Ares , Christian Grohé , José Antonio Lopez-Vilariño , Cristian Fernández , Carmen Kahatt , Vicente Alfaro , Antonio Nieto , Vivek Subbiah

Efficacy and safety of lurbinectedin and doxorubicin in relapsed small cell lung cancer. Results from an expansion cohort of a phase I study.

Investigational new drugs

Avec: María Eugenia Olmedo , Martin Forster , Victor Moreno , María Pilar López-Criado , Irene Braña , Michael Flynn , Bernard Doger , María de Miguel , José Antonio López-Vilariño , Rafael Núñez , Carmen Kahatt , Martin Cullell-Young , Emiliano Calvo

Lurbinectedin, a selective inhibitor of oncogenic transcription, in patients with pretreated germline BRCA1/2 metastatic breast cancer: results from a phase II basket study.

ESMO open

Avec: V Boni , B Pistilli , I Braña , G I Shapiro , J Trigo , V Moreno , D Castellano , C Fernández , C Kahatt , V Alfaro , M Siguero , A Zeaiter , F Longo , K Zaman , A Antón , A Paredes , G Huidobro , V Subbiah

Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial.

The Lancet. Respiratory medicine

Avec: Santiago Ponce Aix , Tudor Eliade Ciuleanu , Alejandro Navarro , Sophie Cousin , Laura Bonanno , Egbert F Smit , Alberto Chiappori , Maria Eugenia Olmedo , Ildiko Horvath , Christian Grohé , Anna F Farago , José Antonio López-Vilariño , Martin Cullell-Young , Antonio Nieto , Noelia Vasco , Javier Gómez , Carmen Kahatt , Enric Carcereny , Jaromir Roubec , Konstantinos Syrigos , Gregory Lo , Isidoro Barneto , Anthony Pope , Amparo Sánchez , Joseph Kattan , Konstantinos Zarogoulidis , Cornelius F Waller , Helge Bischoff , Oscar Juan-Vidal , Niels Reinmuth , Manuel Dómine , Luis Paz-Ares

Anti-cancer drug combinations approved by US FDA from 2011 to 2021: main design features of clinical trials and role of pharmacokinetics.

Cancer chemotherapy and pharmacology

Avec: Salvador Fudio , Alvaro Sellers , Laura Pérez Ramos , Beatriz Gil-Alberdi , Mikel Urroz , Antonio Carcas , Rubin Lubomirov

Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study.

Investigational new drugs

Avec: Rebecca Kristeleit , Alexandra Leary , Jean Pierre Delord , Victor Moreno , Ana Oaknin , Daniel Castellano , Geoffrey I Shappiro , Cristian Fernández , Carmen Kahatt , Vicente Alfaro , Mariano Siguero , Daniel Rueda , Ahmad Awada , Ana Santaballa , Khalil Zaman , Jalid Sehouli , Vivek Subbiah

Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial.

The Lancet. Oncology

Avec: José Trigo , Vivek Subbiah , Benjamin Besse , Victor Moreno , Rafael López , María Angeles Sala , Solange Peters , Santiago Ponce , Cristian Fernández , Vicente Alfaro , Javier Gómez , Carmen Kahatt , Khalil Zaman , Valentina Boni , Jennifer Arrondeau , Maite Martínez , Jean-Pierre Delord , Ahmad Awada , Rebecca Kristeleit , Maria Eugenia Olmedo , Luciano Wannesson , Javier Valdivia , María Jesús Rubio , Antonio Anton , John Sarantopoulos , Sant P Chawla , Joaquín Mosquera-Martinez , Manolo D'Arcangelo , Armando Santoro , Victor M Villalobos , Jacob Sands , Luis Paz-Ares

Antitumor activity of lurbinectedin in second-line small cell lung cancer patients who are candidates for re-challenge with the first-line treatment.

Lung cancer (Amsterdam, Netherlands)

Avec: Vivek Subbiah , Luis Paz-Ares , Benjamin Besse , Victor Moreno , Solange Peters , María Angeles Sala , José Antonio López-Vilariño , Cristian Fernández , Carmen Kahatt , Vicente Alfaro , Mariano Siguero , Khalil Zaman , Rafael López , Santiago Ponce , Valentina Boni , Jennifer Arrondeau , Jean-Pierre Delord , Maite Martínez , Luciano Wannesson , Antonio Antón , Javier Valdivia , Ahmad Awada , Rebecca Kristeleit , Maria Eugenia Olmedo , María Jesús Rubio , John Sarantopoulos , Sant P Chawla , Joaquín Mosquera-Martinez , Manolo D' Arcangelo , Armando Santoro , Victor M Villalobos , Jacob Sands , José Trigo

Doxorubicin plus lurbinectedin in patients with advanced endometrial cancer: results from an expanded phase I study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Avec: Rebecca Kristeleit , Victor Moreno , Valentina Boni , Eva M Guerra , Carmen Kahatt , Ignacio Romero , Emiliano Calvo , Neus Basté , José A López-Vilariño , Mariano Siguero , Vicente Alfaro , Martin Forster

Pooled Safety Analysis of Single-Agent Lurbinectedin in Patients With Advanced Solid Tumours.

European journal of cancer (Oxford, England : 1990)

Avec: Alexandra Leary , Ana Oaknin , José Manuel Trigo , Victor Moreno , Jean-Pierre Delord , Valentina Boni , Irene Braña , Cristian Fernández , Carmen Kahatt , Antonio Nieto , Martin Cullell-Young , Vivek Subbiah

Impact of a Moderate CYP3A4 Inducer (Bosentan) on Lurbinectedin Pharmacokinetics and Safety in Patients with Advanced Solid Tumors: An Open-Label, Two-Way, Crossover, Phase Ib Drug-Drug Interaction Study.

Pharmaceuticals (Basel, Switzerland)

Avec: Irene Moreno , Tatiana Hernández , Emiliano Calvo , Salvador Fudio , Carmen Kahatt , Cristian Fernández , Jorge Luis Iglesias , Gema Corral , Laura Pérez-Ramos , Lola Montilla , Rubin Lubomirov

A phase I trial of lurbinectedin in combination with cisplatin in patients with advanced solid tumors.

Investigational new drugs

Avec: Yannis Metaxas , Carmen Kahatt , Vicente Alfaro , Salvador Fudio , Ruth Plummer , Cristiana Sessa , Roger Von Moos , Martin Forster , Anastasios Stathis

Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma.

Cancer medicine

Avec: María Victoria Mateos , Felipe Prosper , Jesús Martin Sánchez , Enrique M Ocio , Albert Oriol , Cristina Motlló , Jean-Marie Michot , Isidro Jarque , Rebeca Iglesias , María Solé , Sara Martínez , Carmen Kahatt , Salvador Fudio , Gema Corral , Lola Montilla , Vincent Ribrag

A model-based head-to-head comparison of single-agent lurbinectedin in the pivotal ATLANTIS Study.

Frontiers in oncology

Avec: Salvador Fudio , Laura Pérez-Ramos , Eduardo Asín-Prieto , Rubin Lubomirov

Pharmacokinetics and Safety of Lurbinectedin Administrated with Itraconazole in Cancer Patients: A Drug-Drug Interaction Study.

Marine drugs

Avec: Irene Moreno , Tatiana Hernández , Emiliano Calvo , Salvador Fudio , Carmen Kahatt , Sara Martínez , Jorge Luis Iglesias , Román Octavio Calafati , Laura Pérez-Ramos , Lola Montilla , Rubin Lubomirov

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.

Drug metabolism and disposition: the biological fate of chemicals

Avec: P Aviles , R Altares , L van Andel , R Lubomirov , S Fudio , H Rosing , F M Márquez Del Pino , M M Tibben , G Benedit , L Nan-Offeringa , X E Luepke Estefan , A Francesch , A Zeaiter , C Cuevas , J H M Schellens , J H Beijnen

Antitumor Activity of Lurbinectedin, a Selective Inhibitor of Oncogene Transcription, in Patients with Relapsed Ewing Sarcoma: Results of a Basket Phase II Study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Vivek Subbiah , Irene Braña , Alessandra Longhi , Valentina Boni , Jean-Pierre Delord , Ahmad Awada , Pascaline Boudou-Rouquette , John Sarantopoulos , Geoffrey I Shapiro , Anthony Elias , Ravin Ratan , Cristian Fernandez , Carmen Kahatt , Martin Cullell-Young , Mariano Siguero , Sant P Chawla

Lurbinectedin versus pegylated liposomal doxorubicin or topotecan in patients with platinum-resistant ovarian cancer: A multicenter, randomized, controlled, open-label phase 3 study (CORAIL).

Gynecologic oncology

Avec: Stephanie Gaillard , Ana Oaknin , Isabelle Ray-Coquard , Ignace Vergote , Giovanni Scambia , Nicoletta Colombo , Cristian Fernandez , Vicente Alfaro , Carmen Kahatt , Antonio Nieto , Miguel Aracil , Laura Vidal , Beatriz Pardo-Burdalo , Zsuzsanna Papai , Rebecca Kristeleit , David M O'Malley , Ivor Benjamin , Patricia Pautier , Domenica Lorusso

Lurbinectedin in patients with pretreated neuroendocrine tumours: Results from a phase II basket study.

European journal of cancer (Oxford, England : 1990)

Avec: Federico Longo-Muñoz , Daniel Castellano , Jerome Alexandre , Sant P Chawla , Cristian Fernández , Carmen Kahatt , Vicente Alfaro , Mariano Siguero , Victor Moreno , Enrique Sanz-García , Ahmad Awada , Ana Santaballa , Vivek Subbiah

Réseau de co-auteurs

Carmen Kahatt 16 collaborations

Vicente Alfaro 9 collaborations

Victor Moreno 8 collaborations

Cristian Fernández 7 collaborations

Vivek Subbiah 7 collaborations

Salvador Fudio 6 collaborations

Luis Paz-Ares 5 collaborations

Rebecca Kristeleit 5 collaborations

Mariano Siguero 5 collaborations

Ahmad Awada 5 collaborations

Valentina Boni 5 collaborations

Maria Eugenia Olmedo 4 collaborations

Antonio Nieto 4 collaborations

Martin Cullell-Young 4 collaborations

Emiliano Calvo 4 collaborations

Rubin Lubomirov 4 collaborations

Jean-Pierre Delord 4 collaborations

Sant P Chawla 4 collaborations

Solange Peters 3 collaborations

José Trigo 3 collaborations

Benjamin Besse 3 collaborations

Martin Forster 3 collaborations

Irene Braña 3 collaborations

José Antonio López-Vilariño 3 collaborations

Ana Oaknin 3 collaborations

Khalil Zaman 3 collaborations

John Sarantopoulos 3 collaborations

Laura Pérez-Ramos 3 collaborations

Lola Montilla 3 collaborations

Alejandro Navarro 2 collaborations

Christian Grohé 2 collaborations

A Zeaiter 2 collaborations

Javier Gómez 2 collaborations

Alexandra Leary 2 collaborations

Daniel Castellano 2 collaborations

Ana Santaballa 2 collaborations

Rafael López 2 collaborations

María Angeles Sala 2 collaborations

Santiago Ponce 2 collaborations

Jennifer Arrondeau 2 collaborations

Maite Martínez 2 collaborations

Luciano Wannesson 2 collaborations

Javier Valdivia 2 collaborations

María Jesús Rubio 2 collaborations

Joaquín Mosquera-Martinez 2 collaborations

Armando Santoro 2 collaborations

Victor M Villalobos 2 collaborations

Jacob Sands 2 collaborations

Irene Moreno 2 collaborations

Tatiana Hernández 2 collaborations

Jorge Luis Iglesias 2 collaborations

Gema Corral 2 collaborations

Sara Martínez 2 collaborations

Cristian Fernandez 2 collaborations

Javier Baena 1 collaboration

Andrea Modrego 1 collaboration

Elizabeth Jimenez-Aguilar 1 collaboration

Jose María Mazarico 1 collaboration

José Antonio Lopez-Vilariño 1 collaboration

María Eugenia Olmedo 1 collaboration

María Pilar López-Criado 1 collaboration

Michael Flynn 1 collaboration

Bernard Doger 1 collaboration

María de Miguel 1 collaboration

Rafael Núñez 1 collaboration

V Boni 1 collaboration

B Pistilli 1 collaboration

I Braña 1 collaboration

G I Shapiro 1 collaboration

J Trigo 1 collaboration

V Moreno 1 collaboration

D Castellano 1 collaboration

C Fernández 1 collaboration

C Kahatt 1 collaboration

V Alfaro 1 collaboration

M Siguero 1 collaboration

F Longo 1 collaboration

K Zaman 1 collaboration

A Antón 1 collaboration

A Paredes 1 collaboration

G Huidobro 1 collaboration

V Subbiah 1 collaboration

Santiago Ponce Aix 1 collaboration

Tudor Eliade Ciuleanu 1 collaboration

Sophie Cousin 1 collaboration

Laura Bonanno 1 collaboration

Egbert F Smit 1 collaboration

Alberto Chiappori 1 collaboration

Ildiko Horvath 1 collaboration

Anna F Farago 1 collaboration

Noelia Vasco 1 collaboration

Enric Carcereny 1 collaboration

Jaromir Roubec 1 collaboration

Konstantinos Syrigos 1 collaboration

Gregory Lo 1 collaboration

Isidoro Barneto 1 collaboration

Anthony Pope 1 collaboration

Amparo Sánchez 1 collaboration

Joseph Kattan 1 collaboration

Konstantinos Zarogoulidis 1 collaboration

Cornelius F Waller 1 collaboration

Helge Bischoff 1 collaboration

Oscar Juan-Vidal 1 collaboration

Niels Reinmuth 1 collaboration

Manuel Dómine 1 collaboration

Alvaro Sellers 1 collaboration

Laura Pérez Ramos 1 collaboration

Beatriz Gil-Alberdi 1 collaboration

Mikel Urroz 1 collaboration

Antonio Carcas 1 collaboration

Jean Pierre Delord 1 collaboration

Geoffrey I Shappiro 1 collaboration

Daniel Rueda 1 collaboration

Jalid Sehouli 1 collaboration

Antonio Anton 1 collaboration

Manolo D'Arcangelo 1 collaboration

Antonio Antón 1 collaboration

Manolo D' Arcangelo 1 collaboration

Eva M Guerra 1 collaboration

Ignacio Romero 1 collaboration

Neus Basté 1 collaboration

José A López-Vilariño 1 collaboration

José Manuel Trigo 1 collaboration

Yannis Metaxas 1 collaboration

Ruth Plummer 1 collaboration

Cristiana Sessa 1 collaboration

Roger Von Moos 1 collaboration

Anastasios Stathis 1 collaboration

María Victoria Mateos 1 collaboration

Felipe Prosper 1 collaboration

Jesús Martin Sánchez 1 collaboration

Enrique M Ocio 1 collaboration

Albert Oriol 1 collaboration

Cristina Motlló 1 collaboration

Jean-Marie Michot 1 collaboration

Isidro Jarque 1 collaboration

Rebeca Iglesias 1 collaboration

María Solé 1 collaboration

Vincent Ribrag 1 collaboration

Eduardo Asín-Prieto 1 collaboration

Román Octavio Calafati 1 collaboration

P Aviles 1 collaboration

R Altares 1 collaboration

L van Andel 1 collaboration

R Lubomirov 1 collaboration

S Fudio 1 collaboration

H Rosing 1 collaboration

F M Márquez Del Pino 1 collaboration

M M Tibben 1 collaboration

G Benedit 1 collaboration

L Nan-Offeringa 1 collaboration

X E Luepke Estefan 1 collaboration

A Francesch 1 collaboration

C Cuevas 1 collaboration

J H M Schellens 1 collaboration

J H Beijnen 1 collaboration

Alessandra Longhi 1 collaboration

Pascaline Boudou-Rouquette 1 collaboration

Geoffrey I Shapiro 1 collaboration

Anthony Elias 1 collaboration

Ravin Ratan 1 collaboration

Stephanie Gaillard 1 collaboration

Isabelle Ray-Coquard 1 collaboration

Ignace Vergote 1 collaboration

Giovanni Scambia 1 collaboration

Nicoletta Colombo 1 collaboration

Miguel Aracil 1 collaboration

Laura Vidal 1 collaboration

Beatriz Pardo-Burdalo 1 collaboration

Zsuzsanna Papai 1 collaboration

David M O'Malley 1 collaboration

Ivor Benjamin 1 collaboration

Patricia Pautier 1 collaboration

Domenica Lorusso 1 collaboration

Federico Longo-Muñoz 1 collaboration

Jerome Alexandre 1 collaboration

Enrique Sanz-García 1 collaboration