Alexia F Kalogeropulou

Affiliations

Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom.

ORCID: 0000-0001-5185-7694

Publications (3)

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2.

Journal of the American Chemical Society

Avec: Xingui Liu , Sofia Domingos , Nikolai Makukhin , Raja S Nirujogi , Francois Singh , Natalia Shpiro , Anton Saalfrank , Esther Sammler , Ian G Ganley , Rui Moreira , Dario R Alessi , Alessio Ciulli

Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.

The Biochemical journal

Avec: Jordana B Freemantle , Pawel Lis , Edmundo G Vides , Nicole K Polinski , Dario R Alessi

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding.

The Biochemical journal

Avec: Elena Purlyte , Francesca Tonelli , Sven M Lange , Melanie Wightman , Alan R Prescott , Shalini Padmanabhan , Esther Sammler , Dario R Alessi

Réseau de co-auteurs

Dario R Alessi 3 collaborations

Esther Sammler 2 collaborations

Xingui Liu 1 collaboration

Sofia Domingos 1 collaboration

Nikolai Makukhin 1 collaboration

Raja S Nirujogi 1 collaboration

Francois Singh 1 collaboration

Natalia Shpiro 1 collaboration

Anton Saalfrank 1 collaboration

Ian G Ganley 1 collaboration

Rui Moreira 1 collaboration

Alessio Ciulli 1 collaboration

Jordana B Freemantle 1 collaboration

Pawel Lis 1 collaboration

Edmundo G Vides 1 collaboration

Nicole K Polinski 1 collaboration

Elena Purlyte 1 collaboration

Francesca Tonelli 1 collaboration

Sven M Lange 1 collaboration

Melanie Wightman 1 collaboration

Alan R Prescott 1 collaboration

Shalini Padmanabhan 1 collaboration