Alexandra Piunti

Affiliations

Section of Cell Biology and Functional Genomics, Imperial College London, du Cane Road, London, W12 0NN, UK; Lille 1 University-Science and Technology, Cité Scientifique, 59655, Villeneuve d'Ascq Cedex, France.

Publications (16)

A small UTX stabilization domain of Trr is conserved within mammalian MLL3-4/COMPASS and is sufficient to rescue loss of viability in null animals.

Genes & development

Avec: Ryan Rickels , Lu Wang , Marta Iwanaszko , Patrick A Ozark , Marc A Morgan , Andrea Piunti , Natalia Khalatyan , Shimaa H A Soliman , Emily J Rendleman , Jeffrey N Savas , Edwin R Smith , Ali Shilatifard

Role of Chromatin Modifying Complexes and Therapeutic Opportunities in Bladder Cancer.

Bladder cancer (Amsterdam, Netherlands)

Avec: Khyati Meghani , Lauren Folgosa Cooley , Andrea Piunti , Joshua J Meeks

5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma.

JCO precision oncology

Avec: Mohansrinivas Chennakesavalu , Kelley Moore , Gepoliano Chaves , Sahil Veeravalli , Rachel TerHaar , Tong Wu , Ruitu Lyu , Alexandre Chlenski , Chuan He , Andrea Piunti , Mark A Applebaum

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis.

Molecular metabolism

Avec: Gaelle R Carrat , Elizabeth Haythorne , Alejandra Tomas , Leena Haataja , Andreas Müller , Peter Arvan , Kaiying Cheng , Mutian Huang , Timothy J Pullen , Eleni Georgiadou , Theodoros Stylianides , Nur Shabrina Amirruddin , Victoria Salem , Walter Distaso , Andrew Cakebread , Kate J Heesom , Philip A Lewis , David J Hodson , Linford J Briant , Annie C H Fung , Richard B Sessions , Fabien Alpy , Alice P S Kong , Peter I Benke , Federico Torta , Adrian Kee Keong Teo , Isabelle Leclerc , Michele Solimena , Dale B Wigley , Guy A Rutter

The roles of Polycomb repressive complexes in mammalian development and cancer.

Nature reviews. Molecular cell biology

Avec: Andrea Piunti , Ali Shilatifard

Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells.

Acta neuropathologica communications

Avec: Tina Yi-Ting Huang , Andrea Piunti , Jin Qi , Marc Morgan , Elizabeth Bartom , Ali Shilatifard , Amanda M Saratsis

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.

Science advances

Avec: Andrea Piunti , Edwin R Smith , Marc A J Morgan , Michal Ugarenko , Natalia Khaltyan , Kathryn A Helmin , Caila A Ryan , David C Murray , Ryan A Rickels , Bahar D Yilmaz , Emily J Rendleman , Jeffrey N Savas , Benjamin D Singer , Serdar E Bulun , Ali Shilatifard

Epigenetic reprogramming of host and viral genes by Human Cytomegalovirus infection in Kasumi-3 myeloid progenitor cells at early times post-infection.

Journal of virology

Avec: Eleonora Forte , Fatma Ayaloglu Butun , Christian Marinaccio , Matthew J Schipma , Andrea Piunti , Mark W Schroeder , Manoj Kandpal , Ali Shilatifard , Michael Abecassis , Mary Hummel

Decoding the protein composition of whole nucleosomes with Nuc-MS.

Nature methods

Avec: Luis F Schachner , Kevin Jooß , Marc A Morgan , Andrea Piunti , Matthew J Meiners , Jared O Kafader , Alexander S Lee , Marta Iwanaszko , Marcus A Cheek , Jonathan M Burg , Sarah A Howard , Michael-Christopher Keogh , Ali Shilatifard , Neil L Kelleher

Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma.

Science advances

Avec: Andrea Piunti , Khyati Meghani , Yanni Yu , A Gordon Robertson , Joseph R Podojil , Kimberly A McLaughlin , Zonghao You , Damiano Fantini , MingYi Chiang , Yi Luo , Lu Wang , Nathan Heyen , Jun Qian , Stephen D Miller , Ali Shilatifard , Joshua J Meeks

PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing.

Molecular cell

Avec: Ka-Wing Fong , Jonathan C Zhao , Xiaodong Lu , Jung Kim , Andrea Piunti , Ali Shilatifard , Jindan Yu

Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.

Nature genetics

Avec: Delphine Douillet , Christie C Sze , Caila Ryan , Andrea Piunti , Avani P Shah , Michal Ugarenko , Stacy A Marshall , Emily J Rendleman , Didi Zha , Kathryn A Helmin , Zibo Zhao , Kaixiang Cao , Marc A Morgan , Benjamin D Singer , Elizabeth T Bartom , Edwin R Smith , Ali Shilatifard

Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Hiroaki Katagi , Nundia Louis , Dusten Unruh , Takahiro Sasaki , Xingyao He , Ali Zhang , Quanhong Ma , Andrea Piunti , Yosuke Shimazu , Jonathan B Lamano , Angel M Carcaboso , Xiao Tian , Andrei Seluanov , Vera Gorbunova , Kathryn L Laurie , Akihide Kondo , Nitin R Wadhwani , Rishi Lulla , Stewart Goldman , Sriram Venneti , Oren J Becher , Lihua Zou , Ali Shilatifard , Rintaro Hashizume

Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumors.

Molecular cancer therapeutics

Avec: Yukitomo Ishi , Yongzhan Zhang , Ali Zhang , Takahiro Sasaki , Andrea Piunti , Amreena Suri , Jun Watanabe , Kouki Abe , Xingyao He , Hiroaki Katagi , Pankaj Bhalla , Manabu Natsumeda , Lihua Zou , Ali Shilatifard , Rintaro Hashizume

5-hydroxymethylcytosine profiling of cell-free DNA identifies bivalent genes that are prognostic of survival in high-risk neuroblastoma.

bioRxiv : the preprint server for biology

Avec: Mohansrinivas Chennakesavalu , Kelley Moore , Gepoliano Chaves , Sahil Veeravalli , Rachel TerHaar , Tong Wu , Ruitu Lyu , Alexandre Chlenski , Chuan He , Andrea Piunti , Mark A Applebaum

Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in Ori

Microbiology spectrum

Avec: Eleonora Forte , Ming Li , Fatma Ayaloglu Butun , Qiaolin Hu , Eva Maria Borst , Matthew J Schipma , Andrea Piunti , Ali Shilatifard , Scott S Terhune , Michael Abecassis , Jeffery L Meier , Mary Hummel

Réseau de co-auteurs

Andrea Piunti 15 collaborations

Ali Shilatifard 12 collaborations

Marc A Morgan 3 collaborations

Emily J Rendleman 3 collaborations

Edwin R Smith 3 collaborations

Lu Wang 2 collaborations

Marta Iwanaszko 2 collaborations

Jeffrey N Savas 2 collaborations

Khyati Meghani 2 collaborations

Joshua J Meeks 2 collaborations

Mohansrinivas Chennakesavalu 2 collaborations

Kelley Moore 2 collaborations

Gepoliano Chaves 2 collaborations

Sahil Veeravalli 2 collaborations

Rachel TerHaar 2 collaborations

Tong Wu 2 collaborations

Ruitu Lyu 2 collaborations

Alexandre Chlenski 2 collaborations

Chuan He 2 collaborations

Mark A Applebaum 2 collaborations

Michal Ugarenko 2 collaborations

Kathryn A Helmin 2 collaborations

Benjamin D Singer 2 collaborations

Eleonora Forte 2 collaborations

Fatma Ayaloglu Butun 2 collaborations

Matthew J Schipma 2 collaborations

Michael Abecassis 2 collaborations

Mary Hummel 2 collaborations

Hiroaki Katagi 2 collaborations

Takahiro Sasaki 2 collaborations

Xingyao He 2 collaborations

Ali Zhang 2 collaborations

Lihua Zou 2 collaborations

Rintaro Hashizume 2 collaborations

Ryan Rickels 1 collaboration

Patrick A Ozark 1 collaboration

Natalia Khalatyan 1 collaboration

Shimaa H A Soliman 1 collaboration

Lauren Folgosa Cooley 1 collaboration

Gaelle R Carrat 1 collaboration

Elizabeth Haythorne 1 collaboration

Alejandra Tomas 1 collaboration

Leena Haataja 1 collaboration

Andreas Müller 1 collaboration

Peter Arvan 1 collaboration

Kaiying Cheng 1 collaboration

Mutian Huang 1 collaboration

Timothy J Pullen 1 collaboration

Eleni Georgiadou 1 collaboration

Theodoros Stylianides 1 collaboration

Nur Shabrina Amirruddin 1 collaboration

Victoria Salem 1 collaboration

Walter Distaso 1 collaboration

Andrew Cakebread 1 collaboration

Kate J Heesom 1 collaboration

Philip A Lewis 1 collaboration

David J Hodson 1 collaboration

Linford J Briant 1 collaboration

Annie C H Fung 1 collaboration

Richard B Sessions 1 collaboration

Fabien Alpy 1 collaboration

Alice P S Kong 1 collaboration

Peter I Benke 1 collaboration

Federico Torta 1 collaboration

Adrian Kee Keong Teo 1 collaboration

Isabelle Leclerc 1 collaboration

Michele Solimena 1 collaboration

Dale B Wigley 1 collaboration

Guy A Rutter 1 collaboration

Tina Yi-Ting Huang 1 collaboration

Jin Qi 1 collaboration

Marc Morgan 1 collaboration

Elizabeth Bartom 1 collaboration

Amanda M Saratsis 1 collaboration

Marc A J Morgan 1 collaboration

Natalia Khaltyan 1 collaboration

Caila A Ryan 1 collaboration

David C Murray 1 collaboration

Ryan A Rickels 1 collaboration

Bahar D Yilmaz 1 collaboration

Serdar E Bulun 1 collaboration

Christian Marinaccio 1 collaboration

Mark W Schroeder 1 collaboration

Manoj Kandpal 1 collaboration

Luis F Schachner 1 collaboration

Kevin Jooß 1 collaboration

Matthew J Meiners 1 collaboration

Jared O Kafader 1 collaboration

Alexander S Lee 1 collaboration

Marcus A Cheek 1 collaboration

Jonathan M Burg 1 collaboration

Sarah A Howard 1 collaboration

Michael-Christopher Keogh 1 collaboration

Neil L Kelleher 1 collaboration

Yanni Yu 1 collaboration

A Gordon Robertson 1 collaboration

Joseph R Podojil 1 collaboration

Kimberly A McLaughlin 1 collaboration

Zonghao You 1 collaboration

Damiano Fantini 1 collaboration

MingYi Chiang 1 collaboration

Yi Luo 1 collaboration

Nathan Heyen 1 collaboration

Jun Qian 1 collaboration

Stephen D Miller 1 collaboration

Ka-Wing Fong 1 collaboration

Jonathan C Zhao 1 collaboration

Xiaodong Lu 1 collaboration

Jung Kim 1 collaboration

Jindan Yu 1 collaboration

Delphine Douillet 1 collaboration

Christie C Sze 1 collaboration

Caila Ryan 1 collaboration

Avani P Shah 1 collaboration

Stacy A Marshall 1 collaboration

Didi Zha 1 collaboration

Zibo Zhao 1 collaboration

Kaixiang Cao 1 collaboration

Elizabeth T Bartom 1 collaboration

Nundia Louis 1 collaboration

Dusten Unruh 1 collaboration

Quanhong Ma 1 collaboration

Yosuke Shimazu 1 collaboration

Jonathan B Lamano 1 collaboration

Angel M Carcaboso 1 collaboration

Xiao Tian 1 collaboration

Andrei Seluanov 1 collaboration

Vera Gorbunova 1 collaboration

Kathryn L Laurie 1 collaboration

Akihide Kondo 1 collaboration

Nitin R Wadhwani 1 collaboration

Rishi Lulla 1 collaboration

Stewart Goldman 1 collaboration

Sriram Venneti 1 collaboration

Oren J Becher 1 collaboration

Yukitomo Ishi 1 collaboration

Yongzhan Zhang 1 collaboration

Amreena Suri 1 collaboration

Jun Watanabe 1 collaboration

Kouki Abe 1 collaboration

Pankaj Bhalla 1 collaboration

Manabu Natsumeda 1 collaboration

Ming Li 1 collaboration

Qiaolin Hu 1 collaboration

Eva Maria Borst 1 collaboration

Scott S Terhune 1 collaboration

Jeffery L Meier 1 collaboration