Alex Toker

Affiliations

Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Publications (25)

The relation between ischemia modified albumin levels and carotid intima media thickness in patients with rheumatoid arthritis.

International journal of rheumatic diseases

Avec: Ali U Uslu , Adem Kucuk , Sevket Balta , Cengiz Ozturk , Sevket Arslan , Levent Tekin , Sami Kucuksen , Aysun Toker , Mehmet Kayrak

AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions.

Nature cell biology

Avec: Jianping Guo , Xiangpeng Dai , Benoit Laurent , Nana Zheng , Wenjian Gan , Jian Zhang , Ailan Guo , Min Yuan , Pengda Liu , John M Asara , Yang Shi , Pier Paolo Pandolfi , Wenyi Wei

Pulmonary Arterial Bypass Surgery for Fibrosing Mediastinitis Causing Severe Pulmonary Hypertension.

The Annals of thoracic surgery

Avec: Berk Cimenoglu , Berker Ozkan , Murat Basaran , Alper Toker

The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer.

Cancer discovery

Avec: Hui Liu , Marcia N Paddock , Haibin Wang , Charles J Murphy , Renee C Geck , Adrija J Navarro , Gerburg M Wulf , Olivier Elemento , Volker Haucke , Lewis C Cantley ,

Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.

The Journal of biological chemistry

Avec: Renee C Geck , Jackson R Foley , Tracy Murray Stewart , John M Asara , Robert A Casero ,

The Impact of Shift Type on Oxidative Stress, Inflammation, and Platelet Activation.

Journal of occupational and environmental medicine

Avec: Irfan Demir , Aysun Toker , Hulya Aksoy , Erkan Tasyurek , Selcuk Zengin

An antiquated contraindication for minimally invasive lung surgery: No place to staple the bronchus.

Turk gogus kalp damar cerrahisi dergisi

Avec: Tuğba Coşgun , Erkan Kaba , Kemal Ayalp , Alper Toker

An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.

Oncoimmunology

Avec: Alexander Muik , Isil Altintas , Friederike Gieseke , Kristina B Schoedel , Saskia M Burm , Aras Toker , Theodora W Salcedo , Dennis Verzijl , David Eisel , Christian Grunwitz , Lena M Kranz , Mathias Vormehr , David P E Satijn , Mustafa Diken , Sebastian Kreiter , Kate Sasser , Tahamtan Ahmadi , Özlem Türeci , Esther C W Breij , Maria Jure-Kunkel , Ugur Sahin

The procedure and effectiveness of release maneuvers in tracheobronchial resection and reconstruction.

Translational lung cancer research

Avec: Jiaxi He , Yunpeng Zhong , Hon-Chi Suen , Aditya Sengupta , Raghav A Murthy , Eirch Stoelben , Angelo Carretta , Alper Toker , Chudong Wang , Jianxing He , Shuben Li

Early trends in ECMO mortality during the first quarters of 2019 and 2020: Could we have predicted the onset of the pandemic?

Perfusion

Avec: J W Awori Hayanga , Jahnavi Kakuturu , Alper Toker , Fatima Asad , Anthony Siler , Heather Hayanga , Vinay Badhwar

Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice.

Science immunology

Avec: Alexander Muik , Bonny Gaby Lui , Maren Bacher , Ann-Kathrin Wallisch , Aras Toker , Carla Iris Cadima Couto , Alptekin Güler , Veena Mampilli , Geneva J Schmitt , Jonathan Mottl , Thomas Ziegenhals , Stephanie Fesser , Jonas Reinholz , Florian Wernig , Karla-Gerlinde Schraut , Hossam Hefesha , Hui Cai , Qi Yang , Kerstin C Walzer , Jessica Grosser , Stefan Strauss , Andrew Finlayson , Kimberly Krüger , Orkun Ozhelvaci , Katharina Grikscheit , Niko Kohmer , Sandra Ciesek , Kena A Swanson , Annette B Vogel , Özlem Türeci , Ugur Sahin

JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States.

Cancer research

Avec: Laura E Stevens , Guillermo Peluffo , Xintao Qiu , Daniel Temko , Anne Fassl , Zheqi Li , Anne Trinh , Marco Seehawer , Bojana Jovanović , Maša Alečković , Callahan M Wilde , Renee C Geck , Shaokun Shu , Natalie L Kingston , Nicholas W Harper , Vanessa Almendro , Alanna L Pyke , Shawn B Egri , Malvina Papanastasiou , Kendell Clement , Ningxuan Zhou , Sarah Walker , Jacqueline Salas , So Yeon Park , David A Frank , Alexander Meissner , Jacob D Jaffe , Piotr Sicinski , Franziska Michor , Henry W Long , Beth A Overmoyer , Kornelia Polyak

Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity.

Cell reports

Avec: Alexander Muik , Bonny Gaby Lui , Jasmin Quandt , Huitian Diao , Yunguan Fu , Maren Bacher , Jessica Gordon , Aras Toker , Jessica Grosser , Orkun Ozhelvaci , Katharina Grikscheit , Sebastian Hoehl , Niko Kohmer , Yaniv Lustig , Gili Regev-Yochay , Sandra Ciesek , Karim Beguir , Asaf Poran , Isabel Vogler , Özlem Türeci , Ugur Sahin

Minimally Invasive Repair of Adult Slipped Rib Syndrome Without Costal Cartilage Excision.

The Annals of thoracic surgery

Avec: Adam J Hansen , Alper Toker , Jeremiah Hayanga , Percival Buenaventura , Charlotte Spear , Ghulam Abbas

Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia.

PloS one

Avec: Emily B Cohen , Renee C Geck ,

Successful Sleeve Resection as a Marker for Proficiency for Robotic Pulmonary Resection.

The Thoracic and cardiovascular surgeon

Avec: Tugba Cosgun , Erkan Kaba , Kemal Ayalp , Alper Toker

Effectiveness of Video-Assisted Thoracoscopic Surgery in Undiagnosed Exudative Pleural Effusions.

Turkish thoracic journal

Avec: Erdoğan Dadaş , Eren Erdoğdu , Alper Toker , Miray Ersöz , Tamer Okay

Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer.

Oncoimmunology

Avec: Heather L MacGregor , Carlos Garcia-Batres , Azin Sayad , Andrew Elia , Hal K Berman , Aras Toker , Sarah Rachel Katz , Patricia A Shaw , Blaise A Clarke , Sarah Q Crome , Celine Robert-Tissot , Marcus Q Bernardini , Linh T Nguyen , Pamela S Ohashi

Can Improved Use of Biomarkers Alter the Fate of PI3K Pathway Inhibitors in the Clinic?

Cancer research

Avec: Emily C Erickson ,

Difficult Decisions in Minimally Invasive Surgery of the Thymus.

Cancers

Avec: Ankit Dhamija , Jahnavi Kakuturu , J W Awori Hayanga , Alper Toker

Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype.

PLoS genetics

Avec: Ralitsa R Madsen , Emily C Erickson , Oscar M Rueda , Xavier Robin , Carlos Caldas , Robert K Semple , Bart Vanhaesebroeck

WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity.

Science (New York, N.Y.)

Avec: Ming Liu , Jinyi Zhang , Benjamin D Pinder , Qingquan Liu , Dingyan Wang , Hao Yao , Yubo Gao , Aras Toker , Jimin Gao , Alan Peterson , Jia Qu , Katherine A Siminovitch

Superior Vena Cava Reconstruction in Masaoka Stage III and IVa Thymic Epithelial Tumors.

The Annals of thoracic surgery

Avec: Alper Toker , J W Awori Hayanga , Ankit Dhamija , Erkan Kaba , Berker Ozkan , Kemal Ayalp , Berk Cimenoglu , Ghulam Abbas

Omicron BA.2 breakthrough infection enhances cross-neutralization of BA.2.12.1 and BA.4/BA.5.

Science immunology

Avec: Alexander Muik , Bonny Gaby Lui , Maren Bacher , Ann-Kathrin Wallisch , Aras Toker , Andrew Finlayson , Kimberly Krüger , Orkun Ozhelvaci , Katharina Grikscheit , Sebastian Hoehl , Sandra Ciesek , Özlem Türeci , Ugur Sahin

Does Fissureless Videothoracoscopic Lobectomy Help for Postoperative Air Leak?

The Thoracic and cardiovascular surgeon

Avec: Murat Kara , Berker Özkan , Salih Duman , Eren Erdoğdu , Arda Sarıgül , Alper Toker

Réseau de co-auteurs

Alper Toker 10 collaborations

Aras Toker 6 collaborations

Renee C Geck 4 collaborations

Alexander Muik 4 collaborations

Özlem Türeci 4 collaborations

Ugur Sahin 4 collaborations

Erkan Kaba 3 collaborations

Kemal Ayalp 3 collaborations

J W Awori Hayanga 3 collaborations

Bonny Gaby Lui 3 collaborations

Maren Bacher 3 collaborations

Orkun Ozhelvaci 3 collaborations

Katharina Grikscheit 3 collaborations

Sandra Ciesek 3 collaborations

Aysun Toker 2 collaborations

John M Asara 2 collaborations

Berk Cimenoglu 2 collaborations

Berker Ozkan 2 collaborations

Jahnavi Kakuturu 2 collaborations

Ann-Kathrin Wallisch 2 collaborations

Jessica Grosser 2 collaborations

Andrew Finlayson 2 collaborations

Kimberly Krüger 2 collaborations

Niko Kohmer 2 collaborations

Sebastian Hoehl 2 collaborations

Ghulam Abbas 2 collaborations

Eren Erdoğdu 2 collaborations

Emily C Erickson 2 collaborations

Ankit Dhamija 2 collaborations

Ali U Uslu 1 collaboration

Adem Kucuk 1 collaboration

Sevket Balta 1 collaboration

Cengiz Ozturk 1 collaboration

Sevket Arslan 1 collaboration

Levent Tekin 1 collaboration

Sami Kucuksen 1 collaboration

Mehmet Kayrak 1 collaboration

Jianping Guo 1 collaboration

Xiangpeng Dai 1 collaboration

Benoit Laurent 1 collaboration

Nana Zheng 1 collaboration

Wenjian Gan 1 collaboration

Jian Zhang 1 collaboration

Ailan Guo 1 collaboration

Min Yuan 1 collaboration

Pengda Liu 1 collaboration

Yang Shi 1 collaboration

Pier Paolo Pandolfi 1 collaboration

Wenyi Wei 1 collaboration

Murat Basaran 1 collaboration

Hui Liu 1 collaboration

Marcia N Paddock 1 collaboration

Haibin Wang 1 collaboration

Charles J Murphy 1 collaboration

Adrija J Navarro 1 collaboration

Gerburg M Wulf 1 collaboration

Olivier Elemento 1 collaboration

Volker Haucke 1 collaboration

Lewis C Cantley 1 collaboration

Jackson R Foley 1 collaboration

Tracy Murray Stewart 1 collaboration

Robert A Casero 1 collaboration

Irfan Demir 1 collaboration

Hulya Aksoy 1 collaboration

Erkan Tasyurek 1 collaboration

Selcuk Zengin 1 collaboration

Tuğba Coşgun 1 collaboration

Isil Altintas 1 collaboration

Friederike Gieseke 1 collaboration

Kristina B Schoedel 1 collaboration

Saskia M Burm 1 collaboration

Theodora W Salcedo 1 collaboration

Dennis Verzijl 1 collaboration

David Eisel 1 collaboration

Christian Grunwitz 1 collaboration

Lena M Kranz 1 collaboration

Mathias Vormehr 1 collaboration

David P E Satijn 1 collaboration

Mustafa Diken 1 collaboration

Sebastian Kreiter 1 collaboration

Kate Sasser 1 collaboration

Tahamtan Ahmadi 1 collaboration

Esther C W Breij 1 collaboration

Maria Jure-Kunkel 1 collaboration

Jiaxi He 1 collaboration

Yunpeng Zhong 1 collaboration

Hon-Chi Suen 1 collaboration

Aditya Sengupta 1 collaboration

Raghav A Murthy 1 collaboration

Eirch Stoelben 1 collaboration

Angelo Carretta 1 collaboration

Chudong Wang 1 collaboration

Jianxing He 1 collaboration

Shuben Li 1 collaboration

Fatima Asad 1 collaboration

Anthony Siler 1 collaboration

Heather Hayanga 1 collaboration

Vinay Badhwar 1 collaboration

Carla Iris Cadima Couto 1 collaboration

Alptekin Güler 1 collaboration

Veena Mampilli 1 collaboration

Geneva J Schmitt 1 collaboration

Jonathan Mottl 1 collaboration

Thomas Ziegenhals 1 collaboration

Stephanie Fesser 1 collaboration

Jonas Reinholz 1 collaboration

Florian Wernig 1 collaboration

Karla-Gerlinde Schraut 1 collaboration

Hossam Hefesha 1 collaboration

Hui Cai 1 collaboration

Qi Yang 1 collaboration

Kerstin C Walzer 1 collaboration

Stefan Strauss 1 collaboration

Kena A Swanson 1 collaboration

Annette B Vogel 1 collaboration

Laura E Stevens 1 collaboration

Guillermo Peluffo 1 collaboration

Xintao Qiu 1 collaboration

Daniel Temko 1 collaboration

Anne Fassl 1 collaboration

Zheqi Li 1 collaboration

Anne Trinh 1 collaboration

Marco Seehawer 1 collaboration

Bojana Jovanović 1 collaboration

Maša Alečković 1 collaboration

Callahan M Wilde 1 collaboration

Shaokun Shu 1 collaboration

Natalie L Kingston 1 collaboration

Nicholas W Harper 1 collaboration

Vanessa Almendro 1 collaboration

Alanna L Pyke 1 collaboration

Shawn B Egri 1 collaboration

Malvina Papanastasiou 1 collaboration

Kendell Clement 1 collaboration

Ningxuan Zhou 1 collaboration

Sarah Walker 1 collaboration

Jacqueline Salas 1 collaboration

So Yeon Park 1 collaboration

David A Frank 1 collaboration

Alexander Meissner 1 collaboration

Jacob D Jaffe 1 collaboration

Piotr Sicinski 1 collaboration

Franziska Michor 1 collaboration

Henry W Long 1 collaboration

Beth A Overmoyer 1 collaboration

Kornelia Polyak 1 collaboration

Jasmin Quandt 1 collaboration

Huitian Diao 1 collaboration

Yunguan Fu 1 collaboration

Jessica Gordon 1 collaboration

Yaniv Lustig 1 collaboration

Gili Regev-Yochay 1 collaboration

Karim Beguir 1 collaboration

Asaf Poran 1 collaboration

Isabel Vogler 1 collaboration

Adam J Hansen 1 collaboration

Jeremiah Hayanga 1 collaboration

Percival Buenaventura 1 collaboration

Charlotte Spear 1 collaboration

Emily B Cohen 1 collaboration

Tugba Cosgun 1 collaboration

Erdoğan Dadaş 1 collaboration

Miray Ersöz 1 collaboration

Tamer Okay 1 collaboration

Heather L MacGregor 1 collaboration

Carlos Garcia-Batres 1 collaboration

Azin Sayad 1 collaboration

Andrew Elia 1 collaboration

Hal K Berman 1 collaboration

Sarah Rachel Katz 1 collaboration

Patricia A Shaw 1 collaboration

Blaise A Clarke 1 collaboration

Sarah Q Crome 1 collaboration

Celine Robert-Tissot 1 collaboration

Marcus Q Bernardini 1 collaboration

Linh T Nguyen 1 collaboration

Pamela S Ohashi 1 collaboration

Ralitsa R Madsen 1 collaboration

Oscar M Rueda 1 collaboration

Xavier Robin 1 collaboration

Carlos Caldas 1 collaboration

Robert K Semple 1 collaboration

Bart Vanhaesebroeck 1 collaboration

Ming Liu 1 collaboration

Jinyi Zhang 1 collaboration

Benjamin D Pinder 1 collaboration

Qingquan Liu 1 collaboration

Dingyan Wang 1 collaboration

Hao Yao 1 collaboration

Yubo Gao 1 collaboration

Jimin Gao 1 collaboration

Alan Peterson 1 collaboration

Jia Qu 1 collaboration

Katherine A Siminovitch 1 collaboration

Murat Kara 1 collaboration

Berker Özkan 1 collaboration

Salih Duman 1 collaboration

Arda Sarıgül 1 collaboration