Two weeks of exercise alters neuronal extracellular vesicle insulin signaling proteins and pro-BDNF in older adults with prediabetes.
aging
glucose tolerance
insulin sensitivity
obesity
physical activity
type 2 diabetes
Journal
Aging cell
ISSN: 1474-9726
Titre abrégé: Aging Cell
Pays: England
ID NLM: 101130839
Informations de publication
Date de publication:
18 Oct 2024
18 Oct 2024
Historique:
revised:
29
08
2024
received:
01
05
2024
accepted:
17
09
2024
medline:
18
10
2024
pubmed:
18
10
2024
entrez:
18
10
2024
Statut:
aheadofprint
Résumé
Adults with prediabetes are at risk for Alzheimer's Disease and Related Dementia (ADRD). While exercise may lower ADRD risk, the exact mechanism is unclear. We tested the hypothesis that short-term exercise would raise neuronal insulin signaling and pro-BDNF in neuronal extracellular vesicles (nEVs) in prediabetes. Twenty-one older adults (18F, 60.0 ± 8.6 yrs.; BMI: 33.5 ± 1.1 kg/m
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e14369Subventions
Organisme : National Heart and Lung Institute
ID : RO1-HL130296
Informations de copyright
© 2024 The Author(s). Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.
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