Tumoricidal Activity and Side Effects of Radiolabeled Anti-NCAM [

Animals Neuroblastoma / pathology Mice Iodine Radioisotopes / adverse effects Cell Line, Tumor Neural Cell Adhesion Molecules / metabolism Humans Mice, SCID Xenograft Model Antitumor Assays Immunoconjugates / pharmacology Female Antibodies, Monoclonal / therapeutic use
antibodies neuroblastoma radioimmunotherapy targeted radiotherapy theranostics

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
05 Oct 2024
Historique:
received: 20 08 2024
revised: 23 09 2024
accepted: 01 10 2024
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

Preliminary studies on a radioactive antibody against the neural cell adhesion molecule (NCAM) demonstrated a significant accumulation of [

Identifiants

DOI: 10.3390/ijms251910737 PMID: 39409066
pubmed: 39409066
pii: ijms251910737
doi: 10.3390/ijms251910737
pii:
doi:

Substances chimiques

Iodine Radioisotopes 0
Neural Cell Adhesion Molecules 0
Immunoconjugates 0
Iodine-131 0
Antibodies, Monoclonal 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Thomas Fischer (T)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
ORCID: 0000-0001-6118-5182

Felix Dietlein (F)

Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
ORCID: 0000-0002-6651-7155

Detlev Bongartz (D)

Department of Pediatric Oncology and Hematology, Center for Integrated Oncology, University of Cologne, 50937 Cologne, Germany.

Martin Klehr (M)

Department of Pain Management, Helios Hospital, 47805 Krefeld, Germany.

Beate Zimmermanns (B)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
ORCID: 0009-0009-2207-9657

Matthias Schmidt (M)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
ORCID: 0000-0002-7519-8897

Angela Mohr (A)

School of Mathematics and Science, Inorganic Chemistry, University Wuppertal, 42119 Wuppertal, Germany.

Fabian Mohr (F)

School of Mathematics and Science, Inorganic Chemistry, University Wuppertal, 42119 Wuppertal, Germany.
ORCID: 0000-0001-7272-935X

Ferdinand Sudbrock (F)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.

Philipp Krapf (P)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Straße, 52428 Jülich, Germany.

Alexander Drzezga (A)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Straße, 52428 Jülich, Germany.
German Center for Neurodegenerative Diseases (DZNE), Bonn-Cologne, Venusberg-Campus 1/99, 53127 Bonn, Germany.

Markus Dietlein (M)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
ORCID: 0000-0003-0992-6099

Klaus Schomäcker (K)

Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.

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Classifications MeSH

Recherchemedicale.com › Eucaryotes › Animaux › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Tumeurs neuroectodermiques primitives › Tumeurs neuroectodermiques primitives périphériques › Neuroblastome › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Produits chimiques inorganiques › Isotopes › Radio-isotopes › Radio-isotopes de l'iode › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Molécules d'adhérence cellulaire neuronale › Molécules d'adhérence cellulaire neurales › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris SCID › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Techniques d'investigation › Transplantation tumorale › Tests d'activité antitumorale sur modèle de xénogreffe › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunoconjugués › Tumoricidal Activity and Side Effects of...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Tumoricidal Activity and Side Effects of...