Evaluation of Knowledge, Attitudes and Practices for Hepatitis B Virus Infection Among Primary Healthcare Physicians in Georgia.
Georgia
KAP
hepatitis B
primary healthcare workers
viral hepatitis
Journal
Journal of viral hepatitis
ISSN: 1365-2893
Titre abrégé: J Viral Hepat
Pays: England
ID NLM: 9435672
Informations de publication
Date de publication:
10 Oct 2024
10 Oct 2024
Historique:
revised:
05
08
2024
received:
24
04
2024
accepted:
20
09
2024
medline:
13
10
2024
pubmed:
13
10
2024
entrez:
10
10
2024
Statut:
aheadofprint
Résumé
A nationwide serosurvey among adults in 2021 showed a 2.7% (95% confidence interval [CI]: 2.3%-3.4%) prevalence of hepatitis B. Our analysis evaluates knowledge, attitudes and practices (KAP) for hepatitis B virus (HBV) infection among primary healthcare physicians (PHPs) in Georgia. We randomly selected 550 PHPs from medical facilities in Georgia's six largest cities. Using bivariate ordinal regression, we assessed the association of socio-demographic factors with an ordinal knowledge score (low/middle/high). Multivariable logistic regression was performed to calculate adjusted odds ratios (aOR) and 95% CI to determine associations between HBV knowledge score and practices. Of 550 selected PHPs, 506 (92.0%) agreed to participate. Among them, 62.8% scored in the medium or high knowledge tertiles, 72.7% were confident in diagnosing HBV infection, 37.3% were confident in managing patients with hepatitis B; 47.4% reported being screened for and 26.2% reported being vaccinated against HBV infection. Compared to those with low knowledge scores, PHPs with a high score were less likely to recommend activities not supported by evidence, such as: the use of 'hepatoprotective' medications (aOR 0.43, 95% CI 0.25-0.73), caesarean sections (aOR 0.47, 95% CI 0.27-0.82) and withholding breastfeeding (aOR 0.57, 95% CI 0.34-0.96) to prevent HBV transmission. The majority of PHPs were confident in diagnosing HBV infection, but only one in three were confident in managing patients with hepatitis B. PHPs with higher HBV knowledge were less likely to provide inaccurate instructions to their patients. These findings will help to develop awareness and education campaigns supporting HBV elimination in Georgia.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Cooperative agreement between Centers for Disease Control and Prevention, Global Immunization Division and Integral Global Health
ID : #GH21-2102
Informations de copyright
© 2024 The Author(s). Journal of Viral Hepatitis published by John Wiley & Sons Ltd.
Références
Accountability for the Global Health Sector Strategies 2016–2021: Actions for Impact, Global Progress Report on HIV, Viral Hepatitis and Sexually Transmitted Infections (Geneva: World Health Organization, 2021).
World Health Organization, Global Health Sector Strategy on Viral Hepatitis 2016–2021. towards Ending Viral Hepatitis (World Health Organization, 2016), https://www.who.int/publications‐detail‐redirect/who‐hiv‐2016.06.
A. Kasradze, S. Shadaker, T. Kuchuloria, et al., “The Burden and Epidemiology of Hepatitis B and Hepatitis D in Georgia: Findings From the National Seroprevalence Survey,” Public Health 185 (2020): 341–347, https://doi.org/10.1016/j.puhe.2020.06.024.
Centers for Disease Control and Prevention, “Georgia Hepatitis Elimination Program Progress Report 2020–2021,” (2021), https://stacks.cdc.gov/view/cdc/123936.
N. G. Khetsuriani, A. Shadaker, S. Tsereteli, et al., “Toward Reaching Hepatitis B Goals: Hepatitis B Epidemiology and the Impact of Two Decades of Vaccination, Georgia, 2021,” Eurosurveillance 28 (2023): 2200837, https://doi.org/10.2807/1560‐7917.ES.2023.28.30.2200837.
E. M. Bloch, E. Kipiani, S. Shadaker, et al., “Blood Transfusion Safety in the Country of Georgia: Collateral Benefit From a National Hepatitis C Elimination Program,” Transfusion 60, no. 6 (2020): 1243–1252, https://doi.org/10.1111/trf.15815.
T. Abzianidze, M. Butsashvili, M. Kajaia, et al., “Hepatitis B Vaccination: Knowledge and Attitude Among Women of Reproductive Age in Georgia,” Georgian Medical News 295 (2019): 109–114.
M. Kochlamazashvili, G. Kamkamidze, L.‐A. McNutt, J. DeHovitz, O. Chubinishvili, and M. Butsashvili, “Knowledge, Attitudes and Practice Survey on Blood‐Borne Diseases Among Dental Health Care Workers in Georgia,” Journal of Infection in Developing Countries 12, no. 10 (2018): 864–870, https://doi.org/10.3855/Jidc.9911.
C. Boni, P. Fisicaro, C. Valdatta, et al., “Characterization of Hepatitis B Virus (Hbv)‐Specific T‐Cell Dysfunction in Chronic HBV Infection,” Journal of Virology 81, no. 8 (2007): 4215–4225, https://doi.org/10.1128/jvi.02844‐06.
Y. Zhou, J. Wang, D. Zhang, et al., “Mechanism of Drug‐Induced Liver Injury and Hepatoprotective Effects of Natural Drugs,” Chinese Medicine 16 (2021): 135, https://doi.org/10.1186/s13020‐021‐00543‐x.
M. Li, Q. Luo, Y. Tao, X. Sun, and C. Liu, “Pharmacotherapies for Drug‐Induced Liver Injury: A Current Literature Review,” Frontiers in Pharmacology 12 (2022): 806249, https://doi.org/10.3389/fphar.2021.806249.
National Center for Complementary and Integrative Health, Milk Thistle, accessed October 3, 2023, https://www.nccih.nih.gov/health/milk‐thistle.
H. Farghali, N. K. Canová, and S. Zakhari, “Hepatoprotective Properties of Extensively Studied Medicinal Plant Active Constituents: Possible Common Mechanisms,” Pharmaceutical Biology 53, no. 6 (2014): 781–791, https://doi.org/10.3109/13880209.2014.950387.
M. Topuridze, M. Butsashvili, G. Kamkamidze, M. Kajaia, D. Morse, and L. A. McNutt, “Barriers to Hepatitis B Vaccine Coverage Among Healthcare Workers in the Republic of Georgia: An International Perspective,” Infection Control and Hospital Epidemiology 31, no. 2 (2010): 158–164, https://doi.org/10.1086/649795.
A. H. Al‐Hazmi, “Knowledge, Attitudes and Practice of Primary Health Care Physicians Towards Hepatitis B Virus in Al‐Jouf Province, Saudi Arabia,” BMC Research Notes 7, no. 1 (2014): 288, https://doi.org/10.1186/1756‐0500‐7‐288.
T. Ssekamatte, J. B. Isunju, P. A. Zirimala, et al., “A Positive Attitude Among Primary Healthcare Providers Predicts Better Hepatitis B Prevention Practices: Evidence From a Cross‐Sectional Survey in Wakiso District, Central Uganda,” Health Psychology and Behavioral Medicine 9, no. 1 (2021): 298–314, https://doi.org/10.1080/21642850.2021.1904935.
A. Ali, S. Khan, S. Malik, M. Haris Iqbal, and M. Aadil, “Comparison of Knowledge and Attitudes Regarding Hepatitis B Among Healthcare Professionals in Pakistan,” Cureus 9 (2017): e1049, https://doi.org/10.7759/cureus.1049.
M. A. Khan, M. F. Khilji, A. R. Janjua, M. Imran, and K. H. Altintas, “Hepatitis B and C Related Knowledge, Attitudes and Practices of Health Care Workers in Azad Kashmir, Pakistan—A Potentially Disastrous Area,” International Journal of Endorsing Health Science Research 7, no. 1 (2019): 39–46, https://doi.org/10.29052/ijehsr.v7.i1.2019.39‐46.
M. SM‐elbager and S. O. Mohamed, “Knowledge, Attitude, and Practice Towards Hepatitis B Infection Among Nurses and Midwives in Two Maternity Hospitals in Khartoum, Sudan,” BMC Public Health 19, no. 1 (2019): 1597, https://doi.org/10.1186/s12889‐019‐7982‐8.
A. A. Moussa, A. A. Abdi, and S. A. Abdullahi, “Assessment of Knowledge, Attitude and Practice of Healthcare Workers Towards Hepatitis B Virus Infection in Mogadishu, Somalia: A Cross‐Sectional Study,” (2020), https://doi.org/10.21203/rs.2.23628/v1.
N. Naranzul, B. Burmaajav, A. Enkhjargal, et al., “Knowledge, Attitudes, and Practices (KAP) Regarding Hepatitis B Vaccination Among Healthcare Workers in Mongolia,” Occupational Diseases and Environmental Medicine 11, no. 1 (2023): 30–48, https://doi.org/10.4236/odem.2023.111002.
T. T. Hang Pham, T. X. Le, D. T. Nguyen, et al., “Knowledge, Attitudes and Medical Practice Regarding Hepatitis B Prevention and Management Among Healthcare Workers in Northern Vietnam,” PLoS One 14, no. 10 (2019): 223733, https://doi.org/10.1371/journal.pone.0223733.
M. Dvalishvili, D. Mesxishvili, M. Butsashvili, G. Kamkamidze, D. McFarland, and R. A. Bednarczyk, “Knowledge, Attitudes, and Practices of Healthcare Providers in the Country of Georgia Regarding Influenza Vaccinations for Pregnant Women,” Vaccine 34, no. 48 (2016): 5907–5911.