[18F]DOPA PET for lesion definition and contouring using different thresholds in patients with gliomas.


Journal

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...
ISSN: 1827-1936
Titre abrégé: Q J Nucl Med Mol Imaging
Pays: Italy
ID NLM: 101213861

Informations de publication

Date de publication:
23 Sep 2024
Historique:
medline: 23 9 2024
pubmed: 23 9 2024
entrez: 23 9 2024
Statut: aheadofprint

Résumé

Amino-acid (AA) PET has recently been endorsed by the ESTRO-EANO guidelines for RT-planning in glioblastomas, with recommended lesion-to-brain-ratio thresholds (1.6-1.8) derived from a biopsy-controlled FET-PET study. We aimed to compare target definition at [ A retrospective analysis was conducted on glioma patients scanned with [ 50 patients were included (36 previously received surgery). Volume definition based on the striatum SUV<inf>max</inf> was significantly smaller compared to other thresholds (2.1 cm The ESTRO-EANO FET-PET thresholds proved to be interchangeable in patients scanned with [

Sections du résumé

BACKGROUND BACKGROUND
Amino-acid (AA) PET has recently been endorsed by the ESTRO-EANO guidelines for RT-planning in glioblastomas, with recommended lesion-to-brain-ratio thresholds (1.6-1.8) derived from a biopsy-controlled FET-PET study. We aimed to compare target definition at [
METHODS METHODS
A retrospective analysis was conducted on glioma patients scanned with [
RESULTS RESULTS
50 patients were included (36 previously received surgery). Volume definition based on the striatum SUV<inf>max</inf> was significantly smaller compared to other thresholds (2.1 cm
CONCLUSIONS CONCLUSIONS
The ESTRO-EANO FET-PET thresholds proved to be interchangeable in patients scanned with [

Identifiants

pubmed: 39311479
pii: S1824-4785.24.03587-8
doi: 10.23736/S1824-4785.24.03587-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Gloria Garelli (G)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Medical Sciences, University of Turin, Turin, Italy.

Guido Rovera (G)

Department of Medical Sciences, University of Turin, Turin, Italy.

Mario Levis (M)

Department of Oncology, University of Turin, Turin, Italy.

Adriana Lesca (A)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Medical Sciences, University of Turin, Turin, Italy.

Alessia Pellerino (A)

Division of Neuro-Oncology, &quot;Rita Levi Montalcini&quot; Department of Neuroscience, AOU Città della Salute e della Scienza, Turin, Italy.

Francesco Bruno (F)

Division of Neuro-Oncology, &quot;Rita Levi Montalcini&quot; Department of Neuroscience, AOU Città della Salute e della Scienza, Turin, Italy.

Alessandra Agosti (A)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Medical Sciences, University of Turin, Turin, Italy.

Maria L Mangia (ML)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Medical Sciences, University of Turin, Turin, Italy.

Martina Cioffi (M)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Medical Sciences, University of Turin, Turin, Italy.

Alessandro Coccarelli (A)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Medical Sciences, University of Turin, Turin, Italy.

Giovanni Morana (G)

Neuroradiology Unit, AOU Città della Salute e della Scienza, Turin, Italy.
Department of Neurosciences, University of Turin, Turin, Italy.

Umberto Ricardi (U)

Department of Oncology, University of Turin, Turin, Italy.

Roberta Rudà (R)

Division of Neuro-Oncology, &quot;Rita Levi Montalcini&quot; Department of Neuroscience, AOU Città della Salute e della Scienza, Turin, Italy.

Silvia Morbelli (S)

IRCCS San Martino Polyclinic Hospital, Genoa, Italy.

Michela Zotta (M)

Nuclear Medicine Unit, Department of Medical Sciences, AOU Città della Salute e della Scienza, Turin, Italy - michela.zotta@unito.it.
Department of Medical Sciences, University of Turin, Turin, Italy.

Classifications MeSH