Exploring the therapeutic potential of topical probiotics in dermatological diseases: a comprehensive review of clinical studies.

Acne Lactobacillus bacterium dermatitis local efficacy probiotic skin topical treatment

Journal

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
ISSN: 1610-0387
Titre abrégé: J Dtsch Dermatol Ges
Pays: Germany
ID NLM: 101164708

Informations de publication

Date de publication:
20 Aug 2024
Historique:
received: 05 12 2023
accepted: 23 04 2024
medline: 21 8 2024
pubmed: 21 8 2024
entrez: 21 8 2024
Statut: aheadofprint

Résumé

The gastrointestinal tract may contribute to the regulation of systemic inflammation and skin diseases due to the balance between the pathogenic, opportunistic, and beneficial bacterial species it contains. External supplementation of beneficial bacteria, besides its known positive effect in the treatment of digestive system diseases, also has different favorable effects such as accelerated wound healing, suppression of inflammation, lower infection risk, and reduced antibiotic requirement. It has been reported that oral use of probiotics may be effective in the treatment of skin diseases such as acne, psoriasis, and atopic dermatitis. Furthermore, topical administration of probiotics may create a positive bacterial balance, eliminate pathological conditions, and thus have a favorable impact on the management of skin diseases. Interest in the effect of the skin microbiome and topical probiotics in the treatment of skin diseases has increased recently. Herein, 21 clinical studies and a case report in the PubMed database on the use of topical probiotics in dermatological diseases were evaluated.

Identifiants

pubmed: 39164814
doi: 10.1111/ddg.15465
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 Deutsche Dermatologische Gesellschaft (DDG).

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Auteurs

Funda Tamer (F)

Department of Dermatology, Gazi University School of Medicine, Ankara, Turkey.

Murat Kekilli (M)

Department of Gastroenterology, Gazi University School of Medicine, Department of Gastroenterology, Ankara, Turkey.

Classifications MeSH