Fine-scale maps of malaria incidence to inform risk stratification in Laos.


Journal

Malaria journal
ISSN: 1475-2875
Titre abrégé: Malar J
Pays: England
ID NLM: 101139802

Informations de publication

Date de publication:
25 Jun 2024
Historique:
received: 23 01 2024
accepted: 01 06 2024
medline: 26 6 2024
pubmed: 26 6 2024
entrez: 25 6 2024
Statut: epublish

Résumé

Malaria risk maps are crucial for controlling and eliminating malaria by identifying areas of varying transmission risk. In the Greater Mekong Subregion, these maps guide interventions and resource allocation. This article focuses on analysing changes in malaria transmission and developing fine-scale risk maps using five years of routine surveillance data in Laos (2017-2021). The study employed data from 1160 geolocated health facilities in Laos, along with high-resolution environmental data. A Bayesian geostatistical framework incorporating population data and treatment-seeking propensity was developed. The models incorporated static and dynamic factors and accounted for spatial heterogeneity. Results showed a significant decline in malaria cases in Laos over the five-year period and a shift in transmission patterns. While the north became malaria-free, the south experienced ongoing transmission with sporadic outbreaks. The risk maps provided insights into changing transmission patterns and supported risk stratification. These risk maps are valuable tools for malaria control in Laos, aiding resource allocation, identifying intervention gaps, and raising public awareness. The study enhances understanding of malaria transmission dynamics and facilitates evidence-based decision-making for targeted interventions in high-risk areas.

Sections du résumé

BACKGROUND BACKGROUND
Malaria risk maps are crucial for controlling and eliminating malaria by identifying areas of varying transmission risk. In the Greater Mekong Subregion, these maps guide interventions and resource allocation. This article focuses on analysing changes in malaria transmission and developing fine-scale risk maps using five years of routine surveillance data in Laos (2017-2021). The study employed data from 1160 geolocated health facilities in Laos, along with high-resolution environmental data.
METHODS METHODS
A Bayesian geostatistical framework incorporating population data and treatment-seeking propensity was developed. The models incorporated static and dynamic factors and accounted for spatial heterogeneity.
RESULTS RESULTS
Results showed a significant decline in malaria cases in Laos over the five-year period and a shift in transmission patterns. While the north became malaria-free, the south experienced ongoing transmission with sporadic outbreaks.
CONCLUSION CONCLUSIONS
The risk maps provided insights into changing transmission patterns and supported risk stratification. These risk maps are valuable tools for malaria control in Laos, aiding resource allocation, identifying intervention gaps, and raising public awareness. The study enhances understanding of malaria transmission dynamics and facilitates evidence-based decision-making for targeted interventions in high-risk areas.

Identifiants

pubmed: 38918779
doi: 10.1186/s12936-024-05007-9
pii: 10.1186/s12936-024-05007-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

196

Subventions

Organisme : Clinton Health Access Initiative
ID : BMGFMELIM4

Informations de copyright

© 2024. The Author(s).

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Auteurs

Su Yun Kang (SY)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia. Su.Kang@telethonkids.org.au.

Punam Amratia (P)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia. Punam.Amratia@telethonkids.org.au.
Ifakara Health Institute, Dar es Salaam, Tanzania. Punam.Amratia@telethonkids.org.au.

Julia Dunn (J)

Clinton Health Access Initiative, Boston, USA.

Phoutnalong Vilay (P)

Centre of Malariology, Parasitology and Entomology, Vientiane, Lao PDR.

Mark Connell (M)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.

Tasmin Symons (T)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.
Curtin University, Perth, Australia.

Susan Rumisha (S)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.
Ifakara Health Institute, Dar es Salaam, Tanzania.

Song Zhang (S)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.

Abigail Ward (A)

Clinton Health Access Initiative, Boston, USA.

Odai Sichanthongthip (O)

Centre of Malariology, Parasitology and Entomology, Vientiane, Lao PDR.

Virasack Banouvong (V)

Centre of Malariology, Parasitology and Entomology, Vientiane, Lao PDR.

Mathew Shortus (M)

World Health Organization, Vientiane, Lao PDR.

Rita Reyburn (R)

World Health Organization, Vientiane, Lao PDR.

Phonephet Butphomvihane (P)

World Health Organization, Vientiane, Lao PDR.

Vilaisak Phiphakavong (V)

World Health Organization, Vientiane, Lao PDR.

Mary Hahm (M)

Clinton Health Access Initiative, Boston, USA.

Vilayphone Phongchantha (V)

Clinton Health Access Initiative, Boston, USA.

Boualam Khamlome (B)

Centre of Malariology, Parasitology and Entomology, Vientiane, Lao PDR.

Keobouphaphone Chindavongsa (K)

Centre of Malariology, Parasitology and Entomology, Vientiane, Lao PDR.

Chitsavang Chanthavisouk (C)

World Health Organization, Vientiane, Lao PDR.

Daniel J Weiss (DJ)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.
Curtin University, Perth, Australia.

Peter W Gething (PW)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.
Curtin University, Perth, Australia.

Ewan Cameron (E)

Telethon Kids Institute, Perth Children's Hospital, Perth, Australia.
Curtin University, Perth, Australia.

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