Genetic barrier to resistance: a critical parameter for efficacy of neutralizing monoclonal antibodies against SARS-CoV-2 in a nonhuman primate model.

SARS-CoV-2 antibody therapy barrier to resistance neutralizing monoclonal antibodies nonhuman primate model

Journal

Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724

Informations de publication

Date de publication:
20 Jun 2024
Historique:
medline: 20 6 2024
pubmed: 20 6 2024
entrez: 20 6 2024
Statut: aheadofprint

Résumé

The potency of antibody neutralization in cell culture has been used as the key criterion for selection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for clinical development. As other aspects may also influence the degree of protection

Identifiants

DOI: 10.1128/jvi.00628-24 PMID: 38899895
pubmed: 38899895
doi: 10.1128/jvi.00628-24
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0062824

Auteurs

Christiane Stahl-Hennig (C)

Unit of Infection Models, German Primate Center, Göttingen, Germany.

Antonia Sophia Peter (AS)

Institute of Clinical and Molecular Virology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
ORCID: 0000-0001-9667-2247

Arne Cordsmeier (A)

Institute of Clinical and Molecular Virology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Nicole Stolte-Leeb (N)

Unit of Infection Models, German Primate Center, Göttingen, Germany.

Ramona Vestweber (R)

Unit of Infection Models, German Primate Center, Göttingen, Germany.

Eileen Socher (E)

Institute of Anatomy, Functional and Clinical Anatomy, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Samuel Alberto Merida (SA)

Unit of Infection Models, German Primate Center, Göttingen, Germany.

Ulrike Sauermann (U)

Unit of Infection Models, German Primate Center, Göttingen, Germany.

Martina Bleyer (M)

Unit of Infection Models, German Primate Center, Göttingen, Germany.

Kirsten Fraedrich (K)

Institute of Clinical and Molecular Virology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Thomas Grunwald (T)

Department of Vaccines and Infection Models, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.

Thomas H Winkler (TH)

Division of Genetics, Department Biology, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Armin Ensser (A)

Institute of Clinical and Molecular Virology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
ORCID: 0000-0001-8873-3863

Hans-Martin Jäck (H-M)

Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Klaus Überla (K)

Institute of Clinical and Molecular Virology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
ORCID: 0000-0001-7822-3835

Classifications MeSH