ALK Inhibition With Alectinib for Refractory Metastatic Renal Cell Carcinoma With ALK Rearrangement: A Rare Case Report and Literature Review.

Humans Anaplastic Lymphoma Kinase / genetics Piperidines / therapeutic use Carbazoles / therapeutic use Carcinoma, Renal Cell / drug therapy Kidney Neoplasms / drug therapy Gene Rearrangement Protein Kinase Inhibitors / therapeutic use Male Middle Aged Female

Journal

JCO precision oncology
ISSN: 2473-4284
Titre abrégé: JCO Precis Oncol
Pays: United States
ID NLM: 101705370

Informations de publication

Date de publication:
Jun 2024
Historique:
medline: 17 6 2024
pubmed: 17 6 2024
entrez: 17 6 2024
Statut: ppublish

Résumé

ALK-rearranged RCC refractory to several lines of treatment has a durable response when treated with alectinib.

Identifiants

DOI: 10.1200/PO.24.00154 PMID: 38885453
pubmed: 38885453
doi: 10.1200/PO.24.00154
doi:

Substances chimiques

alectinib LIJ4CT1Z3Y
Anaplastic Lymphoma Kinase EC 2.7.10.1
Piperidines 0
Carbazoles 0
ALK protein, human EC 2.7.10.1
Protein Kinase Inhibitors 0

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2400154

Auteurs

Nikhita Kathuria-Prakash (N)

Division of Hematology/Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA.
ORCID: 0000-0002-0370-5650

Lidia P Lopez (LP)

Division of Hematology/Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA.

Steven Raman (S)

Department of Radiology, University of California, Los Angeles, Los Angeles, CA.

Huihui Ye (H)

Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA.

Jordan Anaokar (J)

Department of Radiology, University of California, Los Angeles, Los Angeles, CA.

Anthony Sisk (A)

Department of Pathology, University of California, Los Angeles, Los Angeles, CA.

Allan J Pantuck (AJ)

Department of Urology, University of California, Los Angeles, Los Angeles, CA.

Alexandra Drakaki (A)

Division of Hematology/Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA.
ORCID: 0000-0001-8865-3548

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Classifications MeSH

Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs à activité tyrosine kinase › Kinase du lymphome anaplasique › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Composés hétérocycliques › Composés hétéromonocycliques › Pipéridines › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérocycliques 3 noyaux › Carbazoles › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Maladies urogénitales › Maladies urologiques › Tumeurs urologiques › Tumeurs du rein › Néphrocarcinome › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Maladies urogénitales › Maladies urologiques › Tumeurs urologiques › Tumeurs du rein › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Phénomènes génétiques › Réarrangement des gènes › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéines kinases › ALK Inhibition With Alectinib for Refractory...
Recherchemedicale.com › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › ALK Inhibition With Alectinib for Refractory...