Ventilatory efficiency in long-term dyspnoeic patients following COVID-19 pneumonia.
Journal
Respiratory physiology & neurobiology
ISSN: 1878-1519
Titre abrégé: Respir Physiol Neurobiol
Pays: Netherlands
ID NLM: 101140022
Informations de publication
Date de publication:
31 May 2024
31 May 2024
Historique:
received:
11
04
2024
revised:
20
05
2024
accepted:
29
05
2024
medline:
3
6
2024
pubmed:
3
6
2024
entrez:
2
6
2024
Statut:
aheadofprint
Résumé
Long COVID is defined as persistency of symptoms, such as exertional dyspnea, twelve weeks after recovery from SARS-CoV-2 infection. To investigate ventilatory efficiency by the use of cardiopulmonary exercise testing (CPET) in patients with exertional dyspnea despite normal basal spirometry after 18 (T One hundred patients with moderate-critical COVID-19 were prospectively enrolled in our Long COVID program. Medical history, physical examination and lung high-resolution computed tomography (HRCT) were obtained at hospitalization (T Remarkably, at CPET, ventilatory efficiency was reduced both at T At eighteen months from COVID-19 pneumonia, 20% of subjects still complains of exertional dyspnea. At CPET this may be explained by persistently reduced ventilatory efficiency, possibly related to the degree of lung parenchymal involvement in the acute phase of infection, likely reflecting a damage in the pulmonary circulation.
Sections du résumé
BACKGROUND
BACKGROUND
Long COVID is defined as persistency of symptoms, such as exertional dyspnea, twelve weeks after recovery from SARS-CoV-2 infection.
OBJECTIVES
OBJECTIVE
To investigate ventilatory efficiency by the use of cardiopulmonary exercise testing (CPET) in patients with exertional dyspnea despite normal basal spirometry after 18 (T
METHODS
METHODS
One hundred patients with moderate-critical COVID-19 were prospectively enrolled in our Long COVID program. Medical history, physical examination and lung high-resolution computed tomography (HRCT) were obtained at hospitalization (T
RESULTS
RESULTS
Remarkably, at CPET, ventilatory efficiency was reduced both at T
CONCLUSIONS
CONCLUSIONS
At eighteen months from COVID-19 pneumonia, 20% of subjects still complains of exertional dyspnea. At CPET this may be explained by persistently reduced ventilatory efficiency, possibly related to the degree of lung parenchymal involvement in the acute phase of infection, likely reflecting a damage in the pulmonary circulation.
Identifiants
pubmed: 38825094
pii: S1569-9048(24)00078-8
doi: 10.1016/j.resp.2024.104285
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104285Informations de copyright
Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.