The Detection of Influenza Virus Before and During the COVID-19 Pandemic in Cameroon.
COVID‐19 pandemic
Cameroon
SARS‐CoV‐2
epidemiology
influenza
Journal
Influenza and other respiratory viruses
ISSN: 1750-2659
Titre abrégé: Influenza Other Respir Viruses
Pays: England
ID NLM: 101304007
Informations de publication
Date de publication:
May 2024
May 2024
Historique:
revised:
22
04
2024
received:
20
09
2023
accepted:
23
04
2024
medline:
17
5
2024
pubmed:
17
5
2024
entrez:
17
5
2024
Statut:
ppublish
Résumé
Influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are both respiratory viruses with similar clinical manifestations and modes of transmission. This study describes influenza data before and during the coronavirus disease pandemic (COVID-19) in Cameroon and SARS-CoV-2 data during the pandemic period. The study ran from 2017 to 2022, and data were divided into two periods: before (2017-2019) and during (2020-2022) the COVID-19 pandemic. Nasopharyngeal samples collected from persons with respiratory illness were tested for influenza using the Centers for Disease Control and Prevention (CDC) typing and subtyping assays. During the COVID-19 pandemic, the respiratory specimens were simultaneously tested for SARS-CoV-2 using the DaAn gene protocol or the Abbott real-time SARS-CoV-2 assay. The WHO average curve method was used to compare influenza virus seasonality before and during the pandemic. A total of 6246 samples were tested. Influenza virus detection rates were significantly higher in the pre-pandemic period compared to the pandemic period (30.8% vs. 15.5%; p < 0.001). Meanwhile, the SARS-CoV-2 detection rate was 2.5%. A change in the seasonality of influenza viruses was observed from a bi-annual peak before the pandemic to no clear seasonal pattern during the pandemic. The age groups 2-4 and 5-14 years were significantly associated with higher influenza positivity rates in both pre-pandemic and pandemic periods. For SARS-CoV-2, all age groups above 15 years were the most affected population. The COVID-19 pandemic had a significant impact on the seasonal influenza by changing the seasonality of the virus and reducing its detection rates.
Sections du résumé
BACKGROUND
BACKGROUND
Influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are both respiratory viruses with similar clinical manifestations and modes of transmission. This study describes influenza data before and during the coronavirus disease pandemic (COVID-19) in Cameroon and SARS-CoV-2 data during the pandemic period.
METHODS
METHODS
The study ran from 2017 to 2022, and data were divided into two periods: before (2017-2019) and during (2020-2022) the COVID-19 pandemic. Nasopharyngeal samples collected from persons with respiratory illness were tested for influenza using the Centers for Disease Control and Prevention (CDC) typing and subtyping assays. During the COVID-19 pandemic, the respiratory specimens were simultaneously tested for SARS-CoV-2 using the DaAn gene protocol or the Abbott real-time SARS-CoV-2 assay. The WHO average curve method was used to compare influenza virus seasonality before and during the pandemic.
RESULTS
RESULTS
A total of 6246 samples were tested. Influenza virus detection rates were significantly higher in the pre-pandemic period compared to the pandemic period (30.8% vs. 15.5%; p < 0.001). Meanwhile, the SARS-CoV-2 detection rate was 2.5%. A change in the seasonality of influenza viruses was observed from a bi-annual peak before the pandemic to no clear seasonal pattern during the pandemic. The age groups 2-4 and 5-14 years were significantly associated with higher influenza positivity rates in both pre-pandemic and pandemic periods. For SARS-CoV-2, all age groups above 15 years were the most affected population.
CONCLUSION
CONCLUSIONS
The COVID-19 pandemic had a significant impact on the seasonal influenza by changing the seasonality of the virus and reducing its detection rates.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13313Subventions
Organisme : U.S. Department of Health and Human Services
ID : 6 DESP060001-01-01
Organisme : CDC HHS
Pays : United States
Informations de copyright
© 2024 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
Références
“Influenza (Seasonal),” accessed April 9, 2023, https://www.who.int/news‐room/fact‐sheets/detail/influenza‐(seasonal).
“Celebrating 70 Years of GISRS (the Global Influenza Surveillance and Response System),” accessed May 2, 2023, https://www.who.int/news/item/03‐02‐2022‐2022‐celebrating‐70‐years‐of‐gisrs‐(the‐global‐influenza‐surveillance‐and‐response‐system).
“Influenza & COVID19,” accessed May 2, 2023, https://www.who.int/teams/global‐influenza‐programme/influenza‐covid19.
“WHO Coronavirus (COVID‐19) Dashboard,” accessed May 5, 2023, https://covid19.who.int.
“Cameroon COVID‐19 Situation Report N°175,” CCOUSP, accessed May 2, 2023, https://www.ccousp.cm/download/rapport‐situation‐covid‐19‐cameroun‐n175/.
K. Yuki, M. Fujiogi, and S. Koutsogiannaki, “COVID‐19 Pathophysiology: A Review,” Clinical Immunology 215 (2020): 108427, https://doi.org/10.3174/ajnr.A8198.
Y. Alimohamadi, M. Sepandi, M. Taghdir, and H. Hosamirudsari, “Determine the Most Common Clinical Symptoms in COVID‐19 Patients: A Systematic Review and Meta‐Analysis,” Journal of Preventive Medicine and Hygiene 61, no. 3 (2020): e304–e312.
R. Njouom, C. G. Monamele, H. L. M. Njifon, S. Kenmoe, M. R. Njankouo, and The Network of Influenza Surveillance in Cameroon, “Circulation of Influenza Virus From 2009 to 2018 in Cameroon: 10 Years of Surveillance Data,” PLoS ONE 14, no. 12 (2019): e0225793, https://doi.org/10.1371/journal.pone.0225793.
L. S. Igboh, K. Roguski, P. Marcenac, et al., “Timing of Seasonal Influenza Epidemics for 25 Countries in Africa During 2010–19: A Retrospective Analysis,” The Lancet Global Health 11, no. 5 (2023): e729–e739.
World Health Organization, Global Epidemiological Surveillance Standards for Influenza (Geneva: World Health Organization, 2013. Available at: https://apps.who.int/iris/handle/10665/311268) accessed May 2, 2023.
M. H. Moumbeket Yifomnjou, G. C. Monamele, M. Njankouo‐Ripa, et al., “Viral Co‐Infection With Human Respiratory Syncytial Virus in Suspected Acute and Severe Respiratory Tract Infections During COVID‐19 Pandemic in Yaoundé, Cameroon, 2020–2021,” Influenza and Other Respiratory Viruses 17, no. 3 (2023): e13131, https://doi.org/10.1111/irv.13131.
P. Wang, Y. Xu, Z. Su, and C. Xie, “Impact of COVID‐19 Pandemic on Influenza Virus Prevalence in Children in Sichuan, China,” Journal of Medical Virology 95, no. 1 (2023): e28204, https://doi.org/10.1002/jmv.28204.
S. J. Olsen, E. Azziz‐Baumgartner, A. P. Budd, et al., “Decreased Influenza Activity During the COVID‐19 Pandemic—United States, Australia, Chile, and South Africa, 2020,” American Journal of Transplantation 20, no. 12 (2020): 3681–3685.
L. Zheng, J. Qi, J. Wu, and M. Zheng, “Changes in Influenza Activity and Circulating Subtypes During the COVID‐19 Outbreak in China,” Frontiers in Medicine 2023 (2022): 9, https://doi.org/10.3389/fmed.2022.829799.
C. Adlhoch, M. Sneiderman, O. Martinuka, et al., “Spotlight Influenza: The 2019/20 Influenza Season and the Impact of COVID‐19 on Influenza Surveillance in the WHO European Region,” Eurosurveillance. 26, no. 40 (2021): 2100077.
M. S. Meena, S. Priya, R. Thirukumaran, M. Gowrilakshmi, K. Essakiraja, and M. S. Madhumitha, “Factors Influencing the Acquisition of COVID Infection Among High‐Risk Contacts of COVID‐19 Patients in Madurai District‐a Case Control Study,” Journal of Family Medicine and Primary Care 11, no. 1 (2022): 182–189, https://doi.org/10.4103/jfmpc.jfmpc_355_21.
“Cameroon,” accessed December 13, 2023, https://datazone.birdlife.org/userfiles/file/IBAs/AfricaCntryPDFs/Cameroon.pdf.
H. A. Aboubakr, T. A. Sharafeldin, and S. M. Goyal, “Stability of SARS‐CoV‐2 and Other Coronaviruses in the Environment and on Common Touch Surfaces and the Influence of Climatic Conditions: A Review,” Transboundary and Emerging Diseases 68, no. 2 (2021): 296–312, https://doi.org/10.1111/tbed.13707.
M. F. F. Sobral, G. B. Duarte, A. I. G. da Penha Sobral, M. L. M. Marinho, and A. de Souza Melo, “Association Between Climate Variables and Global Transmission oF SARS‐CoV‐2,” Science of the Total Environment 729 (2020): 138997.
L. J. Wachira, R. Arena, J. F. Sallis, et al., “Why Are COVID‐19 Effects Less Severe in Sub‐Saharan Africa? Moving More and Sitting Less May Be a Primary Reason,” Progress in Cardiovascular Diseases 71 (2022): 103–105, https://doi.org/10.1016/j.pcad.2022.04.012.
C. G. Monamele, C. Kengne‐Nde, H. L. Munshili Njifon, M. R. Njankouo, S. Kenmoe, and R. Njouom, “Clinical Signs Predictive of Influenza Virus Infection in Cameroon,” PLoS ONE 15, no. 7 (2020): e0236267, https://doi.org/10.1371/journal.pone.0236267.
M. H. Ebell, I. Rahmatullah, X. Cai, et al., “A Systematic Review of Clinical Prediction Rules for the Diagnosis of Influenza,” Journal of American Board of Family Medicine 34, no. 6 (2021): 1123–1140, https://doi.org/10.3122/jabfm.2021.06.210110.
A. S. Monto, S. Gravenstein, M. Elliott, M. Colopy, and J. Schweinle, “Clinical Signs and Symptoms Predicting Influenza Infection,” Archives of Internal Medicine 160, no. 21 (2000): 3243–3247, https://doi.org/10.1001/archinte.160.21.3243.
J. R. Bosdriesz, F. Ritsema, T. Leenstra, et al., “Self‐Reported Symptoms as Predictors of SARS‐CoV‐2 Infection in the General Population Living in the Amsterdam Region, the Netherlands,” PLoS ONE 17, no. 1 (2022): e0262287, https://doi.org/10.1371/journal.pone.0262287.
A. L. Westbrook, L. C. Benedit, J. K. Frediani, et al., “Predictive Value of Isolated Symptoms for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children Tested During Peak Circulation of the Delta Variant,” Clinical Infectious Diseases 75, no. 7 (2022): 1131–1139.
M. Koutsakos, A. K. Wheatley, K. Laurie, S. J. Kent, and S. Rockman, “Influenza Lineage Extinction During the COVID‐19 Pandemic?” Nature Reviews. Microbiology 19, no. 12 (2021): 741–742, https://doi.org/10.1038/s41579‐021‐00642‐4.
Z. Vajo and P. Torzsa, “Extinction of the Influenza B Yamagata Line During the COVID Pandemic—Implications for Vaccine Composition,” Viruses 14, no. 8 (2022): 1745, https://doi.org/10.3390/v14081745.
M. C. Swets, C. D. Russell, E. M. Harrison, et al., “SARS‐CoV‐2 Co‐Infection With Influenza Viruses, Respiratory Syncytial Virus, or Adenoviruses,” The Lancet 399, no. 10334 (2022): 1463–1464, https://doi.org/10.1038/s41467‐023‐42205‐6.
K. Adams, K. J. Tastad, S. Huang, et al., “Prevalence of SARS‐CoV‐2 and Influenza Coinfection and Clinical Characteristics Among Children and Adolescents Aged 18 Years Who Were Hospitalized or Died With Influenza — United States, 2021–22 Influenza Season,” MMWR. Morbidity and Mortality Weekly Report 71 (2022): 1589–1596.
C. Y. Tang, M. Boftsi, L. Staudt, et al., “SARS‐CoV‐2 and Influenza Co‐infection: A Cross‐Sectional Study in Central Missouri During the 2021–2022 Influenza Season,” Virology 576 (2022): 105–110, https://doi.org/10.1016/j.virol.2022.09.009.
E. H. Kim, T. Q. Nguyen, M. A. B. Casel, et al., “Coinfection with SARS‐CoV‐2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4+ T Cell Responses,” Journal of Virology 96, no. 6 (2022): e01873.
A. M. McBean and P. L. Hebert, “New Estimates of Influenza‐Related Pneumonia and Influenza Hospitalizations Among the Elderly,” International Journal of Infectious Diseases 8, no. 4 (2004): 227–235.
W. W. Thompson, D. K. Shay, E. Weintraub, et al., “Influenza‐Associated Hospitalizations in the United States,” Journal of the American Medical Association 292, no. 11 (2004): 1333–1340.
G. C. Monamele, M. A. Vernet, R. F. J. Nsaibirni, et al., “Associations Between Meteorological Parameters and Influenza Activity in a Subtropical Country: Case of Five Sentinel Sites in Yaoundé‐Cameroon,” PLoS ONE 12, no. 10 (2017): e0186914, https://doi.org/10.1371/journal.pone.0186914.
Z. Akhtar, F. Chowdhury, M. Rahman, et al., “Seasonal Influenza During the COVID‐19 Pandemic in Bangladesh,” PLoS ONE 16, no. 8 (2021): e0255646.
E. Epée, N. Mandeng, J. Njuma Libwea, et al., “Two Years of Cameroon's Resilient Response to the COVID‐19 Pandemic,” Revue de L'Academie des Sciences du Cameroun. 18 (2022): 493–500.
S. M. Ghogomu, “COVID‐19: Prevention and Control Measures in Cameroon,” Revue de L'Academie des Sciences du Cameroun. 18 (2022): 537–547.
M. Lenharo, “WHO Declares End to COVID‐19's Emergency Phase,” Nature (2023), accessed May 9, 2023, https://doi.org/10.1038/d41586‐023‐01559‐z.