The impact of bladder problems on well-being in multiple sclerosis - A cross-sectional study.

Persons with multiple sclerosis (pwMS) frequently suffer from bladder problems that are not identified and managed optimally, reducing quality of life and increasing risk of health consequences. This study aimed to investigate associations between bladder problems and well-being of pwMS. The study included 1872 pwMS from France, Germany, Italy, and the UK self-reporting on demographics, MS status, bladder problems and management, and well-being. Logistic regression analyses were performed to investigate associations with self-reported well-being. Population mean age was 51 years and 79 % were women. Among pwMS, 55 % reported bladder problems indicating overactive bladder (OAB), and 40 % reported self-experienced urinary retention. Self-management of bladder problems was reported by 32 %, 33 % were yet to have problem resolution, and 45 % reported a wish to receive bladder management help. Additionally, 35 % of pwMS reported that bladder problem onset preceded awareness of a link to MS. OAB, problem self-management, and urinary complications were significantly associated with lower well-being. Bladder problems affect pwMS across disease subtypes and many attempt self-management. Consequently, pwMS with bladder problems are more likely to experience lower well-being, suggesting an unmet need. Raising awareness of the link between bladder problems and well-being could benefit pwMS living with bladder problems.

Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.

Declaration of competing interest Jalesh N. Panicker, Peter Flachenecker, Véronique Phé, Giampaolo Brichetto, and Bertil Blok are all part of the Multiple Sclerosis Consensus Board funded by Coloplast A/S. Jalesh N. Panicker is a consultant to Idorsia and Coloplast A/S, has received speaker fees from Allergan, Coloplast A/S, and Novartis, and royalties from Cambridge University Press. Peter Flachenecker has received speaker fees and honoraria for advisory boards from Almirall, Bayer, Biogen Idec, BMS-Celgene, Coloplast A/S, Genzyme, GW Pharma, Hexal, Janssen-Cilag, Novartis, Merck, Roche, Sanofi, Stadapharm, and Teva. Véronique Phé is a consultant to Boston Scientific, Coloplast A/S, Ipsen, and Medtronic. Giampaolo Brichetto has received funds for a multicenter study from Roche and has been funded by H2020 and the Italian MS Society and its Foundation for research projects. Sabrina Islamoska, Christian Riis Forman, and Kim Bundvig Barken are employees of Coloplast A/S.