An Assessment of a New Rapid Multiplex PCR Assay for the Diagnosis of Meningoencephalitis.

FilmArray ME QIAstat-Dx ME encephalitis meningitis multiplex PCR

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
11 Apr 2024
Historique:
received: 01 03 2024
revised: 28 03 2024
accepted: 08 04 2024
medline: 26 4 2024
pubmed: 26 4 2024
entrez: 26 4 2024
Statut: epublish

Résumé

The rapid and broad microbiological diagnosis of meningoencephalitis (ME) has been possible thanks to the development of multiplex PCR tests applied to cerebrospinal fluid (CSF). We aimed to assess a new multiplex PCR panel (the QIAstat-Dx ME panel), which we compared to conventional diagnostic tools and the Biofire FilmArray ME Panel. The pathogens analyzed using both methods were

Identifiants

DOI: 10.3390/diagnostics14080802 PMID: 38667448
pubmed: 38667448
pii: diagnostics14080802
doi: 10.3390/diagnostics14080802
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Genoveva Cuesta (G)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.
ORCID: 0000-0002-9031-0787

Pedro Puerta-Alcalde (P)

Department of Infectious Diseases, Hospital Clínic-IDIBAPS, University of Barcelona, 08007 Barcelona, Spain.

Andrea Vergara (A)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.
Department of Basic Clinical Practice, Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.
CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Institute of Global Health of Barcelona (ISGlobal), 08036 Barcelona, Spain.
ORCID: 0000-0002-5046-4490

Enric Roses (E)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.

Jordi Bosch (J)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.
Institute of Global Health of Barcelona (ISGlobal), 08036 Barcelona, Spain.

Climent Casals-Pascual (C)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.
Department of Basic Clinical Practice, Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.
CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Institute of Global Health of Barcelona (ISGlobal), 08036 Barcelona, Spain.

Alex Soriano (A)

Department of Infectious Diseases, Hospital Clínic-IDIBAPS, University of Barcelona, 08007 Barcelona, Spain.
CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
ORCID: 0000-0002-9374-0811

Mª Ángeles Marcos (MÁ)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.
Department of Basic Clinical Practice, Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.
CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Institute of Global Health of Barcelona (ISGlobal), 08036 Barcelona, Spain.

Sergi Sanz (S)

Department of Basic Clinical Practice, Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.
Institute of Global Health of Barcelona (ISGlobal), 08036 Barcelona, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain.
ORCID: 0000-0001-5010-4527

Jordi Vila (J)

Department of Clinical Microbiology, Hospital Clinic, 08036 Barcelona, Spain.
Department of Basic Clinical Practice, Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.
CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Institute of Global Health of Barcelona (ISGlobal), 08036 Barcelona, Spain.
ORCID: 0000-0002-8025-3926

Classifications MeSH