Intergenomic signatures of coevolution between Tasmanian devils and an infectious cancer.

co-GWAS coevolution genomics host–pathogen joint phenotype

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
19 Mar 2024
Historique:
medline: 11 3 2024
pubmed: 11 3 2024
entrez: 11 3 2024
Statut: ppublish

Résumé

Coevolution is common and frequently governs host-pathogen interaction outcomes. Phenotypes underlying these interactions often manifest as the combined products of the genomes of interacting species, yet traditional quantitative trait mapping approaches ignore these intergenomic interactions. Devil facial tumor disease (DFTD), an infectious cancer afflicting Tasmanian devils (

Identifiants

pubmed: 38466855
doi: 10.1073/pnas.2307780121
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2307780121

Subventions

Organisme : National Science Foundation (NSF)
ID : DEB 2027446
Organisme : Harvard University (Harvard College)
ID : Sarah and Daniel Hrdy Visiting Fellowship in Conservation Biology
Organisme : Australian Research Council (ARC) Future Fellowship
ID : FT100100250
Organisme : Australian Research Council (ARC) Large Grants
ID : A00000162
Organisme : Australian Research Council (ARC)
ID : DE 170101116
Organisme : Australian Research Council (ARC)
ID : LP 170101105
Organisme : Agence Nationale de la Recherche (ANR)
ID : ANR Blanc Project TRANSCAN
Organisme : Centre National de la Recherche Scientifique (CNRS)
ID : International Associated Laboratory Grant
Organisme : University of South Florida (USF)
ID : USF
Organisme : National Science Foundation (NSF)
ID : DEB 2324456

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Dylan G Gallinson (DG)

Department of Integrative Biology, University of South Florida, Tampa, FL 33620.
College of Public Health, University of South Florida, Tampa, FL 33620.

Christopher P Kozakiewicz (CP)

School of Biological Sciences, Washington State University, Pullman, WA 99163.
W.K. Kellogg Biological Station, Department of Integrative Biology, Michigan State University, Hickory Corners, MI 49060.

Rhett M Rautsaw (RM)

Department of Integrative Biology, University of South Florida, Tampa, FL 33620.
School of Biological Sciences, Washington State University, Pullman, WA 99163.

Marc A Beer (MA)

School of Biological Sciences, Washington State University, Pullman, WA 99163.

Manuel Ruiz-Aravena (M)

School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia.
Department of Public and Ecosystem Health, Cornell University, Ithaca, NY 14853.

Sebastien Comte (S)

School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia.
New South Wales Department of Primary Industries, Vertebrate Pest Research Unit, Orange, NSW 2800, Australia.

David G Hamilton (DG)

School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia.

Douglas H Kerlin (DH)

Centre for Planetary Health and Food Security, Griffith University, Nathan, QLD 4111, Australia.

Hamish I McCallum (HI)

Centre for Planetary Health and Food Security, Griffith University, Nathan, QLD 4111, Australia.

Rodrigo Hamede (R)

School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia.
CANECEV Centre de Recherches Ecologiques et Evolutives sur le Cancer, Montpellier 34394, France.

Menna E Jones (ME)

School of Natural Sciences, University of Tasmania, Hobart, TAS 7001, Australia.

Andrew Storfer (A)

School of Biological Sciences, Washington State University, Pullman, WA 99163.

Ryan McMinds (R)

Department of Integrative Biology, University of South Florida, Tampa, FL 33620.
College of Public Health, University of South Florida, Tampa, FL 33620.

Mark J Margres (MJ)

Department of Integrative Biology, University of South Florida, Tampa, FL 33620.

Classifications MeSH