Sudden hearing loss secondary to syphilis.

Neurosyphilis Serology Sudden hearing loss Syphilis

Journal

American journal of otolaryngology
ISSN: 1532-818X
Titre abrégé: Am J Otolaryngol
Pays: United States
ID NLM: 8000029

Informations de publication

Date de publication:
28 Feb 2024
Historique:
received: 13 11 2023
revised: 23 01 2024
accepted: 21 02 2024
medline: 3 3 2024
pubmed: 3 3 2024
entrez: 2 3 2024
Statut: aheadofprint

Résumé

Syphilis is a sexually transmitted disease caused by the spirochete Treponema pallidum, whose incidence has increased significantly in recent years. Some patients may develop sudden hearing loss (SHL) against the background of otosyphilis. The objective of our study was to determine whether routine lues serology is useful in patients presenting with sudden hearing loss. For this purpose, all cases of SHL treated in our hospital during a period of 6 years were propectively collected. The frequency of positivity for syphilis in these patients, the treatment received, and their evolution were determined. Of the total number of patients evaluated during that period, 71 underwent serological screening for syphilis, of whom 2 (2.8 %) presented positive screening antibodies. In one of them, the RPR was normal and had been treated with lues a few years before. After treatment there was no improvement. The other patient, diagnosed with otosyphilis with unconfirmed suspected neurological disease, showed normalization of hearing after specific treatment. Since it is a potentially curable disease, despite the low overall frequency of syphilis in patients with SHL it is advisable to perform serological screening for syphilis in high risk patients (e.g., incarceration, multiple recent sexual partners, men who have sex with men) or atypical clinical presentation (e.g., concurrent neuropathies).

Sections du résumé

BACKGROUND BACKGROUND
Syphilis is a sexually transmitted disease caused by the spirochete Treponema pallidum, whose incidence has increased significantly in recent years. Some patients may develop sudden hearing loss (SHL) against the background of otosyphilis.
OBJECTIVES OBJECTIVE
The objective of our study was to determine whether routine lues serology is useful in patients presenting with sudden hearing loss.
METHODS METHODS
For this purpose, all cases of SHL treated in our hospital during a period of 6 years were propectively collected. The frequency of positivity for syphilis in these patients, the treatment received, and their evolution were determined.
RESULTS RESULTS
Of the total number of patients evaluated during that period, 71 underwent serological screening for syphilis, of whom 2 (2.8 %) presented positive screening antibodies. In one of them, the RPR was normal and had been treated with lues a few years before. After treatment there was no improvement. The other patient, diagnosed with otosyphilis with unconfirmed suspected neurological disease, showed normalization of hearing after specific treatment.
CONCLUSIONS CONCLUSIONS
Since it is a potentially curable disease, despite the low overall frequency of syphilis in patients with SHL it is advisable to perform serological screening for syphilis in high risk patients (e.g., incarceration, multiple recent sexual partners, men who have sex with men) or atypical clinical presentation (e.g., concurrent neuropathies).

Identifiants

pubmed: 38430842
pii: S0196-0709(24)00020-6
doi: 10.1016/j.amjoto.2024.104234
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104234

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors report there are no competing interests to declare.

Auteurs

Minerva Rodríguez-Martín (M)

Department of Otolaryngology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

Elena Cantón-Benito (E)

Department of Microbiology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

José Manuel Méndez-Legaza (JM)

Department of Microbiology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

Aida Veiga-Alonso (A)

Department of Otolaryngology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

Rocío González-Aguado (R)

Department of Otolaryngology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

Carmelo Morales-Angulo (C)

Department of Otolaryngology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain; Faculty of Medicine, University of Cantabria, Spain; IDIVAL, Santander, Cantabria, Spain. Electronic address: carmelo.morales@unican.es.

Classifications MeSH