Cannabidiol protects C2C12 myotubes against cisplatin-induced atrophy by regulating oxidative stress.
cachexia
endocannabinoid system
mitochondrial function
oxidative stress
protein homeostasis
Journal
American journal of physiology. Cell physiology
ISSN: 1522-1563
Titre abrégé: Am J Physiol Cell Physiol
Pays: United States
ID NLM: 100901225
Informations de publication
Date de publication:
26 Feb 2024
26 Feb 2024
Historique:
medline:
26
2
2024
pubmed:
26
2
2024
entrez:
26
2
2024
Statut:
aheadofprint
Résumé
Cancer and chemotherapy can both cause cachexia, a complex multi-organ syndrome characterized by body weight loss, due to adipose tissue and skeletal muscle wasting. Changes in body weight and muscle mass are predictive of response to chemotherapy, incidence of treatment-related complications and, ultimately, patient survival, but there are currently still no clear therapeutic strategies to counteract cachexia. Cannabidiol (CBD) is a bioactive phytocannabinoid produced from a plant named
Identifiants
pubmed: 38406827
doi: 10.1152/ajpcell.00622.2023
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM