TRPV4 Channels Promote Pathological, but Not Physiological, Cardiac Remodeling through the Activation of Calcineurin/NFAT and TRPC6.

TRP TRPC6 TRPV4 calcium exercise heart failure mechanoreceptors mechanotransduction pathological remodeling physiological remodeling

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
26 Jan 2024
Historique:
received: 09 11 2023
revised: 10 01 2024
accepted: 22 01 2024
medline: 10 2 2024
pubmed: 10 2 2024
entrez: 10 2 2024
Statut: epublish

Résumé

TRPV4 channels, which respond to mechanical activation by permeating Ca

Identifiants

DOI: 10.3390/ijms25031541 PMID: 38338818
pubmed: 38338818
pii: ijms25031541
doi: 10.3390/ijms25031541
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Instituto de Salud Carlos III - Fondo de Investigación Sanitaria
ID : PI16/00619
Organisme : Sociedad Española de Cardiología
ID : SEC/FEC-INV-BAS 20/016
Organisme : Societat Catalana de Cardiologia
ID : 2021

Auteurs

Laia Yáñez-Bisbe (L)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.

Mar Moya (M)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.

Antonio Rodríguez-Sinovas (A)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
ORCID: 0000-0003-2930-8773

Marisol Ruiz-Meana (M)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Javier Inserte (J)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
ORCID: 0000-0002-4736-5010

Marta Tajes (M)

Bio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, 08908 Barcelona, Spain.

Montserrat Batlle (M)

Institute for Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
ORCID: 0000-0002-3034-2023

Eduard Guasch (E)

Institute for Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Cardiology Department, Hospital Clínic, 08036 Barcelona, Spain.
ORCID: 0000-0003-4238-5319

Aleksandra Mas-Stachurska (A)

Institute for Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.

Elisabet Miró (E)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.

Nuria Rivas (N)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.

Ignacio Ferreira González (I)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Department of Medicine, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.
Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Anna Garcia-Elias (A)

Department of Clinical Research, ASCIRES-CETIR Biomedic Group, 08029 Barcelona, Spain.

Begoña Benito (B)

Cardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Cardiology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Department of Medicine, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.

Classifications MeSH