Effect of acute resistance exercise on bone turnover in young adults before and after concurrent resistance and interval training.
adaptive bone formation
bone turnover
muscle-bone crosstalk
sex differences
Journal
Physiological reports
ISSN: 2051-817X
Titre abrégé: Physiol Rep
Pays: United States
ID NLM: 101607800
Informations de publication
Date de publication:
Feb 2024
Feb 2024
Historique:
revised:
11
12
2023
received:
07
10
2023
accepted:
11
12
2023
medline:
1
2
2024
pubmed:
1
2
2024
entrez:
31
1
2024
Statut:
ppublish
Résumé
Weight-bearing physical activity can stimulate bone adaptation. This investigation explored the effect of an acute bout of resistance exercise before and after resistance+interval training on circulating biomarkers of bone metabolism and muscle-bone crosstalk. Healthy young male and female participants (n = 21 male, 28 ± 4 years; n = 17 female, 27 ± 5 years) performed a 6 × 10 squat test (75% 1RM) before and after a 12-week resistance+interval training program. Before and after completion of the training program, blood samples were collected at rest, immediately postexercise, and 2 h postexercise. Blood samples were analyzed for βCTX, P1NP, sclerostin, osteocalcin, IGF-1, and irisin. Significant effects of acute exercise (main effect of time) were observed as increases in concentrations of IGF-1, irisin, osteocalcin, and P1NP from rest to postexercise. A sex*time interaction indicated a greater decline in βCTX concentration from rest to 2 h postexercise and a greater increase in sclerostin concentration from rest to immediately postexercise in male compared with female participants. Sex differences (main effect of sex) were also observed for irisin and P1NP concentrations. In summary, changes in concentrations of biochemical markers of bone metabolism and muscle-bone crosstalk were observed in males and females after an acute bout of resistance exercise and following 12 weeks of resistance+interval training.
Identifiants
pubmed: 38296351
doi: 10.14814/phy2.15906
pmc: PMC10830389
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e15906Subventions
Organisme : UK Ministry of Defence
ID : WGCC 5.5.6-Task 0107
Informations de copyright
© 2024 Crown copyright. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society. This article is published with the permission of the Controller of HMSO and the King's Printer for Scotland.
Références
Exp Biol Med (Maywood). 2017 May;242(9):897-906
pubmed: 27496801
Bone. 2022 Jul;160:116426
pubmed: 35470123
J Bone Miner Res. 2005 Mar;20(3):529-35
pubmed: 15746999
Int J Endocrinol. 2014;2014:902186
pubmed: 24723951
Front Endocrinol (Lausanne). 2019 Jan 10;9:794
pubmed: 30687236
J Strength Cond Res. 2015 Nov;29 Suppl 11:S101-6
pubmed: 26506171
Sports Med. 2022 Dec;52(12):2889-2908
pubmed: 35870108
Med Sci Sports Exerc. 2019 Oct;51(10):2117-2124
pubmed: 31009423
Curr Osteoporos Rep. 2020 Aug;18(4):388-400
pubmed: 32529456
Bone. 2002 Jul;31(1):57-61
pubmed: 12110413
Med Sci Sports Exerc. 2011 Apr;43(4):617-23
pubmed: 20798655
Exerc Sport Sci Rev. 2020 Jul;48(3):140-148
pubmed: 32568926
Bone. 2009 Oct;45(4):768-76
pubmed: 19520194
Eur J Sport Sci. 2023 Dec;23(12):2411-2424
pubmed: 37517090
J Appl Physiol (1985). 2023 Jan 1;134(1):85-94
pubmed: 36454676
Scand J Med Sci Sports. 2018 Jan;28(1):16-28
pubmed: 28453881
J Sci Med Sport. 2023 Jun;26 Suppl 1:S14-S21
pubmed: 37188615
J Appl Physiol (1985). 2022 Jul 1;133(1):170-182
pubmed: 35678743
Med Sci Sports Exerc. 2008 Nov;40(11 Suppl):S660-70
pubmed: 18849868
J Clin Endocrinol Metab. 2010 Aug;95(8):3918-25
pubmed: 20519353
Physiol Rep. 2024 Feb;12(3):e15906
pubmed: 38296351
Osteoporos Int. 2000;11(6):512-7
pubmed: 10982167
J Physiol Biochem. 2011 Sep;67(3):351-8
pubmed: 21394549
Mil Med. 2011 Apr;176(4):420-30
pubmed: 21539165
Front Endocrinol (Lausanne). 2022 Jun 30;13:915241
pubmed: 35846315
Eur J Clin Invest. 2014 Feb;44(2):119-24
pubmed: 24188288
Front Physiol. 2023 Jan 04;13:1049604
pubmed: 36685198
Exp Gerontol. 2022 Jan;157:111633
pubmed: 34826573
Biol Res Nurs. 2022 Apr;24(2):152-162
pubmed: 34719994
Med Sci Sports Exerc. 2004 Nov;36(11):1985-96
pubmed: 15514517
Eur J Sport Sci. 2022 Jan;22(1):43-57
pubmed: 34006204
Growth Horm IGF Res. 2021 Aug;59:101407
pubmed: 34118743
Bone. 2017 Mar;96:85-90
pubmed: 27744012
Biomed Res Int. 2018 Nov 1;2018:4864952
pubmed: 30515401
Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12157-62
pubmed: 26374841
J Appl Physiol (1985). 2011 Nov;111(5):1353-60
pubmed: 21868687
J Biol Chem. 2008 Feb 29;283(9):5866-75
pubmed: 18089564
Mil Med. 2016 Oct;181(10):1308-1313
pubmed: 27753569
US Army Med Dep J. 2013 Oct-Dec;:5-23
pubmed: 24146239
Mil Med. 2016 Jan;181(1 Suppl):50-62
pubmed: 26741902
J Appl Physiol (1985). 2011 Feb;110(2):423-32
pubmed: 21127210
Sci Rep. 2017 Jun 6;7(1):2811
pubmed: 28588307
J Sci Med Sport. 2017 Nov;20 Suppl 4:S91-S97
pubmed: 28986086
J Orthop Surg Res. 2021 Oct 17;16(1):609
pubmed: 34657598
Bone. 2018 Aug;113:9-16
pubmed: 29709620
Calcif Tissue Int. 2017 Aug;101(2):170-173
pubmed: 28374174
Med Sci Sports Exerc. 2017 Jul;49(7):1437-1442
pubmed: 28248693
Front Physiol. 2022 Feb 11;13:803219
pubmed: 35222074
J Bone Miner Res. 1997 Apr;12(4):656-62
pubmed: 9101378
J Bone Miner Res. 2018 Jul;33(7):1326-1334
pubmed: 29572961
J Clin Endocrinol Metab. 2012 Jan;97(1):148-54
pubmed: 21994959
J Clin Endocrinol Metab. 2014 Sep;99(9):3247-55
pubmed: 24915120
Exerc Sport Sci Rev. 2003 Jan;31(1):45-50
pubmed: 12562170
PLoS One. 2015 May 13;10(5):e0123302
pubmed: 25970439
Front Nutr. 2022 Apr 29;9:840973
pubmed: 35571916
Int J Sports Med. 2004 Oct;25(7):496-501
pubmed: 15459829
J Endocrinol Invest. 2022 Feb;45(2):391-397
pubmed: 34390461
J Musculoskelet Neuronal Interact. 2015 Mar;15(1):23-31
pubmed: 25730649
J Appl Physiol (1985). 2015 Oct 1;119(7):824-30
pubmed: 26251510