Antibiofilm and Antivirulence Properties of 6-Polyaminosteroid Derivatives against Antibiotic-Resistant Bacteria.
6-aminosteroid derivatives
antibiofilm
antivirulence
pyocyanin
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
20 Dec 2023
20 Dec 2023
Historique:
received:
29
11
2023
revised:
15
12
2023
accepted:
18
12
2023
medline:
26
1
2024
pubmed:
26
1
2024
entrez:
26
1
2024
Statut:
epublish
Résumé
The emergence of multi-drug resistant pathogens is a major public health problem, leading us to rethink and innovate our bacterial control strategies. Here, we explore the antibiofilm and antivirulence activities of nineteen 6-polyaminosterol derivatives (squalamine-based), presenting a modulation of their polyamine side chain on four major pathogens, i.e., carbapenem-resistant
Identifiants
pubmed: 38275318
pii: antibiotics13010008
doi: 10.3390/antibiotics13010008
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Région Normandie
ID : RN-3A