Determinants and reference values of the 6-min walk distance in the general population-results of the population-based STAAB cohort study.
Cardiopulmonary exercise capacity
Functional capacity
Normal values
Online calculator
Physical fitness
Six-minute walk test
Journal
Clinical research in cardiology : official journal of the German Cardiac Society
ISSN: 1861-0692
Titre abrégé: Clin Res Cardiol
Pays: Germany
ID NLM: 101264123
Informations de publication
Date de publication:
18 Jan 2024
18 Jan 2024
Historique:
received:
12
07
2023
accepted:
31
12
2023
medline:
18
1
2024
pubmed:
18
1
2024
entrez:
18
1
2024
Statut:
aheadofprint
Résumé
The 6-min walk test is an inexpensive, safe, and easy tool to assess functional capacity in patients with cardiopulmonary diseases including heart failure (HF). There is a lack of reference values, which are a prerequisite for the interpretation of test results in patients. Furthermore, determinants independent of the respective disease need to be considered when interpreting the 6-min walk distance (6MWD). The prospective Characteristics and Course of Heart Failure Stages A-B and Determinants of Progression (STAAB) cohort study investigates a representative sample of residents of the City of Würzburg, Germany, aged 30 to 79 years, without a history of HF. Participants underwent detailed clinical and echocardiographic phenotyping as well as a standardized assessment of the 6MWD using a 15-m hallway. In a sample of 2762 participants (51% women, mean age 58 ± 11 years), we identified age and height, but not sex, as determinants of the 6MWD. While a worse metabolic profile showed a negative association with the 6MWD, a better systolic and diastolic function showed a positive association with 6MWD. From a subgroup of 681 individuals without any cardiovascular risk factors (60% women, mean age 52 ± 10 years), we computed age- and height-specific reference percentiles. In a representative sample of the general population free from HF, we identified determinants of the 6MWD implying objective physical fitness associated with metabolic health as well as with cardiac structure and function. Furthermore, we derived reference percentiles applicable when using a 15-m hallway.
Identifiants
pubmed: 38236418
doi: 10.1007/s00392-023-02373-3
pii: 10.1007/s00392-023-02373-3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Bundesministerium für Bildung und Forschung
ID : BMBF 01EO1004
Organisme : Bundesministerium für Bildung und Forschung
ID : BMBF 01EO1504
Investigateurs
C Maack
(C)
G Ertl
(G)
M Fassnacht
(M)
C Wanner
(C)
R Leyh
(R)
J Volkmann
(J)
J Deckert
(J)
H Faller
(H)
R Jahns
(R)
Informations de copyright
© 2024. The Author(s).
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