Characterizing fibril morphological changes by spirooxindoles for neurodegenerative disease application.


Journal

The Analyst
ISSN: 1364-5528
Titre abrégé: Analyst
Pays: England
ID NLM: 0372652

Informations de publication

Date de publication:
15 Jan 2024
Historique:
medline: 15 1 2024
pubmed: 15 1 2024
entrez: 15 1 2024
Statut: aheadofprint

Résumé

Fibrillation of proteins and polypeptides, which leads to the deposition of plaques in cells and tissues has been widely associated with many neuropathological diseases. Inhibition of protein misfolding and aggregation is crucial for the prevention and treatment of these conditions. The growing interest in identifying inhibitor molecules to prevent the formation of fibrils

Identifiants

pubmed: 38224234
doi: 10.1039/d3an01773g
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Anthony Dahdah (A)

School of Science, STEM College, RMIT University, 124 La Trobe Street, Melbourne, VIC, 3001, Australia. Ewan.blanch@rmit.edu.au.

Nilamuni H de Silva (NH)

School of Science, STEM College, RMIT University, 124 La Trobe Street, Melbourne, VIC, 3001, Australia. Ewan.blanch@rmit.edu.au.

Subashani Maniam (S)

School of Science, STEM College, RMIT University, 124 La Trobe Street, Melbourne, VIC, 3001, Australia. Ewan.blanch@rmit.edu.au.

Ewan W Blanch (EW)

School of Science, STEM College, RMIT University, 124 La Trobe Street, Melbourne, VIC, 3001, Australia. Ewan.blanch@rmit.edu.au.

Classifications MeSH