Curcumin-PVP improves the in vitro efficacy of ivermectin against resistant and susceptible Haemonchus contortus.

Curcumin Detoxification In vitro Infecting larvae Larval migration inhibition

Journal

Experimental parasitology
ISSN: 1090-2449
Titre abrégé: Exp Parasitol
Pays: United States
ID NLM: 0370713

Informations de publication

Date de publication:
11 Dec 2023
Historique:
received: 19 05 2023
revised: 10 08 2023
accepted: 05 12 2023
medline: 14 12 2023
pubmed: 14 12 2023
entrez: 13 12 2023
Statut: aheadofprint

Résumé

Ivermectin (IVM) resistance in parasitic nematodes such as Haemonchus contortus has spurred a search for substances that help to recover its efficacy. One potential agent is the natural product curcumin (CUR). In this study, CUR was combined with polyvinylpyrrolidone (PVP) (CUR/PVP) to improve its solubility and biological applicability. This study determined the effect of CUR preincubation on the EC

Identifiants

DOI: 10.1016/j.exppara.2023.108670 PMID: 38092297
pubmed: 38092297
pii: S0014-4894(23)00211-4
doi: 10.1016/j.exppara.2023.108670
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108670

Informations de copyright

Copyright © 2023. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest On behalf of my co-authors, we are submitting the manuscript entitled: “Curcumin-PVP improves the in vitro efficacy of ivermectin against resistant and susceptible Haemonchus contortus”, by Lisandro Alberto Encalada-Mena, Raquel López-Arellano, María Eugenia López-Arellano, María Gabriela Mancilla-Montelongo, Carlos Alfredo Sandoval-Castro, Agustín Olmedo-Juárez, Adrián Lifschitz and Juan Felipe de Jesús Torres-Acosta. We declare that this is an original contribution that has not been published elsewhere in substantially the same form and it is not currently under consideration elsewhere. Furthermore, we have no financial or personal interest that could be considered a conflict of interest.

Auteurs

Lisandro Alberto Encalada-Mena (LA)

Facultad de Ciencias Agropecuarias, Universidad Autónoma de Campeche, Calle 53 S/N, Col. Unidad, Esfuerzo y Trabajo No. 2, C.P. 24350, Campeche, Mexico.

Raquel López-Arellano (R)

Laboratorio de Ensayos de Desarrollo Farmacéutico, Unidad de Investigación Multidisciplinaria, FES-Cuautitlán, Campo 4, Universidad Nacional Autónoma de México, Carr. México-Teoloyucan Km 2.5 San Sebastián Xhala, C.P. 54714, Cuautitlán Izcalli, Estado de México, Mexico.

María Eugenia López-Arellano (ME)

Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias, Carr. Fed. Cuernavaca-Cuautla, No. 8534, C.P. 62550, Jiutepec, Morelos, Mexico.

María Gabriela Mancilla-Montelongo (MG)

CONACYT-Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Km 15.5 Carr. Mérida-Xmatkuil, C.P. 97315, Mérida, Yucatán, Mexico.

Carlos Alfredo Sandoval-Castro (CA)

Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Km 15.5 Carr. Mérida-Xmatkuil, C.P. 97315, Mérida, Yucatán, Mexico.

Agustín Olmedo-Juárez (A)

Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias, Carr. Fed. Cuernavaca-Cuautla, No. 8534, C.P. 62550, Jiutepec, Morelos, Mexico.

Adrián Lifschitz (A)

Laboratorio de Farmacología, Centro de Investigación Veterinaria de Tandil (CIVETAN), UNCPBA-CICPBA-CONICET, Campus Universitario, Tandil, 7000, Argentina.

Juan Felipe de Jesús Torres-Acosta (JFJ)

Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Km 15.5 Carr. Mérida-Xmatkuil, C.P. 97315, Mérida, Yucatán, Mexico. Electronic address: tacosta@correo.uady.mx.

Classifications MeSH