Chromosomal Instability in Gastric Cancer: Role in Tumor Development, Progression, and Therapy.
aneuploidy
chromosomal instability
driver genes
gastric cancer
structural rearrangements of chromosomal loci
subtype of gastric cancer with chromosomal instability
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
30 Nov 2023
30 Nov 2023
Historique:
received:
26
10
2023
revised:
23
11
2023
accepted:
29
11
2023
medline:
9
12
2023
pubmed:
9
12
2023
entrez:
9
12
2023
Statut:
epublish
Résumé
According to the Cancer Genome Atlas (TCGA), gastric cancers are classified into four molecular subtypes: Epstein-Barr virus-positive (EBV+), tumors with microsatellite instability (MSI), tumors with chromosomal instability (CIN), and genomically stable (GS) tumors. However, the gastric cancer (GC) with chromosomal instability remains insufficiently described and does not have effective markers for molecular and histological verification and diagnosis. The CIN subtype of GC is characterized by chromosomal instability, which is manifested by an increased frequency of aneuploidies and/or structural chromosomal rearrangements in tumor cells. Structural rearrangements in the CIN subtype of GC are not accidental and are commonly detected in chromosomal loci, being abnormal because of specific structural organization. The causes of CIN are still being discussed; however, according to recent data, aberrations in the
Identifiants
pubmed: 38069284
pii: ijms242316961
doi: 10.3390/ijms242316961
pmc: PMC10707305
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Russian Science Foundation
ID : 20-75-10117-П
Références
Clin Cancer Res. 1998 Apr;4(4):973-7
pubmed: 9563892
Comput Struct Biotechnol J. 2015 Aug 13;13:448-58
pubmed: 26380657
Oncogene. 2009 Feb 12;28(6):866-75
pubmed: 19060929
Anticancer Agents Med Chem. 2020;20(7):758-767
pubmed: 32013835
BMC Med Genomics. 2012 May 04;5:14
pubmed: 22559327
World J Gastroenterol. 2013 Oct 7;19(37):6165-9
pubmed: 24115812
Front Cell Dev Biol. 2020 Dec 07;8:620164
pubmed: 33365314
Breast Cancer (Dove Med Press). 2023 Mar 09;15:189-211
pubmed: 36923397
J Clin Oncol. 2011 Dec 20;29(36):4789-95
pubmed: 22042954
Cancers (Basel). 2023 Feb 04;15(4):
pubmed: 36831343
Genes (Basel). 2020 Jun 10;11(6):
pubmed: 32532049
Gastric Cancer. 2016 Jan;19(1):63-73
pubmed: 25487305
US Gastroenterol Hepatol Rev. 2011 Jun;7(1):59-64
pubmed: 21857882
Cancer Sci. 2018 Feb;109(2):412-421
pubmed: 29168598
Front Pharmacol. 2018 Aug 02;9:847
pubmed: 30116193
Nat Med. 2015 May;21(5):449-56
pubmed: 25894828
Gastric Cancer. 2021 Jan;24(1):1-21
pubmed: 32060757
Int J Cancer. 2015 Mar 1;136(5):E359-86
pubmed: 25220842
Am Soc Clin Oncol Educ Book. 2021 Mar;41:1-8
pubmed: 34010049
Cell Rep. 2016 Mar 29;14(12):2975-87
pubmed: 26997271
Nat Biotechnol. 2012 May;30(5):413-21
pubmed: 22544022
Aging (Albany NY). 2020 Jan 25;12(2):1304-1321
pubmed: 31982864
Nat Genet. 2018 Aug;50(8):1189-1195
pubmed: 30013179
Ann Oncol. 2001;12 Suppl 1:S9-13
pubmed: 11521729
Gene. 2014 Aug 10;546(2):288-96
pubmed: 24879917
Life (Basel). 2020 Nov 08;10(11):
pubmed: 33171596
Arch Pathol Lab Med. 2004 Jul;128(7):765-70
pubmed: 15214826
Nat Rev Drug Discov. 2023 Feb;22(2):127-144
pubmed: 36216888
Eur J Cancer. 2020 May;130:23-31
pubmed: 32171106
ScientificWorldJournal. 2020 Mar 10;2020:6845413
pubmed: 32231466
Gene. 2013 Oct 15;529(1):69-72
pubmed: 23954221
Am J Surg Pathol. 2020 Aug;44(8):1017-1030
pubmed: 32568823
Exp Cell Res. 2014 Nov 15;329(1):85-93
pubmed: 25281304
Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17579-84
pubmed: 23045701
Dig Surg. 2013;30(2):150-8
pubmed: 23867592
Trends Cell Biol. 2011 Jun;21(6):374-81
pubmed: 21306900
Cell. 2018 Sep 6;174(6):1347-1360
pubmed: 30193109
Cancer Manag Res. 2020 Aug 05;12:6947-6958
pubmed: 32801915
Signal Transduct Target Ther. 2022 Oct 8;7(1):358
pubmed: 36209270
Science. 1997 Mar 21;275(5307):1787-90
pubmed: 9065402
Med Oncol. 2011 Dec;28(4):1017-22
pubmed: 20585902
Virchows Arch. 2018 Dec;473(6):687-695
pubmed: 30140949
BMC Res Notes. 2014 Apr 29;7:271
pubmed: 24774510
World J Gastroenterol. 2012 May 21;18(19):2402-7
pubmed: 22654433
Cancers (Basel). 2021 Feb 22;13(4):
pubmed: 33671606
Signal Transduct Target Ther. 2020 Jul 10;5(1):124
pubmed: 32651356
BMC Med Genomics. 2019 Dec 23;12(1):198
pubmed: 31870357
Oncotarget. 2017 Sep 11;8(44):78234-78244
pubmed: 29100463
Am J Cancer Res. 2021 May 15;11(5):1913-1935
pubmed: 34094661
J Gastroenterol Hepatol. 2007 Sep;22(9):1435-42
pubmed: 17573829
Biochim Biophys Acta Rev Cancer. 2022 Jan;1877(1):188661
pubmed: 34800547
Nature. 2014 Sep 11;513(7517):202-9
pubmed: 25079317
Br J Cancer. 2021 Dec;125(12):1621-1631
pubmed: 34671125
Gastric Cancer. 2016 Jan;19(1):42-52
pubmed: 25424150
Ann Oncol. 2013 Sep;24(9):2360-4
pubmed: 23788757
Br J Surg. 2001 Mar;88(3):419-25
pubmed: 11260110
PLoS One. 2018 Sep 13;13(9):e0202576
pubmed: 30212456
Pharmacogenomics J. 2012 Apr;12(2):119-27
pubmed: 21173787
Nature. 2022 Jun;606(7916):976-983
pubmed: 35705807
Surg Clin North Am. 2017 Apr;97(2):345-370
pubmed: 28325191
Hum Cell. 2022 Mar;35(2):678-693
pubmed: 35088239
Nat Commun. 2023 Jul 20;14(1):4387
pubmed: 37474499
Ann Surg Oncol. 2012 Oct;19(11):3491-9
pubmed: 22588468
Science. 2004 Apr 23;304(5670):554
pubmed: 15016963
Nat Rev Clin Oncol. 2018 Mar;15(3):139-150
pubmed: 29297505
Cell. 2017 Sep 7;170(6):1062-1078
pubmed: 28886379
Nat Rev Mol Cell Biol. 2009 Jul;10(7):478-87
pubmed: 19546858
Oncogene. 2015 Jan 8;34(2):199-208
pubmed: 24362523
Nature. 2008 Sep 4;455(7209):119-23
pubmed: 18615013
Nat Genet. 2004 Jan;36(1):55-62
pubmed: 14702041
Oncogene. 2016 Mar 24;35(12):1475-82
pubmed: 26073079
Br J Cancer. 1996 Feb;73(4):424-8
pubmed: 8595154
Mol Cancer. 2021 Jan 15;20(1):15
pubmed: 33451333
PLoS One. 2011 Jan 31;6(1):e14632
pubmed: 21297939
Cancer Res. 2001 Apr 15;61(8):3230-9
pubmed: 11309271
J Gastrointest Oncol. 2017 Jun;8(3):583-588
pubmed: 28736645
Oncotarget. 2017 Apr 4;8(14):23937-23954
pubmed: 28147341
Therap Adv Gastroenterol. 2018 Nov 14;11:1756284818808072
pubmed: 30455742
Adv Mod Oncol Res. 2016;2(4):215-223
pubmed: 27642640
Mol Cancer Res. 2017 Jun;15(6):708-713
pubmed: 28184012
J Cell Biol. 2015 Aug 3;210(3):373-83
pubmed: 26240182
Curr Treat Options Oncol. 2015 Apr;16(4):17
pubmed: 25813036
Med Oncol. 2022 Apr 29;39(6):106
pubmed: 35486263
J Cell Sci. 1999 Nov;112 ( Pt 21):3591-601
pubmed: 10523496
Nat Commun. 2020 Mar 25;11(1):1557
pubmed: 32214089
Virchows Arch. 2018 Nov;473(5):559-565
pubmed: 30120594
Oncologist. 2012;17(5):653-62
pubmed: 22531355
BMC Genomics. 2007 Oct 01;8:345
pubmed: 17908304
Trends Genet. 2008 Feb;24(2):64-9
pubmed: 18192061
Oncol Lett. 2019 Nov;18(5):4651-4658
pubmed: 31611974
Oncol Lett. 2021 Jul;22(1):557
pubmed: 34084224
Nucleic Acids Res. 2016 Oct 14;44(18):8772-8785
pubmed: 27382066
Cancer Res. 2007 Jun 1;67(11):5362-70
pubmed: 17545617
Neoplasia. 2017 May;19(5):412-420
pubmed: 28431273
Rev Esp Enferm Dig. 2011 Dec;103(12):632-9
pubmed: 22217347
Br J Surg. 2022 Feb 24;109(3):291-297
pubmed: 35179206
Cancer Discov. 2022 Jan;12(1):31-46
pubmed: 35022204
Oncol Lett. 2016 May;11(5):2959-2964
pubmed: 27123046
J Gastrointest Oncol. 2012 Sep;3(3):251-61
pubmed: 22943016
Mol Cell Biol. 2002 Feb;22(3):874-85
pubmed: 11784863
Trends Cell Biol. 1999 Nov;9(11):454-9
pubmed: 10511710
BMC Womens Health. 2015;15:24
pubmed: 25783654
Tumour Biol. 2014 Jul;35(7):6815-21
pubmed: 24729090
Curr Treat Options Oncol. 2015 Jul;16(7):30
pubmed: 26031544
Int J Biol Markers. 2022 Sep;37(3):296-305
pubmed: 35722719
Br J Cancer. 2002 Aug 12;87(4):432-40
pubmed: 12177780
Med Oncol. 2022 Jun 20;39(9):133
pubmed: 35723742
Cell Death Differ. 2015 Aug;22(8):1239-49
pubmed: 26024390
N Engl J Med. 2020 Jun 18;382(25):2419-2430
pubmed: 32469182
Sci Rep. 2021 Jan 14;11(1):1331
pubmed: 33446695
Hum Mol Genet. 2008 Jan 15;17(2):215-24
pubmed: 17925329
J Cell Sci. 2004 May 15;117(Pt 12):2523-31
pubmed: 15128871
Clin Transl Oncol. 2012 Jan;14(1):60-5
pubmed: 22262720
Lancet. 2017 Dec 2;390(10111):2461-2471
pubmed: 28993052
Subcell Biochem. 2014;85:187-97
pubmed: 25201195
Nature. 2017 Jan 12;541(7636):182-187
pubmed: 28052057
J Transl Med. 2019 Jun 4;17(1):189
pubmed: 31164161
Int J Clin Exp Med. 2015 Jul 15;8(7):11692-700
pubmed: 26380006