The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes.
Journal
Nature immunology
ISSN: 1529-2916
Titre abrégé: Nat Immunol
Pays: United States
ID NLM: 100941354
Informations de publication
Date de publication:
04 Dec 2023
04 Dec 2023
Historique:
received:
06
12
2022
accepted:
27
10
2023
medline:
5
12
2023
pubmed:
5
12
2023
entrez:
4
12
2023
Statut:
aheadofprint
Résumé
Intestinal intraepithelial lymphocytes (IELs) exhibit prompt innate-like responses to microenvironmental cues and require strict control of effector functions. Here we showed that Aiolos, an Ikaros zinc-finger family member encoded by Ikzf3, acted as a regulator of IEL activation. Ikzf3
Identifiants
pubmed: 38049581
doi: 10.1038/s41590-023-01693-w
pii: 10.1038/s41590-023-01693-w
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIAID NIH HHS
ID : U19 AI142733
Pays : United States
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.
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